Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Celiac Disease Diagnosis

Crohn's Disease Cause

Human Microbiome Project (HMP)

Parkinson's Disease and the Gut Microbiome

Is Dermatitis Herpetiformis Caused by Herpes?

Gastroparesis Treatments

Gastrointestinal Stromal Tumor Pathogenesis

Dysbiosis and the Microbiome

Microbiome and Cancer

Ulcerative Colitis Causes

What is Gastritis?

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Gastroparesis Diagnosis

What is Ulcerative Colitis?

Symptoms of Irritable Bowel Syndrome

Dermatitis Herpetiformis and Celiac Disease

Dysbiosis and Aging

Genetics of Inflammatory Bowel Disease (IBD)

Celiac Disease Symptoms

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Causes of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) and Stress Response

Treatment and Prognosis for Intestinal Malrotation

Mechanism of Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) and Exercise

What is Irritable Bowel Syndrome?

Effects of a Gluten-Free Diet on the Gut Microbiota

Microbiome-Host Cell Interactions

Does Wheat Cause Gut Inflammation?

Risk Factors for Small Intestinal Bacterial Overgrowth

Diagnosis of Irritable Bowel Syndrome

Fermented Foods and Gut Health

Gastritis Symptoms

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Gastric Carcinoma

Oral Microbiota

Gut-on-a-Chip to Model Coeliac Disease

Gastric Varices - Signs and Symptoms

FODMAPs and Irritable Bowel Syndrome (IBS)

Does the Microbiome Interact with the Human Endocrine System?

Irritable Bowel Syndrome (IBS) Differential Diagnosis

FODMAP Research

Drug Metabolism and Microbiome

Gastrointestinal Stromal Tumor (GIST) Causes

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Irritable Bowel Syndrome (IBS) and Fibromyalgia

What is Gastrointestinal Bleeding?

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Skin Microbiota

Causes of Irritable Bowel Syndrome

Gastrointestinal Bleeding Treatment

Irritable Bowel Syndrome (IBS) Research

Irritable Bowel Syndrome (IBS) Prognosis

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Gastritis Causes

Irritable Bowel Syndrome (IBS) Epidemiology

Types of Gastrectomy

Microbiome and Disease

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Disease Susceptibility and the Microbiome

Treatment of Gastric Varices

Do Serotonin and Antidepressants Affect the Microbiome?

Fecal Microbiota Transplant Technique

Celiac Disease Treatment

What is Gastroparesis?

Sarin Classification of Gastric Varices

After Gastric Bypass Surgery

What does Sleeve Gastrectomy Involve?

Antibiotics and the Microbiome

Irritable Bowel Syndrome (IBS) Comorbidities

Fecal Microbiota Transplant Regulation

Inflammatory Bowel Disease (IBD) in Pregnancy

Gastroparesis Symptoms

Diabetic Gastroparesis

Gastrointestinal Stromal Tumor (GIST) Treatment

Gastrointestinal Bleeding Symptoms

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Gastrointestinal Disease and Skin Problems

Short-Chain Fatty Acids (SCFAs)

Inflammatory Bowel Disease and Colorectal Cancer

Post-Infectious Irritable Bowel Syndrome

Conjunctiva microbiota

Gut Microbiota

Achievements of the Human Microbiome Project

How to Recover Gut Health After Clostridium difficile Infection

The Microbiome and Aging

Human Microbiome

Mesentery: a new organ?

Gastroparesis Epidemiology

What is a Gastric Bypass?

Celiac Disease Pathogenesis

Gastric Bypass Criteria

High FODMAP Foods and Low FODMAP Food Alternatives

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Malrotation of the Gastrointestinal Tract

Gastric Bypass Complications

Low FODMAP Diet

What is Gastroenterology?

Symptoms and Diagnosis of Intestinal Malrotation

How Does the Diet Impact Microbiota?

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Probiotics and IBS

Gastric Bypass Types

What is Celiac Disease?

Gastric Varices

What is Vaginal Microbiome?

Irritable Bowel Syndrome (IBS) Psychological Therapies

Gastroschisis Causes

Gastritis Treatments

Gastric Bypass Benefits

Gastritis Diagnosis

Celiac Disease Screening

Fecal Microbiota Transplant

Is There a Link Between Migraine and the Gut Microbiome?

