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Open source tool automates data reanalysis to detect rare diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

24 Jun 2026

Review outlines key strategies to overcome antibody drug conjugate resistance

The first Antibody-drug conjugate (ADC) was approved overa quarter-century ago, and today more than 20 have reached the clinic.

24 Jun 2026

Comprehensive gut microbiome analysis reveals robust colorectal cancer signature

Researchers have long suspected that the gut microbiome – the community of bacteria and other microorganisms living in the intestine – is closely linked to colorectal cancer.

24 Jun 2026

Functional brain imaging can help guide accelerated TMS for depression

Mass General Brigham study suggests that functional brain imaging can help guide accelerated transcranial magnetic stimulation for depression.

24 Jun 2026

Duke researchers discover molecules that target vital cell signaling proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

24 Jun 2026

AACR report highlights unequal burden of cancer in the United States

The American Association for Cancer Research (AACR) today released its Cancer Disparities Progress Report 2026, a comprehensive analysis of the unequal burden of cancer in the United States.

24 Jun 2026

Study outlines legal challenges for fetal tissue research in Japan

Human fetal tissue research has contributed to advances in developmental biology, the study of congenital diseases, regenerative medicine, and vaccine development.

24 Jun 2026

Most IVF add-ons lack evidence of fertility benefits

There is a lack of evidence to suggest the majority of in vitro fertilization (IVF) add-ons improve fertility in patients undergoing IVF, according to a systematic review and meta-analysis published in The Lancet Obstetrics, Gynaecology, & Women's Health journal.

24 Jun 2026

Hourly movement breaks effectively counter harms of prolonged sitting

Hourly movement breaks of just 5 minutes each seem to offer the best balance between feasibility and effectiveness for mitigating the health harms of prolonged sitting, suggests a large study carried out under real world conditions and published online in the British Journal of Sports Medicine.

24 Jun 2026

Using blood proteomics to identify pediatric inflammatory bowel disease risk

For children with suspected inflammatory bowel disease (IBD), a chronic, relapsing condition of the gastrointestinal tract, getting the right diagnosis relies on a combination of clinical evaluation, imaging, endoscopy, and histopathology.

24 Jun 2026

Study compares menopause symptom burden across different age groups

There has been a lot of discussion about how the age at menopause can affect menopause symptoms. A new study compared the prevalence and severity of menopause symptoms in women experiencing menopause around the average age of 51 years and those with premature ovarian insufficiency, showing similar symptom burden in the psychological and urogenital domains.

24 Jun 2026

Natural microbial compound helps protect the gut from chronic inflammation

University of Louisville researchers have discovered how a naturally occurring microbial compound may help protect the gut and support future treatment strategies for inflammatory bowel disease (IBD).

24 Jun 2026

New eye imaging technology captures clearer details of retina

Modern OCT devices can look inside the eye without a scalpel - but they do not always capture everything that matters. Some critical information is simply lost, blurred by scattered photons.

24 Jun 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026

LMU researchers discover new genetic cause of Crohn's disease

A team led by LMU physician Daniel Kotlarz has identified a previously unknown genetic cause of Crohn's disease.

24 Jun 2026

Hidden costs push United States dementia toll to historic high

A new USC-led study finds Alzheimer's disease and related dementias will cost the United States an estimated $818 billion this year, driven largely by often-overlooked costs to persons living with dementia and family and friends providing their care.

24 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

Zebrafish model unlocks new insights into hereditary brain disease

CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brain’s small blood vessels, leading to strokes, cognitive decline, and early dementia.

24 Jun 2026

Pioneering technique maps the proteome of individual cardiomyocytes

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes-the cells responsible for heart contraction.

24 Jun 2026

Common genetic difference may increase the risk of severe COVID-19 and lung fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

24 Jun 2026