Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

How to Recover Gut Health After Clostridium difficile Infection

Gastrointestinal Stromal Tumor Pathogenesis

Gastroparesis Symptoms

After Gastric Bypass Surgery

Does Wheat Cause Gut Inflammation?

Do Serotonin and Antidepressants Affect the Microbiome?

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Dermatitis Herpetiformis and Celiac Disease

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Conjunctiva microbiota

See more featured articles »

FODMAPs and Irritable Bowel Syndrome (IBS)

Probiotics and IBS

What is Gastritis?

Genetics of Inflammatory Bowel Disease (IBD)

Gastroschisis Causes

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Irritable Bowel Syndrome (IBS) Research

Risk Factors for Small Intestinal Bacterial Overgrowth

Celiac Disease Symptoms

Irritable Bowel Syndrome (IBS) and Infections

Treatment of Gastric Varices

Gastric Varices

Gastric Bypass Complications

Gastritis Causes

FODMAP Research

High FODMAP Foods and Low FODMAP Food Alternatives

Types of Gastrectomy

Causes of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) Differential Diagnosis

What is Ulcerative Colitis?

Inflammatory Bowel Disease (IBD) in Pregnancy

Symptoms of Irritable Bowel Syndrome

Malrotation of the Gastrointestinal Tract

Sarin Classification of Gastric Varices

Crohn's Disease Cause

Disease Susceptibility and the Microbiome

Post-Infectious Irritable Bowel Syndrome

Gastroparesis and Diet

Achievements of the Human Microbiome Project

Gastritis Treatments

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Gastric Bypass Types

Celiac Disease Treatment

The Microbiome and Aging

Irritable Bowel Syndrome (IBS) Epidemiology

Ulcerative Colitis Causes

Irritable Bowel Syndrome (IBS) Prognosis

Celiac Disease Screening

Skin Microbiota

Drug Metabolism and Microbiome

Celiac Disease Pathogenesis

What is a Gastric Bypass?

Gastric Carcinoma

Human Microbiome

What is Gastrointestinal Bleeding?

Gastritis Diagnosis

What is Vaginal Microbiome?

Gastric Varices - Signs and Symptoms

Symptoms and Diagnosis of Intestinal Malrotation

Is Dermatitis Herpetiformis Caused by Herpes?

Treatment and Prognosis for Intestinal Malrotation

Gastric Bypass Benefits

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Mechanism of Irritable Bowel Syndrome (IBS)

Gastroparesis Diagnosis

What does Sleeve Gastrectomy Involve?

Gastroparesis Epidemiology

Gut Microbiota

Self-Help for Irritable Bowel Syndrome (IBS)

Is There a Link Between Migraine and the Gut Microbiome?

Fermented Foods and Gut Health

Human Microbiome Project (HMP)

Gut-on-a-Chip to Model Coeliac Disease

Treatment of Irritable Bowel Syndrome

Microbiome-Host Cell Interactions

Dysbiosis and the Microbiome

What is Gastroenteritis?

Fecal Microbiota Transplant Technique

What is Gastroparesis?

Gastroparesis Treatments

Gastrointestinal Stromal Tumor (GIST) Causes

Effects of a Gluten-Free Diet on the Gut Microbiota

Gastroparesis Causes

How Does the Diet Impact Microbiota?

Oral Microbiota

What is Celiac Disease?

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Gastrointestinal Stromal Tumor (GIST) Treatment

What is Irritable Bowel Syndrome?

Dysbiosis and Aging

Irritable Bowel Syndrome (IBS) Psychological Therapies

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) and Diet

Microbiome and Cancer

Causes of Irritable Bowel Syndrome

Inflammatory Bowel Disease and Colorectal Cancer

Celiac Disease Diagnosis

Gastritis Symptoms

Microbiome and Disease

Low FODMAP Diet

Mesentery: a new organ?

Gastric Bypass Criteria

Gastrointestinal Disease and Skin Problems

Irritable Bowel Syndrome (IBS) and Exercise

Irritable Bowel Syndrome (IBS) Comorbidities

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Gastrointestinal Bleeding Symptoms

Alzheimer's Disease and the Microbiome

Parkinson's Disease and the Gut Microbiome

What is Gastroenterology?

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Gastroschisis Prognosis

Fecal Microbiota Transplant

Fecal Microbiota Transplant Regulation

Short-Chain Fatty Acids (SCFAs)

Diabetic Gastroparesis

What is Gastroschisis?

Antibiotics and the Microbiome

Does the Microbiome Interact with the Human Endocrine System?

Irritable Bowel Syndrome (IBS) Food Triggers

Irritable Bowel Syndrome (IBS) and Stress Response

Diagnosis of Irritable Bowel Syndrome

Gastrointestinal Bleeding Treatment

What is Gluten?

