Experimental TB vaccine does not protect infants, study shows

Published on February 6, 2013 at 5:06 AM · No Comments

"Hopes that a much needed new tuberculosis [TB] vaccine was on the way, the first for 90 years, have been dashed by trial results showing it did not protect babies against the disease," the Guardian reports (Boseley, 2/4). "The vaccine, known as MVA85A, is the most advanced of more than a dozen TB vaccines now in clinical trials in people, and scientists are poring over the results to learn why the trial failed and how the results can inform future studies," Reuters writes (Steenhuysen, 2/4). "The study, reported online by the Lancet on Monday, was conducted in about 2,800 South African infants," the Washington Post notes (Brown, 2/4). "They were followed for up to three years," the Associated Press writes, adding, "The vaccine's efficacy rate was about 17 percent" (2/4). "MVA85A was found to be safe and had no side effects, but 'did not provide statistically significant protection' against the TB microbe, the researchers announced," according to Agence France-Presse (2/4).

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