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Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis.

4 Dec 2025

Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.

4 Dec 2025

Engineered herpes virus activates potent immune responses against glioblastoma

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells.

4 Dec 2025

Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive procedures like cystoscopies.

4 Dec 2025

Early pregnancy placenta models show significant effects from PFAS exposure

Per- and polyfluoroalkyl substances (PFAS) are a group of nearly 10,000 long-lasting chemical compounds that stay in the environment and have been linked to adverse health effects on humans, including pregnant women and their unborn children.

4 Dec 2025

Concussion history accurately predicts long-term health in former NFL players

A UNC-Chapel Hill study conducted by the Matthew Gfellar Center studied more than 1,500 former NFL players found that two of the most commonly used ways to estimate head injury risk, years played and playing position, are not actually linked to poorer long-term physical or mental health.

4 Dec 2025

Breakthrough in imaging speed moves portable stroke diagnosis closer to reality

When someone walks into an emergency room with symptoms of a stroke, every second matters. But today, diagnosing the type of stroke, the life-or-death distinction between a clot and a bleed, requires large, stationary machines like CT scanners that may not be available everywhere.

4 Dec 2025

Long-acting HIV treatment could improve outcomes for breastfeeding women

Sujata Tewari, BA, previously of the Medical Practice Evaluation Center (MPEC) at Massachusetts General Hospital, and Andrea L. Ciaranello, MD, MPH, of the MPEC and Department of Medicine at Massachusetts General Hospital, are the lead and senior authors of a paper published in the Journal of Infectious Diseases, “Long-acting antiretroviral therapy for breastfeeding women with HIV experiencing barriers to adherence in Zimbabwe: Modeling clinical impact and cost-effectiveness.

4 Dec 2025

Psychosocial stress in women linked to early signs of heart tissue changes

Women who report high levels of psychosocial stress, such as from caregiving and lack of emotional support, show signs of early heart tissue changes associated with cardiovascular disease – an association not observed in men, a new study reveals.

4 Dec 2025

Chronic kidney disease accelerates cognitive decline through heart-brain pathways

A new study published in the American Journal of Physiology - Heart and Circulatory Physiology reveals that chronic kidney disease (CKD) accelerates cognitive decline through interconnected damage to the heart and brain-and that these pathways differ markedly between men and women.

4 Dec 2025

Rising nighttime heat is linked to shorter and more disrupted sleep

Higher nighttime temperatures are linked to shorter sleep times and lower sleep quality, especially for people with chronic health conditions, lower socioeconomic status, or those living on the West Coast, according to a new USC study.

4 Dec 2025

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years.

4 Dec 2025

Planned birth at term shown to cut pre-eclampsia risk in high-risk women

Planned birth at term reduces the incidence of pre-eclampsia in women at high risk of the condition, without increasing emergency Caesarean or neonatal unit admission, according to new trial results.

4 Dec 2025

Scientists reveal how the brain reshapes episodic memories over time

A study from the University of East Anglia is helping scientists better understand how our brains remember past events - and how those memories can change over time.

4 Dec 2025

New audio-enhancing device can improve mindfulness in a distracting world

The whisper of two palms rubbing together. The squeak of a marker on a whiteboard. The swish of fabric against fabric. The woosh of a running faucet. These sounds can help center the mind on the present moment.

4 Dec 2025

Scientists uncover why SETX-deficient cancer cells rely on error-prone DNA repair

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

4 Dec 2025

Emotional support in marriage associated with lower BMI and fewer food cravings

Strong social relationships, particularly high-quality marriages, may help protect against obesity by influencing a complex communication system between the brain and gut, according to new research by UCLA Health.

4 Dec 2025

Survey reveals widespread misconceptions about the role of certified nurse-midwives

According to the Department of Health and Human Services, the United States is expected to face a significant shortage of OB-GYNs in the next five years.

4 Dec 2025

Researchers capture high-resolution footage of flu viruses entering human cells

For the first time, researchers have observed live and in high resolution how influenza viruses infect living cells. This was possible thanks to a new microscopy technique, which could now help to develop antiviral therapies in a more targeted manner.

4 Dec 2025

Long-term air pollution exposure linked to more advanced coronary artery disease

Long-term exposure to common air pollutants is associated with more advanced coronary artery disease-with notable differences between women and men-according to a large-scale study of more than 11,000 adults being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2025