Latest Gastrointestinal Health News and Research

A child's gut microbiome may offer early clues to type 1 diabetes risk

Researchers tracking 887 children at high genetic risk of type 1 diabetes identified three distinct patterns of gut microbiome maturation during early childhood. One pattern was associated with substantially higher risk of islet autoantibody seroconversion or type 1 diabetes, while host genetic background altered the risk associated with another pattern.

23 Sep 2026

Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases

Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated signal transduction.

23 Sep 2026

Dietary changes can prevent Hirschsprung disease symptoms

A multi-institutional study led by researchers at Children's Hospital of Philadelphia (CHOP) discovered for the first time that dietary interventions might prevent inflammatory symptoms associated with Hirschsprung disease, a bowel motility disorder.

23 Sep 2026

Parental plastic exposure harms offspring through multiple biological routes

Microplastics and nanoplastics are increasingly found throughout aquatic environments, raising concern about whether these tiny particles can move from exposed parents into their offspring.

23 Sep 2026

Bedfont® brings hydrogen and methane breath testing to the global stage at UEG Week 2026

Bedfont® Scientific Limited, a world leader in breath analysis with 50 years of industry experience, is pleased to attend this year’s United European Gastroenterology (UEG) Week in Barcelona to showcase the innovative Gastrolyzer® range of devices.

From Bedfont® Scientific Ltd 23 Sep 2026

Could a parent’s hospital job shape a child’s nasal microbiome?

A pilot study of 37 families found that children with healthcare-worker parents had lower nasal microbial diversity, with the largest differences among children whose two parents worked in healthcare. Porphyromonas was significantly less abundant, while Neisseria showed a similar non-significant pattern, but the cross-sectional study cannot establish causality or determine whether these microbiota differences affect health.

23 Sep 2026

Higher ultra-processed food intake linked to multiple health risks

A higher ultra processed food (UPF) intake is linked to a heightened risk of several major chronic health issues, such as digestive diseases, high blood pressure, and metabolic syndrome/diabetes, as well as death, finds a pooled data analysis of the available evidence, published in the open access journal Family Medicine and Community Health.

22 Sep 2026

Study identifies B cells as drivers of immunotherapy-related colitis

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown role for B cells, which are adaptive immune cells, in triggering and sustaining colitis occurring as a side effect of immune checkpoint inhibitors, a widely used form of cancer immunotherapy.

22 Sep 2026

Garvan research reveals hidden inflammation behind high colon cancer risk

New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different.

22 Sep 2026

Stalled gut microbiome development triples risk for type 1 diabetes in children

Type 1 diabetes affects more than 9 million people worldwide, including 1.8 million children and adolescents.

21 Sep 2026

B cells may play a role in triggering immunotherapy-related colitis

18 Sep 2026

Persistent stigma creates barriers to modern HIV prevention methods

For decades, HIV (human immunodeficiency virus) has been surrounded by fear, misinformation and stigma.

18 Sep 2026

Innate immune system variations determine vaccine side effects

Redness and pain at the injection site, fever, fatigue or headaches: vaccines can cause side effects, but their frequency and severity vary considerably from person to person.

17 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Study defines early-onset cirrhosis caused by fatty liver disease

Researchers at University of California San Diego School of Medicine have published the first study to define early-onset cirrhosis caused by metabolic dysfunction-associated steatotic liver disease (MASLD), a condition known as fatty liver disease.

16 Sep 2026

Simple fecal test could help detect colorectal and pancreatic cancers

Gastrointestinal and pancreatobiliary cancers can be difficult to detect early, creating a need for practical, noninvasive approaches for early detection and risk assessment.

16 Sep 2026

Genetically modified bacteria create protective shield against Salmonella attacks

The mammalian gut microbiome is teeming with a delicate balance of bacteria and the viruses that keep them in check, called bacteriophages, or phages.

16 Sep 2026

Bacterial strains determine pneumonia and meningitis risk from air pollution

Air pollution leads to different risk of bacterial pneumonia, sepsis, and meningitis, depending on the subtype of bacteria a person has, new research suggests.

15 Sep 2026

Cockroaches have a reputation for surviving almost anything, but this diet proved deadly

A laboratory study tested how ultra-processed, unprocessed, and mixed diets affected survival in 127 lobster cockroaches, Nauphoeta cinerea. Cockroaches fed only ultra-processed foods had higher mortality than those given unprocessed or mixed diets, although the study could not determine whether processing, ingredients, nutrition, or differences in food intake caused the effect.

13 Sep 2026

People with ADHD face higher odds of gastrointestinal problems

University of Warwick researchers have analyzed data from over 1.9 million people across 23 studies and found that ADHD is linked to an almost 50% increase in overall gastrointestinal symptoms compared with people without ADHD The association was even stronger for specific problems: nearly double the odds of constipation, a 58% increase in irritable bowel syndrome, and more than four times the odds of encopresis (loss of bowel control).

10 Sep 2026