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New method reveals how the genome is regulated and disrupted in diseases

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer.

8 Apr 2026

Apparent drug overdose spike in 2025 driven by flawed modeling

Last June, several mainstream media outlets reported a surge in U.S. drug overdose deaths in early 2025 that was based on data from the U.S. Centers for Disease Control and Prevention (CDC).

8 Apr 2026

Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

8 Apr 2026

Self-employment linked to lower heart disease risks in Hispanic women

Self-employed Hispanic women report less high blood pressure, obesity, diabetes, poor health and binge drinking compared to Hispanic women working for salary or wages, new research suggests.

8 Apr 2026

Global Flourishing Study releases largest dataset on human well-being

The Global Flourishing Study (GFS), the most comprehensive empirical investigation of human flourishing ever undertaken, today made its first two waves of data publicly available through the Center for Open Science at no cost and without pre-registration. Researchers, journalists, policymakers and the public can now freely access the dataset on the Open Science Framework (OSF) website.

8 Apr 2026

Preconditioned skin cells enable faster and more effective wound healing

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

8 Apr 2026

Psychology students gain interaction skills by watching therapists work

Psychology students who will work with patients during supervised professional training can benefit from observing experienced therapists at work.

8 Apr 2026

Flu vaccines protect children well across Europe, but H3N2 remains harder to stop

Influenza vaccination provided strong real-world protection for children in European primary care across two seasons, with overall vaccine effectiveness of 68% in 2022–2023 and 71% in 2023–2024. Protection was highest against influenza B and H1N1, while H3N2 showed lower and more variable effectiveness, supporting the need for higher uptake and continued monitoring.

8 Apr 2026

Sponge and sea slug partnership yields a new anticancer molecule with drug design promise

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

8 Apr 2026

Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours

Researchers found that cola exposure quickly lowered pH and altered the microbiome on the inner surface of clear aligners, with the greatest disruption observed when aligners were removed before drinking and then reinserted. In this small 24-hour study, wearing aligners during exposure appeared less disruptive than removing them, though the authors said the mechanism still needs further study.

8 Apr 2026

Why early-onset cancers are rising and how researchers plan to stop them

Early-onset cancers are rising worldwide, and this Cell Perspective argues that cancer prevention must move beyond static risk-factor snapshots toward life-course exposure mapping, tissue-level biology, and dynamic estimates of preventability. The authors propose three linked frameworks to speed discovery of cancer causes and translate those findings into more precise prevention and interception strategies.

8 Apr 2026

Breastfeeding patterns in India differ between slum and non-slum neighborhoods

A new study from the University of Toronto shows that where a mother lives in an Indian city – in a slum or a non‑slum neighborhood – is linked to how she breastfeeds her baby.

8 Apr 2026

Genetic overlap links psychiatric disorders with many physical ailments

For centuries, mental illness and physical disease have been viewed as two distinct categories, each with its own field of study, its own doctors, and its own menu of treatments.

8 Apr 2026

New steerable optical fiber reaches previously inaccessible larynx tumors

Worcester Polytechnic Institute (WPI) researchers have developed a flexible optical fiber that can be threaded through a medical endoscope and steered into the larynx to destroy hard-to-reach tumors on the vocal folds, an advance that could expand outpatient laser treatment options for patients whose only other choice might be surgery under general anesthesia.

8 Apr 2026

Long-term excess weight is a stronger predictor of cardiovascular risk

Obesity is a known risk factor for cardiovascular disease, but people's weights can shift over time, and little is known about the cumulative impact of excess weight.

8 Apr 2026

Social support, physical health and spiritual engagement help older adults truly flourish

Older Canadians who are socially connected, physically healthy, and spiritually engaged are significantly more likely to experience complete mental health, according to a new nationally representative study examining adults aged 65 and older.

8 Apr 2026

Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually and in trials, which are still at a very preliminary stage, in a review study published in the journal Trends in Pharmacological Sciences.

8 Apr 2026

Insilico Medicine nominates AI-driven drug candidate for cancer, Cushing's syndrome and obesity

The NR3C1 (nuclear receptor subfamily 3 group C member 1) gene encodes the glucocorticoid receptor (GR), a nuclear receptor vital for maintaining physiological homeostasis, and inhibition of NR3C1 could increase the sensitivity of cancer cells to standard chemotherapy, particularly in ovarian cancer.

8 Apr 2026

New monoclonal antibody shows promise for preventing Lyme disease

A Phase I clinical trial of a human monoclonal antibody discovered and developed at UMass Chan Medical School for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data presented by Mark Klempner, MD, at the World Vaccine Congress 2026 in Washington D.C.

8 Apr 2026

Study reveals how tau tangles spread from one brain region to another in Alzheimer's

Alzheimer's disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with daily functioning.

8 Apr 2026