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Diabetes is a disorder of metabolism—the way the body uses digested food for growth and energy. Most of the food people eat is broken down into glucose, the form of sugar in the blood. Glucose is the main source of fuel for the body.

After digestion, glucose passes into the bloodstream, where it is used by cells for growth and energy. For glucose to get into cells, insulin must be present. Insulin is a hormone produced by the pancreas, a large gland behind the stomach.

When people eat, the pancreas automatically produces the right amount of insulin to move glucose from blood into the cells. In people with diabetes, however, the pancreas either produces little or no insulin, or the cells do not respond appropriately to the insulin that is produced. Glucose builds up in the blood, overflows into the urine, and passes out of the body in the urine. Thus, the body loses its main source of fuel even though the blood contains large amounts of glucose.
Research finding points to potential new treatment for metabolic disorders

Research finding points to potential new treatment for metabolic disorders

Researchers at the University of Michigan have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders. [More]
NIH study finds limited kidney benefit from more rigorous blood pressure treatment

NIH study finds limited kidney benefit from more rigorous blood pressure treatment

Using two drugs was no more effective than a single drug in slowing disease progression in people with autosomal dominant polycystic kidney disease (ADPKD), according to two studies funded by the National Institutes of Health. One of the studies also showed that rigorous blood pressure treatment slowed growth of kidney cysts, a marker of ADPKD, but had little effect on kidney function compared to standard blood pressure treatment. [More]
EKF Diagnostics and Joslin Diabetes Center enter collaborative relationship

EKF Diagnostics and Joslin Diabetes Center enter collaborative relationship

EKF Diagnostics, the global diagnostics company, has entered a multi-year, collaborative relationship with Joslin Diabetes Center (“Joslin”) in support of the ongoing clinical and commercial translation of TNFR1 & 2 biomarkers. These novel biomarkers can help identify patients with Type 1 and Type 2 diabetes that are at an increased risk of developing end stage renal disease (ESRD), up to ten years in advance. [More]
Social robots help diabetic children to become more confident about their futures

Social robots help diabetic children to become more confident about their futures

Social robots are helping diabetic children accept the nature of their condition and become more confident about their futures, scientists have announced following a four-and-a-half year research study. [More]
Chemical compound in coffee may help prevent damaging effects of obesity

Chemical compound in coffee may help prevent damaging effects of obesity

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. [More]
Plymouth researchers receive 2014 Oral and Dental Research Trust-GSK Research Award

Plymouth researchers receive 2014 Oral and Dental Research Trust-GSK Research Award

Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry have received one of the prestigious 2014 Oral and Dental Research Trust-GSK Research Awards from the British Society of Oral and Dental Research, for a research project which seeks to re-programme the immune system to stop bone destruction and tooth loss in severe gum disease. [More]
Solgar voluntarily recalls ABC Dophilus Powder

Solgar voluntarily recalls ABC Dophilus Powder

Solgar, Inc., of Leonia, NJ, is voluntarily recalling ABC Dophilus Powder. The recall was initiated, out of an abundance of caution, because the product was found to contain Rhizopus oryzae, which may cause Mucormycosis. [More]
A single gene mutation can halve the risk of heart disease

A single gene mutation can halve the risk of heart disease

Recent research has shown that inactivation of a single gene reduces the risk of heart attack by 50%. [More]
Exposure to tobacco smoke, roadway air pollution can contribute to obesity

Exposure to tobacco smoke, roadway air pollution can contribute to obesity

New research from Keck Medicine of the University of Southern California (USC) bolsters evidence that exposure to tobacco smoke and near-roadway air pollution contributes to the development of obesity. [More]
Sleep disorders increase risk of motor vehicle accidents, poor health status among firefighters

Sleep disorders increase risk of motor vehicle accidents, poor health status among firefighters

Sleep disorders are independent risk factors for heart attacks and motor vehicle crashes, which are the two leading causes of death for firefighters in the United States. [More]
Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

A study led by Massachusetts General Hospital (MGH) investigators has identified what appears to be a molecular switch controlling inflammatory processes involved in conditions ranging from muscle atrophy to Alzheimer's disease. [More]
Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions. [More]
Concordia Healthcare reports record revenues of 147% in third quarter 2014

Concordia Healthcare reports record revenues of 147% in third quarter 2014

Concordia Healthcare Corp. ("Concordia" or the "Company"), a diverse healthcare company focused on legacy pharmaceutical products, orphan drugs, and medical devices for the diabetic population, today announced its financial and operational results for the three and nine months ended September 30, 2014. [More]
AADE offers self-care tips for people with diabetes

AADE offers self-care tips for people with diabetes

From Thanksgiving through New Year's Day, the holidays can be fun and heartwarming. They can also be exhausting and stressful. [More]
Eye screenings of underserved populations reveal one in five has early stage diabetic retinopathy

Eye screenings of underserved populations reveal one in five has early stage diabetic retinopathy

Eye screenings of people with diabetes in underserved communities revealed that one in five had early stage diabetic retinopathy, according to a new study by a research consortium including investigators at the University of Alabama at Birmingham. [More]
Scientists receive NARSAD Distinguished Investigator Grants for mental health research

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

The Brain & Behavior Research Foundation today announced the award of NARSAD Distinguished Investigator Grants valued at $1.5 million to 15 scientists, who are full professors or the equivalent, conducting innovative projects in diverse areas of neurobiological and behavioral research. [More]
Metabolic syndrome screening in bipolar disorder warranted

Metabolic syndrome screening in bipolar disorder warranted

The frequency of the metabolic syndrome in patients with bipolar disorder warrants systematic screening, say researchers, particularly among men, older patients and those receiving atypical antipsychotic treatment. [More]
Study: Fast-food outlets in inner city neighborhoods linked to risk of diabetes, obesity

Study: Fast-food outlets in inner city neighborhoods linked to risk of diabetes, obesity

How close you are to fast-food outlets may be linked to your risk of Type-2 diabetes and obesity a new study led by the University of Leicester has discovered. [More]
Studies evaluate traditional management of heart attack patients after discharge from hospital

Studies evaluate traditional management of heart attack patients after discharge from hospital

Beta-blockers have been a cornerstone in the treatment of heart attack survivors for more than a quarter of a century. However, many of the data predate contemporary medical therapy such as reperfusion, statins, and antiplatelet agents, and recent data have called the role of beta-blockers into question. [More]
Study examines overall survival of patients with chronic HCV infection, cirrhosis

Study examines overall survival of patients with chronic HCV infection, cirrhosis

Patients with chronic hepatitis C virus infection and advanced fibrosis or cirrhosis who attained sustained virological response (SVR) had survival comparable with that of the general population, whereas patients who did not attain SVR had reduced survival, according to a study in the November 12 issue of JAMA. [More]