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Modified zinc finger scaffold suppresses microglial activation in mouse brain

A KAIST-led research team has found that a protein involved in gene regulation can suppress the harmful aggregation of amyloid-beta, a peptide associated with Alzheimer's disease. The approach also reduced the toxicity of protein aggregates that had already formed.

5 Nov 2026

New tool identifies older adults at risk of delirium and falls from anticholinergic medications

Researchers funded by Health Data Research UK (HDR UK) have developed a new tool to help doctors and pharmacists identify older patients at risk of delirium and serious falls associated with taking multiple anticholinergic medications.

5 Nov 2026

Tau spreads more rapidly in early-onset Alzheimer's disease

Patients with early-onset Alzheimer's disease, whose symptoms start before age 65, have more extensive deposits of tau, a hallmark protein of the condition, compared with patients whose symptoms start at 65-plus, a new study found.

5 Nov 2026

Brain scans reveal clues to Alzheimer's risk years before memory loss begins

Inside the brains of some cognitively normal adults, firing patterns were able to foretell Alzheimer's disease years before the onset of memory loss or the accumulation of plaques and tangles, according to new Stanford Medicine-led research.

5 Nov 2026

Three-drug combination remodels immune environment in gastric cancer

A triplet combination therapy can remodel the tumor microenvironment in patients with advanced gastric cancer and shows a promising safety profile, according to results from a new phase 2 clinical trial.

5 Nov 2026

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

ACS Emergency General Surgery Verification associated with fewer deaths and shorter stays

Patients treated at hospitals that earned American College of Surgeons (ACS) Emergency General Surgery Verification demonstrated lower 30-day death rates and experienced shorter hospital stays after their hospitals earned verification, according to an analysis published in JAMA Surgery.

4 Nov 2026

UCLA advances CRISPR gene-editing therapy for sickle cell disease

A UCLA-led team has described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.

4 Nov 2026

Workplace exposure to petroleum-based lubricants linked to higher MS risk

Exposure to petroleum-derived lubricants at work, including engine oil, hydraulic oil and cutting fluids used to cool or lubricate metal during metalworking, is associated with higher odds of multiple sclerosis (MS), according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026

Longer reproductive lifespan and hormonal history may influence brain vascular health

A longer reproductive lifespan and a history of using birth control pills or menopausal hormone therapy were associated with certain signs of blood vessel health in the brain, according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026

Psychedelics linked to lingering visual disturbances resembling early psychosis

Every night, as he fell asleep, a 25-year-old man saw an eye in his ceiling. It was huge and unblinking, and it felt as if the whole world was being sucked into it.

4 Nov 2026

Bed bug infestations affect communities across all socioeconomic groups

Rather than being a poverty problem, bed bugs are actually everyone's problem.

4 Nov 2026

Women with DCIS may not need routine imaging after double mastectomy

Women who have undergone a double mastectomy to treat ductal carcinoma in situ (DCIS), a noninvasive form of breast cancer also known as stage 0 breast cancer, may not benefit from routine mammograms or other breast imaging after surgery, according to a new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

4 Nov 2026

Rutgers specialist launches awareness initiative for often-misdiagnosed tailbone pain

Thousands of people suffer with tailbone pain, often struggling to find an accurate diagnosis and effective treatment.

4 Nov 2026

Inherited high cholesterol linked to slightly higher pre-eclampsia risk

Women with the inherited cholesterol condition familial hypercholesterolemia may be at a slightly higher risk of developing pre-eclampsia, a pregnancy condition that can cause serious complications, according to a new study in the European Journal of Preventive Cardiology.

4 Nov 2026

Dialysis may not be the default treatment for older kidney patients

Dialysis should not necessarily be regarded as the default option for older people with kidney failure, the first randomized study of its kind in the world, led by the University of Bristol, has found.

4 Nov 2026

Children exposed to cannabis and tobacco before birth scored lower on thinking tests

In an exploratory analysis of 8,706 U.S. children aged 9 to 11, prenatal exposure to both cannabis and tobacco was associated with modestly lower fluid cognition scores compared with cannabis-only exposure or neither substance. Differences from tobacco-only exposure were not statistically significant, nor were differences in crystallized cognition, and the observational findings could not establish causation.

4 Nov 2026

Caffeine intake rises among Korean adults as brewed coffee gains ground

An analysis of 48,991 Korean adults found that average daily caffeine intake from beverages increased between 2016 and 2024, while the odds of consuming at least 400 mg of caffeine on a single day rose by approximately 5% annually. Coffee remained the predominant caffeine source, with a shift from prepared coffee mixes toward brewed coffee and distinct consumption patterns across age groups and sexes.

4 Nov 2026

Modern lifestyles may be changing our gut bacteria in unexpected ways

A global study of 1,015 adults across 12 countries found that industrialized lifestyles were associated with lower gut bacterial diversity, reduced microbial community stability, and increased markers of intestinal stress and immune activity. The researchers also found that a microbiome-based health index developed using industrialized populations performed poorly in less-industrialized communities, raising concerns about its applicability across diverse populations.

4 Nov 2026

A study of 27,000 adults links bean products and soy compounds to lower kidney disease odds

A cross-sectional study of 27,003 adults in Northeast China found that higher consumption of processed bean products and soy isoflavones was associated with lower odds of chronic kidney disease, while plain bean intake showed no significant association. The relationship with soy isoflavones was stronger in women, although the observational findings cannot establish whether these foods protect against kidney disease.

4 Nov 2026