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Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Microbiome differences distinguish preterm infants with parenteral nutrition-associated cholestasis

24 Jan 2026

Colorblindness linked to delayed bladder cancer detection and higher mortality

Recognizing the sight of blood in urine, the most common first sign of bladder cancer, is often the impetus that leads people to a diagnosis.

24 Jan 2026

Firefighter protective gear restricts movement and may increase injury risk

When firefighters respond to an emergency, the gear they wear to protect themselves can also create challenges that could jeopardize their performance and safety.

24 Jan 2026

Selective inhibition of cPLA2 shows promise against Alzheimer's-related brain inflammation

A multidisciplinary USC research team has identified new compounds that may target a key driver of brain inflammation linked to Alzheimer's disease. Their research just published in the Nature publication npj Drug Discovery.

24 Jan 2026

Large multi-ancestry study expands understanding of schizophrenia genetics

A landmark study led by researchers with the Department of Veterans Affairs has uncovered new genetic insights into schizophrenia by analyzing data from ancestrally diverse populations, including African Americans, through the Million Veteran Program (MVP) and Cooperative Studies Program (CSP).

24 Jan 2026

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD).

24 Jan 2026

Three dimensional dataset transforms emergency medical training and robotic assistance

Researchers from Tianjin University have introduced the Emergency Medical Procedures 3D Dataset (EMP3D), a pioneering resource that captures the intricate movements of medical professionals during life-saving interventions with unprecedented precision.

24 Jan 2026

Experimental study reveals advanced episodic memory replay in rats

In a new study Indiana University researchers observed episodic memory in rats to a degree never documented before, suggesting that rats can serve as a model for complex cognitive processes often considered exclusively human.

24 Jan 2026

Orphan noncoding RNAs define cancer identity and enable blood-based monitoring

We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue.

24 Jan 2026

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

24 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Shared genetic architecture links schizophrenia with hemispheric white matter microstructure

Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in adolescence or early adulthood and characterized by hallucinations, delusions, disorganized thinking, and cognitive impairments; while its etiology remains elusive, genetic factors are widely recognized as fundamental, and GWAS have identified over 200 genome-wide significant loci.

24 Jan 2026

WHO Member States advance negotiations on the Pathogen Access and Benefit‑Sharing system

The World Health Organization (WHO) Member States this week advanced their negotiations on the Pathogen Access and Benefit‑Sharing (PABS) system in a resumed session of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement.

24 Jan 2026

Tips for staying heart-safe during cold weather

While grocery store shelves may be empty, firewood piles filled and cell phones charged, there may be a few more items to check off on your prep list for the upcoming winter storms.

24 Jan 2026

New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease

An international task force of medical experts recently proposed major revisions to the way doctors measure treatment success for a common–and often severe–skin complication of stem cell transplantation.

24 Jan 2026

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Prediabetes is an extremely heterogeneous metabolic disorder. Scientists from several partner institutes of the German Center for Diabetes Research (DZD) have now used artificial intelligence (AI) to identify epigenetic markers that indicate an elevated risk of complications.

24 Jan 2026

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Metastatic urothelial carcinoma has a poor prognosis: ~50% of muscle-invasive bladder cancer progresses to metastasis, and the 5-year survival for advanced/metastatic disease is <10%.

24 Jan 2026

Short-term oatmeal diet improves cholesterol and metabolic health markers

A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by a trial by the University of Bonn, which has now been published in the journal Nature Communications.

23 Jan 2026

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company driven by generative artificial intelligence (AI), today announced that ISM8969, an orally available NLRP3 inhibitor targeting inflammation and neurodegenerative disorders, has recently received investigational new drug (IND) clearance from the U.S. Food and Drug Administration (FDA), intended for the treatment of Parkinson's Disease.

23 Jan 2026

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Medical News

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Microbiome differences distinguish preterm infants with parenteral nutrition-associated cholestasis

Colorblindness linked to delayed bladder cancer detection and higher mortality

Firefighter protective gear restricts movement and may increase injury risk

Selective inhibition of cPLA2 shows promise against Alzheimer's-related brain inflammation

Large multi-ancestry study expands understanding of schizophrenia genetics

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Three dimensional dataset transforms emergency medical training and robotic assistance

Experimental study reveals advanced episodic memory replay in rats

Orphan noncoding RNAs define cancer identity and enable blood-based monitoring

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Shared genetic architecture links schizophrenia with hemispheric white matter microstructure

WHO Member States advance negotiations on the Pathogen Access and Benefit‑Sharing system

Tips for staying heart-safe during cold weather

New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Short-term oatmeal diet improves cholesterol and metabolic health markers

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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