Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Treatment of Gastric Varices

Irritable Bowel Syndrome (IBS) Comorbidities

Irritable Bowel Syndrome (IBS) Food Triggers

Dermatitis Herpetiformis and Celiac Disease

What is Gastroenterology?

Low FODMAP Diet

What is Gastroenteritis?

Malrotation of the Gastrointestinal Tract

Gastritis Diagnosis

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

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Gastric Varices - Signs and Symptoms

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

High FODMAP Foods and Low FODMAP Food Alternatives

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Fermented Foods and Gut Health

Is Dermatitis Herpetiformis Caused by Herpes?

Antibiotics and the Microbiome

Gastric Bypass Criteria

What is Gastroparesis?

Celiac Disease Pathogenesis

Microbiome and Disease

Causes of Irritable Bowel Syndrome

Celiac Disease Screening

Alzheimer's Disease and the Microbiome

What is Ulcerative Colitis?

Does Wheat Cause Gut Inflammation?

Mesentery: a new organ?

What is Gastritis?

What is Irritable Bowel Syndrome?

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Treatment of Irritable Bowel Syndrome

Fecal Microbiota Transplant Technique

Risk Factors for Small Intestinal Bacterial Overgrowth

Skin Microbiota

Oral Microbiota

What is a Gastric Bypass?

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastroschisis Causes

Symptoms of Irritable Bowel Syndrome

Microbiome and Cancer

Mechanism of Irritable Bowel Syndrome (IBS)

FODMAP Research

Genetics of Inflammatory Bowel Disease (IBD)

What is Gluten?

Irritable Bowel Syndrome (IBS) Epidemiology

Gastritis Causes

Irritable Bowel Syndrome (IBS) Prognosis

Gastroparesis Epidemiology

Parkinson's Disease and the Gut Microbiome

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Gastric Bypass Benefits

Gastrointestinal Bleeding Treatment

Gastroparesis Causes

Self-Help for Irritable Bowel Syndrome (IBS)

Treatment and Prognosis for Intestinal Malrotation

Gastrointestinal Stromal Tumor (GIST) Causes

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Irritable Bowel Syndrome (IBS) and Exercise

Probiotics and IBS

Gastrointestinal Disease and Skin Problems

Diagnosis of Irritable Bowel Syndrome

What is Gastrointestinal Bleeding?

Irritable Bowel Syndrome (IBS) and Diet

Dysbiosis and Aging

Human Microbiome

Conjunctiva microbiota

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Effects of a Gluten-Free Diet on the Gut Microbiota

Gastritis Treatments

How Does the Diet Impact Microbiota?

How to Recover Gut Health After Clostridium difficile Infection

Dysbiosis and the Microbiome

Human Microbiome Project (HMP)

Gastric Varices

What does Sleeve Gastrectomy Involve?

Irritable Bowel Syndrome (IBS) Psychological Therapies

Microbiome-Host Cell Interactions

Symptoms and Diagnosis of Intestinal Malrotation

Gut Microbiota

Celiac Disease Treatment

FODMAPs and Irritable Bowel Syndrome (IBS)

Disease Susceptibility and the Microbiome

Drug Metabolism and Microbiome

Fecal Microbiota Transplant

Irritable Bowel Syndrome (IBS) and Stress Response

Inflammatory Bowel Disease (IBD) in Pregnancy

Post-Infectious Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) and Infections

The Microbiome and Aging

Gastrointestinal Stromal Tumor Pathogenesis

Fecal Microbiota Transplant Regulation

Sarin Classification of Gastric Varices

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Does the Microbiome Interact with the Human Endocrine System?

Do Serotonin and Antidepressants Affect the Microbiome?

Gastritis Symptoms

Inflammatory Bowel Disease and Colorectal Cancer

Gastroparesis and Diet

Achievements of the Human Microbiome Project

Gastric Bypass Types

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Gastroschisis Prognosis

Gastroparesis Diagnosis

Short-Chain Fatty Acids (SCFAs)

Gastrointestinal Stromal Tumor (GIST) Treatment

Gastrointestinal Bleeding Symptoms

Gastroparesis Treatments

Types of Gastrectomy

After Gastric Bypass Surgery

What is Gastroschisis?

Gastric Carcinoma

Is There a Link Between Migraine and the Gut Microbiome?

Gastric Bypass Complications

Diabetic Gastroparesis

What is Celiac Disease?

Gastroparesis Symptoms

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Irritable Bowel Syndrome (IBS) Research

Ulcerative Colitis Causes

Crohn's Disease Cause

Gut-on-a-Chip to Model Coeliac Disease

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

What is Vaginal Microbiome?