Irritable Bowel Syndrome (IBS) and Infections

Gastroschisis Prognosis

Irritable Bowel Syndrome (IBS) Food Triggers

Gastroparesis and Diet

What is Gastroenteritis?

Gastroparesis Causes

Irritable Bowel Syndrome (IBS) and Diet

What is Gluten?

What is Gastroschisis?

Treatment of Irritable Bowel Syndrome

Alzheimer's Disease and the Microbiome

Self-Help for Irritable Bowel Syndrome (IBS)

Latest Gastrointestinal Health News and Research

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

In a major step towards a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to block C. diff's most dangerous toxin.

9 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Supportive marriages may shape appetite control through oxytocin and the brain–gut axis

Supportive marital relationships are associated with lower BMI, fewer food addiction symptoms, higher oxytocin, stronger frontal brain responses to food cues, and favorable gut tryptophan metabolites. These coordinated social, neural, hormonal, and gut pathways suggest a plausible biological link between emotional support and healthier eating regulation.

8 Dec 2025

Industrial and farm chemicals quietly alter the balance of gut microbes

This study systematically screened over 1,000 agricultural and industrial chemicals and found that many can inhibit human gut bacteria in vitro. Beyond antimicrobial effects, these chemicals act as selective pressures that can reshape microbial competition, tolerance mechanisms, and metabolic pathways.

8 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

An international research team led by Professor Marc-Emmanuel Dumas at Imperial College London & CNRS together with Prof. Patrice Cani (Imperial & University of Louvain, UCLouvain), Dr. Dominique Gauguier (Imperial & INSERM, Paris) and Prof. Peter Liu (University of Ottawa Heart Institute) has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine (TMA).

8 Dec 2025

Blood sugar migration to saliva fuels cavity development in type 2 diabetes patients

Individuals with type 2 diabetes often have a higher incidence of tooth decay, but the underlying mechanisms remain unclear.

8 Dec 2025

$New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer$

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs.

5 Dec 2025

Gut bacteria produce immune-boosting compounds in response to tetracyclines

The microbes inside our bodies not only help break down food but also impact our health. Yet their precise influence is not always understood, especially in the presence of prescription drugs.

3 Dec 2025

Study finds link between Pg-induced periapical disease and systemic metabolic dysfunction

New study examines the oral pathogen Porphyromonas gingivalis (Pg) and suggests its influence may extend beyond dental tissues.

3 Dec 2025

11 genetic loci that shape impulsive decision-making

Researchers identify distinct genetic loci involved in delay discounting and how these variants are involved in physical and psychiatric health outcomes.

3 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

Pneumococcal vaccination lowers antibiotic-resistant bacteria in children

Children in Guatemala who received a common vaccine that helps prevent pneumonia were less likely to carry antibiotic-resistant bacteria, according to a new study led by Washington State University researchers.

2 Dec 2025

Nasal bacteria influence Staphylococcus aureus colonization

People who persistently carry Staphylococcus aureus (S. aureus) in their nose have fewer species of other bacteria, while certain bacteria may help to prevent S. aureus colonisation.

2 Dec 2025

Asian IBD patients show lower PSC prevalence and better clinical outcomes

Primary sclerosing cholangitis (PSC) is a chronic, progressive inflammatory disease characterized by fibrosis and bile duct stricturing, which ultimately leads to cirrhosis and liver failure. PSC is strongly associated with both types of inflammatory bowel disease (IBD), namely, ulcerative colitis and Crohn's disease.

2 Dec 2025

International collaboration develops STREAMS to standardize microbiome data

Microbiomes, the communities of microorganisms that live in and around us, play a vital role in everything from human health to soil fertility and climate regulation. But studying these tiny life forms, especially outside the human body, presents a major challenge: how do scientists share complex data across such a wide range of environments and disciplines?

2 Dec 2025

Atelerix and Labskin partner to enable long-distance transport of advanced in vitro skin models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced an agreement with Labskin, a global leader in laboratory-grown human skin models used for research, testing and product development.

2 Dec 2025

Study provides new hope for future treatment of intestinal condition IBS

Researchers at örebro University in Sweden have made a significant advance in understanding the intestinal condition IBS.

2 Dec 2025

How the gut microbiome links obesity to colorectal cancer

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and colorectal cancer.

28 Nov 2025

Study demonstrates a safer strategy for allogeneic stem cell transplants

In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome-offering hope for safer, more effective treatment of blood cancers.

27 Nov 2025