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Diabetes is a disorder of metabolism—the way the body uses digested food for growth and energy. Most of the food people eat is broken down into glucose, the form of sugar in the blood. Glucose is the main source of fuel for the body.

After digestion, glucose passes into the bloodstream, where it is used by cells for growth and energy. For glucose to get into cells, insulin must be present. Insulin is a hormone produced by the pancreas, a large gland behind the stomach.

When people eat, the pancreas automatically produces the right amount of insulin to move glucose from blood into the cells. In people with diabetes, however, the pancreas either produces little or no insulin, or the cells do not respond appropriately to the insulin that is produced. Glucose builds up in the blood, overflows into the urine, and passes out of the body in the urine. Thus, the body loses its main source of fuel even though the blood contains large amounts of glucose.
Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans. A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington's disease. [More]
New York Blue Light Symposium highlights three measures to counter consequences of artificial illumination

New York Blue Light Symposium highlights three measures to counter consequences of artificial illumination

The New York Blue Light Symposium convened in New York from June 26-27, 2015. The event was sponsored by the International Blue Light Society (Senior Representative: Kazuo Tsubota), which was founded to research and release findings on the effects of blue light on the human body. [More]
Researchers compare relationship between marital status and body mass index in nine European countries

Researchers compare relationship between marital status and body mass index in nine European countries

It is generally assumed that marriage has a positive influence on health and life expectancy. But does this "marriage bonus" also apply to the health indicator of body weight? Researchers at the University of Basel and the Max Planck Institute for Human Development have investigated this question in cooperation with the market research institute GfK. Specifically, they compared the body mass index of married couples with that of singles in nine European countries. [More]
New discovery could lead to personalized treatment for colon cancer

New discovery could lead to personalized treatment for colon cancer

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer. [More]
Exhausted army of immune cells may damage the very body they are supposed to protect

Exhausted army of immune cells may damage the very body they are supposed to protect

An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge. [More]
Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

A new study reveals that drinking low-calorie cranberry juice cocktail may help lower the risk of chronic diseases that rank among the leading causes of death worldwide, including heart disease, diabetes and stroke. The finding is welcome news considering the World Health Organization estimates the trio of diseases annually claim 15.6 million lives around the globe. [More]
Neighborhood physical and social environments may affect type 2 diabetes risk

Neighborhood physical and social environments may affect type 2 diabetes risk

Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine. [More]
Researchers discover mechanism that regulates metabolism

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ. [More]
New 3-step solution could help parents banish their children's fussy eating habits

New 3-step solution could help parents banish their children's fussy eating habits

Parents could banish their children's fussy eating habits by following three simple steps, a new study suggests. Introducing the 'three Rs' - Repetition, Role Modelling and Rewards - at meal times could help parents to get their children to eat, and even like, new vegetables, according to new research from Aston and Loughborough Universities. [More]
New survey sheds light on the way Americans think about their brain health, lifestyle habits

New survey sheds light on the way Americans think about their brain health, lifestyle habits

Is your brain important to you? Do you know how to keep it healthy? According to a recent survey conducted by Reader’s Digest in partnership with the Alzheimer’s Association, 91 percent of people believe they can reduce their risk of cognitive decline, but they have misconceptions about ways to keep their brains healthy. [More]
Elsevier announces highlights of 2014 Impact Factor performance

Elsevier announces highlights of 2014 Impact Factor performance

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the highlights of its journal Impact Factor performance in 2014. According to the 2014 Journal Citation Reports (JCR) published by Thomson Reuters, Elsevier saw 55% of its journal Impact Factors increase from 2013 to 2014, ahead of the aggregate across other journals. [More]
Spinifex Pharmaceuticals enters into agreement to be acquired by Novartis

Spinifex Pharmaceuticals enters into agreement to be acquired by Novartis

Spinifex Pharmaceuticals, Inc., a company focused on the development of new drugs for the treatment of chronic pain, today announces that it has agreed to the sale of Spinifex to Novartis International AG, for an upfront cash consideration of US$200 million plus undisclosed clinical development and regulatory milestone payments. [More]
New research reveals that polluted Toronto neighbourhoods have high rates of childhood asthma

New research reveals that polluted Toronto neighbourhoods have high rates of childhood asthma

Children who develop asthma in Toronto are more likely to have been born in a neighbourhood that has a high level of traffic-related air pollution, new research suggests. [More]
Health Canada informs Canadians that eight unauthorized health products were seized from Better Bodies Supplements

Health Canada informs Canadians that eight unauthorized health products were seized from Better Bodies Supplements

Health Canada is informing Canadians that eight unauthorized health products (listed in the table below) were seized from Better Bodies Supplements, 118 Main Street North, in Airdrie, Alta. [More]
Texas Biomed, Take Off Pounds Sensibly establish new TOPS Nutrition and Obesity Research Center

Texas Biomed, Take Off Pounds Sensibly establish new TOPS Nutrition and Obesity Research Center

Texas Biomedical Research Institute and Wisconsin-based non-profit Take Off Pounds Sensibly are establishing the new TOPS® Nutrition and Obesity Research Center with the goal of conducting research into the causes, health risks and treatment of human obesity. Studies at the Center will focus on the role of genetic predisposition to metabolic changes, nutritional preferences, appetite regulation, food intake and choice and incidence of obesity-related illnesses. [More]
Study: High blood pressure linked to lower risk for Alzheimer's disease

Study: High blood pressure linked to lower risk for Alzheimer's disease

A new study suggests that people with a genetic predisposition to high blood pressure have a lower risk for Alzheimer's disease. [More]
University of Leicester collaborates with Youth Sport Trust to make adolescent girls stay active

University of Leicester collaborates with Youth Sport Trust to make adolescent girls stay active

Researchers from the University of Leicester are working with the Youth Sport Trust to determine whether a school-based physical activity programme could help provide the key to encouraging adolescent girls to be active and stay active. [More]
New strategies may help clinicians and hospitals better manage patients with chronic conditions

New strategies may help clinicians and hospitals better manage patients with chronic conditions

Experts have identified strategies for using electronic health records to improve care for patients with chronic kidney disease. The guidance, which will appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies. [More]
DaVita's HealthCare Partners division celebrates National Men's Health Month

DaVita's HealthCare Partners division celebrates National Men's Health Month

HealthCare Partners, a division of DaVita HealthCare Partners Inc., celebrates the month of June – National Men's Health Month – by recognizing the importance of bringing awareness to the health care issues that affect men. [More]

Experts identify new strategies for using EHRs to treat chronic kidney disease patients

Experts have identified new strategies for using electronic health records (EHRs) to treat patients with chronic kidney disease. These recommendations may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies. [More]
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