We all carry the Apo E gene. It plays a key role in the development of Alzheimer's Disease and heart disease, along with a host of chronic ailments.
And it is greatly affected by diet.
In her seminal book, The Apo E Gene Diet: A Breakthrough in Changing, Cholesterol, Weight, Heart and Alzheimer's Using the Body's Own Genes (Elite, Hardcover, $27.95, November 1, 2007), Pamela McDonald, RNFA, FNP, an integrative healthcare professional for 28 years, has developed specific diets that support an individual's Apo E genotype.
The Apo E Gene Diet accomplishes what one-size-fits-all diets like Atkins and South Beach can never do: it prescribes the optimal combination of proteins, carbohydrates and fates for specific genotypes. The six Apo E genotypes -- Apo E 2/2, 2/3, 3/3, 4/2, 4/3, 4/4 -- responds differently to these big three macronutrients.
- Apo E type 2/2: high risk for heart disease and vascular dementia
- Apo E type 2/3: high risk for heart disease and vascular dementia
- Apo E type 3/3 (the most common genotype): high risk for metabolic disease and 20% chance of Alzheimer's
- Apo E type 4/2: greater risk for high cholesterol and 50% chance of Alzheimer's
- Apo E type 4/3: increased risk for high cholesterol and 60% chance of Alzheimer's
- Apo E type 4/4: 92% chance of Alzheimer's
As Larry Dossey, MD, bestselling author of The Extraordinary Healing Power of Ordinary Things, writes, "This book represents the future of medicine -- an individualized, personalized approach that honors our genetic uniqueness."