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Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, according to a new study published January 14, 2026 in the open-access journal PLOS One by Ana Maldonado-Contreras of University of Massachusetts Chan Medical School, U.S., and colleagues.

14 Jan 2026

Study reveals genetic signatures linked to HIV-related cognitive impairment

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

14 Jan 2026

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

AI tool helps clinicians quickly understand complex patient medical histories

An AI-guided platform at Penn Medicine allows clinicians to quickly and easily unearth pertinent information from patients’ electronic health records that otherwise might have been difficult to find.

14 Jan 2026

Dietary intervention eases celiac symptoms in children but not quality of life

The Gluten3S research group launched a dietary intervention with children who had recently been diagnosed with celiac disease.

14 Jan 2026

Hearing aid use has little impact on cognitive test scores

A new study has found that for people with moderate hearing loss, being prescribed hearing aids had little impact on cognitive test scores.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death.

14 Jan 2026

Age-tailored therapies needed for treating the young and old with sepsis

Dealing with an infection isn't as straightforward as simply killing the pathogen. The body also needs to carefully steer and monitor its immune response to prevent collateral damage.

14 Jan 2026

Novel liquid biopsy technology could advance cancer diagnostics and monitoring

A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow.

14 Jan 2026

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation.

14 Jan 2026

Heart failure care gaps found among Asian American ethnic groups

Using nearly a decade of data (2015–2023) from 800+ U.S. hospitals and more than 700,000 patients overall, Northwestern researchers found that when Asian American heart failure patients are separated by ethnicity, rather than grouped together as "Asian," important differences in care emerge across groups including Filipino, Vietnamese, Chinese, Asian Indian, Korean and Japanese patients.

14 Jan 2026

HIF1 protein identified as key driver of tendon pain

Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.

14 Jan 2026

Post-meal blood sugar spikes linked to increased Alzheimer's risk

A new study led by researchers from the University of Liverpool has found that spikes in blood sugar after meals may increase the risk of Alzheimer's disease.

14 Jan 2026

Researchers develop new method to 3D print micrometer-sized structures within cells

Researchers have developed a way to 3D print custom micrometer-sized structures directly into the interior of living cells.

14 Jan 2026

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

14 Jan 2026

Medical News

Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

Study reveals genetic signatures linked to HIV-related cognitive impairment

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

AI tool helps clinicians quickly understand complex patient medical histories

Dietary intervention eases celiac symptoms in children but not quality of life

Hearing aid use has little impact on cognitive test scores

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Age-tailored therapies needed for treating the young and old with sepsis

Novel liquid biopsy technology could advance cancer diagnostics and monitoring

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

Heart failure care gaps found among Asian American ethnic groups

HIF1 protein identified as key driver of tendon pain

Post-meal blood sugar spikes linked to increased Alzheimer's risk

Researchers develop new method to 3D print micrometer-sized structures within cells

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

WSU study reveals gaps in end-of-life care education for doctors

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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