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Protein-sharing helps dormant bacteria withstand antibiotic treatment

When bacteria are under antibiotic attack, it is not 'every man for himself.' Researchers at Baylor College of Medicine and colleagues from collaborating institutions have discovered that bacterial populations work as a team to survive antibiotics.

25 Jun 2026

New calculator predicts statin-related muscle disorder risk

Researchers at the Nuffield Department of Primary Care Health Sciences, University of Oxford, have developed a new calculator that estimates a person's risk of developing serious muscle disorders from statins.

25 Jun 2026

Cone opsin structures offer insights into vision loss

The retina of the human eye contains six to seven million cone cells. These cells contain light-sensitive proteins known as cone opsins.

25 Jun 2026

Common drug shows promise in preventing post-surgical liver failure

A multi-center study, co-led by researchers at Mayo Clinic and Michigan State University, found that patients who received tranexamic acid during liver surgery were three times less likely to develop post-hepatectomy liver failure than patients who received a placebo.

25 Jun 2026

Experts urge neglected tropical disease status for ocular toxoplasmosis

One third of the world's population is infected with the Toxoplasma parasite, which can cause ocular toxoplasmosis, an eye infection that can damage the retina and result in permanent vision loss.

25 Jun 2026

Blood metabolites reveal lifestyle links to brain health before dementia

Blood metabolome profiling in dementia-free middle-aged adults linked 14 metabolites to cognition and 22 metabolites to MRI markers of brain health. Lifestyle, clinical factors, medication use and gut microbiota appeared to shape many of these metabolites, with ergothioneine emerging as a notable cognition-linked signal.

25 Jun 2026

Natural compound puerarin may protect against cholestatic liver fibrosis

A recent study published in Current Molecular Pharmacology demonstrates that puerarin-a bioactive isoflavone derived from Kudzu root and widely used in traditional Chinese medicine-may offer significant therapeutic benefits against cholestatic liver fibrosis, a progressive pathological condition arising from impaired bile formation and flow that currently lacks effective pharmacotherapies.

25 Jun 2026

Iron overload gradually increases neurons' vulnerability to neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease Association and Parkinson's Foundation report roughly 7 million people with Alzheimer's and another million with Parkinson's.

25 Jun 2026

Dogs could transform the future of autism drug development

For thirty years the search for autism medicines has hit the same wall, and a new peer-reviewed Perspective in Genomic Psychiatry suggests that the way around it has been sleeping at our feet the entire time.

25 Jun 2026

Opposing protein pathways control skin regeneration and disease development

Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found.

25 Jun 2026

Good oral health could improve athletic performance

Millions of fans around the world will be glued to screens in the coming weeks to watch remarkable displays of speed, precision and endurance in the world's most important football competition.

25 Jun 2026

Lactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinoma

A comprehensive review recently published in Current Molecular Pharmacology illuminates the pivotal, multifaceted roles of lactate and its downstream protein modification, lactylation, in pancreatic ductal adenocarcinoma (PDAC).

25 Jun 2026

Exercise, not liraglutide alone, drives vascular gains after obesity-related weight loss

A prespecified secondary analysis of the S-LiTE trial found that regular exercise reduced carotid artery wall thickness and circulating levels of inflammatory cytokines in adults with obesity who had already achieved substantial diet-induced weight loss. Liraglutide alone did not significantly improve these vascular or inflammatory markers, while exercise plus liraglutide also improved endothelial function biomarkers.

25 Jun 2026

Scientists find a universal gut microbiome pattern linked to colorectal cancer

Researchers analyzed 6,779 stool microbiome profiles and 906 tissue samples to identify a colorectal cancer microbial signature that remained consistent across age groups, populations, and sequencing methods. The signature aligned with tumor-resident microbes, showed weaker detection for adenomas, and was inversely associated with dietary fiber intake.

25 Jun 2026

Researchers develop novel strategy to selectively target tumor microenvironments

A new collaborative study reports the discovery and application of a novel therapeutic strategy to selectively target EGFR and other kinases with controlled release in tumor microenvironments to improve therapeutic efficacy, with promising results.

25 Jun 2026

New cell culture method allows targeted study of antibody regulation

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance.

25 Jun 2026

Musculoskeletal pain in children is often underestimated and misunderstood

Three out of every ten Brazilian children and adolescents complain of musculoskeletal pain (affecting bones, ligaments, and muscles).

25 Jun 2026

Study uncovers mechanism driving metastasis in aggressive gastric cancer

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA PVT1 and the translation initiation factor EIF4A1 cooperate to drive gastric cancer metastasis.

25 Jun 2026

Base editing technique reveals crucial gene for early human development

Research led by the University of Cambridge Loke Centre for Trophoblast Research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.

25 Jun 2026

Peacemaker immune cells offer new hope for restoring immune tolerance

'Peacemaker' immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.

25 Jun 2026