Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

Gastrointestinal Bleeding Treatment

Microbiome and Disease

Gastritis Causes

What is Ulcerative Colitis?

Dysbiosis and the Microbiome

Gut Microbiota

Is Dermatitis Herpetiformis Caused by Herpes?

What is Gluten?

What is Gastritis?

Inflammatory Bowel Disease and Colorectal Cancer

Gastric Carcinoma

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Gastroparesis Causes

Gastroparesis Treatments

Effects of a Gluten-Free Diet on the Gut Microbiota

Achievements of the Human Microbiome Project

Ulcerative Colitis Causes

Gastric Varices - Signs and Symptoms

How to Recover Gut Health After Clostridium difficile Infection

Crohn's Disease Cause

Human Microbiome

Is There a Link Between Migraine and the Gut Microbiome?

Types of Gastrectomy

Low FODMAP Diet

Gastroparesis Epidemiology

Dysbiosis and Aging

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

Celiac Disease Diagnosis

Fecal Microbiota Transplant Technique

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Gastritis Diagnosis

Gastroschisis Causes

Oral Microbiota

Mechanism of Irritable Bowel Syndrome (IBS)

Microbiome and Cancer

Does Wheat Cause Gut Inflammation?

Dermatitis Herpetiformis and Celiac Disease

Treatment of Gastric Varices

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

The Microbiome and Aging

Conjunctiva microbiota

Gastroparesis and Diet

After Gastric Bypass Surgery

FODMAPs and Irritable Bowel Syndrome (IBS)

What is Gastroenteritis?

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Celiac Disease Symptoms

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Causes of Gastro-Esophageal Reflux Disease (GERD)

Diabetic Gastroparesis

What is Vaginal Microbiome?

Diagnosis of Irritable Bowel Syndrome

What is Gastroenterology?

What is Gastroschisis?

Irritable Bowel Syndrome (IBS) Food Triggers

Irritable Bowel Syndrome (IBS) and Infections

Gastric Varices

Gastric Bypass Types

Irritable Bowel Syndrome (IBS) Epidemiology

Gastrointestinal Stromal Tumor (GIST) Treatment

Alzheimer's Disease and the Microbiome

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Inflammatory Bowel Disease (IBD) in Pregnancy

Symptoms of Irritable Bowel Syndrome

Causes of Irritable Bowel Syndrome

Gastric Bypass Complications

Drug Metabolism and Microbiome

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Celiac Disease Treatment

Sarin Classification of Gastric Varices

Do Serotonin and Antidepressants Affect the Microbiome?

What is Gastroparesis?

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Celiac Disease Pathogenesis

Gastrointestinal Disease and Skin Problems

Treatment and Prognosis for Intestinal Malrotation

Irritable Bowel Syndrome (IBS) Psychological Therapies

What is Celiac Disease?

Irritable Bowel Syndrome (IBS) Comorbidities

Gastroparesis Diagnosis

What is Gastrointestinal Bleeding?

What is a Gastric Bypass?

Risk Factors for Small Intestinal Bacterial Overgrowth

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Gastrointestinal Stromal Tumor Pathogenesis

What is Irritable Bowel Syndrome?

Disease Susceptibility and the Microbiome

Skin Microbiota

Gastroschisis Prognosis

Genetics of Inflammatory Bowel Disease (IBD)

Irritable Bowel Syndrome (IBS) Prognosis

Does the Microbiome Interact with the Human Endocrine System?

Gastritis Treatments

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Gastric Bypass Criteria

Malrotation of the Gastrointestinal Tract

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Irritable Bowel Syndrome (IBS) and Exercise

Fecal Microbiota Transplant Regulation

Fermented Foods and Gut Health

Parkinson's Disease and the Gut Microbiome

Celiac Disease Screening

How Does the Diet Impact Microbiota?

Fecal Microbiota Transplant

Gastritis Symptoms

Human Microbiome Project (HMP)

Antibiotics and the Microbiome

Microbiome-Host Cell Interactions

What does Sleeve Gastrectomy Involve?

