Study investigates associations between self-rated physical fitness and dementia risk

Published on February 26, 2014 at 6:07 AM · No Comments

How would you rate your own physical fitness? Is it good, satisfactory or maybe even poor? Surprisingly, your answer may reveal your future risk of getting dementia.

A recent collaborative study from Finland, involving the follow-up of 3,559 adults for 30 years, has found that a simple question about self-rated physical fitness in midlife may reveal individuals who are at an increased risk of developing dementia. Those who reported poor self-rated physical fitness in midlife, at the mean age of 50 years, were four times more likely to get dementia during the next three decades compared to those with good self-rated physical fitness.

"Previous research has shown that self-rated health is a strong indicator of adverse health events. This is the first large population-based study investigating associations between self-rated physical fitness during the three decades from midlife to later life and dementia risk," says Postdoctoral Researcher, Dr Jenni Kulmala from the Gerontology Research Center at the University of Jyväskylä, Finland.

The association between poor self-rated physical fitness and dementia was most pronounced among noncarriers of the apolipoprotein E ε4 allele, that is, people who did not have a strong genetic susceptibility for dementia. A strong association was also observed among people with chronic diseases.

"Chronic conditions independently increase the dementia risk. Furthermore, if a person additionally feels that his or her physical fitness is poor, the risk is even higher. In terms of dementia prevention, maintaining good physical fitness seems to be especially important for people with chronic diseases," Kulmala says.

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