Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

What is Celiac Disease?

What is a Gastric Bypass?

Short-Chain Fatty Acids (SCFAs)

Gastric Carcinoma

Dermatitis Herpetiformis and Celiac Disease

Irritable Bowel Syndrome (IBS) Differential Diagnosis

How Does the Diet Impact Microbiota?

Crohn's Disease Cause

Irritable Bowel Syndrome (IBS) Epidemiology

Gastroparesis Treatments

Diagnosis of Irritable Bowel Syndrome

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Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Treatment and Prognosis for Intestinal Malrotation

Symptoms and Diagnosis of Intestinal Malrotation

Types of Gastrectomy

Gastrointestinal Stromal Tumor (GIST) Treatment

Post-Infectious Irritable Bowel Syndrome

Microbiome and Cancer

Mesentery: a new organ?

What does Sleeve Gastrectomy Involve?

Inflammatory Bowel Disease (IBD) in Pregnancy

Gastritis Diagnosis

Alzheimer's Disease and the Microbiome

Probiotics and IBS

Irritable Bowel Syndrome (IBS) Food Triggers

Gastrointestinal Stromal Tumor Pathogenesis

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Gastric Bypass Criteria

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Inflammatory Bowel Disease and Colorectal Cancer

Causes of Gastro-Esophageal Reflux Disease (GERD)

What is Gastroenteritis?

Is Dermatitis Herpetiformis Caused by Herpes?

What is Gastrointestinal Bleeding?

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

What is Gastroenterology?

Gastric Bypass Benefits

After Gastric Bypass Surgery

FODMAPs and Irritable Bowel Syndrome (IBS)

Celiac Disease Diagnosis

Malrotation of the Gastrointestinal Tract

Fecal Microbiota Transplant

Is There a Link Between Migraine and the Gut Microbiome?

Symptoms of Irritable Bowel Syndrome

Self-Help for Irritable Bowel Syndrome (IBS)

Gut Microbiota

Microbiome and Disease

Does Wheat Cause Gut Inflammation?

Sarin Classification of Gastric Varices

Genetic Factors that Influence Bacterial Diversity in the Human Gut

High FODMAP Foods and Low FODMAP Food Alternatives

Gastric Bypass Types

Gastrointestinal Disease and Skin Problems

Does the Microbiome Interact with the Human Endocrine System?

Achievements of the Human Microbiome Project

Celiac Disease Treatment

What is Vaginal Microbiome?

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Gastroparesis Epidemiology

Gastroschisis Prognosis

The Microbiome and Aging

Microbiome-Host Cell Interactions

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Genetics of Inflammatory Bowel Disease (IBD)

Parkinson's Disease and the Gut Microbiome

Skin Microbiota

What is Gastroparesis?

FODMAP Research

Diabetic Gastroparesis

Gastric Bypass Complications

Irritable Bowel Syndrome (IBS) Comorbidities

Irritable Bowel Syndrome (IBS) and Exercise

Causes of Irritable Bowel Syndrome

Gastritis Symptoms

Irritable Bowel Syndrome (IBS) Psychological Therapies

Gastrointestinal Bleeding Treatment

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Drug Metabolism and Microbiome

Human Microbiome Project (HMP)

Gastroparesis Symptoms

Gut-on-a-Chip to Model Coeliac Disease

Gastritis Treatments

Gastroparesis Causes

What is Irritable Bowel Syndrome?

Risk Factors for Small Intestinal Bacterial Overgrowth

What is Ulcerative Colitis?

Effects of a Gluten-Free Diet on the Gut Microbiota

Human Microbiome

Treatment of Irritable Bowel Syndrome

Mechanism of Irritable Bowel Syndrome (IBS)

Fecal Microbiota Transplant Regulation

Fermented Foods and Gut Health

What is Gastritis?

Disease Susceptibility and the Microbiome

Low FODMAP Diet

Gastroschisis Causes

Gastroparesis and Diet

Gastrointestinal Bleeding Symptoms

What is Gluten?

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Conjunctiva microbiota

What is Gastroschisis?

Celiac Disease Screening

Irritable Bowel Syndrome (IBS) Research

Gastroparesis Diagnosis

Irritable Bowel Syndrome (IBS) and Stress Response

Irritable Bowel Syndrome (IBS) and Infections

Oral Microbiota

Celiac Disease Symptoms

Do Serotonin and Antidepressants Affect the Microbiome?

Irritable Bowel Syndrome (IBS) Prognosis

Celiac Disease Pathogenesis

Dysbiosis and the Microbiome

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Gastritis Causes

Treatment of Gastric Varices

Irritable Bowel Syndrome (IBS) and Diet

Ulcerative Colitis Causes

Gastric Varices - Signs and Symptoms

Gastrointestinal Stromal Tumor (GIST) Causes

Antibiotics and the Microbiome

Fecal Microbiota Transplant Technique

How to Recover Gut Health After Clostridium difficile Infection

Gastric Varices

Dysbiosis and Aging

Latest Gastrointestinal Health News and Research

AGA update calls for better surveillance of hepatocellular carcinoma

A new update from the American Gastroenterological Association (AGA) urges stronger prevention efforts and better early-detection tools for hepatocellular carcinoma (HCC), the leading cause of cancer-related death in patients with cirrhosis, and the third most common cause of cancer-related death worldwide.

