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$VT3989 shows promising antitumor activity in refractory mesothelioma patients$

VT3989 shows promising antitumor activity in refractory mesothelioma patients

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led by researchers from The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Proimmune expands into new 18,000 sq ft global headquarters enabling major expansion in immunology and life science innovation

ProImmune Ltd, a global leader in life science reagents and services, today announced the opening of its new global headquarters building at Oasis Park, Oxford, enabling significant expansion of its operations and capacity to serve its global client base.

22 Oct 2025

Despite the hoopla, vaccines should be in reach this cough-and-cold season

For people whose autumn agenda includes getting vaccinated against respiratory diseases — covid, flu, and, for some, RSV — this year may be surprisingly routine.

22 Oct 2025

A new car vs. health insurance? Average family job-based coverage hits $27K

With the federal shutdown entering its fourth week, spurred by a stalemate over the cost of health insurance for 22 million Americans on Affordable Care Act plans, a new report shows that over 154 million people with coverage through an employer also face steep price hikes — and that the situation is likely to get worse.

22 Oct 2025

Night shift work may raise risk of irritable bowel syndrome

The study indicates that night shift work increases irritable bowel syndrome risk, particularly among those with obesity, due to circadian rhythm disturbances.

22 Oct 2025

Researchers seek public help to map the evolution of vivid memories

Do you have a memory so vivid you can relive it as if it's happening all over again, re-experiencing the physical sensations and emotions just as you did in that moment?

22 Oct 2025

Immediate skin-to-skin contact offers significant health advantages for infants

Immediate skin-to-skin contact between newborns and their mothers offers a better start in life, improving a number of key health metrics, according to a newly updated Cochrane review.

22 Oct 2025

AI algorithm proves more accurate than experts in glaucoma detection

While artificial intelligence (AI)-powered screening has been validated for diabetic retinopathy, applying the technology to glaucoma has proved more challenging because glaucoma is not one disease. A glaucoma diagnosis is based on a constellation of symptoms, diagnostic tests, and longitudinal data.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Report maps vaccination's comprehensive benefits for health and economy

A new Gerontological Society of America report, "Concentric Value of Vaccination: Intersecting Health, Economic, and Societal Benefits," provides evidence on the advantages of immunization for individual and population health, economic outcomes, and societal well-being.

22 Oct 2025

Discovery of H2BNTac drives prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Study links child behavior stress and lower self-regulation in parents

Any parent will tell you that raising a child isn't easy. While the experience can be filled with joy and love and fulfilment, emotional, financial and marital stress will present challenges to any family.

22 Oct 2025

Noninvasive optical system measures blood flow with precision

Measuring how well blood flows to the brain is crucial for understanding a wide range of neurological issues, from strokes to migraines to traumatic brain injuries. Obtaining such measurements noninvasively, however, remains a challenge. The scalp and skull not only obstruct viewing the brain directly but also have their own blood supply, further complicating cerebral blood flow measurements.

22 Oct 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025

Tracking daily blood pressure in pregnancy could predict low birth weight sooner

Early-pregnancy home blood pressure patterns reveal that even small cumulative elevations, not just high averages, raise the risk of low birth weight. Tracking daily readings above thresholds may improve early warning and maternal–fetal outcomes.

21 Oct 2025

Gut bacteria found to make serotonin and boost intestinal motility

Researchers have identified Limosilactobacillus mucosae and Ligilactobacillus ruminis as human gut bacteria capable of producing serotonin by decarboxylating 5-hydroxytryptophan (5-HTP). Their activity enhances intestinal motility and enteric nerve density, linking microbial serotonin synthesis to gut function and potential IBS mechanisms.

21 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Strong grip strength lowers risk of organ dysfunction in obesity

People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.

21 Oct 2025

Medical News

VT3989 shows promising antitumor activity in refractory mesothelioma patients

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Proimmune expands into new 18,000 sq ft global headquarters enabling major expansion in immunology and life science innovation

Despite the hoopla, vaccines should be in reach this cough-and-cold season

A new car vs. health insurance? Average family job-based coverage hits $27K

Night shift work may raise risk of irritable bowel syndrome

Researchers seek public help to map the evolution of vivid memories

Immediate skin-to-skin contact offers significant health advantages for infants

AI algorithm proves more accurate than experts in glaucoma detection

Scientists question the safety and efficacy of the diet for metabolic health

Report maps vaccination's comprehensive benefits for health and economy

Discovery of H2BNTac drives prostate tumor growth

Study links child behavior stress and lower self-regulation in parents

Noninvasive optical system measures blood flow with precision

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Tracking daily blood pressure in pregnancy could predict low birth weight sooner

Gut bacteria found to make serotonin and boost intestinal motility

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Strong grip strength lowers risk of organ dysfunction in obesity

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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