The DiMelli (Diabetes Mellitus Incidence Cohort Registry) study examines the frequency and characteristics of diabetes phenotypes in children and young adults below the age of 20. The study was commissioned to investigate the increasing incidence of diabetes mellitus, particularly in childhood and early adulthood. The project is funded by the German Center for Diabetes Research (DZD). Bioprobe measurements were performed centrally by the Central Medical Laboratory (LMZ) at the Helmholtz Zentrum M-nchen (HMGU) so as to guarantee the high quality and comparability of laboratory parameters. The study is based on the DiMelli Bavarian Diabetes Register, the only register of its kind in Germany, which collects data on biological parameters in the blood of newly diagnosed diabetics as well as their phenotypic characteristics, i.e. their physical symptoms and features. A questionnaire is used to identify the characteristics of the form of the disease occurring in the patient in question such as body weight and weight changes as well as blood sugar levels, residual insulin production and other biomarkers.
The team of scientists headed by Professor Anette-Gabriele Ziegler, Dr. Katharina Warncke and Dr. Andreas Beyerlein from the Institute of Diabetes Research (IDF) at the Helmholtz Zentrum M-nchen, the Diabetes Research Group at the Technical University of Munich (TUM), the Children's Hospital in Munich-Schwabing and the Department of Pediatrics at the Klinikum rechts der Isar, Technical University of Munich, have now evaluated the initial data from the DiMelli study.