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Indiana University physician joins FDA panel on male hormone therapy

Helen Bernie, DO, MPH, assistant professor of urology at Indiana University School of Medicine, will participate in an expert panel on testosterone replacement therapy and men's health to be held Wednesday, Dec. 10, by the U.S. Food and Drug Administration. Bernie's role on the panel is that of a clinical expert on men's reproductive health, which is the focus of both her practice and academic research.

12 Dec 2025

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

While patients with acute myeloid leukemia (AML) are routinely treated with chemotherapy and other cell-killing therapies, existing options do not lead to favorable clinical outcomes in all patients.

12 Dec 2025

Rural health providers hit by $100K Trump visa fee

More than 30 people have applied for a lab technician job at West River Health Services in Hettinger, North Dakota, a thousand-person town in the rural southwestern part of the state.

12 Dec 2025

Human heart organoids enable new therapies for atrial fibrillation

Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular and often fast heartbeat, it's been at least 30 years since any new treatments have been developed.

12 Dec 2025

Interdisciplinary project aims reduce noise exposure for premature children in neonatal care

Premature babies are particularly susceptible to strong sensory impressions and high sound levels from the incubator. Now researchers will look at what can be done to protect children's hearing and development.

12 Dec 2025

Pediatric critical care survivors often lack prompt primary care follow up

When the unthinkable happens and a child is left critically ill or injured, the miracle workers in pediatric intensive care units around the country work tirelessly to save their lives.

12 Dec 2025

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors and clinical course, and underscoring the importance of early diagnosis and treatment.

12 Dec 2025

Early relapse predicts poor survival in mature nodal T-cell lymphoma

Mature nodal T-cell lymphoma is a type of rare and aggressive blood cancer. Limited data make it difficult to identify high-risk patients or tailor treatment strategies, so most patients receive similar care despite differences in disease characteristics and outcomes.

12 Dec 2025

Varenicline helps young people quit nicotine vaping regardless of cannabis use

Adolescent and young adult nicotine vaping has become an urgent public health concern, as 2024 marked the first year that nicotine vaping was the most initiated drug.

12 Dec 2025

Exploring melatonin therapeutic potential in systemic lupus erythematosus

A recent review published in Current Molecular Pharmacology explores the therapeutic potential of melatonin in systemic lupus erythematosus (SLE), a complex autoimmune disease affecting multiple organs.

12 Dec 2025

Glycation stress drives aortic stiffening through oxidative stress and senescence

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled "Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence."

12 Dec 2025

Novel nanomedicine mPEG@ELA-11 shows potential in treating atherosclerosis

A pioneering study led by researchers from Tongji University School of Medicine, Shanghai Jiao Tong University School of Medicine and Naval Medical University has unveiled a novel nanomedicine, mPEG@ELA-11, which demonstrates significant potential in treating atherosclerosis (AS), a leading cause of cardiovascular diseases globally.

12 Dec 2025

Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

Heart attacks that occur at night are less severe than those that strike during the day. A new study from the Centro Nacional de Investigaciones Cardiovasculares (CNIC) explains why. Published in the Journal of Experimental Medicine, the study led by Dr. Andrés Hidalgo's group at the CNIC shows that neutrophils-a type of white blood cell-have an internal clock that regulates their aggressiveness throughout the day and determines the extent of damage they cause to the heart after a heart attack.

12 Dec 2025

Tianjin grading system improves prognosis prediction in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools.

12 Dec 2025

Autoimmune attack on CASPR2 drives nerve hyperexcitability and involuntary muscle activity

A scientific review on autoimmune neurological diseases reveals what occurs in our body when the immune system, by mistake, produces antibodies that target a protein essential for the normal functioning of nerves.

12 Dec 2025

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones.

12 Dec 2025

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

The interaction between genetics and tissue environment shapes how individual teeth form in different regions of the jaw.

12 Dec 2025

AI-guided discovery of selective DGKα inhibitors to overcome checkpoint resistance in solid cancers

Insilico Medicine has developed a new class of small molecule inhibitors targeting diacylglycerol kinase alpha (DGKα) designed to restore T cell function and overcome resistance to immune checkpoint blockades in solid cancers.

12 Dec 2025

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery.

12 Dec 2025

Medical News

Indiana University physician joins FDA panel on male hormone therapy

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

Rural health providers hit by $100K Trump visa fee

Human heart organoids enable new therapies for atrial fibrillation

Interdisciplinary project aims reduce noise exposure for premature children in neonatal care

Pediatric critical care survivors often lack prompt primary care follow up

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Early relapse predicts poor survival in mature nodal T-cell lymphoma

Varenicline helps young people quit nicotine vaping regardless of cannabis use

Exploring melatonin therapeutic potential in systemic lupus erythematosus

Glycation stress drives aortic stiffening through oxidative stress and senescence

Novel nanomedicine mPEG@ELA-11 shows potential in treating atherosclerosis

Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

Tianjin grading system improves prognosis prediction in pancreatic cancer

Autoimmune attack on CASPR2 drives nerve hyperexcitability and involuntary muscle activity

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

AI-guided discovery of selective DGKα inhibitors to overcome checkpoint resistance in solid cancers

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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