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Intensive LDL cholesterol-lowering shows major benefits for heart disease patients

Using cholesterol-lowering medications more intensively to achieve a more aggressive target for low-density lipoprotein cholesterol (LDL-C) reduced the rate of major cardiovascular events by one-third among patients with atherosclerotic cardiovascular disease (ASCVD), according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

Evolocumab reduces cardiac events in high-risk diabetic patients

The cholesterol-lowering therapy evolocumab reduced the risk of major adverse cardiac events by nearly one-third among patients who had no known significant atherosclerosis and had diabetes, according to a study presented at the American College of Cardiology's Annual Scientific Session.

28 Mar 2026

Home-delivered DASH diet improves blood pressure and cholesterol outcomes

Black adults with high blood pressure who received dietitian counseling and home deliveries of groceries aligned with the DASH diet—meaning high in fruits, vegetables, whole grains, low-fat dairy, nuts, seeds, legumes and lean proteins—had an average overall reduction in systolic blood pressure of 7 mm Hg at three months overall and a 5 mm Hg reduction compared with participants who received only basic dietary guidance and a grocery stipend, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

Investigational drug lowers angiotensinogen but shows unclear blood pressure benefits

The investigational drug tonlamarsen—which is designed to lower blood pressure by reducing the production of angiotensinogen, a protein that turns into the hormone that regulates blood pressure—caused a significant and sustained drop in angiotensinogen but its impact on blood pressure was less clear, according to a study presented at the American College of Cardiology's Annual Scientific Session.

28 Mar 2026

Intensive cholesterol‑lowering therapy reduces first major cardiac event in high‑risk patients with diabetes

Mass General Brigham researchers found that the intensive cholesterol‑lowering therapy evolocumab reduced the risk of a first major cardiovascular event in high‑risk patients who did not have known atherosclerosis (the build-up of plaque inside artery walls) but did have diabetes.

28 Mar 2026

Hypercortisolism found in many patients with resistant hypertension

The MOMENTUM study found 27 percent of patients with resistant hypertension have hypercortisolism. This is a significant finding, demonstrating that hypercortisolism is more common in these patients than previously understood by researchers and clinicians.

28 Mar 2026

Microaxial flow pump fails to reduce heart damage in STEMI trial

Using a microaxial flow pump prior to and during cardiac stenting procedures for patients with severe heart attacks who don't have cardiogenic shock does not significantly reduce heart damage.

28 Mar 2026

Catheter-based approach improves prognosis in pulmonary embolism patients

Patients who had low doses of clot-buster drugs delivered directly to the site of a pulmonary embolism (PE) via a catheter using ultrasound to enhance their effect had significantly better outcomes than those who received standard systemic anticoagulants, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

Temporary heart pump before PCI shows no significant benefit

The first randomized trial to test whether adding a small, temporary pump to allow the heart to rest and intentionally delaying percutaneous coronary intervention (PCI), also known as coronary angioplasty, for 30 minutes to reduce heart damage compared with standard immediate PCI in patients with heart attacks at risk for a large amount of heart damage found no significant difference between the two groups, the study's primary endpoint. The research was presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

Left atrial appendage closure matches anticoagulants in AFib patients

For patients with non-valvular atrial fibrillation (AFib) who had no contraindications to taking oral anticoagulants, the use of a device to close off the left atrial appendage in the heart—a small pouch where blood can pool and form dangerous clots—was comparable to standard medication therapy in reducing the combined rate of all-cause stroke, cardiovascular death and systemic embolism at three years.

28 Mar 2026

Heart structure changes in midlife linked to long-term disease risk

Higher left atrial end-systolic dimension (LASD), an increased measurement of the left upper chamber of the heart, and left ventricular mass (LVM), a clinical measurement of the weight of the heart's left ventricular myocardium, are well-established indicators of cardiovascular damage that are associated with a higher risk of cardiovascular disease (CVD) in the short-term (less than 10 years).

28 Mar 2026

Terahertz radiation alters metabolism and signaling in melanoma cells

Terahertz (THz) radiation is increasingly explored for biomedical applications, however, its non-thermal effects on cellular metabolism and regulatory networks remain insufficiently characterized.

28 Mar 2026

AI improves personality testing with faster and more accurate results

Personality tests are widely used in workplaces to shape recruitment, leadership training and team building.

28 Mar 2026

Study reveals immune changes in HIV and HCV coinfected patients

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection leads to severe systemic inflammation, increasing non-AIDS morbidity and mortality risk. CD39 ectoenzyme on T-cells, which catalyzes the conversion of pro-inflammatory purines to immunosuppressive adenosine, plays an important role in inflammation control.

28 Mar 2026

Children redefine what makes play meaningful and enjoyable

Play is critical for kids’ development — but ‘play’ in research is often defined by adult scientists, not the children themselves.

28 Mar 2026

Brain resilience peaks about an hour after stress exposure

Psychological resilience is often misunderstood as simple "toughness" or an insensitivity to stress. However, true resilience is the brain's capacity to adapt and recover after a stressful event.

28 Mar 2026

Experts gather to address evolving food safety risks in Europe

Leading scientists, policymakers, industry representatives and early-career researchers from across Europe will gather on 10-11 June 2026 at Wageningen University & Research (Netherlands) for the joint final conference of the EU-funded HOLiFOOD and FoodSafeR projects.

28 Mar 2026

Perceived partner effort boosts cognitive control during cooperative tasks

A study assesses whether perceiving a partner's effort leads to greater engagement of executive control mechanisms to maintain focus on a task.

28 Mar 2026

Ultrasound advances offer noninvasive assessment of portal hypertension severity

Portal hypertension (PH), a serious complication of liver cirrhosis, is defined as a pressure gradient > 5 mmHg between the portal vein and the inferior vena cava.

27 Mar 2026

New research links cooking methods to better nutrient absorption

Researchers at the University of Seville's Food Colour and Quality Laboratory have studied the effects of different cooking methods used for tomatoes and carrots (in the oven, microwave or air fryer, amongst others) on the amount of carotenoids that are potentially available for absorption by the body following the digestion of these foods.

27 Mar 2026