The Agency for Science, Technology and Research (A*STAR)'s Experimental Therapeutics Centre (ETC), a center of excellence to advance and accelerate drug discovery in Singapore, and Debiopharm Group™ (Debiopharm), the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology as well as companion diagnostics, today announced the signature of an exclusive research collaboration to develop oral small molecules targeting new class of epigenetic modulators.
Under the terms of the agreement, Debiopharm and ETC will co-finance the discovery phase of the project, whilst Debiopharm will be in charge of development.
"This partnership aims to target tumors with genetic lesions. The use of epigenetic targets is emerging as an effective and valuable approach for personalized medicine strategies for cancer treatment," said Andres McAllister, Chief Scientific Officer Research & Evaluation, Debiopharm International SA, "ETC represents the perfect partner to develop this project as they are experts in the field of oncology and possess the full range of drug discovery capabilities. Their situation within the Biopolis campus is a major asset for the development of new products."
ETC is directed by Prof. Alex Matter who has a highly successful track record within the pharmaceutical industry. He was the Global Head of Oncology Research for Novartis Pharmaceuticals Corporation and he played an important role in the success of several anticancer drugs, including Gleevec/Glivec® and more recently, Tasigna®.