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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity. [More]
UC Davis researchers develop Hepatitis virus-like particles to target breast cancer

UC Davis researchers develop Hepatitis virus-like particles to target breast cancer

UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research. [More]
Research: Adenosine deaminase may help activate immune system against HIV

Research: Adenosine deaminase may help activate immune system against HIV

New research findings published in the February 2016 issue of the Journal of Leukocyte Biology, suggest that a new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug. [More]
Immunological changes during pregnancy may influence response to influenza vaccination

Immunological changes during pregnancy may influence response to influenza vaccination

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers will present findings from a study titled, T-follicular helper (Thf) cell expansion varies by trimester after influenza vaccination in pregnancy. [More]
Study provides new insights into breast cancer metastasis

Study provides new insights into breast cancer metastasis

It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs. [More]
Study shows several Envigo rat models susceptible to genital HSV-2 infection

Study shows several Envigo rat models susceptible to genital HSV-2 infection

A scientific collaboration between Envigo and the Department of Infectious Disease at the University of Gothenburg, Sweden has unveiled study findings into rat models and their susceptibility to intra-vaginal herpes simplex virus-2 (HSV-2) infection. [More]
Rockland announces availability of new human melanoma cell lines

Rockland announces availability of new human melanoma cell lines

Rockland Immunochemicals, Inc. announces the availability of a new collection of human melanoma cell lines that have been developed and characterized over several decades in the laboratory of Meenhard Herlyn, D.V.M., D.Sc., Caspar Wistar Professor in Melanoma Research, Director of the Melanoma Research Center, and professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute in Philadelphia. [More]
MabVax receives FDA authorization to initiate 89Zr-HuMab-5B1 Phase I trial in pancreatic cancer patients

MabVax receives FDA authorization to initiate 89Zr-HuMab-5B1 Phase I trial in pancreatic cancer patients

MabVax Therapeutics Holdings, Inc., a clinical-stage oncology drug-development company, announces receipt of notice from the U.S. Food and Drug Administration authorizing initiation of a Phase I clinical trial with 89Zr-HuMab-5B1 as a new generation PET scan cancer imaging agent in patients with pancreatic cancer. [More]
UI researchers remind US doctors to watch for two diseases that could be passed from mother to child

UI researchers remind US doctors to watch for two diseases that could be passed from mother to child

While world health leaders race to contain the spread of the mosquito-borne Zika virus in the Americas, researchers at the University of Iowa are reminding doctors in the United States to be on the lookout for two other vector-borne and potentially life-threatening diseases that can be passed from mother to child through the placenta. [More]
Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Leaders of several cancer centers designated by the National Cancer Institute have united to support human papillomavirus vaccination. Among them is Cheryl Willman, MD, Director and CEO of the University of New Mexico Comprehensive Cancer Center. [More]
Meningitis Now urges schools to protect pupils from deadly meningitis

Meningitis Now urges schools to protect pupils from deadly meningitis

LEADING UK meningitis charity, Meningitis Now, is calling on headteachers to ensure pupils are protected from deadly meningitis. [More]
AVAX announces results of Phase 1/2 OVAX study in patients with advanced ovarian cancer

AVAX announces results of Phase 1/2 OVAX study in patients with advanced ovarian cancer

AVAX Technologies, Inc., a pioneer in personalized cancer vaccines, today announced the results of its Phase 1/2 OVAX study in patients with platinum resistant relapsed Stage III or IV Ovarian Cancer. [More]
Scientists demonstrate effectiveness of ART in HIV-infected infants

Scientists demonstrate effectiveness of ART in HIV-infected infants

Recent clinical trials conducted in South Africa have established that babies born with HIV should be treated with antiretroviral therapy (ART) as early as possible, since earlier treatment significantly decreases their mortality and morbidity rates. [More]
Facts associated with Zika virus

Facts associated with Zika virus

As the Zika virus captures headlines across the United States, with its possible link to birth defects and the first cases reported in the U.S. (all traced back to overseas travel), it's an opportune time to review the facts associated with this disease. [More]
A Thai man with Zika virus has been hospitalized in Taiwan

A Thai man with Zika virus has been hospitalized in Taiwan

A man from Thailand has been hospitalized in Taiwan after having arrived there infected with Zika virus, an agent thought to be associated with brain-damaging birth defects in infants. [More]
Immunotherapy could be the future of cancer treatments

Immunotherapy could be the future of cancer treatments

For decades most cancers have been treated with the standard of care treatments which typically include surgery, radiation and/or chemotherapy. Now there is talk that immunotherapy represents "the future of cancer treatments." [More]
UM SOM study leads to FDA approval of Neulasta drug for treatment of radiation injury

UM SOM study leads to FDA approval of Neulasta drug for treatment of radiation injury

As a result of research performed by scientists at the University of Maryland School of Medicine, the U.S. Food and Drug Administration has approved the use of a drug to treat the deleterious effects of radiation exposure following a nuclear incident. The drug, Neulasta, is one of a very small number that have been approved for the treatment of acute radiation injury. [More]
CSU's BioMARC awarded DoD contract to help develop new vaccines to combat encephalitic viruses

CSU's BioMARC awarded DoD contract to help develop new vaccines to combat encephalitic viruses

Colorado State University's Biopharmaceutical Manufacturing and Academic Resource Center has been awarded a 10-month, $4.6 million contract funded by the Department of Defense to help develop and manufacture new vaccines to fight encephalitic viruses that cause inflammation of the brain. [More]
MU School of Medicine researchers find link between varicella zoster virus vaccine and corneal inflammation

MU School of Medicine researchers find link between varicella zoster virus vaccine and corneal inflammation

In use for more than 20 years, the varicella zoster virus vaccine for chickenpox and shingles is considered an essential medicine by the World Health Organization. However, researchers from the University of Missouri School of Medicine have found, in rare instances, a link between the vaccine and corneal inflammation. [More]
Study outlines new model to help predict age-related response to hepatitis B vaccine

Study outlines new model to help predict age-related response to hepatitis B vaccine

Physicians have known for years that patients respond differently to vaccines as they age. There may soon be a new way to predict and enhance the effectiveness of vaccinations, in particular the hepatitis B vaccine. [More]
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