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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
University of Adelaide-led project develops new test to eradicate H5N1 bird flu

University of Adelaide-led project develops new test to eradicate H5N1 bird flu

A University of Adelaide-led project has developed a new test that can distinguish between birds that have been vaccinated against the H5N1 strain of avian influenza virus or "bird flu" with those that have been naturally infected. [More]
Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the treatment and prevention of infectious diseases, announced today that the Department of Defense through the Medical Countermeasure Systems-Joint Vaccine Acquisition Program, a subordinate command of the Joint Program Executive Office for Chemical and Biological Defense, Edgewood, MD, has contracted the manufacture and IND-enabling preclinical testing of the Profectus trivalent Ebola/Marburg vaccine. [More]
Insufficient Th1 polarisation blocks RCC vaccine efficacy

Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study. [More]
WUSM researchers sequence genome of enterovirus D68 samples from patients

WUSM researchers sequence genome of enterovirus D68 samples from patients

Researchers at Washington University School of Medicine in St. Louis have sequenced the genome of enterovirus D68 sampled from patients treated at St. Louis Children's Hospital. Nationwide, the virus has spread rapidly in recent months and caused severe respiratory illness in young children, with some patients requiring hospitalization. [More]
NCI supports further clinical development of next-generation HPV vaccine

NCI supports further clinical development of next-generation HPV vaccine

The National Cancer Institute in the USA is supporting the new vaccine developed at the MedUni Vienna against the human papillomavirus (HPV) with at least US$ 3.5 million. This is a major success for the developers and means that the foundations can now be laid for the clinical trials needed for licensing as a vaccine. [More]
ETEC vaccine candidate provides significant protection against bacterial diarrhea

ETEC vaccine candidate provides significant protection against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. [More]
Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Imaxio, a biopharmaceutical company specialized in vaccines, today announces that it has been awarded funding of EUR 600,000 (USD 772,000) by the French National Research Agency (Agence Nationale de la Recherche, ANR) for the OPTIVAC project 'leveraging On t-cell immune resPonse To Improve influenza VACcines'. [More]
Salk Institute scientists identify promising target for HIV/AIDS treatment

Salk Institute scientists identify promising target for HIV/AIDS treatment

Like a slumbering dragon, HIV can lay dormant in a person's cells for years, evading medical treatments only to wake up and strike at a later time, quickly replicating itself and destroying the immune system. [More]
Rewriting the family history of Ebola

Rewriting the family history of Ebola

The research shows that filoviruses — a family to which Ebola and its similarly lethal relative, Marburg, belong — are at least 16-23 million years old. [More]
Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

A Virginia Tech professor is working on a vaccine that could help smokers conquer their nicotine addiction, making many smoking-related diseases and deaths relics of the 21st century. [More]
WHO holds meeting to discuss on how to fast track testing, deployment of Ebola vaccines

WHO holds meeting to discuss on how to fast track testing, deployment of Ebola vaccines

WHO convened a meeting with high-ranking government representatives from Ebola-affected countries and development partners, civil society, regulatory agencies, vaccine manufacturers and funding agencies yesterday to discuss and agree on how to fast track testing and deployment of vaccines in sufficient numbers to impact the Ebola epidemic. [More]
Human trial of second investigational Ebola vaccine candidate under way

Human trial of second investigational Ebola vaccine candidate under way

Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health's Clinical Center in Bethesda, Maryland. [More]
Helping children understand Ebola

Helping children understand Ebola

It dominates the headlines and is striking fear and panic in many communities around the world, Ebola. The constant barrage of information and so much unknown can be especially difficult for children, making it all the more important for parents to help their kids feel safe and to have a dialogue with them at the appropriate developmental level. [More]
ADI develops ELISA test kits for detection of Ebola viral protein antibodies

ADI develops ELISA test kits for detection of Ebola viral protein antibodies

San Antonio, Texas-based Biotech Company Alpha Diagnostic Int'l has developed and released several convenient, rapid, and sensitive ELISA test kits for the detection of major Ebola viral protein antibodies (Glycoprotein, GP; Nucleoprotein, NP, and Viral Protein 40 or VP40). [More]
Views on Ebola: America needs to 'calm down'; political criticism is off base

Views on Ebola: America needs to 'calm down'; political criticism is off base

A Texas university refuses to accept students from Nigeria, where there were a couple dozen Ebola cases before the disease was quickly stopped. [More]
Flu vaccines have protective effect against heart disease

Flu vaccines have protective effect against heart disease

Flu vaccines are known to have a protective effect against heart disease, reducing the risk of a heart attack. For the first time, this research, published in Vaccine, reveals the molecular mechanism that underpins this phenomenon. The scientists behind the study say it could be harnessed to prevent heart disease directly. [More]
Two IOM members honored for outstanding service

Two IOM members honored for outstanding service

The Institute of Medicine honored members Dan G. Blazer and Richard B. Johnston Jr. for their outstanding service during the IOM's 44th annual meeting in Washington, D.C. [More]
Views on Ebola: Blame misplaced; conspiracy theories abound; 'nasty' politicization

Views on Ebola: Blame misplaced; conspiracy theories abound; 'nasty' politicization

Anybody who has been following the travails of our dysfunctional health-care system can find plenty of reasons to criticize American hospitals. [More]
New study reveals how cancer becomes drug resistant over time

New study reveals how cancer becomes drug resistant over time

Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of drug-resistant cells, making cancer hard to combat. [More]
Pentagon plans 30-person team to tackle Ebola in U.S.

Pentagon plans 30-person team to tackle Ebola in U.S.

The defense department announced Sunday that it would create a team to assist U.S. doctors responding to new Ebola cases, while the government issued more stringent guidelines for protective garb for health care workers treating Ebola patients. In addition, The Wall Street Journal profiles a biologist who has been working since 1997 on an Ebola vaccine which has been proven to block the disease in monkeys. [More]