Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Gastric Bypass Criteria

Fecal Microbiota Transplant

Conjunctiva microbiota

What does Sleeve Gastrectomy Involve?

Gastroparesis Causes

Crohn's Disease Cause

Genetics of Inflammatory Bowel Disease (IBD)

Irritable Bowel Syndrome (IBS) and Infections

Gastroparesis Epidemiology

Gastroschisis Prognosis

Probiotics and IBS

See more featured articles »

Gut Microbiota

What is Gluten?

Symptoms of Irritable Bowel Syndrome

Gastric Bypass Types

Celiac Disease Pathogenesis

Gastroparesis Diagnosis

Microbiome and Disease

Gastritis Diagnosis

Irritable Bowel Syndrome (IBS) Food Triggers

Gastric Carcinoma

Types of Gastrectomy

Irritable Bowel Syndrome (IBS) Comorbidities

After Gastric Bypass Surgery

Treatment of Gastric Varices

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Celiac Disease Treatment

Irritable Bowel Syndrome (IBS) Prognosis

Does the Microbiome Interact with the Human Endocrine System?

Irritable Bowel Syndrome (IBS) Epidemiology

What is Gastrointestinal Bleeding?

Human Microbiome

Mechanism of Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Gastrointestinal Disease and Skin Problems

Gastrointestinal Bleeding Symptoms

What is Gastritis?

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Post-Infectious Irritable Bowel Syndrome

Gastrointestinal Stromal Tumor Pathogenesis

Gastric Bypass Benefits

Celiac Disease Symptoms

Irritable Bowel Syndrome (IBS) and Exercise

What is Gastroenterology?

Gastroschisis Causes

Gastrointestinal Bleeding Treatment

Diabetic Gastroparesis

Gastrointestinal Stromal Tumor (GIST) Treatment

How to Recover Gut Health After Clostridium difficile Infection

Low FODMAP Diet

Celiac Disease Screening

Parkinson's Disease and the Gut Microbiome

What is a Gastric Bypass?

Oral Microbiota

Mesentery: a new organ?

What is Irritable Bowel Syndrome?

Alzheimer's Disease and the Microbiome

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

FODMAP Research

What is Gastroschisis?

Is There a Link Between Migraine and the Gut Microbiome?

Treatment and Prognosis for Intestinal Malrotation

Irritable Bowel Syndrome (IBS) Psychological Therapies

Fecal Microbiota Transplant Regulation

Is Dermatitis Herpetiformis Caused by Herpes?

Diagnosis of Irritable Bowel Syndrome

Do Serotonin and Antidepressants Affect the Microbiome?

Does Wheat Cause Gut Inflammation?

Drug Metabolism and Microbiome

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Symptoms and Diagnosis of Intestinal Malrotation

How Does the Diet Impact Microbiota?

Gastroparesis Symptoms

Gastric Varices

Dermatitis Herpetiformis and Celiac Disease

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Gastritis Causes

Gastrointestinal Stromal Tumor (GIST) Causes

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Microbiome-Host Cell Interactions

Fecal Microbiota Transplant Technique

Human Microbiome Project (HMP)

Dysbiosis and Aging

FODMAPs and Irritable Bowel Syndrome (IBS)

Gut-on-a-Chip to Model Coeliac Disease

What is Vaginal Microbiome?

Causes of Irritable Bowel Syndrome

Microbiome and Cancer

Gastric Bypass Complications

Short-Chain Fatty Acids (SCFAs)

Irritable Bowel Syndrome (IBS) Research

Gastritis Symptoms

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Dysbiosis and the Microbiome

The Microbiome and Aging

Sarin Classification of Gastric Varices

Antibiotics and the Microbiome

Celiac Disease Diagnosis

Disease Susceptibility and the Microbiome

Gastritis Treatments

Ulcerative Colitis Causes

Irritable Bowel Syndrome (IBS) and Diet

High FODMAP Foods and Low FODMAP Food Alternatives

Risk Factors for Small Intestinal Bacterial Overgrowth

Gastric Varices - Signs and Symptoms

Self-Help for Irritable Bowel Syndrome (IBS)

What is Celiac Disease?

Inflammatory Bowel Disease (IBD) in Pregnancy

What is Gastroenteritis?

