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One-time gene editing cuts LDL cholesterol in early hypercholesterolemia trial

A phase 1 NEJM interim analysis found that a single infusion of the investigational base-editing therapy VERVE-102 produced dose-dependent reductions in circulating PCSK9 protein and LDL cholesterol in adults with heterozygous familial hypercholesterolemia or premature coronary artery disease.

26 May 2026

ICU pneumonia mortality rates remain elevated in developing nations

A scientific review published today in the NEJM Evidence journal, coordinated by the D'Or Institute for Research and Education (IDOR), evaluated outcomes of adults with community-acquired pneumonia (CAP) admitted to intensive care units (ICUs) in middle-income countries.

26 May 2026

Retatrutide reshapes metabolism in obesity and type 2 diabetes, study finds

Retatrutide altered circulating metabolites and lipids linked to fatty acid oxidation and insulin resistance in people with obesity, with or without type 2 diabetes. These biomarker changes suggest improved metabolic health, but the post-hoc analysis remains hypothesis-generating and does not prove direct clinical benefit.

26 May 2026

Macrophage location within tumors may influence cancer progression outcomes

Cancer tumors are surrounded by immune cells, but not all of those cells help the body fight back. Some support anti-cancer immunity, while others can unexpectedly help tumors survive.

26 May 2026

Colorful Nutri-Score labels attract more consumer attention in supermarkets

Anyone seeking to purchase healthy products at the supermarket needs clear guidance. Nutritional labelling schemes, such as Nutri-Score labels, are designed to help with that.

26 May 2026

Study links fathers’ preconception stress to altered offspring development

Research from the University of Colorado Anschutz suggests that stress experienced by a father before conception may influence an offspring's growth by altering small molecular signals in sperm.

26 May 2026

Urine test may help identify autism risk in children

A simple urine test may help identify children at risk for autism sooner than current assessments - opening the door for earlier diagnosis and treatment, and better long-term outcomes for children who do have autism spectrum disorder.

26 May 2026

Early multidisciplinary care speeds concussion recovery in children

Children recover significantly faster from concussion after receiving early, multidisciplinary care designed to treat persistent symptoms, according to a new study.

26 May 2026

Rare dual transplant gives Michigan patient a second chance

After nearly two decades of life-threatening illness, repeated complications, and organ failure, 33-year-old Briana Dery of Twining, Mich., is looking ahead to a healthy future, after successfully undergoing one of the rarest and most complex procedures in modern medicine.

26 May 2026

Nerve freezing technique reduces pain after surgical repair for microtia

Ann & Robert H. Lurie Children's Hospital of Chicago is the first in the world to eliminate months of pain after surgical repair for microtia – a rare condition where a child is born with underdeveloped or missing outer ear.

26 May 2026

Researchers uncover possible cause of pain in neurofibromatosis type 1

Researchers at Cincinnati Children's have identified a potential new way to relieve chronic pain linked to neurofibromatosis type 1 (NF1), a genetic condition best known for causing tumors to grow along nerves.

26 May 2026

In-person prayer reduced pain and anxiety more than music

This randomized controlled trial focused on in-person prayer, known as proximal intercessory prayer (PIP), for another person's well-being.

26 May 2026

Adults with developmental disabilities or cerebral palsy face earlier fall injury risks

Falls are a common cause of injury, especially for adults over age 65. But adults with intellectual and/or developmental disabilities or cerebral palsy may also be at higher risk.

26 May 2026

Minority patients report confusion about Medicare Annual Wellness Visits

Medicare Annual Wellness Visits (AWVs) are free, yearly preventive checkups available to all Medicare and Medicare Advantage enrollees.

26 May 2026

FIT intervention boosts colorectal cancer screening across racial/ethnic groups

Background: Racially and ethnically minoritized patients are underscreened for colorectal cancer, resulting in racial/ethnic disparities.

26 May 2026

Guava juice boosts hemoglobin levels in women with anemia

Regular guava juice consumption may prove a readily accessible and affordable addition to helping lower the risk of anemia in women in low and middle income countries, suggests a synthesis of the available evidence, published in the open access journal BMJ Nutrition Prevention & Health.

26 May 2026

New study tests vitamin D analog against pancreatic cancer

A small clinical trial led by Dana-Farber Cancer Institute researchers put a Salk Institute idea to the test in patients: that activating the vitamin D receptor can help reshape the protective environment surrounding pancreatic tumors in ways that could make the notoriously difficult-to-treat cancer more vulnerable to therapeutic treatments.

26 May 2026

Special yoga intervention helps cancer survivors manage psychological side effects

University of Rochester Medicine is in the spotlight at a national meeting for a new discovery in integrative oncology: A special yoga intervention, the study shows, goes a step further than other side-effect therapies to improve four domains of physical and psychological side effects that most patients experience, including lifting mood and easing anxiety.

26 May 2026

Scientists target root of relapse in aggressive childhood brain tumors

Stopping cancer from coming back is the goal of new research from MUSC Hollings Cancer Center, where scientists are targeting cells that fuel the return of an aggressive pediatric brain tumor.

26 May 2026

New AI tools identify potential drugs for rare Ebola virus

Recent advances in artificial intelligence have enabled Southwest Research Institute (SwRI) to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.

26 May 2026