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Research finds persistent prescribing of risky medications to older adults with dementia

Despite years of clinical guidelines warning against the practice, one in four Medicare beneficiaries with dementia is prescribed brain-altering medications linked to falls, confusion, and hospitalization, according to new research to be published January 12 in the peer-reviewed journal JAMA.

12 Jan 2026

Discovery lays foundation for understanding how the cell senses membrane injuries

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell.

12 Jan 2026

Study shows biosynthetic method to make low-calorie sugar substitute

From saccharin in the 19th century to stevia and monk fruit in the 21st, researchers and the food industry have long sought a sweetener that delivers the taste of sugar without its drawbacks-excess calories, tooth decay, and heightened risk for obesity, insulin resistance, and diabetes.

12 Jan 2026

New publication describes the chemical journey of non-hormonal male birth control pill

A newly published manuscript authored by Dr. Gunda Georg, YourChoice Therapeutics and Columbia University Medical Center describes the chemical journey of YCT-529, a non-hormonal male birth control pill, and the promising molecular science behind it.

12 Jan 2026

One thousand days of conflict push Sudan’s health system toward collapse

Today, the conflict in Sudan reaches its 1000th day, with over 20 million people requiring health assistance and 21 million desperately needing food.

12 Jan 2026

Brain immune cells drive persistent negative emotions after repeated binge drinking

New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying driver of prolonged negative feelings caused by repeated, sustained binge drinking (binge exposure).

12 Jan 2026

Gene regulators could restore the aging body's ability to self-repair

As we age, we don't recover from injury or illness like we did when we were young. But new research from UCSF has found gene regulators - proteins that turn genes on and off - that could restore the aging body's ability to self-repair.

12 Jan 2026

Study identifies gene protecting the maternal heart during pregnancy

Scientists at The Lundquist Institute for Biomedical Innovation have identified a previously unknown molecular safeguard that protects the heart during pregnancy, shedding new light on the causes of peripartum cardiomyopathy (PPCM), a rare and life-threatening form of pregnancy-related heart failure.

12 Jan 2026

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for triple‑negative breast cancer (TNBC), the most aggressive subtype of breast cancer.

12 Jan 2026

Two harmful gene variants can combine to restore normal protein function

In a groundbreaking study published in the in Proceedings of the National Academy of Sciences (PNAS), scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease.

12 Jan 2026

Gut bacteria protect mice from deadly secondary pneumonia after influenza

Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

12 Jan 2026

Rare sugars activate metabolic signaling to reduce alcohol consumption in mice

While investigating the FGF21-oxytocin-dopamine system, a mechanism that regulates sugar appetite, a team of researchers at Kyoto University noticed reports suggesting that the protein FGF21 may regulate alcohol ingestion.

12 Jan 2026

Analysis reveals why head and neck cancer clinical trials end early

Head and neck cancer trials are frequently derailed before they can deliver answers. A new analysis suggests that the most common reasons are sponsor decisions related to safety or effectiveness and poor patient recruitment.

12 Jan 2026

Trial finds no benefit of anti-inflammatory therapy in trachomatous trichiasis surgery

John Kempen, MD, MPH, PhD, MHS, Director of Epidemiology for Ophthalmology at Mass Eye and Ear and Harvard Medical School, is the lead author of a paper published in The Lancet Global Health, "Evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery (FLAME): a parallel, double-blind, randomised controlled field trial in the Jimma Zone, Ethiopia."

12 Jan 2026

Burn pit smoke exposure leaves lasting carbon particles in veterans’ lungs

A new study led by researchers at National Jewish Health provides quantitative evidence linking burn pit smoke exposure during military deployment to increases in harmful carbon-based particles in the lungs of post-9/11 veterans with distal lung disease.

12 Jan 2026

New eye injection restores sight in untreatable hypotony

A new study demonstrates the effectiveness of a widely-used eye injection to manage the previously untreatable rare condition, hypotony, in a project by clinical researchers at University College London (UCL) and Moorfields Eye Hospital.

12 Jan 2026

Digital twin technology guides personalized treatment for brain cancer patients

A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.

12 Jan 2026

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

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Medical News

Research finds persistent prescribing of risky medications to older adults with dementia

Discovery lays foundation for understanding how the cell senses membrane injuries

Study shows biosynthetic method to make low-calorie sugar substitute

New publication describes the chemical journey of non-hormonal male birth control pill

One thousand days of conflict push Sudan’s health system toward collapse

Brain immune cells drive persistent negative emotions after repeated binge drinking

Gene regulators could restore the aging body's ability to self-repair

Study identifies gene protecting the maternal heart during pregnancy

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Two harmful gene variants can combine to restore normal protein function

Gut bacteria protect mice from deadly secondary pneumonia after influenza

Rare sugars activate metabolic signaling to reduce alcohol consumption in mice

Analysis reveals why head and neck cancer clinical trials end early

Trial finds no benefit of anti-inflammatory therapy in trachomatous trichiasis surgery

Burn pit smoke exposure leaves lasting carbon particles in veterans’ lungs

New eye injection restores sight in untreatable hypotony

Digital twin technology guides personalized treatment for brain cancer patients

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

Digital interventions for alcohol and cannabis use among young adults show potential to reduce harms

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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