In the first study of its kind, lay health workers increased screening rates for hepatitis B virus (HBV) and knowledge about the disease among a group of Asian Americans, known as the Hmong, UC Davis researchers have found. The study appears online today in Cancer Epidemiology, Biomarkers & Prevention.
Hmong Americans, who originate from the mountainous areas of Laos, are at elevated risk for chronic hepatitis B - the major risk factor for liver cancer. They're also at greater risk than either white or other Asian Americans for poor outcomes from liver cancer.
Although Hmong Americans often have health insurance, cultural and language barriers can prevent access to adequate screening for hepatitis B and liver cancer, according to study author Moon Chen Jr., professor and associate director for cancer control at UC Davis, who led the research effort.
"Compared to other Asian Americans, liver cancer tends to be found at a later stage among the Hmong, and the survival rate is very low. While the overall survival rate for liver cancer is 10 percent, Hmong people who are diagnosed with the disease usually live for less than a year, and often for as little as a month or two," said Chen.
"We wanted to decrease the probability of earlier death from liver cancer among the Hmong and increase the probability of earlier detection," said Chen, who is also principal investigator for the Asian American Network for Cancer Awareness Research and Training (AANCART), the National Cancer Institute's National Center for Reducing Asian American Cancer Health Disparities.
In the study, 260 Hmong residents of Sacramento were randomly assigned to two groups. One group received home-based health education about hepatitis B and liver cancer during two visits from workers fluent in Hmong and knowledgeable about the Hmong culture. A second group learned about healthy nutrition and physical activity. The lay health-care workers also assessed participants' knowledge of hepatitis B and liver cancer during their first home visit.
Six months later, study leaders followed up to determine how many participants got HBV screenings and to assess their HBV knowledge.Twenty-four percent of Hmong subjects who learned about hepatitis B and liver cancer were later screened for HBV compared to only 10 percent of those who learned about healthy nutrition and physical activity. Hmong subjects who learned about hepatitis B and liver cancer also were more likely to show significantly greater knowledge about HBV than the control group.
Chronic hepatitis B is endemic in Asia, parts of Africa and Alaska, according to the U.S. Centers for Disease Control and Prevention. However, the concept of an infectious disease such as hepatitis B is foreign to the Hmong, since there are few terms in their language for biological agents that are not visible to the naked eye. Limited English proficiency and lack of familiarity and confidence in the American health-care system also make it more difficult for the Hmong to receive recommended screenings and timely diagnoses for diseases such as liver cancer, according to Chen.