Gastroparesis Symptoms

Gastric Bypass Benefits

Gastrointestinal Stromal Tumor (GIST) Causes

Gut-on-a-Chip to Model Coeliac Disease

FODMAP Research

High FODMAP Foods and Low FODMAP Food Alternatives

Irritable Bowel Syndrome (IBS) Research

Treatment of Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) and Diet

Self-Help for Irritable Bowel Syndrome (IBS)

Symptoms and Diagnosis of Intestinal Malrotation

Irritable Bowel Syndrome (IBS) and Stress Response

Post-Infectious Irritable Bowel Syndrome

Gastrointestinal Bleeding Symptoms

Short-Chain Fatty Acids (SCFAs)

Probiotics and IBS

Mesentery: a new organ?

Latest Gastrointestinal Health News and Research

Most Americans would consider swapping classic Super Bowl party fare for plant-based options, poll finds

It is estimated that Americans will consume 1.48 billion chicken wings during the Super Bowl, but a new Physicians Committee for Responsible Medicine/Morning Consult poll finds that most Americans, 56%, would consider trying a plant-based alternative such as Baked Buffalo Cauliflower Bites while watching the New England Patriots and Seattle Seahawks on Feb. 8.

31 Jan 2026

Turning everyday eggs into powerful nutrient delivery systems

Eggs as functional foods: this review explores enrichment techniques that enhance nutrient bioavailability and support health through precision nutrition.

30 Jan 2026

Gut microbiome may be a central player in the body's response to cancer

A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer, according to researchers at Weill Cornell Medicine.

29 Jan 2026

Study reveals a link between oral microbiota and cognitive performance in schizophrenia

An association between oral microbiota and cognitive performance in schizophrenia has been reported by researchers at Science Tokyo.

29 Jan 2026

Poop pills could help cancer patients respond to immunotherapy while reducing toxic side effects

Fecal microbiota transplants (FMT), can dramatically improve cancer treatment, suggest two groundbreaking studies published in the prestigious Nature Medicine journal.

28 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

How modern lifestyles reprogram the gut microbiome and shape disease risk

Modern lifestyle factors such as circadian disruption, sleep deprivation, stress, and exercise reshape the gut bacteriome and its metabolic outputs. These microbiome changes are linked to immune, metabolic, and cancer-related pathways, largely through evidence from animal models and observational human studies.

27 Jan 2026

Why eating more oats can rapidly reduce cholesterol levels

Oat consumption boosts gut microbiota-derived phenolic metabolites, driving cholesterol-lowering effects and improving lipid metabolism in metabolic syndrome.

27 Jan 2026

Olive oil type matters for cognition and gut health in older adults

Higher intake of virgin and total olive oil was associated with modest but significant improvements in cognitive performance over two years in older adults with metabolic syndrome. These associations were partly linked to gut microbiota composition, with specific taxa such as Adlercreutzia contributing a small mediating effect.

26 Jan 2026

Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

Micro- and nanoplastics are increasingly detected in human tissues, including the brain, and experimental evidence suggests they can interact with biological pathways central to Parkinson’s disease pathology. This review synthesises mechanistic data indicating that plastic particles may influence protein aggregation, neuroinflammation, mitochondrial dysfunction, and the gut–brain axis, while emphasising the need for prospective human studies.

26 Jan 2026

Evidence links gut microbiome changes to Alzheimer’s progression

Human studies consistently report gut microbiome differences in mild cognitive impairment and Alzheimer’s disease, but findings vary widely by cohort, methods, and taxa. Heterogeneity and limited longitudinal data prevent causal inference, highlighting the need for functional profiling and well-designed intervention trials.

25 Jan 2026

Microbiome differences distinguish preterm infants with parenteral nutrition-associated cholestasis

24 Jan 2026

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD).

24 Jan 2026

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

24 Jan 2026