Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

How Does the Diet Impact Microbiota?

Celiac Disease Treatment

Irritable Bowel Syndrome (IBS) Research

Gastric Bypass Benefits

Do Serotonin and Antidepressants Affect the Microbiome?

Gastrointestinal Stromal Tumor Pathogenesis

Sarin Classification of Gastric Varices

Gastroparesis and Diet

Achievements of the Human Microbiome Project

Conjunctiva microbiota

Irritable Bowel Syndrome (IBS) and Exercise

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Malrotation of the Gastrointestinal Tract

Celiac Disease Symptoms

Oral Microbiota

Causes of Gastro-Esophageal Reflux Disease (GERD)

Irritable Bowel Syndrome (IBS) Food Triggers

Diabetic Gastroparesis

Short-Chain Fatty Acids (SCFAs)

High FODMAP Foods and Low FODMAP Food Alternatives

Gastric Varices - Signs and Symptoms

Gut Microbiota

Dermatitis Herpetiformis and Celiac Disease

What is Gastritis?

Gastroparesis Epidemiology

Gastroparesis Causes

What does Sleeve Gastrectomy Involve?

Gastrointestinal Disease and Skin Problems

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Gastroparesis Symptoms

Effects of a Gluten-Free Diet on the Gut Microbiota

Gastric Bypass Complications

Irritable Bowel Syndrome (IBS) and Diet

Human Microbiome

What is Celiac Disease?

Dysbiosis and Aging

Alzheimer's Disease and the Microbiome

Gastric Carcinoma

What is Irritable Bowel Syndrome?

Post-Infectious Irritable Bowel Syndrome

Low FODMAP Diet

Drug Metabolism and Microbiome

Gastritis Treatments

Fecal Microbiota Transplant Technique

FODMAPs and Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) Comorbidities

Irritable Bowel Syndrome (IBS) and Infections

Does Wheat Cause Gut Inflammation?

What is Ulcerative Colitis?

The Microbiome and Aging

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Microbiome-Host Cell Interactions

Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) Epidemiology

Fecal Microbiota Transplant Regulation

What is Gastroschisis?

Celiac Disease Screening

What is Vaginal Microbiome?

FODMAP Research

Dysbiosis and the Microbiome

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Microbiome and Cancer

Gastrointestinal Bleeding Symptoms

Genetics of Inflammatory Bowel Disease (IBD)

Self-Help for Irritable Bowel Syndrome (IBS)

Celiac Disease Diagnosis

Mesentery: a new organ?

What is Gastrointestinal Bleeding?

How to Recover Gut Health After Clostridium difficile Infection

What is Gastroparesis?

Symptoms and Diagnosis of Intestinal Malrotation

Irritable Bowel Syndrome (IBS) and Stress Response

Treatment and Prognosis for Intestinal Malrotation

Gastroparesis Treatments

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Does the Microbiome Interact with the Human Endocrine System?

Gastric Bypass Types

Inflammatory Bowel Disease and Colorectal Cancer

Probiotics and IBS

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Risk Factors for Small Intestinal Bacterial Overgrowth

Inflammatory Bowel Disease (IBD) in Pregnancy

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Fecal Microbiota Transplant

Treatment of Irritable Bowel Syndrome

Skin Microbiota

Causes of Irritable Bowel Syndrome

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Disease Susceptibility and the Microbiome

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Human Microbiome Project (HMP)

Microbiome and Disease

Gastroparesis Diagnosis

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Treatment of Gastric Varices

Gastritis Causes

Gastritis Symptoms

What is Gastroenterology?

Types of Gastrectomy

Parkinson's Disease and the Gut Microbiome

Crohn's Disease Cause

What is Gluten?

Gastrointestinal Stromal Tumor (GIST) Treatment

Gastrointestinal Bleeding Treatment

Gastrointestinal Stromal Tumor (GIST) Causes

After Gastric Bypass Surgery

What is Gastroenteritis?

Mechanism of Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) Psychological Therapies

Ulcerative Colitis Causes

Fermented Foods and Gut Health

Gastritis Diagnosis

Diagnosis of Irritable Bowel Syndrome

Gastric Varices

Antibiotics and the Microbiome

Irritable Bowel Syndrome (IBS) Prognosis

Gastric Bypass Criteria

Gastroschisis Prognosis

Celiac Disease Pathogenesis

Is There a Link Between Migraine and the Gut Microbiome?

Gut-on-a-Chip to Model Coeliac Disease

What is a Gastric Bypass?

Is Dermatitis Herpetiformis Caused by Herpes?

Gastroschisis Causes

Latest Gastrointestinal Health News and Research

Botanical prebiotics may steer skin microbes toward healthier balance

Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.

30 Jun 2026

Experts reframe steatotic liver disease as a dynamic continuum

The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof. Tacke from Charité - Universitätsmedizin Berlin argue that metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD) should not be regarded as rigid diagnostic categories, but rather as interconnected and evolving disease trajectories.