Celiac Disease Symptoms

Celiac Disease Diagnosis

Latest Gastrointestinal Health News and Research

Postbiotics may help treat PCOS by restoring microbiome balance

Emerging studies suggest postbiotics could aid PCOS management by restoring gut microbiome balance and enhancing insulin sensitivity and hormonal regulation.

10 Mar 2026

Hormonal imbalance and gut microbes linked to cognitive deficits in patients with PitNETs

Pituitary neuroendocrine tumors (PitNETs) are commonly associated with visual disturbances and endocrine abnormalities; however, many patients also experience cognitive deficits, particularly in memory, attention, and executive function, which significantly affect quality of life.

9 Mar 2026

Specific gut bacteria may signal long-term risk of heart and metabolic disease

Researchers analyzed gut microbiome profiles from 4,792 adults in the HELIUS cohort and tracked cardiometabolic outcomes over time to determine whether specific microbes predict disease risk. Certain microbes were linked to higher or lower cardiovascular risk, while plant-derived microbial metabolites suggested potential diet–microbiome interactions influencing heart health.

9 Mar 2026

Microbial ecosystems influence success of cancer checkpoint immunotherapy

Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.

9 Mar 2026

Protein aggregates in the liver may protect against alcohol-induced damage

Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.

9 Mar 2026

New compound shows promise in protecting the liver from damage after small bowel surgery

When parts of the small intestine are diseased or die, the treatment can involve surgically removing the affected tissue.

6 Mar 2026

Melbourne’s lab-grown "skin" revolutionizes tick research

The world's first lab-based tick feeding system for bush ticks, developed by researchers at the University of Melbourne, has transformed the study of ticks and how they transmit disease. The novel, host-free technology reduces the need for animal experiments in tick studies, facilitating more ethical, reproducible research.

5 Mar 2026

Researchers propose that Parkinson’s disease may start in the gut, not the brain

A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.

5 Mar 2026

Tufts researchers identify new vulnerabilities to combat persistent C. diff infections

Affecting roughly half a million Americans each year, bacterial infections caused by Clostridioides difficile—commonly known as C. diff—are a serious and persistent problem for patients and hospitals alike.

5 Mar 2026

No evidence probiotic skincare can improve mood

Current findings reveal no support for emotional benefits from probiotic cosmetics, highlighting the need for further investigation into neurocosmetics.

5 Mar 2026

Berries, apples, and citrus linked to greater happiness and optimism

A study links flavonoid-rich diets to sustained happiness and optimism, highlighting the bidirectional relationship between diet and psychological well-being.

5 Mar 2026

Microbial taxa more likely to be found in people with dyslipidemia

Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood.

4 Mar 2026

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity.

4 Mar 2026

Alcohol abstinence can lead to regression of existing liver-related complications

Consistent and permanent abstinence from alcohol can lead to the regression of existing liver-related complications, even in cases of advanced alcohol-related cirrhosis.

4 Mar 2026

New strategy targets Porphyromonas gingivalis without harming healthy microbes

For years, treating gum disease has meant scraping away plaque, cutting out damaged tissue or turning to antibiotics that kill bacteria indiscriminately.

3 Mar 2026

Gut bacteria may explain differences in peanut allergy reactions

One of the big mysteries in food allergy is why two people with similar levels of peanut specific antibodies can react so differently. It turns out the answer may be in the mouth and gut's bacteria.

3 Mar 2026

Study links high-fat diet to faster breast cancer progression

If you're diagnosed with breast cancer, what should you eat to ensure the best prognosis?

3 Mar 2026

New collaboration explores familial inflammatory bowel disease in Saudi Arabia

Mount Sinai and King Saud University Medical City in Riyadh, Saudi Arabia, today announced a three-year collaboration aimed at better understanding why inflammatory bowel disease (IBD) runs in some Saudi families, and how that knowledge can lead to risk ascertainment, earlier diagnosis and more personalized treatment options.

3 Mar 2026

Study links gut microbiome health directly to ovarian aging processes

A new study details how fecal transplants from older female mice significantly improve ovarian function and fertility in young mice. The surprising results reveal a direct link between the microbiome (the collection of all bacteria and other microbes present) of the gut and ovarian health and function.

3 Mar 2026

Experts identify safest and most effective diets for IBS management

This review in Nutrients evaluates the scientific evidence, clinical effectiveness, and safety of major dietary strategies for irritable bowel syndrome, including traditional advice, low-FODMAP, gluten-free, Mediterranean, and starch- and sucrose-reduced diets. It concludes that while the low-FODMAP diet has the strongest short-term evidence, no single approach fits all patients, and dietitian-led personalization is essential.

2 Mar 2026