Radial approach for PCI leads to less bleeding and improved survival in STEMI patients

Published on January 29, 2013 at 4:39 AM · No Comments

The radial approach for percutaneous coronary interventions (PCI) was developed 20 years ago and is used for more than 50% of procedures in France, Scandinavian countries, the UK, Spain and Italy. Despite the advantages of radial access some countries in Europe such as Germany use radial access for fewer than 10% of PCI.

Evidence has accumulated in the literature showing the benefits of radial over femoral access for PCI including reduced bleeding and improved survival. In addition, the development of smaller and thinner devices has made the radial approach increasingly practical.

The European Association of Percutaneous Cardiovascular Interventions (EAPCI), the Acute Cardiovascular Care Association (ACCA)1 and the Working Group (WG) on Thrombosis of the European Society of Cardiology (ESC) therefore decided it was time to write a consensus document outlining the advantages, disadvantages and expertise requirements of the radial approach. The paper is published today in EuroIntervention, online ahead of print.2

Patients receiving an acute intervention, for example in myocardial infarction, need anticoagulants and antiplatelet drugs but these increase the risk of bleeding. Meta-analyses of randomised studies and large observational registries show that radial access reduces procedure access site-related major bleeding compared to femoral access. In addition, patients receiving the femoral approach must lie down for several hours after PCI to reduce the risk of severe bleeding while radial access allows patients to stand up in one hour.

Dr Marco Tubaro (Italy), ACCA member and co-author, said: "The radial approach strongly reduces the bleeding complication at the site of the procedure. The reduction in bleeding translates into a reduction in events and even into a reduction in mortality, particularly in patients with ST-elevation myocardial infarction (STEMI)."

Professor Kurt Huber (Austria), a representative of both the WG on Thrombosis and ACCA, said: "There's a lot of knowledge now that radial access is relatively safe, it's easier for the patient, there are fewer bleeding complications, and most acute interventions can be performed through the radial artery because we have smaller and thinner devices. This was not the case some years ago."

He added: "In a small percentage of patients the radial approach does not work, for example if the arteries in the arm are too small, if rare anatomical situations hinder the radial approach or if specific interventional strategies are necessary. So interventionalists should also know the femoral approach. The more experience interventionalists have with radial, the less they are forced to switch to femoral."

The consensus document emphasises the importance of maintaining expertise in both techniques. The authors state: "Proficiency in the femoral approach is required because it may be needed as a bailout strategy or when large guiding catheters are required."

Professor Martial Hamon (France), first author of the paper, said: "Overall I think there is a consensus now that the radial arteries can be used as the default access site for PCI. However we need to be aware of remaining concerns, for example risk of stroke and radiation exposure, especially during the learning curve. There also remains the issue of non-access site bleeding whatever the access site used. These issues are outlined in the paper."

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