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GLP-1 exposure in pregnancy does not clearly raise major birth defect risk

A systematic review and meta-analysis of seven cohort studies involving more than 40,000 GLP-1 receptor agonist-exposed pregnancies found no statistically significant increase in major congenital malformations or several other adverse pregnancy outcomes. However, the evidence was low or very low certainty, and a urinary malformation signal based on unadjusted data requires cautious interpretation.

10 Jul 2026

Scientists trace severe irritability to the brain’s response to frustration

This review identifies maladaptive responses to frustrative non-reward as a potential mechanism underlying clinically significant irritability, particularly in youth. Animal studies reveal conserved behavioral responses, while human research links frustration to altered neural activity and highlights opportunities for cross-species treatment research.

10 Jul 2026

New study explains why some people are more sensitive to low-frequency noise

Some people are more sensitive to low-frequency noise, such as from ventilation systems, heat pumps, wind turbines and transformers. Why is that?

9 Jul 2026

Transplanted neural progenitor cells survive one year in patients with retinitis pigmentosa

New, previously unpublished clinical data was presented today at ISSCR 2026 demonstrating that transplanted human neural progenitor cells survived for at least one year following subretinal transplantation in patients with retinitis pigmentosa (RP), while maintaining a favorable safety profile.

9 Jul 2026

Stem cell-derived dopaminergic cell transplantation shows encouraging results for Parkinson's disease

The International Society for Stem Cell Research (ISSCR) today announced the presentation of new clinical data from the STEM-PD Phase I/II clinical trial at the ISSCR 2026 Annual Meeting.

9 Jul 2026

Multifloral honey may protect skin cells from UV damage and premature aging

Ongoing research reveals that multifloral honey is a promising candidate for protecting human skin cells from premature ageing and cell damage caused by UV radiation, with the potential for developing future clinical and cosmetic applications.

9 Jul 2026

Off-the-shelf CAR T therapy targets treatment-resistant systemic sclerosis

Today at ISSCR 2026, new preliminary clinical data was presented evaluating an induced pluripotent stem cell (iPSC)-derived CAR T-cell therapy for patients with treatment-resistant systemic sclerosis, a rare autoimmune disease with high mortality.

9 Jul 2026

Wearable forehead patch tracks brain-water shifts during sleep at home

A soft, wireless NIRS forehead patch tracked water-sensitive brain signals during 16 overnight home sleep recordings in four healthy men. The signals changed with EEG/EOG-defined sleep stages, suggesting a new way to study sleep-linked brain-fluid dynamics, although the device did not directly measure CSF flow or glymphatic clearance.

9 Jul 2026

Cohort study investigates the efficacy of traditional Chinese medicine for post-COVID-19 syndrome

Due to the lack of specific Western medicine therapies for post-coronavirus disease 2019 (COVID-19) syndrome in clinical practice, this study aimed to investigate the efficacy of traditional Chinese medicine (TCM) for post-COVID-19 syndrome using a cohort study design and to explore its clinical value in alleviating patients' symptoms and improving clinical outcomes.

9 Jul 2026

New method improves understanding of drug delivery nanoparticles

Modern medicine increasingly relies on targeted drug delivery - a process during which tiny particles (nanoparticles) transport drugs to specific parts of the body.

9 Jul 2026

Physicians often trust incorrect AI treatment recommendations, study finds

In experiments in which physicians made decisions about treating hypothetical patients, the physicians tended to trust incorrect advice presented as being generated by artificial intelligence (AI), even after given the opportunity to notice that patient recovery data contradicted the recommendations.

9 Jul 2026

New microparticles improve biofilm removal from wounds and surgical instruments

Newly developed microparticles can infiltrate stubborn bacterial matrices and release tiny oxygen bubbles to clean surfaces and wounds more efficiently than hydrogen peroxide or other cleaning agents alone, researchers at the University of Illinois Urbana-Champaign report.

9 Jul 2026

Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations

A network meta-analysis of nine randomized controlled trials found that once-weekly semaglutide showed the largest estimated weight-loss effect among GLP-1 receptor agonists tested in adults with mental illness and obesity or related metabolic risk. The authors cautioned that the findings remain preliminary because the evidence base was small, heterogeneous, and largely indirect.

9 Jul 2026

Pediatric mental health treatment surged after the pandemic

When schools closed in the spring of 2020 at the onset of the COVID-19 pandemic, the number of children and adolescents receiving mental health treatment in the United States fell by more than half.

9 Jul 2026

Phelan-McDermid syndrome may be more common than previously believed

New research, led by scientists from the Seaver Autism Center for Research and Treatment at Mount Sinai and published June 28 in Autism Research, has estimated that Phelan-McDermid syndrome (PMS) affects approximately 1 in 7,300 people, making it dramatically more common than previous estimates suggested.

9 Jul 2026