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Diabetes is a disorder of metabolism—the way the body uses digested food for growth and energy. Most of the food people eat is broken down into glucose, the form of sugar in the blood. Glucose is the main source of fuel for the body.

After digestion, glucose passes into the bloodstream, where it is used by cells for growth and energy. For glucose to get into cells, insulin must be present. Insulin is a hormone produced by the pancreas, a large gland behind the stomach.

When people eat, the pancreas automatically produces the right amount of insulin to move glucose from blood into the cells. In people with diabetes, however, the pancreas either produces little or no insulin, or the cells do not respond appropriately to the insulin that is produced. Glucose builds up in the blood, overflows into the urine, and passes out of the body in the urine. Thus, the body loses its main source of fuel even though the blood contains large amounts of glucose.
Viewpoints: Crediting the health law for modest premium increases; Hollywood misses the mark on sick teens

Viewpoints: Crediting the health law for modest premium increases; Hollywood misses the mark on sick teens

The rate of growth on premiums for employer-based health coverage in the first five months of this year was one of the lowest in 16 years. Despite longstanding concerns that employer-sponsored coverage might become too costly to sustain, that market seems to have stabilized for now .... Thanks to the Affordable Care Act, federal tax credit subsidies -; available for people earning up to 400 percent of the federal poverty level ($95,400 for a family of four) -; are helping to make these policies affordable and cushioning the impact of premium increases in some cities (9/14). [More]
New research shows schizophrenia comprises 8 genetically distinct disorders

New research shows schizophrenia comprises 8 genetically distinct disorders

New research shows that schizophrenia isn't a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness. [More]
Benefits of blood pressure lowering drugs for low risk patients 'still open to question'

Benefits of blood pressure lowering drugs for low risk patients 'still open to question'

Dr Stephen Martin and colleagues argue that this strategy is failing patients and wasting healthcare resources. They call for a re-examination of the threshold and urge clinicians to be cautious about treating low risk patients with blood pressure lowering drugs. [More]
GILZ protein key to preventing bone loss, researchers report

GILZ protein key to preventing bone loss, researchers report

A small protein named GILZ appears to protect against the bone loss that often accompanies arthritis and its treatment, researchers report. [More]
Health value of Apple's Watch questioned

Health value of Apple's Watch questioned

Health care professionals say there is little evidence the new watch surpasses gadgets already on the market, although more health features may be in store, Reuters reports. Meanwhile, The Associated Press examines tensions between Silicon Valley tech giants and government regulators. [More]
Researchers report that dendritic cells can affect psoriasis

Researchers report that dendritic cells can affect psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine. [More]
Study: High-dose prescribing increases by 23% in Canada

Study: High-dose prescribing increases by 23% in Canada

High-dose opioid prescribing increased by 23 per cent in Canada between 2006 and 2011, despite clinical guidelines recommending that most patients should avoid high-doses of these drugs, according to new research. [More]
ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, cosmetic and pharmaceutical industries, announced today that it has entered into an ingredient supply agreement with Healthy Directions, a direct-to-consumer nutritional supplement retailer and wholly-owned subsidiary of Helen of Troy Limited. [More]
New collaborative approach could help improve diabetes care in China

New collaborative approach could help improve diabetes care in China

Diabetes has become a major public health crisis in China, with an annual projected cost of 360 billion RMB (nearly 35 billion British pounds) by 2030, but a new collaborative approach to care that uses registries and community support could help improve diabetes care, according to a new three-part Series about diabetes in China published in The Lancet Diabetes & Endocrinology. [More]
FDA approves Contrave extended-release tablets for chronic weight management

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition. [More]
HolaDoctor launches new Interactive Health Insurance Center to educate Hispanics

HolaDoctor launches new Interactive Health Insurance Center to educate Hispanics

HolaDoctor.com, the leading health website in the Hispanic digital market, launched a new Interactive Health Insurance Center which aims to inform and educate Hispanics on how to apply for and acquire health coverage in 2015. [More]
New research shows statins could reduce common diabetes complications

New research shows statins could reduce common diabetes complications

The development of common diabetes complications that can lead to blindness and amputations could be reduced by taking statins, indicates new research published in The Lancet Diabetes & Endocrinology. [More]
Professor receives award for development of anti-angiogenic therapy for retinal disease

Professor receives award for development of anti-angiogenic therapy for retinal disease

Napoleone Ferrara, MD, distinguished professor of pathology and distinguished adjunct professor of ophthalmology at the University of California, San Diego School of Medicine and senior deputy director for basic sciences at UC San Diego Moores Cancer Center, was named today as one of seven recipients of the Ant-nio Champalimaud Vision Award in Lisbon, Portugal. [More]
Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes. [More]
Study looks at blood type and risk of cognitive impairment

Study looks at blood type and risk of cognitive impairment

People with blood type AB may be more likely to develop memory loss in later years than people with other blood types, according to a study published in the September 10, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. [More]
Food commercials 'get under the skin' of teens by activating reward regions

Food commercials 'get under the skin' of teens by activating reward regions

Children and adolescents see thousands of food commercials each year and most of them advertise junk foods high in sugar, fat and salt. [More]
Continuing to work during depressive illness may offer employees certain health benefits

Continuing to work during depressive illness may offer employees certain health benefits

The collaborative study between the University Of Melbourne and the Menzies Research Institute at the University of Tasmania is the first to estimate the long-term costs and health outcomes of depression-related absence as compared to individuals who continue to work among employees with depression in Australia. [More]
People with diabetes may have six-fold higher risk of developing heart failure

People with diabetes may have six-fold higher risk of developing heart failure

People with diabetes who appear otherwise healthy may have a six-fold higher risk of developing heart failure regardless of their cholesterol levels, new Johns Hopkins Bloomberg School of Public Health research suggests. [More]
Researchers find that people suffering from sleep apnea have weaker brain blood flow

Researchers find that people suffering from sleep apnea have weaker brain blood flow

Employing a measure rarely used in sleep apnea studies, researchers at the UCLA School of Nursing have uncovered evidence of what may be damaging the brain in people with the sleep disorder - weaker brain blood flow. [More]
Dell, Terascala and TGen to install genomic data management solution at NCI

Dell, Terascala and TGen to install genomic data management solution at NCI

Dell, Terascala and the Translational Genomics Research Institute are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute. [More]