Gastrointestinal Health

This hub offers a comprehensive resource on gastrointestinal health, digestive diseases, and the human microbiome, drawing together authoritative articles on basic science, clinical management, and emerging research. The collection addresses the pathophysiology, diagnosis, and treatment of major gastrointestinal disorders, including irritable bowel syndrome, celiac disease, inflammatory bowel disease, and gastroesophageal reflux, while also exploring surgical, dietary, and pharmacological interventions. Special emphasis is given to the role of the gut microbiome in health and disease, including its influence on immunity, metabolism, neurological function, and response to therapy. Readers will also find up-to-date insights into microbiome-related interventions, such as fecal microbiota transplantation, as well as practical guidance for dietary management and prevention. This hub serves as a trusted reference for clinicians, researchers, and individuals seeking an evidence-based understanding of digestive and microbiome science.

Can you Treat a Food Allergy by Altering the Gut Microbiome?

There is a relationship between gut microbiome and allergy which may allow some children to outgrow their food allergy.

How Does the Diet Impact Microbiota?

Fecal Microbiota Transplant Technique

Skin Microbiota

Irritable Bowel Syndrome (IBS) Food Triggers

Gastroparesis Diagnosis

Symptoms of Gastro-Esophageal Reflux Disease (GERD)

Microbiome-Host Cell Interactions

Human Microbiome Project (HMP)

Symptoms and Diagnosis of Intestinal Malrotation

What is Gastroenteritis?

Diabetic Gastroparesis

See more featured articles »

Fermented Foods and Gut Health

What is a Gastric Bypass?

What does Sleeve Gastrectomy Involve?

Celiac Disease Screening

Gastrointestinal Disease and Skin Problems

What is Gastroenterology?

FODMAPs and Irritable Bowel Syndrome (IBS)

Crohn's Disease Cause

Causes of Gastro-Esophageal Reflux Disease (GERD)

Gastrointestinal Stromal Tumor (GIST) Causes

Celiac Disease Pathogenesis

Symptoms of Irritable Bowel Syndrome

Drug Metabolism and Microbiome

Probiotics and IBS

Sarin Classification of Gastric Varices

FODMAP Research

Functional Gastrointestinal Disorders: Integrating Physiological and Psychological Approaches

Post-Infectious Irritable Bowel Syndrome

Microbiome and Disease

What is Gastritis?

Irritable Bowel Syndrome (IBS) and Stress Response

ERCP (Endoscopic Retrograde Cholangiopancreatography) Overview

Gastritis Causes

Gastric Varices

Gastric Varices - Signs and Symptoms

Dysbiosis and Aging

The Microbiome and Aging

Mechanism of Irritable Bowel Syndrome (IBS)

Gastrointestinal Bleeding Symptoms

What is Irritable Bowel Syndrome?

Irritable Bowel Syndrome (IBS) Differential Diagnosis

Gastric Bypass Complications

Alzheimer's Disease and the Microbiome

Treatment and Prognosis for Intestinal Malrotation

What is Ulcerative Colitis?

Dermatitis Herpetiformis and Celiac Disease

Short-Chain Fatty Acids (SCFAs)

Irritable Bowel Syndrome (IBS) Comorbidities

Malrotation of the Gastrointestinal Tract

Fecal Microbiota Transplant Regulation

Gastroparesis Treatments

What is Gastroparesis?

What is Vaginal Microbiome?

Gut-on-a-Chip to Model Coeliac Disease

Treatment of Irritable Bowel Syndrome

Conjunctiva microbiota

Risk Factors for Small Intestinal Bacterial Overgrowth

How to Recover Gut Health After Clostridium difficile Infection

Gastroparesis Epidemiology

Inflammatory Bowel Disease (IBD) in Pregnancy

Dysbiosis and the Microbiome

Irritable Bowel Syndrome (IBS) and Infections

What is Gastroschisis?

Disease Susceptibility and the Microbiome

Irritable Bowel Syndrome (IBS) and Exercise

Types of Gastrectomy

What is Gastrointestinal Bleeding?

Is Dermatitis Herpetiformis Caused by Herpes?

Irritable Bowel Syndrome (IBS) and Psychiatric Illness

Gastric Bypass Criteria

Gastrointestinal Stromal Tumor (GIST) Diagnosis

Treatment of Gastro-Esophageal Reflux Disease (GERD)

Gastroparesis Causes

Achievements of the Human Microbiome Project

Irritable Bowel Syndrome (IBS) Research

Diagnosis of Irritable Bowel Syndrome

Fecal Microbiota Transplant

Does Wheat Cause Gut Inflammation?

Gastrointestinal Stromal Tumor (GIST) Treatment

Gastritis Symptoms

Gastroparesis Symptoms

Oral Microbiota

Celiac Disease Symptoms

Celiac Disease Diagnosis

Effects of a Gluten-Free Diet on the Gut Microbiota

Gastrointestinal Bleeding Treatment

Gastritis Treatments

Microbiome and Cancer

Irritable Bowel Syndrome (IBS) Psychological Therapies

Gastroparesis and Diet

Causes of Bleeding in the Upper and Lower Gastrointestinal Tract

After Gastric Bypass Surgery

Celiac Disease Treatment

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Inflammatory Bowel Disease and Colorectal Cancer

Irritable Bowel Syndrome (IBS) Prognosis

Treatment of Gastric Varices

Antibiotics and the Microbiome

What is Gluten?

