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Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset of patients benefit. Many solid tumors remain "cold," characterized by poor immune cell infiltration and resistance to immune checkpoint blockade (ICB).

15 May 2026

New FUSILLI tool improves gene fusion detection in pediatric leukemia

Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

15 May 2026

New technology reveals how RNA shapes influence protein production and stability

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Healthy brain maintenance protects cognitive skills from early Alzheimer's effects

A healthy brain may help protect thinking and memory skills from the early effects of Alzheimer's disease, a new study has found.

15 May 2026

PSA tests detect 30 percent more cancers but may cause overtreatment

Blood tests to detect potential signs of prostate cancer likely reduce the risk of dying from prostate cancer, an updated Cochrane review finds. This is a shift from the previous version of the review, which did not find sufficient evidence that screening reduced prostate cancer deaths.

15 May 2026

Can supplements slow Parkinson’s disease? Review reveals where the evidence stands

Dietary supplements are widely used by people with Parkinson’s disease, but this review finds that none have yet been proven to slow disease progression. Biotics, nicotinamide riboside, and omega-3 fatty acids combined with vitamin E show the most promise, but larger, longer, and better-designed trials are needed.

14 May 2026

The Goldilocks sleep zone: study links too little and too much sleep to biological aging

The Nature study introduces “Sleep Chart,” a framework linking self-reported sleep duration with 23 biological aging clocks derived from MRI, plasma proteomics, and metabolomics. Across UK Biobank participants, the lowest biological age gaps generally appeared between 6.4 and 7.8 hours of sleep, while shorter and longer sleep were associated with higher disease and mortality risk.

14 May 2026

How Andes virus super-spreaders reveal the risk behind the MV Hondius hantavirus cluster

A 2020 NEJM study of the 2018 to 2019 Epuyén outbreak showed that Andes virus spread from one zoonotic introduction into four generations of human infection, causing 34 cases and 11 deaths. The findings are newly relevant after WHO reported an ANDV cluster linked to the MV Hondius cruise ship, where close indoor exposure may have enabled onboard human-to-human transmission.

14 May 2026

Perioperative medicine emerges as a system wide strategy for better surgery outcomes

Perioperative medicine is emerging as a transformative, comprehensive, system-wide approach to patient care before, during, and after surgery – that reduces complication rates and hospital days, provides better health outcomes, and improves health system performance, according to a special article in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

14 May 2026

Brain immune cells found to regulate anxiety and grooming behaviors

A study led by a University of Louisville School of Medicine pediatrics and child neurology researcher reveals how a specific signaling mechanism in microglia, the brain's immune cell, can regulate anxiety and grooming behaviors. These behaviors are core symptoms of autism and obsessive-compulsive spectrum disorders.

14 May 2026

Clinical trial challenges long held beliefs about treating brittle bone disease

Increasing bone density in patients with a rare genetic condition that causes bones to break easily does not prevent fractures, a large clinical trial has found.

14 May 2026

Stanford scientists map the molecular diversity of different global populations

Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup - from metabolism and immunity to gut microbiota and biological aging.

14 May 2026

Retinal stimulation via contact lenses effective as antidepressants in mice

Materials scientists have designed brain-stimulating contact lenses that are as effective as Prozac at treating depression in mice. The soft, transparent contact lenses have in-built electrodes that deliver mild electrical signals to the brain via the retina to stimulate specific brain regions associated with depression.

14 May 2026

Study traces adult heart disease risk back to the womb

A child's future heart health may be partially shaped before they are born, reports a new Northwestern Medicine study that found pregnancy complications are linked to poorer cardiovascular health in offspring more than 20 years later.

14 May 2026

Identifying the methodology gap that prevents treatment of infection-triggered chronic diseases

Thousands of Americans develop chronic persistent symptoms-such as fatigue, cognitive difficulties ("brain fog"), and other debilitating issues-each year following acute infections from Lyme disease, COVID-19, and other pathogens. Efforts to identify causes and produce treatments have failed. However, 16 leading researchers think they know part of the problem: study design.

14 May 2026

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Early and accurate prognostic assessment is crucial to prevent disease progression in liver failure. Thyroid hormones (THs), particularly triiodothyronine (T3), are key metabolic regulators and play an important role in liver regeneration. Liver failure is frequently complicated by non‑thyroidal illness syndrome (NTIS), characterized by low T3 with normal or slightly elevated TSH and T4.

14 May 2026

Scientists identify methylphenidate as an effective tool for combating chronic cancer related fatigue

A new meta-analysis in the May 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants-a class of medication that increases dopamine and norepinephrine availability in the brain-can provide meaningful relief for cancer-related fatigue.

14 May 2026

Study reveals how brain cells process vision amidst thousands of synaptic inputs

Even in the primary visual cortex, a brain region named for its specialized role in processing basic features of what the eyes see, not every neuron ends up answering the call to process properties of visual input. Maybe that's because each neuron receives a wide variety of inputs via thousands of circuit connections, or "synapses," and has to opt to respond to the visual information vs. something else.

14 May 2026

A breakthrough molecular discovery could neutralize gluten and protect coeliac patients

A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona (IBMB) of the CSIC (which stands for Consejo Superior de Investigaciones Científicas), has successfully designed and tested a gluten-degrading molecule that is a promising ally in the management of coeliac disease, an autoimmune disease whose symptoms are triggered by the consumption of gluten and other prolamins found in cereals.

14 May 2026

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

Researchers have introduced a novel diagnostic method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

14 May 2026

Medical News

Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

New FUSILLI tool improves gene fusion detection in pediatric leukemia

New technology reveals how RNA shapes influence protein production and stability

Healthy brain maintenance protects cognitive skills from early Alzheimer's effects

PSA tests detect 30 percent more cancers but may cause overtreatment

Can supplements slow Parkinson’s disease? Review reveals where the evidence stands

The Goldilocks sleep zone: study links too little and too much sleep to biological aging

How Andes virus super-spreaders reveal the risk behind the MV Hondius hantavirus cluster

Perioperative medicine emerges as a system wide strategy for better surgery outcomes

Brain immune cells found to regulate anxiety and grooming behaviors

Clinical trial challenges long held beliefs about treating brittle bone disease

Stanford scientists map the molecular diversity of different global populations

Retinal stimulation via contact lenses effective as antidepressants in mice

Study traces adult heart disease risk back to the womb

Identifying the methodology gap that prevents treatment of infection-triggered chronic diseases

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Scientists identify methylphenidate as an effective tool for combating chronic cancer related fatigue

Study reveals how brain cells process vision amidst thousands of synaptic inputs

A breakthrough molecular discovery could neutralize gluten and protect coeliac patients

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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