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Oral GLP-1 drug elecoglipron helps adults lose up to 11.8% body weight

Once-daily oral elecoglipron produced dose-dependent weight loss in adults with obesity or overweight without diabetes, with mean reductions reaching 10.5% at 26 weeks and 11.8% at 36 weeks in the highest-dose weekly-titration group. The phase 2 trial found no evidence of a weight-loss plateau by 36 weeks, while gastrointestinal adverse events were common but generally manageable.

11 Jun 2026

Increased stress, reduced sleep alter brain structure and function in children

A new study suggests that variables linked to socioeconomic status (SES) – such as increased stress and reduced sleep – have strong relationships to brain structure and function in children.

11 Jun 2026

FDA accepts immunotherapy drug for review in colon cancer treatment

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

11 Jun 2026

Interspecies blastocyst complementation generates generates rat-derived kidneys in mice

Kidney transplantation remains the most effective treatment for end-stage kidney disease, yet a severe shortage of donor organs continues to limit access for millions of patients worldwide.

11 Jun 2026

Brain histamine neurons control moment-to-moment memory accessibility

The same memory can feel vivid and accessible one moment, yet stubbornly out of reach the next - even when the memory itself remains intact.

11 Jun 2026

Amsterdam UMC researchers overturn long-standing biological pacemaker dogma

Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field.

11 Jun 2026

Researchers track how chronic wasting disease spreads to other species

Chronic wasting disease (CWD) is generally associated with animals. But a new study by researchers from the University of Calgary and international collaborators explored the potential for CWD to spread from deer, elk and other cervid (hooved, plant-eating) animals to other species.

11 Jun 2026

Study: Employer points systems drive workers to show up sick

A new study finds that employer points systems, which penalize workers for absences regardless of the reason, are strongly associated with presenteeism, the practice of showing up to work while sick, and that these systems undermine the public health benefits of paid sick leave laws even in jurisdictions where such protections are on the books.

11 Jun 2026

Metformin reduces long COVID risk according to ACTIV-6 clinical trial

New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed long COVID when started during acute COVID-19 infection.

11 Jun 2026

Texas Children’s Hospital and Baylor researcher joins ARIA IMPACT Network to advance autism therapies

Dr. Jimmy Holder, associate professor in pediatrics at Baylor College of Medicine and Principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, and his team have received a grant for up to $17.25 million from Aligning Research to Impact Autism (ARIA) to become a part of the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network.

11 Jun 2026

Multiple screening methods protect integrity of online health research

While online research is a useful way to reach people who may not take part in in-person studies, researchers are increasingly concerned that fake, automated, and duplicate survey responses can reduce data quality and compromise findings.

11 Jun 2026

Temple Health receives grant to launch family thriving program

Temple Health has been awarded a $700,000 three‑year grant from the William Penn Foundation to develop the Temple Family Thriving Program, a trauma‑informed initiative that integrates caregiver and early childhood support directly into prenatal and postpartum care.

11 Jun 2026

Researchers discover 45 new toxins produced by Salmonella bacteria

Researchers at the University of São Paulo (USP) in Brazil have discovered 45 new toxins produced by Salmonella bacteria, some of which are associated with foodborne infections.

11 Jun 2026

BU professor to examine the role of postpartum hypertension on recurrent HDP risk

Samantha Parker Kelleher, along with researchers at BU School of Public Health and Boston Medical Center, will examine the role of high blood pressure during the postpartum period on the risk of developing recurrent hypertensive disorders of pregnancy, such as preeclampsia and gestational hypertension.

11 Jun 2026