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Disrupted sleep rhythms may increase dementia risk through impaired waste clearance

Why are conditions such as chronic stress, depression, cardiovascular disease, fragmented sleep, and aging all associated with a higher risk of dementia? In a new review piece in Science, University of Rochester Medicine neuroscientist Maiken Nedergaard, MD, DMSc, proposes that many of these seemingly different conditions may converge on the same biological problem: disruption of a sleep-dependent brain rhythm that helps clear waste from the brain.

22 May 2026

ISTA researchers prove keratin is indispensable for coherent cell migration

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

22 May 2026

Study finds widespread hantavirus exposure among Pacific Northwest rodent populations

The Sin Nombre virus – a hantavirus that can cause a deadly respiratory disease in humans – may be more widespread among rodent populations in parts of the Pacific Northwest than previously recognized.

21 May 2026

Excess EXO1 protein may drive cancer DNA damage and treatment response

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

21 May 2026

Study supports routine childhood screening for type 1 diabetes

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care.

21 May 2026

Extreme heat increasingly threatens vulnerable people in the United Kingdom

Older people, care home residents and those living in poor-quality housing are facing growing danger from extreme heat, as new research warns that the UK is failing to protect those most at risk.

21 May 2026

AI-created miniproteins show promise for targeting hard-to-treat diseases

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies - from the ability to see and smell, to sensing of adrenaline, insulin, nutrients and medicines.

21 May 2026

Smartphone overdependence may signal higher alcohol and smoking risk in teens

Higher smartphone overdependence was significantly associated with greater odds of self-reported lifetime alcohol and tobacco use among more than 100,000 Korean adolescents. The study found graded dose-response patterns, with earlier initiation and heavier alcohol or smoking behaviors linked to a higher adjusted probability of high-risk smartphone overdependence.

21 May 2026

High-dose vitamin D3 in pregnancy may boost children’s memory by age 10

High-dose vitamin D3 supplementation from mid-pregnancy to early postpartum was associated with better verbal and visual memory in children at age 10. The post hoc analysis suggests prenatal vitamin D3 exposure may support selected cognitive functions, although findings require cautious interpretation.

21 May 2026

Scientists capture immune cells attacking live melanoma cells in real time

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

21 May 2026

PAHO and The Carter Center join hands on the elimination of onchocerciasis across the Americas

The Pan American Health Organization (PAHO) and The Carter Center signed a Technical Cooperation Agreement today to strengthen collaboration on the elimination of onchocerciasis — also known as river blindness — and other communicable diseases in the Americas.

21 May 2026

Cycling may significantly improve brain health and well-being

A new peer-reviewed publication published in Frontiers in Sports and Active Living, highlights bicycling as a powerful, accessible tool for improving brain health and overall well-being.

21 May 2026

Oral drug improves platelet recovery during chemotherapy in gastrointestinal cancer patients

An oral medication already approved for thrombocytopenia in patients with liver disease significantly improved platelet recovery and helped patients with gastrointestinal cancers maintain platelet counts needed to continue chemotherapy as scheduled, according to results from a phase 2 clinical trial led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, and Mass General Hospital.

21 May 2026

Experimental virus therapy targets resistant high-grade neuroendocrine tumors

A phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against aggressive neuroendocrine tumors that often resist treatment.

21 May 2026

Artificial intelligence-based tool could improve multiple myeloma treatment decisions

An artificial intelligence-based tool may help physicians determine which newly diagnosed multiple myeloma patients are most likely to benefit from specific therapies, including immunotherapy and stem cell transplantation.

21 May 2026

Specific gene fusion patterns tied to solitary fibrous tumor outcomes

Specific genetic fusion patterns in solitary fibrous tumors may help identify which patients face a higher risk of metastasis, recurrence and more aggressive disease behavior, according to new research that could improve how physicians assess and eventually treat this rare cancer.

21 May 2026

New eye drop formulation shows promise for dry eye disease

Researchers at Baylor College of Medicine and Okayama University in Japan have developed and tested in mice a promising new eye drop formulation for treating dry eye disease.

21 May 2026

Vitamin B12 analog targets deadly brain cancer cells

A new research paper was published in Volume 13 of Oncoscience on April 2, 2026, titled "Selective blood–brain barrier penetration and tumor targeting of nitrosylcobalamin in glioblastoma: Pharmacokinetics, tissue distribution, and synergistic activity with trail and temozolomide."

21 May 2026

Researchers discover unexpected cellular triggers for precancerous pancreas lesions

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer.

21 May 2026

NHS cost to treat youth mental health crises quadruples over a decade

The annual cost to the NHS to treat children and young people experiencing a mental health crisis in specialised acute hospital wards in England quadrupled to £87.5 million between 2012 and 2022, finds a new study led by UCL researchers.

21 May 2026