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Genetic variants may reduce effectiveness of popular diabetes drugs

More than a quarter of people with Type 2 diabetes take GLP-1 receptor agonists, but the popular diabetes drugs might not work as well for people who have certain genetic variants, according to a new study by Stanford Medicine scientists and their collaborators.

12 Apr 2026

Weight gain timing affects long-term health outcomes

When in life we gain weight can have a significant impact on our health many years later. In a study involving over 600,000 people, researchers at Lund University in Sweden have investigated how changes in weight between the ages of 17 and 60 are linked to the risk of dying from various diseases

11 Apr 2026

Letrozole monotherapy falls short in ovarian cancer clinical trial

Late breaking results from the phase III NRG GY019 trial indicate that letrozole monotherapy (L) did not demonstrate non inferiority to paclitaxel/carboplatin followed by letrozole (PC/L) for progression free survival (PFS) in patients with newly diagnosed stage II-IV low grade serous carcinoma of the ovary or peritoneum.

11 Apr 2026

Nanodisc technology improves study of viral proteins for vaccines

Viruses are masters at invading our cells thanks to specialized proteins that coat their surfaces. When scientists design vaccines, they often create versions of these viral surface proteins to study how our immune systems might respond.

11 Apr 2026

Study links COVID-19 infection to increased lung cancer risk

New findings from researchers at the Marshall University Joan C. Edwards School of Medicine and The Hebrew University of Jerusalem have identified a potential association between COVID-19 and increased lung cancer risk, driven by underlying biological mechanisms in the lung.

11 Apr 2026

New target CD43 may improve leukemia immunotherapy outcomes

Macrophages, much like Alice of "Alice in Wonderland," recognize and consume tumor cells that display "eat me" surface markers.

11 Apr 2026

Mezagitamab shows promise in treating immune thrombocytopenia patients

Results from a phase 2 clinical trial designed and overseen by researchers at Mass General Brigham Cancer Institute show that the investigational medication mezagitamab can effectively boost platelet counts in patients with immune thrombocytopenia (ITP), an autoimmune disease characterized by elevated platelet destruction and reduced platelet production that increases bleeding risk and compromises quality of life.

11 Apr 2026

Study uncovers key structure in fatal Borna disease virus 1

Cases of Borna disease virus 1, or BoDV-1, are extremely rare in humans, but in those who develop disease the outcome is severe, almost always resulting in fatal encephalitis or inflammation in the brain.

11 Apr 2026

Maternal signals help synchronize babies’ circadian rhythms before birth

Humans and most other organisms have internal biological clocks that track the daily cycle of sunrise and sunset. These clocks help time our sleep, metabolism and other essential body functions over the course of a day, creating daily patterns called circadian rhythms.

11 Apr 2026

New project aims to improve aggressive breast cancer diagnosis

Breast cancer is the most common form of cancer in women. According to the World Health Organization, in 2022, around 2.3 million women were diagnosed with breast cancer, and the disease caused about 670,000 deaths worldwide.

11 Apr 2026

Study reveals why immunotherapy fails in pancreatic cancer

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer - and identified a promising strategy to overcome that resistance.

11 Apr 2026

Challenging compulsory sex-marking to rethink gender norms and autonomy

Do our norms around sex presentation uphold a constrictive gender regime? In a new article in Ethics, Ophelia Vedder writes that the abolition of hegemonic gender roles must involve the elimination of "compulsory sex-marking," or the coercive social practice of signaling sexual identity through conventional means like clothes, hairstyles, and personal pronouns.

11 Apr 2026

Damon Runyon supports young scientists driving cancer research innovation

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

11 Apr 2026

Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to therapy due to their innate capacity for self-renewal and differentiation.

11 Apr 2026

Man steps forward to donate kidney to unknown teen

Tim Fitzpatrick was at home on Long Island when he saw a local news story about a 13-year-old boy in need of a kidney transplant.

11 Apr 2026

Study reveals immune aging differs significantly between men and women

Statistics show clear differences in the population's immune system according to sex: men are more susceptible to infections and cancers, while women have stronger immune responses, which translate, for example, into better responses to vaccines.

11 Apr 2026

Enriched environments improve stroke recovery and reduce brain inflammation

Stroke is one of the leading causes of death worldwide. Its recovery is often challenging as most of the stroke survivors remain chronically disabled, with motor deficits affecting a significant percentage of patients.

11 Apr 2026

Alligator Bioscience provides an update on mitazalimab

Alligator Bioscience, a clinical-stage biotechnology company developing tumor-directed immuno-oncology antibody drugs, today provided a brief update regarding mitazalimab.

From Alligator Bioscience 11 Apr 2026

New research leads to increased understanding of longevity gains in the United States

A new study co-authored by two University of Wisconsin–Madison professors suggests longevity gains across all states and regions for people born between 1941 and 2000, in contrast to previous estimates suggesting a century of stagnation or even declines in parts of the South.

10 Apr 2026

Brain pathways combine memory and reward to guide behavior

New research from the University of Maryland, Baltimore County (UMBC) reveals how two different parts of the brain's memory center team up in a key reward region to help mice-and likely humans-combine memories of places and contexts with the drive to pursue rewards.

10 Apr 2026