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Irritable Bowel Syndrome (IBS) and Stress Response

Skin Microbiota

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Effects of a Gluten-Free Diet on the Gut Microbiota

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Gastroparesis and Diet

Inflammatory Bowel Disease and Colorectal Cancer

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastroparesis Treatments

Treatment of Irritable Bowel Syndrome

Malrotation of the Gastrointestinal Tract

Fermented Foods and Gut Health

Achievements of the Human Microbiome Project

What is Ulcerative Colitis?

What is Gastroparesis?

Latest Gastrointestinal Health News and Research

Cornell study finds existing drug could boost liver cancer immunotherapy

Immunotherapy – which activates the body's own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment.

17 Feb 2026

AI tool can accurately predict colorectal cancer risk in UC-LGD patients

People with ulcerative colitis (UC), a chronic inflammatory bowel disease, are up to four times more likely to develop colorectal cancer than the general population.

17 Feb 2026

Study links microbe-rich diets with better insulin and cholesterol markers

This exploratory Australian study developed a database to estimate live microbe content in foods and examined associations with cardiometabolic health indicators in adults. Higher intake of foods estimated to contain live microbes was linked with favourable markers such as higher HDL cholesterol and lower BMI, insulin, and waist circumference, although causality cannot be inferred.

16 Feb 2026

Chronic inflammation shapes cancer progression and immunotherapy response

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

16 Feb 2026

Dysplasia grade predicts colorectal cancer risk in people with IBD

People with inflammatory bowel disease (IBD) and precancerous colorectal lesions are much more likely to develop colorectal cancer, a new study shows.

16 Feb 2026

Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits

A randomized crossover weight loss trial in adults with overweight or obesity found that higher protein big breakfasts improved satiety, while higher fibre breakfasts produced slightly greater weight loss and more favourable gut microbiota markers. Both diets improved metabolic biomarkers, but microbiota changes reflected surrogate gut health indicators rather than direct clinical outcomes.

15 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Genetic variants in 11 regions of human genome influence the gut microbiome

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there.

13 Feb 2026

Distinct microbial signature identified in pediatric Crohn's disease

NYU researchers have found a "microbial signature" of pediatric Crohn's disease that differs from the makeup of gut bacteria in children with other gastrointestinal conditions, with Crohn's patients harboring more pro-inflammatory bacteria and less protective bacteria.

12 Feb 2026

Top early-life factors driving childhood food allergy

This study analyzes 190 research papers to uncover early-life predictors of food allergies in children, highlighting skin barrier health and family history.

12 Feb 2026

High-fat diets cause more damage to metabolic health than carbohydrates

In recent years, many media reports and social media influencers have emphasized the dangers of eating too many carbohydrates.

10 Feb 2026

First wearable device measures human flatulence

Scientists at the University of Maryland have created Smart Underwear, the first wearable device designed to measure human flatulence.

10 Feb 2026

Microbial generalists form planet-wide networks across ecosystems

In a new study published in Cell, scientists in the Bork Group at EMBL Heidelberg reveal that microbes living in similar habitats are more alike than those simply inhabiting the same geographical region.

10 Feb 2026

New genetic model reveals role of keratin 8 in colorectal cancer development

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients.

10 Feb 2026

Obesity drives one in ten infectious disease deaths

Just over one in 10 deaths from a wide range of infectious diseases can be attributed to obesity worldwide, finds a major new study led by a University College London (UCL) researcher.

9 Feb 2026

Early life factors crucial for childhood food allergy development

A new study from McMaster University involving 2.8 million children around the world has revealed the most important early-life factors that influence whether a child becomes allergic to food.

9 Feb 2026

Time-restricted feeding reduces disease activity and inflammation in Crohn's patients

A new randomized controlled study funded by the Crohn's & Colitis Foundation found that time-restricted feeding-a form of intermittent fasting-significantly reduced symptomatic disease activity and systematic inflammation in adults with Crohn's disease and overweight or obesity.

9 Feb 2026

Study identifies link between gut bacteria and deterioration of the brain in ALS, dementia

A significant discovery by Case Western Reserve University researchers could change how doctors treat two of the most devastating neurodegenerative diseases.

9 Feb 2026

CRISPR gene-drive technology reverses antibiotic resistance in bacteria

Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of "superbugs" have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050.

7 Feb 2026

Gut bacteria use formic acid as an electron taxi

Among the many trillions of microorganisms in the human gut is Blautia luti. Like many gut bacteria, it metabolizes indigestible dietary components, such as fiber in the form of carbohydrates.

7 Feb 2026