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Trial shows safety of pre-transplant expansion of umbilical cord blood stem cells

Taking blood stem cells collected from an umbilical cord into the lab and expanding their number before transplanting them to replace a patient's blood supply is as safe as a standard cord blood transplant, researchers reported at the 50th Annual Meeting of the American Society of Hematology.

8 Dec 2008

Promising trials of malaria vaccine in East Africa lead to calls for phase 3 development

Experts are recommending that a malaria vaccine progress to Phase 3 trials following the successful trial of the RTS, S/AS01E malaria vaccine among 5-17 month old children in Korogwe, Tanzania and coastal Kenya, which is reported in the New England Journal of Medicine (NEJM).

8 Dec 2008

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

Genentech, Inc. and Biogen Idec have announced that two global Phase III studies in chronic lymphocytic leukemia (CLL), CLL8 and REACH, showed Rituxan (rituximab) plus chemotherapy significantly increased the time patients lived without their disease advancing, as defined by the primary endpoint of progression-free survival (PFS), when compared to chemotherapy alone.

8 Dec 2008

Effects of stem cell source and patient age on stem cell transplantation outcomes

Two studies examining the effects of stem cell source and patient age on stem cell transplantation outcomes were explored at a press conference on Sunday, December 7 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

New insights into development of the human immune system

A UCSF study has found that a surprisingly high number of maternal cells enters the fetus during pregnancy, prompting the generation of special immune cells in the fetus that suppress a response against the mother.

5 Dec 2008

Degarelix prostate cancer drug makes testosterone levels fall dramatically and quickly

More than 95 per cent of men who took degarelix for prostate cancer saw their testosterone levels fall dramatically as early as three days after they started treatment, according to a paper in the December issue of BJU International.

3 Dec 2008

New insight into adhesion and migration of dendritic cells could lead to novel cancer treatments

Our immune system plays an essential role in protecting us from diseases, but how does it do this exactly?

1 Dec 2008

EpiVax receives grant for $390,000 to optimize HIV vaccine delivery

EpiVax, Inc., a leader in the field of computational immunology, announced today that it has received a grant from the National Institute of Allergy and Infectious Diseases (NIAID), a division of the National Institutes of Health (NIH), to optimize delivery of an HIV vaccine.

26 Nov 2008

Immune cells reveal fancy footwork

Our immune system plays an essential role in protecting us from diseases, but how does it do this exactly?

25 Nov 2008

Scientists present 'moving' theory behind bacterial decision-making

Biochemists at North Carolina State University have answered a fundamental question of how important bacterial proteins make life-and-death decisions that allow them to function, a finding that could provide a new target for drugs to disrupt bacterial decision-making processes and related diseases.

24 Nov 2008

Medarex starts phase 1b clinical trial with MDX-1106 for the treatment of cancer

Medarex, Inc. has announced it has initiated a Phase 1b clinical trial for MDX-1106 (ONO-4538: development code of Ono Pharmaceutical Co., Ltd.), a fully human anti-PD-1 antibody for the treatment of cancer.

24 Nov 2008

Targeted nanoparticles boost platinum-based anticancer therapy

A research team from the Massachusetts Institute of Technology (MIT)-Harvard Center for Nanotechnology Excellence has custom-designed nanoparticles that can deliver the anticancer drug cisplatin specifically to prostate cancer cells.

20 Nov 2008

Viral Genetics completes acquisition of V-Clip Pharmaceuticals

Viral Genetics, Inc. has announced it has completed its acquisition of V-Clip Pharmaceuticals, Inc. ("V-Clip").

19 Nov 2008

First trachea transplant and first tissue transplant without immunosuppression

After 4 years of going from consultation to consultation, Claudia Castillo finally found a solution to her respiratory problems.

19 Nov 2008

Vaccine-related chronic fatigue syndrome in an individual demonstrating aluminium overload

A team of scientists have investigated a case of vaccine-associated chronic fatigue syndrome (CFS) and macrophagic myofasciitis in an individual demonstrating aluminium overload.

18 Nov 2008

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Genetic Immunity, a US/Hungarian clinical-stage company focused on development of nanomedicines for targeted immune amplification, today announced it has treated the first subject in a Phase II clinical study to evaluate DermaVir Patch.

13 Nov 2008

Strong relationship found between allergies and cancer in environmentally exposed tissues

There may be a silver -- and healthy -- lining to the miserable cloud of allergy symptoms: Sneezing, coughing, tearing and itching just may help prevent cancer -- particularly colon, skin, bladder, mouth, throat, uterus and cervix, lung and gastrointestinal tract cancer, according to a new Cornell study.

12 Nov 2008

Antigen News and Research

Trial shows safety of pre-transplant expansion of umbilical cord blood stem cells

Promising trials of malaria vaccine in East Africa lead to calls for phase 3 development

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

Effects of stem cell source and patient age on stem cell transplantation outcomes

New insights into development of the human immune system

Degarelix prostate cancer drug makes testosterone levels fall dramatically and quickly

New insight into adhesion and migration of dendritic cells could lead to novel cancer treatments

EpiVax receives grant for $390,000 to optimize HIV vaccine delivery

Immune cells reveal fancy footwork

Scientists present 'moving' theory behind bacterial decision-making

Medarex starts phase 1b clinical trial with MDX-1106 for the treatment of cancer

Targeted nanoparticles boost platinum-based anticancer therapy

Viral Genetics completes acquisition of V-Clip Pharmaceuticals

First trachea transplant and first tissue transplant without immunosuppression

Vaccine-related chronic fatigue syndrome in an individual demonstrating aluminium overload

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Strong relationship found between allergies and cancer in environmentally exposed tissues

Breakthrough in rheumatoid arthritis research

All stem cells are not created equal, explains expert

Astragalus root plant chemical used to fight HIV

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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