Genetics of Inflammatory Bowel Disease (IBD)

Is There a Link Between Migraine and the Gut Microbiome?

Causes of Irritable Bowel Syndrome

What is Celiac Disease?

Gastrointestinal Stromal Tumor Pathogenesis

High FODMAP Foods and Low FODMAP Food Alternatives

Irritable Bowel Syndrome (IBS) Epidemiology

Irritable Bowel Syndrome (IBS) and Diet

Self-Help for Irritable Bowel Syndrome (IBS)

Gastric Bypass Types

Mesentery: a new organ?

Parkinson's Disease and the Gut Microbiome

Gastrointestinal Stromal Tumor (GIST) Signs and Symptoms

Gastroschisis Prognosis

Does the Microbiome Interact with the Human Endocrine System?

Ulcerative Colitis Causes

Low FODMAP Diet

Irritable Bowel Syndrome (IBS) and Fibromyalgia

Gastric Bypass Benefits

Gut Microbiota

Gastroschisis Causes

Gastritis Diagnosis

Diagnosis of Gastro-Esophageal Reflux Disease (GERD)

Gastric Carcinoma

Do Serotonin and Antidepressants Affect the Microbiome?

Human Microbiome

Latest Gastrointestinal Health News and Research

Gut nervous system controls intestinal barrier and allergy risk

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.

25 Nov 2025

Unraveling the mycobiome's role in cancer

A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response.

25 Nov 2025

Using a prebiotic after traumatic brain injury may help reduce impulsive behavior

Using a prebiotic to influence bacterial activity in the gut after a traumatic brain injury may help reduce impulsive behavior, one of the common symptoms to follow a moderate blow to the head, a new study in rats suggests.

25 Nov 2025

Gut neurons control immunity attack or repair

Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the immune system should go into attack mode or start repairing tissue.

24 Nov 2025

Researchers uncover a new way to understand how children fare after liver transplantation

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a new way to understand how children fare after liver transplantation: by focusing not on medical test results, but on how differently parents and children perceive the child's well-being.

24 Nov 2025

Experts launch digital hub to transform bowel cancer prevention and care

World-leading experts have launched an online platform to enable the public to shape the future of bowel cancer research and patient care.

22 Nov 2025

Study shows gluten sensitivity is driven by gut–brain interactions rather than gluten

A landmark study has revealed that gluten sensitivity, which affects approximately 10 per cent of the global population, is not actually about gluten but part of the way the gut and brain interact.

21 Nov 2025

AGA issues updated guidance for pharmacologic treatment of moderate-to-severe Crohn's disease

The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn's disease.

20 Nov 2025

New collection of bacteria-eating viruses can be effective against Klebsiella strains

Potential treatments for one of the world's most dangerous hospital superbugs have been found in a surprising location - hospital toilets.

20 Nov 2025

UK Biobank releases the world’s largest metabolomic dataset for disease research

UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by our bodies as we go about our lives – in half a million volunteers.

20 Nov 2025

Innovative new tool helps understand how gut microbes interact to influence health

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

20 Nov 2025

Global experts map out the practical steps that help extend life expectancy

The 1st World Longevity Summit in Kyotango, Japan brought together global experts to share advances in aging biology, lifestyle medicine, and community-based strategies for healthy longevity. Its joint declaration identified four pillars – social connection, plant-based diets, daily activity, and gratitude with purpose – as core foundations for extending healthy life expectancy worldwide.

19 Nov 2025

New prognostic tool can predict transplant needs in drug-induced liver injury patients

A newly developed tool, called the DILI-Inpt prognostic score, can predict patients with drug-induced liver injury who are unlikely to survive without a liver transplant.

19 Nov 2025

Oral microsphere pills can detect markers of gastrointestinal disease

Move over, colonoscopies - researchers report in ACS Sensors that they've developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease.

19 Nov 2025

Lean beef fits safely into a Mediterranean diet without raising heart disease risk

Eating moderate amounts of lean beef as part of a Mediterranean diet does not increase an emerging risk factor for cardiovascular disease, according to a new study by an interdisciplinary research team at Penn State.

19 Nov 2025

Gut immune cells follow an atypical pathway to provide long-lasting antiviral protection

A new study led by University of Toronto researchers has shown that immune cells in the gut follow an atypical pathway to produce antibodies that provide long-term protection against viruses.

17 Nov 2025

Gut microbes may fuel allergic rhinitis symptoms

The study identifies gut microbiome alterations in allergic rhinitis, suggesting a gut-nose axis that could inform new treatment approaches for this condition.

17 Nov 2025

Are mushrooms more than a low-calorie food? New analysis explains their hidden advantages

Whole mushroom consumption shows consistent benefits for cardiometabolic health, lowering triglycerides in self-chosen diets and improving fasting glucose in a single healthy dietary pattern trial. Early evidence also suggests increases in salivary IgA and possible blood pressure improvements, with no adverse biomarker effects reported.

16 Nov 2025

Unexpected traces of bacteria found within brain tumors

Researchers at The University of Texas MD Anderson Cancer Center have uncovered unexpected traces of bacteria within brain tumors.

14 Nov 2025

Scientists debunk gut microbiome-autism connection

There's no scientific evidence that the gut microbiome causes autism, a group of scientists argue in an opinion paper publishing November 13 in the Cell Press journal Neuron.

13 Nov 2025