Western University research could lead to better treatments for PTSD and drug addiction

Published on December 6, 2012 at 1:15 AM · No Comments

New research from Western University could lead to better treatments for Post-Traumatic Stress Disorder (PTSD) and drug addiction by effectively blocking memories. The research performed by Nicole Lauzon, a PhD candidate in the laboratory of Steven Laviolette at Western's Schulich School of Medicine & Dentistry has revealed a common mechanism in a region of the brain called the pre-limbic cortex, can control the recall of memories linked to both aversive, traumatic experiences associated with PTSD and rewarding memories linked to drug addiction. More importantly, the researchers have discovered a way to actively suppress the spontaneous recall of both types of memories, without permanently altering memories. The findings are published online in the journal Neuropharmacology.

"These findings are very important in disorders like PTSD or drug addiction. One of the common problems associated with these disorders is the obtrusive recall of memories that are associated with the fearful, emotional experiences in PTSD patients. And people suffering with addiction are often exposed to environmental cues that remind them of the rewarding effects of the drug. This can lead to drug relapse, one of the major problems with persistent addictions to drugs such as opiates," explains Laviolette, an associate professor in the Departments of Anatomy and Cell Biology, and Psychiatry. "So what we've found is a common mechanism in the brain that can control recall of both aversive memories and memories associated with rewarding experience in the case of drug addiction."

Read in | English | Español | Français | Deutsch | Português | Italiano | 日本語 | 한국어 | 简体中文 | 繁體中文 | Nederlands | Русский | Svenska | Polski
Comments
The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
Post a new comment
Post