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High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics.

7 May 2021

COVID-19 may have long-term effects on young, healthy adults

New research published in Experimental Physiology highlight the possible long term health impacts of COVID-19 on young, relatively healthy adults who were not hospitalized and who only had minor symptoms due to the virus.

7 May 2021

Researchers report encouraging results from experimental antiviral targeting Marburg virus

The Marburg virus, a relative of the Ebola virus, causes a serious, often-fatal hemorrhagic fever. Transmitted by the African fruit bat and by direct human-to-human contact, Marburg virus disease currently has no approved vaccine or antivirals to prevent or treat it.

7 May 2021

Increased symptomatic levels of COVID-19 may be associated with psychiatric symptoms

A significant level of symptoms of depression, anxiety and post-traumatic stress may follow COVID-19 independent of any previous psychiatric diagnoses, according to new research by Columbia University Mailman School of Public Health with colleagues at Universidade Municipal de São Caetano do Sul in Brazil.

7 May 2021

Highly efficient immune response in asymptomatic SARS-CoV-2 patients

Researchers in Singapore have investigated the role of SARS-CoV-2-specific antibodies and T-cells in asymptomatic individuals suffering from COVID-19. They found that, contrary to some initial hypotheses, asymptomatic individuals mount an adaptive immune response on par with symptomatic individuals, demonstrating that T cell response does not appear to be correlated with symptom severity.

7 May 2021

Study suggests new avenues for treating Black patients who disproportionately die of prostate cancer

A study designed to enroll an equal number of Black and white men with advanced prostate cancer confirms key findings that have been evident in retrospective analyses and suggest potential new avenues for treating Black patients who disproportionately die of the disease.

7 May 2021

3D-printed fetus models allow surgeons to identify potential obstacles, reduce risks of surgery

A state-of-the-art in-utero procedure allows surgeons to correct a birth defect on developing babies inside the womb. But operating on a mother and her unborn child at the same time can be challenging and unpredictable.

7 May 2021

Researchers discover new binding sites for active agents on cell cytoskeleton

Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute PSI have discovered new binding sites for active agents - against cancer, for example - on a vital protein of the cell cytoskeleton. Eleven of the sites hadn't been known before. The study appears today in the journal Angewandte Chemie International Edition.

7 May 2021

SFHN clinicians support the use of telehealth services for outpatient primary care

As state and federal authorities decide whether to continue reimbursing for telehealth services that were suddenly adopted last spring in response to the coronavirus pandemic, a new study out of UC San Francisco has found that clinicians in the San Francisco Health Network (SFHN) overwhelmingly support using these services for outpatient primary care and specialty care visits.

7 May 2021

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

In the brain of a person with Alzheimer's disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally.

7 May 2021

New mathematical model predicts disease spread patterns

Early on in the COVID-19 pandemic, health officials seized on contact tracing as the most effective way to anticipate the virus's migration from the initial, densely populated hot spots and try to curb its spread.

7 May 2021

New transport system delivers large protein-based drugs into cancer cells

The ability of antibodies to recognize specific cancer cells is used in oncology to specifically target those cells with small active agents.

7 May 2021

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Patients with cancer have a more challenging time with infections while undergoing treatment — placing them as high-risk for severe COVID-19 illness and death. However, how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with cancer therapies remains poorly understood.

7 May 2021

People who feel younger have greater sense of well-being, health benefits

People who feel younger have a greater sense of well-being, better cognitive functioning, less inflammation, lower risk of hospitalization and even live longer than their older-feeling peers.

7 May 2021

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

The global spread of COVID-19 has raised serious concern for patients with chronic disease. A correlation has been identified between the severity of COVID-19 and a patient's preexisting comorbidities.

7 May 2021

Study proposes new protocol for treating cardiac arrhythmias with radio frequency energy and catheterization

An article published in International Journal of Hyperthermia proposes a more effective protocol for the treatment of cardiac arrhythmias when applying radiofrequency energy at the site of the arrhythmia by catheterization.

7 May 2021

Professor Cyrus Cooper receives ECTS Steven Boonen Clinical Research award

The International Osteoporosis Foundation is delighted to announce that the European Calcified Tissue Society (ECTS) has presented the prestigious 2021 ECTS Steven Boonen Clinical Research Award to its President, Professor Cyrus Cooper.

7 May 2021

Bubonic plague had long-term impact on human immune genes, indicates study

Scientists examining the remains of 36 bubonic plague victims from a 16th century mass grave in Germany have found the first evidence that evolutionary adaptive processes, driven by the disease, may have conferred immunity on later generations of people from the region.

7 May 2021

A new method for producing faster and more efficient vaccines

Vaccines are currently a great source of hope for many people, as it is believed they will help to protect society against COVID-19 and pave the way back to a normal life. The current focus is clearly on coronavirus — but vaccines are also fundamental to combating other pathogens.

7 May 2021

Cryptic pocket on the surface of SARS-CoV-2 may be a promising treatment target

In a new study currently available on the bioRxiv* preprint server, a multinational group of researchers modeled an entire membrane-embedded spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and highlighted the potential of a specific mapping approach for unveiling cryptic, potentially druggable pockets on the viral surface.

7 May 2021

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Medical News

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

COVID-19 may have long-term effects on young, healthy adults

Researchers report encouraging results from experimental antiviral targeting Marburg virus

Increased symptomatic levels of COVID-19 may be associated with psychiatric symptoms

Highly efficient immune response in asymptomatic SARS-CoV-2 patients

Study suggests new avenues for treating Black patients who disproportionately die of prostate cancer

3D-printed fetus models allow surgeons to identify potential obstacles, reduce risks of surgery

Researchers discover new binding sites for active agents on cell cytoskeleton

SFHN clinicians support the use of telehealth services for outpatient primary care

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

New mathematical model predicts disease spread patterns

New transport system delivers large protein-based drugs into cancer cells

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

People who feel younger have greater sense of well-being, health benefits

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

Study proposes new protocol for treating cardiac arrhythmias with radio frequency energy and catheterization

Professor Cyrus Cooper receives ECTS Steven Boonen Clinical Research award

Bubonic plague had long-term impact on human immune genes, indicates study

A new method for producing faster and more efficient vaccines

Cryptic pocket on the surface of SARS-CoV-2 may be a promising treatment target

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