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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
Duke-NUS study highlights Zika virus structure and behaviour

Duke-NUS study highlights Zika virus structure and behaviour

An important breakthrough in understanding the Zika virus structure and its behaviour has been highlighted in a study by Duke-NUS Medical School scientists. [More]
Penn researchers report results of CAR therapy trial in brain cancer patients

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016. [More]
Researchers reveal how relatively unknown pathogen led to current Zika outbreak

Researchers reveal how relatively unknown pathogen led to current Zika outbreak

An analysis comparing the individual differences between over 40 strains of Zika virus (30 isolated from humans, 10 from mosquitoes, and 1 from monkeys) has identified significant changes in both amino acid and nucleotide sequences during the past half-century. [More]
African sleeping sickness parasite has defence mechanism against potential pharmaceuticals

African sleeping sickness parasite has defence mechanism against potential pharmaceuticals

Researchers from Umea University in Sweden have discovered that the single-celled parasite causing African sleeping sickness has a defence mechanism against potential pharmaceuticals under development against the disease. The deadly parasite has an enzyme that can cleave and hence disarm adenosine analogue pharmaceuticals. This according to a study recently published in the Journal of Biological Chemistry. [More]
Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

Falling asleep and waking up are key transitions in everyone's day. Millions of people have trouble with these transitions - they find it hard to fall asleep or stay asleep at night, and hard to stay awake during the day. Despite decades of research, how these transitions work - the neurobiological mechanics of our circadian rhythm - has remained largely a mystery to brain scientists. [More]
Funding improves for maternal, child health compared to donor investments in HIV, TB and malaria

Funding improves for maternal, child health compared to donor investments in HIV, TB and malaria

Funding earmarked for improving maternal and child health in low- and middle-income countries has grown faster since 2010 than funding for HIV, TB, and malaria. [More]
Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

The emerging Zika virus epidemic is bringing to light a longstanding ethical challenge in medical research: the inclusion of pregnant women. With new funding from the Wellcome Trust, an interdisciplinary team of scholars will focus on issues of ethics and research in pregnancy and women of reproductive age, beginning with the current Zika context and later expanding to general public health research. [More]
International scientists discuss new treatments for non small cell lung cancer

International scientists discuss new treatments for non small cell lung cancer

More than 30 prominent international scientists gathered to discuss the state-of-the-art, as well as promising future approaches for the treatment of lung cancer at the stunning 17th century Borgo San Luigi, in Monteriggion, in the heart of the Tuscany countryside. [More]
Prime boost approach can increase possibility of combined HCV and HIV vaccination

Prime boost approach can increase possibility of combined HCV and HIV vaccination

A combined vaccination against Hepatitis C virus (HCV) and HIV moved a step closer, with the results of a study presented at The International Liver Congress 2016 in Barcelona, Spain today. [More]
Cary Institute gets $5 million grant to support study on Lyme disease reduction

Cary Institute gets $5 million grant to support study on Lyme disease reduction

The Steven & Alexandra Cohen Foundation has awarded a $5 million dollar leadership grant to the Cary Institute of Ecosystem Studies to support a scientific study, being done in partnership with Bard College, that seeks to reduce Lyme disease in neighborhoods. [More]
New biomarker discovery could improve chances of developing effective TB vaccine

New biomarker discovery could improve chances of developing effective TB vaccine

A team of scientists led by Oxford University have made a discovery that could improve our chances of developing an effective vaccine against Tuberculosis. [More]
Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

Mymetics Corporation, a pioneer in the research and development of virosome-based vaccines to prevent transmission of human infectious diseases across mucosal membranes, announced today that its innovative HIV vaccine candidate has shown to generate significant protection in groups of twelve female monkeys against repeated AIDS virus exposures during part of the preclinical study. [More]
HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant. [More]
New immune-suppressing therapy leads to longer survival for cross-species heart transplant

New immune-suppressing therapy leads to longer survival for cross-species heart transplant

A new immune-suppressing therapy has led to the longest survival yet for a cross-species heart transplant, according to new research conducted in part by researchers at the University of Maryland School of Medicine. [More]
Structure-based approach could lead to effective HIV vaccine

Structure-based approach could lead to effective HIV vaccine

It's been known for some time that the immune system can produce antibodies capable of "neutralizing" HIV, and stopping the AIDS-causing virus dead in its tracks. [More]
Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

A research team at Washington University School of Medicine in St. Louis has established a mouse model for testing of vaccines and therapeutics to battle Zika virus. [More]
First-ever immature antibody found in immune molecules may help combat HIV

First-ever immature antibody found in immune molecules may help combat HIV

Scientists at The Scripps Research Institute and collaborating institutions have described the first-ever immature or “teenage” antibody found in a powerful class of immune molecules effective against HIV. [More]
Aged tumor cells in melanoma behave in a different way than younger tumor cells

Aged tumor cells in melanoma behave in a different way than younger tumor cells

Cancer risk increases with one's age as accumulated damage to our cells and chronic inflammation occur over time. Now, an international team of scientists led by The Wistar Institute have shown that aged tumor cells in melanoma behave differently than younger tumor cells, according to study results published in the journal Nature. [More]
Oral Salmonella-based vaccine could prevent Type 1 diabetes

Oral Salmonella-based vaccine could prevent Type 1 diabetes

A combined vaccine therapy including live Salmonella is a safe and effective way to prevent diabetes in mice and may point to future human therapies, a new study finds. The results will be on Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston. [More]
Researchers develop novel vaccine strategy to protect against Chikungunya virus

Researchers develop novel vaccine strategy to protect against Chikungunya virus

The Chikungunya virus (CHIKV) is transmitted through mosquitoes and causes fever and joint pain that can sometimes become severe and disabling. Outbreaks of the virus have already occurred in Africa, Asia, and Europe, and in late 2013, the virus was first seen in the Americas with the number of cases dramatically increased. No vaccine to prevent or treat this virus currently exists. [More]
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