Regurin(R) XL (trospium chloride), a once-daily, prolonged-release capsule to treat patients with overactive bladder (OAB) has been launched in the UK. Regurin(R) XL provides rapid, significant and consistent improvements in the symptoms of OAB1 and has a reduced potential for central nervous system (CNS) side effects.
OAB, also known as irritable bladder, is a condition that results from sudden, involuntary contraction of the muscle in the wall of the urinary bladder. Key symptoms of OAB include frequent urination, urgency of urination, and urge incontinence. Urinary incontinence is a distressing and often embarrassing problem estimated to affect over a third of women in the UK over 40(8).
By rapidly, significantly and consistently improving the symptoms of OAB as early as day 5 of treatment., a statistically significantly higher number of patients in placebo controlled clinical trials achieved a reduction in urgency and wet days by week 12 with Regurin(R) XL. Furthermore, Regurin(R) XL has the benefit of not crossing the blood- brain barrier, or the blood eye barrier reducing the CNS side effects sometimes associated with OAB treatments.
"Overactive bladder has a significant, and often underestimated, impact on the quality of life of all patients. In elderly dependent patients OAB can cause breakdown in care-giving relationships and even increase the likelihood of patients being admitted to a nursing home , said Professor Linda Cardozo, Kings College Hospital, London. "It is important to effectively treat OAB, to maintain confidence and independence in all patients. Ensuring patient compliance is an important consideration in treating patients with OAB. Therefore, the availability of cost effective, tried and tested treatment, with the convenience of once-daily dosing, and minimal side effects is welcome news for physicians and their patients".