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Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

In mice, intestinal infections reshaped dural CD4+ T-cell populations and seeded the brain’s outer meningeal border with antigen-specific memory cells that persisted for months and mounted rapid recall responses to bloodborne antigens. Oral priming was associated with reduced Salmonella spread to the brain and modest cross-protection in an engineered shared-antigen Candida model, although the researchers could not definitively prove that dural CD4+ T cells alone caused the protection.

9 Sep 2026

The link between PM2.5 and ADHD held up after researchers tested other explanations

Using two decades of U.S. county-level data, researchers found that long-term PM2.5 exposure was robustly associated with higher childhood ADHD prevalence, while associations with low birth weight and diabetes weakened after accounting for county-specific temporal trends. The ADHD association persisted after socioeconomic, demographic, state-level, exposure-period, and spatial adjustments, although the ecological study cannot establish an individual-level causal relationship.

9 Sep 2026

The link between fish and pregnancy hypertension may start before conception

In a nationwide Japanese cohort of more than 86,000 women, higher fish intake before pregnancy was associated with lower odds of early-onset hypertensive disorders of pregnancy, while fish intake during pregnancy showed different associations with late-onset disease, particularly among women who had not previously given birth. Total dietary omega-3 and omega-6 PUFA intake showed much less consistent associations, suggesting that the relationship with fish consumption may not be explained by total PUFA intake alone.

9 Sep 2026

Study links methylglyoxal stress to immunotherapy resistance in triple-negative cancer

The metabolism of cancer cells may play a key role in their ability to evade the immune system. This is demonstrated by a new study conducted by researchers at the University of Liège, which reveals how methylglyoxal stress – a by-product of tumor metabolism – promotes immunosuppression and the formation of metastases, and may contribute to resistance to immunotherapy and the progression of triple-negative cancer.

9 Sep 2026

New base editing techniques accurately modify genes in human embryos

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

9 Sep 2026

New genetic map helps track aggressive prostate cancer development

Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with it for years while in others it progresses aggressively.

9 Sep 2026

New genomic language AI model excels in predicting the pathogenicity of genetic variants

More than two decades after scientists first sequenced the entire human genome - all 3 billion "letters," or base pairs, of DNA code - the meaning of much of this code remains a mystery.

9 Sep 2026

Caloric restriction reduces genetic mutations across the mouse genome

Mutations are changes in the molecular "letters" that make up DNA, the genetic blueprint for cells. Mutations build up with age in every cell when DNA is damaged or when cells make mistakes in fixing or copying it.

9 Sep 2026

Laser-carved microvalves prevent hazardous backflow in medical microcatheters

A single cough, deep breath, or shift in posture can turn life-saving medical microcatheters into hazardous two-way streets.

9 Sep 2026

Skin microbiome changes may predict infant eczema and food allergies

The first clues that a baby may develop eczema or food allergies could be hiding in the microscopic organisms living on their skin, according to a study led by researchers in Washington State University's College of Veterinary Medicine.

9 Sep 2026

Standard pediatric blood pressure thresholds miss early trauma warning signs

Blood pressure thresholds commonly used to identify dangerously unstable vital signs in children may not signal trouble soon enough after a traumatic injury, according to a national study of more than 230,000 pediatric trauma patients.

9 Sep 2026

Digital companion apps help secure long-term habits during GLP-1 therapy

Glucagon-like peptide-1 (GLP-1) medications have revolutionized weight management, yet high dropout rates and rapid weight regain remain significant hurdles for many patients.

9 Sep 2026

Ten minutes of slow running boosts brain function and mood

A growing body of evidence shows that exercise improves mood and cognitive function. However, much of this evidence comes from cycling, which allows researchers to precisely control exercise intensity in the laboratory.

9 Sep 2026

New study evaluates medical and surgical treatments for mitral regurgitation

Announcing a new article publication for Cardiovascular Innovations and Applications journal providing fresh evidence on the effectiveness of medical and surgical treatments for mitral regurgitation (MR).

9 Sep 2026

Single-cell atlas reveals key macrophage subtypes in myocardial infarction

Announcing a new article publication for BIO Integration. Myocardial infarction (MI) is characterized by extensive immune activation and dynamic remodeling of the cardiac microenvironment, in which myeloid cells play critical roles in regulating inflammation and tissue repair.

9 Sep 2026

New blood screening algorithm reduces unnecessary Alzheimer's PET scans

A new blood-based screening algorithm dramatically reduced the number of unnecessary PET scans needed to recruit patients at risk of Alzheimer's disease for a clinical trial, according to research from scientists at the Keck School of Medicine of USC published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

9 Sep 2026