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HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

HonorHealth Research Institute recently treated the first patient in a 50-site international clinical trial that will test a new type of therapy aimed at difficult-to-treat melanoma, an aggressive type of skin cancer.

29 Apr 2025

Northwestern researchers call for better survivorship care for cancer patients

More Americans are beating cancer than ever, yet many still grapple with treatment's long shadow - especially on their mental health.

29 Apr 2025

Machine learning uncovers promising drug leads against human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

29 Apr 2025

Why different loneliness tests still identify the same emotional struggles

Researchers examined how loneliness classifications, by frequency, distress, or chronicity, relate to cognitive and behavioral traits in 790 adults. Despite modest agreement between classification methods, the study found consistent psychological patterns among lonely individuals across all types of loneliness.

29 Apr 2025

Measles makes a deadly comeback in Europe as vaccine gaps widen

In 2024, measles cases in Europe soared to the highest levels in decades, with over 35,000 reported cases, 87% from Romania alone. Most affected were unvaccinated children, revealing critical immunity gaps and suboptimal vaccination coverage across the EU/EEA.

29 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy based on the detection of the same genomic alteration in both tissue and liquid biopsies compared with both standard-of-care treatment and tailored therapy that was based on either biopsy on its own, according to results from the phase II, multicenter ROME trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Cancer-related fatigue and depression found to limit recreational activities in survivors

Cancer survivors who reported feeling cancer-related fatigue or depression reduced their recreational activities nearly twofold, with females more likely than males to report feeling either cancer-related fatigue or depression, according to a retrospective study presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance of intratumoral microbiota-microbiota inside tumors-in CRC progression.

29 Apr 2025

Genetic predisposition to muscle strength linked to lower cardiovascular mortality

A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, found that men with a genetic predisposition supporting higher muscle strength had a lower risk of dying from cardiovascular diseases, regardless of their leisure-time physical activity levels or other lifestyle-related factors.

29 Apr 2025

New compounds identified as inhibitors of DNA topoisomerase 1

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA.

29 Apr 2025

New CAR T cell therapy shows promise for treating advanced thyroid cancer

A new chimeric antigen receptor (CAR) T cell therapy called AIC100, which targets the ICAM-1 protein, demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

29 Apr 2025

Noninvasive decoder could help restore movement after spinal cord injury

When a person sustains an injury to the spinal cord, the normal communication between the brain and the spinal circuits below the injury are interrupted, resulting in paralysis.

29 Apr 2025

Intimate relationships may shield against cognitive decline during chemo

A satisfying intimate relationship may help diminish chemotherapy-related cognitive problems experienced by patients with breast cancer, a new study suggests.

29 Apr 2025

Teen depression may offer better treatment opportunities with flexible symptoms

Depression in young teens could be easier to treat than in adulthood due to the symptoms being more flexible and not yet ingrained, a study shows.

29 Apr 2025

$Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma$

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukaemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.

29 Apr 2025

Medical News

HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

Northwestern researchers call for better survivorship care for cancer patients

Machine learning uncovers promising drug leads against human enterovirus 71

Why different loneliness tests still identify the same emotional struggles

Measles makes a deadly comeback in Europe as vaccine gaps widen

Gut bacteria and metabolites reveal depression-linked patterns in older adults

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Cancer-related fatigue and depression found to limit recreational activities in survivors

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Genetic predisposition to muscle strength linked to lower cardiovascular mortality

New compounds identified as inhibitors of DNA topoisomerase 1

New CAR T cell therapy shows promise for treating advanced thyroid cancer

Noninvasive decoder could help restore movement after spinal cord injury

Intimate relationships may shield against cognitive decline during chemo

Teen depression may offer better treatment opportunities with flexible symptoms

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Researchers uncover how substance use accelerates brain aging

Synthetic tau protein reveals key insights into protein misfolding and fibril formation

Researchers discover new biomarker to predict multiple sclerosis progression

A journey through science, software, and innovation: Insights from the Bruker software team

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