30 Jun 2026

Altering gut microbes could improve immunotherapy responses in liver cancer

Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering new hope where few options existed.

30 Jun 2026

Analysis shows artificial sweeteners may harm adult metabolism function

Since the first introduction of saccharin, an array of artificial and other non-nutritive (i.e., low-calorie or calorie-free) sweeteners have become ubiquitous in the US food supply.

30 Jun 2026

Breast milk sugars help shape infant gut microbiota during weaning

Research from DTU and Rigshospitalet shows that sugars in breast milk play an important role in the development of the gut microbiota, during weaning or transition from breast milk to solid food.

30 Jun 2026

Nerve stimulation methods provide safe relief for oropharyngeal dysphagia

Dysphagia, a severe comorbidity of many neurological diseases, often lacks targeted therapies. This critical review assessed the clinical effectiveness and safety of electrical stimulation of cranial nerves for treating dysphagia, including implantable (direct nerve stimulation), minimally invasive (pharyngeal electrical stimulation, PES), and non‑invasive (transcutaneous) approaches.

30 Jun 2026

Probiotic metabolite found to suppress melanoma tumor growth in mice

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance.

30 Jun 2026

Blood metabolism maps how lifestyle tracks function in cognitive aging

A new study used pathway-level blood metabolomics to identify lifestyle-associated metabolic patterns linked to physical, cognitive, and daily functional performance across CN, MCI, and AD. The findings suggest that diet- and activity-linked pathway signals span energy, amino acid, lipid, inflammatory, oxidative stress, and microbiome-related metabolism, but require independent and longitudinal validation.

29 Jun 2026

Scientists uncover immune mechanisms driving rare gastrointestinal disorder

A collaborative team led by Dr. Jingnan Li and Dr. Ji Li at Peking Union Medical College Hospital, together with Associate Professor Xiaohuan Guo at Tsinghua University and Academician Ye-Guang Chen at Tsinghua University School of Life Sciences, published a study in Volume 2, article number 28 of the journal Immunity & Inflammation on June 17, 2026.

26 Jun 2026

Yale study offers critical clues for future norovirus treatments

As the leading cause of viral gastroenteritis worldwide, norovirus is an all too familiar ailment. Its telltale digestive upset — not to mention its reputation for being notoriously contagious — has earned it the nicknames "winter vomiting bug" and "stomach flu."

26 Jun 2026

Breastfeeding linked to longer sleep duration in one year old infants

The World Health Organization (WHO) recommends exclusive breastfeeding for the first six months of life because of its many proven benefits, including protection against infections and support for healthy long-term development.

26 Jun 2026

New accessible multiplex imaging workflow advances spatial liver research

Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization and interactions within intact tissues.

26 Jun 2026

New project investigates gut microbiome for personalized bowel disease therapies

The gut microbiome plays an important role in inflammatory bowel disease. In the research project MikrobiomProCheck, researchers are investigating how microbiome data can in future be used for diagnostics, disease monitoring and personalized therapies.

26 Jun 2026

AI and multiomics reveal how gut bacteria trigger colon cancer

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

26 Jun 2026

Gut microbes emerge as potential players in estrogen-driven cancers

A new review maps how the endocrine-microbiome axis expands the estrobolome concept, showing that gut microbes may alter estrogen recycling, produce hormone-like metabolites, and shape inflammation and tissue environments in hormone-driven cancers. Human evidence remains mostly associative, so the authors call for causal models, longitudinal multi-omics, multi-kingdom profiling, and sex-stratified studies before microbiome-guided cancer strategies enter routine care.

25 Jun 2026

Scientists find link between bacterium in the gut ecosystem and lupus

Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, found a link between a bacterium in the gut microbiome, or ecosystem, and lupus, which could lead to more effective treatment of the disease, in a study published in Nature Communications.

25 Jun 2026

Blood metabolites reveal lifestyle links to brain health before dementia

Blood metabolome profiling in dementia-free middle-aged adults linked 14 metabolites to cognition and 22 metabolites to MRI markers of brain health. Lifestyle, clinical factors, medication use and gut microbiota appeared to shape many of these metabolites, with ergothioneine emerging as a notable cognition-linked signal.

25 Jun 2026

Scientists find a universal gut microbiome pattern linked to colorectal cancer

Researchers analyzed 6,779 stool microbiome profiles and 906 tissue samples to identify a colorectal cancer microbial signature that remained consistent across age groups, populations, and sequencing methods. The signature aligned with tumor-resident microbes, showed weaker detection for adenomas, and was inversely associated with dietary fiber intake.

25 Jun 2026

Blueberries may boost children's memory and mood

Research suggests blueberry compounds could enhance mood and cognitive function in children, yet stronger evidence is required for clinical recommendations.

25 Jun 2026

European project receives €15 million to study phage-based therapies

Bacteria are becoming increasingly resistant to antibiotics. One alternative is treatment with viruses that exclusively infect bacteria, known as phages.

25 Jun 2026