The CHAIT initiative is a public-private partnership focusing on the development of novel immunological therapeutic interventions to achieve a 'functional HIV cure' with the ultimate goal of HIV eradication. The objectives of CHAIT include: 1) to develop novel immunological approaches targeting latent HIV reservoirs; 2) to establish a leading translational program accelerating the development from bench research to clinical development; 3) to establish a robust immunological and virological monitoring platform; and 4) to engage effective dialogues with regulatory agencies to define new criteria for response to therapy. CHAIT's major strength is that it builds upon a public-private multidisciplinary partnership and leverages expertise from both academia and industry.
"CHAIT is aligned with the 'Towards an HIV Cure' scientific strategy of the International AIDS Society, the aim of which is to contribute to the establishment of an international research agenda and/or to stimulate new initiatives towards an HIV cure," said Prof Giuseppe Pantaleo (SVRI, Switzerland) who, with Prof Yves Levy (VRI, France), started this initiative. "The public-private partnership and the expertise of its members provides CHAIT with the opportunity to facilitate the clinical development of combined immunological therapeutic interventions to complement antiretroviral drugs."