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Philosophical study redefines moral distress in modern healthcare systems

Nurses and physicians often recognize what kind of care a patient deserves in a given moment, be it more time at the bedside, a change in pain management, or a detailed conversation about the goals of a specific treatment.

28 Aug 2026

Aficamten improves symptom burden and exercise capacity in patients with non-obstructive HCM

Aficamten treatment was associated with significant improvements in symptom burden and exercise capacity in patients with symptomatic non-obstructive hypertrophic cardiomyopathy, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

28 Aug 2026

POET-II trial reduces antibiotic duration for infective endocarditis by two weeks

A response-tailored strategy reduced antibiotic duration by two weeks without compromising the safety of patients with left-sided infective endocarditis.

28 Aug 2026

Oral anticoagulants benefit patients with atrial fibrillation at intermediate stroke risk

Oral anticoagulant therapy lowered the risk of adverse clinical events compared with no anticoagulation in patients with atrial fibrillation at intermediate stroke risk, according to results from the SINGLE-AF trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

28 Aug 2026

Younger heart patients benefit from implantable cardioverter-defibrillators in CMR GUIDE trial

An implantable cardioverter-defibrillator did not improve the primary endpoint overall in the CMR GUIDE trial but younger patients appeared to benefit, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in JAMA.

28 Aug 2026

Rapid rise of GLP-1 medicines brings obesity and eating disorders together

Obesity and eating disorders have traditionally been treated as separate areas of healthcare – but the rapid rise of GLP-1 medicines is increasingly bringing the two together.

28 Aug 2026

UCSF scientists build largest molecular interaction map for autism

For more than two decades, researchers have identified hundreds of genes that increase the risk of autism spectrum disorder (ASD).

28 Aug 2026

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Leading African biopharmaceutical company Minapharm Group (www.Minapharm.com), headquartered in Egypt with subsidiaries in Berlin, will receive up to US$16.5 million from the Coalition for Epidemic Preparedness Innovations (CEPI) to advance the development of a Bundibugyo ebolavirus vaccine candidate, strengthening efforts to develop vaccines to combat the fastest-growing and second-largest Ebola outbreak on record affecting the Democratic Republic of the Congo (DRC).

28 Aug 2026

CARDIO-TTRansform trial investigating eplontersen fails to meet primary efficacy endpoint

The CARDIO-TTRansform trial investigating eplontersen in patients with transthyretin-mediated amyloid cardiomyopathy did not meet its primary efficacy endpoint, according to results presented in a Hot Line session today at ESC Congress 2026.

28 Aug 2026

Lysine methylation found to control movement in single-celled parasites

LMU researchers identify a molecular mechanism that enables single-celled parasites to switch on the machinery they need to move and invade host cells.

28 Aug 2026

Major cardiac societies develop and publish a universal definition of myocardial infarction

When a myocardial infarction, such as a heart attack, occurs, being able to classify its type can improve diagnosis and treatment.

28 Aug 2026

First joint guidelines address cardiovascular events and chronic kidney disease

The first-ever European Society of Cardiology Guidelines on the management of cardiovascular disease and chronic kidney disease have been developed in collaboration with the European Renal Association.

28 Aug 2026

New guidelines simplify heart failure phenotypes into two groups

Reflecting improved understanding and treatment advances, new European Society of Cardiology (ESC) Guidelines on heart failure have been published online today in the European Heart Journal and will be presented at ESC Congress 2026 this afternoon.

28 Aug 2026

New international guidelines highlight the extensive benefits of cardiac rehabilitation

The European Society of Cardiology (ESC) Guidelines on cardiac rehabilitation have been published online today in the European Heart Journal.

28 Aug 2026

Study shows how temperature extremes can contribute to heart failure hospitalizations

Heart failure hospitalization risk increases after short-term exposure to cold spells, lower ambient temperatures and higher ambient temperatures, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2026.

28 Aug 2026

Compound PF-04457845 slows motor decline in ALS mouse models

Amyotrophic lateral sclerosis (ALS) is a severe neurological disease that destroys nerve cells responsible for muscle movement.

28 Aug 2026

Probiotics for mental health? A new review finds promising signals and major gaps

This narrative review examines how psychobiotics may influence anxiety, depression, bipolar disorder, and schizophrenia through gut-brain pathways involving neurotransmitters, inflammation, immune regulation, gut barrier function, and stress signaling. Specific Lactobacillus and Bifidobacterium strains showed encouraging effects, but wide differences in strains, doses, populations, and study designs currently limit clinical translation.

28 Aug 2026

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

27 Aug 2026

The US switch in shingles vaccines revealed an unexpected heart health pattern

In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic studies

27 Aug 2026

Birth-related PTSD may go undiagnosed among thousands of new mothers

Tens of thousands of new mums across Britain may be suffering undiagnosed PTSD following childbirth, according to a University of East Anglia report.

27 Aug 2026

Medical News

Philosophical study redefines moral distress in modern healthcare systems

Aficamten improves symptom burden and exercise capacity in patients with non-obstructive HCM

POET-II trial reduces antibiotic duration for infective endocarditis by two weeks

Oral anticoagulants benefit patients with atrial fibrillation at intermediate stroke risk

Younger heart patients benefit from implantable cardioverter-defibrillators in CMR GUIDE trial

Rapid rise of GLP-1 medicines brings obesity and eating disorders together

UCSF scientists build largest molecular interaction map for autism

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

CARDIO-TTRansform trial investigating eplontersen fails to meet primary efficacy endpoint

Lysine methylation found to control movement in single-celled parasites

Major cardiac societies develop and publish a universal definition of myocardial infarction

First joint guidelines address cardiovascular events and chronic kidney disease

New guidelines simplify heart failure phenotypes into two groups

New international guidelines highlight the extensive benefits of cardiac rehabilitation

Study shows how temperature extremes can contribute to heart failure hospitalizations

Compound PF-04457845 slows motor decline in ALS mouse models

Probiotics for mental health? A new review finds promising signals and major gaps

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

The US switch in shingles vaccines revealed an unexpected heart health pattern

Birth-related PTSD may go undiagnosed among thousands of new mothers

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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