Non-coding RNAs linked to cancer and cancer survival

Published on February 21, 2014 at 8:53 AM · No Comments

"These molecules' existence can also be used to classify cancer patients into subgroups of individuals with different survival outcomes," adds Jones. "While the precise reason why a tumour would change the behaviour of genes in this way is not known, it is likely that it represents a mechanism by which the cancer can subvert and takeover the normally well controlled activity of our genes."

This study uncovered non-coding RNAs' cancerous role by using high-throughput sequencing techniques to analyse reams of genetic information on normal and diseased tissue as part of the Cancer Genome Atlas project.

The Cancer Genome Atlas is an ambitious project to characterize the genetic material of more than 500 tumours from more than 20 different cancers. The project provides a goldmine of data for bioinformaticians such as Jones.

Source: Simon Fraser University

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