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What happens in the brain on psychedelics? Scientists identify a common circuit pattern

Researchers combined 11 international resting-state fMRI datasets to map how psychedelic drugs reshape brain connectivity across cortical and subcortical circuits. The mega-analysis found a shared signature of stronger coupling between transmodal association networks and unimodal or sensorimotor systems, alongside selective and variable reductions in within-network connectivity.

7 Apr 2026

New blood test spots four cancers and other diseases by stripping away healthy DNA noise

MethylScan is a new low-cost cell-free DNA methylome test that removes much of the healthy blood DNA background, helping rare disease signals stand out more clearly. In more than 1,000 people, it showed strong performance for detecting four cancers, classifying liver diseases, and identifying organ-specific damage.

7 Apr 2026

AI tool predicts Barrett’s esophagus recurrence with high accuracy

A new artificial intelligence (AI)–based tool shows promise for improving surveillance in patients treated with endoscopic eradication therapies for Barrett's esophagus (BE) related dysplasia and early esophageal adenocarcinoma.

7 Apr 2026

Gladstone investigator wins MIND Prize to decode hidden Alzheimer’s genetics

Gladstone Institutes investigator Ryan Corces, PhD, has been named a 2026 winner of the Pershing Square Foundation's MIND Prize, a prestigious award recognizing next-frontier thinkers who are uncovering a deeper understanding of the brain and cognition.

7 Apr 2026

Geographic disparities persist in the decline of U.S. cancer deaths

In 1991, the U.S. experienced a significant shift in cancer death rates, as, for the first time, deaths began a steady decline that continues to the present day. Researchers at Mississippi State's Social Science Research Center, in partnership with scientists at Oak Ridge National Laboratory, examined this decline to identify where and who benefited the most from this dramatic improvement.

7 Apr 2026

Pol theta enzyme identified as key driver of cancer resilience

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

7 Apr 2026

Newly developed smart molecules offer a safer and more precise approach to cancer care

Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care.

7 Apr 2026

Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers

A new research paper was published in Volume 18 of Aging-US on March 26, 2026, titled "Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodeling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF)."

7 Apr 2026

Mount Sinai launches Adams Valve Institute for advanced heart care

The Mount Sinai Health System today announced the launch of the Adams Valve Institute, a new global center dedicated to advancing comprehensive care and surgical techniques for patients with heart valve disease.

7 Apr 2026

OYE Therapeutics doses first subject in bridging study of intravenous caffeine formulation

OYE Therapeutics Inc., a clinical-stage biotechnology company developing therapies for perioperative and emergency medicine, announced that the first subject has been dosed in its scientific bridging study evaluating OYE-101.

7 Apr 2026

TIFR researchers identify protein essential for survival and function of vomeronasal sensory neurons

Researchers at the Tata Institute of Fundamental Research (TIFR), Hyderabad, have identified a mammalian protein, Cnpy1 (Canopy1), that is essential for the survival and function of vomeronasal sensory neurons in mice.

7 Apr 2026

Navigated TMS significantly boosts combat PTSD recovery rates

An advanced version of a procedure using magnetic fields to stimulate brain nerve cells in treating depression was significantly effective for 85% of active military and veterans suffering from combat post-traumatic stress disorder enrolled in a recent study, when added to psychotherapy.

7 Apr 2026

Study reveals racial and ethnic disparities in pediatric e-scooter injuries

As electric scooters (e-scooters) become more available in cities and urban areas, injuries are becoming more common - especially among teenage boys.

7 Apr 2026

Lactate modification fuels drug resistance and immune escape in cancer

Published in Current Molecular Pharmacology, a comprehensive review led by Yong Xu and colleagues from Shanghai Pulmonary Hospital explores the emerging role of lactylation, a post-translational modification driven by lactate, in lung cancer progression and drug resistance.

7 Apr 2026

Review identifies TREM-1 as key amplifier of inflammatory diseases

Published in Current Molecular Pharmacology, a comprehensive review by Eman R. Al Sawy and colleagues from Cairo University consolidates evidence on the triggering receptor expressed on myeloid cells-1 (TREM-1) as a central amplifier of inflammatory responses.

7 Apr 2026

High-resolution model identifies nationwide plague risk zones in Madagascar

Announcing a new article publication for Zoonoses journal. Plague (Yersinia pestis) remains endemic in Madagascar and causes recurrent outbreaks leading to substantial mortality.

7 Apr 2026

First participants join clinical study to fast-track dementia research in the UK

The Dementia Trials Accelerator has taken a significant step towards transforming dementia clinical trials in the UK by welcoming its first participants into clinics for simple tests that will ultimately get the right people into clinical trials quicker, speeding up vital research.

7 Apr 2026

Base editing corrects genetic mutation responsible for severe form of inherited epilepsy

University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the underlying cause of a severe form of epilepsy in lab mice.

7 Apr 2026

WSU researchers use spice extracts to enhance medical bone implants

An extract of turmeric and ginger helps bone implants bond strongly while killing bacteria and cancer cells, according to new research from Washington State University with implications for millions of patients with joint replacements and bone cancer.

7 Apr 2026

Interpretable machine learning model advances analysis of complex genetic traits

A new study published in Genome Research presents an interpretable artificial intelligence framework that improves both the accuracy and transparency of genomic prediction, a key challenge in fields such as precision medicine, crop science, and animal breeding.

7 Apr 2026

Medical News

What happens in the brain on psychedelics? Scientists identify a common circuit pattern

New blood test spots four cancers and other diseases by stripping away healthy DNA noise

AI tool predicts Barrett’s esophagus recurrence with high accuracy

Gladstone investigator wins MIND Prize to decode hidden Alzheimer’s genetics

Geographic disparities persist in the decline of U.S. cancer deaths

Pol theta enzyme identified as key driver of cancer resilience

Newly developed smart molecules offer a safer and more precise approach to cancer care

Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers

Mount Sinai launches Adams Valve Institute for advanced heart care

OYE Therapeutics doses first subject in bridging study of intravenous caffeine formulation

TIFR researchers identify protein essential for survival and function of vomeronasal sensory neurons

Navigated TMS significantly boosts combat PTSD recovery rates

Study reveals racial and ethnic disparities in pediatric e-scooter injuries

Lactate modification fuels drug resistance and immune escape in cancer

Review identifies TREM-1 as key amplifier of inflammatory diseases

High-resolution model identifies nationwide plague risk zones in Madagascar

First participants join clinical study to fast-track dementia research in the UK

Base editing corrects genetic mutation responsible for severe form of inherited epilepsy

WSU researchers use spice extracts to enhance medical bone implants

Interpretable machine learning model advances analysis of complex genetic traits

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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