17 Apr 2026

Gut bacteria predict melanoma recurrence risk after treatment

The specific mix of bacteria living in a person's gut can predict the chances that melanoma will recur after surgery and immunotherapy, a treatment that helps immune cells target cancer cells. This is according to a new study led by researchers from NYU Langone Health and its Perlmutter Cancer Center.

17 Apr 2026

When rice-based formula is the right choice for cow’s milk allergy

This expert-driven framework aids clinicians in selecting hydrolyzed rice formula for infants with cow's milk allergy, enhancing dietary management strategies.

17 Apr 2026

Scientists link poor sleep to decreased chemotherapy response via the gut

Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.

17 Apr 2026

Gut-liver changes drive foodborne infection severity in fatty liver disease

A research team led by the University of California, Irvine's Joe C. Wen School of Population & Public Health has uncovered a critical biological link explaining why individuals with metabolic dysfunction–associated steatotic liver disease (MASLD), or fatty liver disease, face significantly worse outcomes from certain foodborne infections.

15 Apr 2026

New biochip detects tiny genetic markers in 20 minutes

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has developed a new biochip that, when paired with Artificial Intelligence (AI), can detect quickly and accurately extremely small amounts of microRNAs, which are tiny genetic markers linked to diseases such as heart disease.

15 Apr 2026

Study shows why an apple a day may work differently for different people

A 12-week single-blind trial in 38 Japanese adults found that daily Fuji apple intake did not significantly change overall host metabolic markers, but responses differed by baseline gut enterotype. Participants in the Bacteroidaceae-dominant enterotype showed significant increases in fecal short-chain fatty acids after apple consumption, suggesting that gut microbiota structure may shape functional dietary responses.

13 Apr 2026

Higher mortality risk in IBS patients using antidepressants

Research indicates that antidepressant use in IBS is linked to a 35% higher risk of all-cause mortality, highlighting safety issues with long-term treatment.

13 Apr 2026

Dietitians report widely different strategies for FODMAP food reintroduction in IBS

A national survey of 145 registered dietitians found wide variation in how the low FODMAP diet’s reintroduction phase is delivered, especially in dosing, timing, sequencing, and follow-up. The findings suggest that clearer, evidence-based protocols could improve consistency while still allowing individualized care.

12 Apr 2026

Damon Runyon supports young scientists driving cancer research innovation

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

11 Apr 2026

Early epigenetic changes shape infant gut microbiome development

The gut microbiome and epigenetics-molecular switches that turn genes on or off-are intertwined, and both contribute to neurodevelopment, finds a study publishing April 10 in the Cell Press journal Cell Press Blue.

10 Apr 2026

Popular sweeteners may impact metabolism across generations

When you choose a diet version of your favorite fizzy drink, you consume non-nutritive sweeteners, which taste sweet but - unlike sugar - contain no calories.

10 Apr 2026

New technique finds bacteria to increase the vitamin B2 content of soya drinks

Researchers at DTU have developed a new method that can reduce the time needed to find new bacteria for fermentation.

10 Apr 2026

When omega-3 may help mental health and when they may not

Investigating omega-3 fatty acids, this review highlights their impact on mental health, inflammation, and the potential for therapeutic use in disorders.

10 Apr 2026

IBS diagnosis gaps persist across racial and gender groups in the U.S.

A national survey study led by UCLA Health and Cedars-Sinai Medical Center found significant disparities in how irritable bowel syndrome, or IBS, is diagnosed across sex and racial groups in the U.S., with men and Black patients considerably less likely than women and white patients to receive a formal diagnosis.

9 Apr 2026

Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours

Researchers found that cola exposure quickly lowered pH and altered the microbiome on the inner surface of clear aligners, with the greatest disruption observed when aligners were removed before drinking and then reinserted. In this small 24-hour study, wearing aligners during exposure appeared less disruptive than removing them, though the authors said the mechanism still needs further study.

8 Apr 2026

Long-term study links common IBS medications to mortality risk

A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)-including antidepressants-may be associated with a small but measurable increase in the risk of death.

8 Apr 2026

Intimacy study offers reassuring news for celiac-discordant couples

For people living with celiac disease, the fear of gluten exposure can extend beyond food - sometimes even into moments of intimacy.

8 Apr 2026

AI tool predicts Barrett’s esophagus recurrence with high accuracy

A new artificial intelligence (AI)–based tool shows promise for improving surveillance in patients treated with endoscopic eradication therapies for Barrett's esophagus (BE) related dysplasia and early esophageal adenocarcinoma.

7 Apr 2026

Fecal microbiota transplant can improve survival in severe C. difficile infection

A new study from the University of Minnesota Medical School demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile (C. difficile) infection - a life-threatening condition characterized by a sepsis-like state.

6 Apr 2026