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Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study found.

19 Nov 2025

Automated system relies on imaging droplets of biofluids for disease diagnosis

Not long ago, the idea of diagnosing a disease with a droplet of blood was considered a pipe dream. Today, this technology could soon become a reality.

19 Nov 2025

Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance

Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction of patients.

19 Nov 2025

Integrated financial and mental health programs offer stronger benefits

Supporting people with both financial and mental health support at the same time works better than tackling either one in isolation, according to new research led by the London School of Economics and Political Science (LSE).

19 Nov 2025

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Pertussis, or whooping cough, remains a highly contagious respiratory infection caused by Bordetella pertussis. Despite inclusion of pertussis vaccines in immunization programs since the 1970s, outbreaks have re-emerged globally due to waning immunity and bacterial evolution.

19 Nov 2025

Herbal garlic mouthwash emerges as a potential alternative to chlorhexidine

Garlic extract demonstrates antimicrobial efficacy comparable to other widely used antiseptics and disinfectants, such as chlorhexidine, according to University of Sharjah medical scientists.

19 Nov 2025

Clogged brain drains may signal early Alzheimer's risk

"Drains" in the brain, responsible for clearing toxic waste in the organ, tend to get clogged up in people who show signs of developing Alzheimer's disease, a study by researchers from Nanyang Technological University, Singapore (NTU Singapore) has discovered.

19 Nov 2025

AI analysis of biopsy slides predicts rectal cancer treatment response

Artificial intelligence (AI) can predict how well patients with rectal cancer will respond to treatment by analyzing standard tissue samples taken during diagnosis, finds a new study from researchers at UCL and UCLH.

19 Nov 2025

Generative AI tool enhances accuracy in detecting abnormal blood cells

An AI tool that can analyze abnormalities in the shape and form of blood cells, and with greater accuracy and reliability than human experts, could change the way conditions such as leukemia are diagnosed.

19 Nov 2025

Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies

An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI.

19 Nov 2025

Researchers develop new method to combat antibiotic-resistant bacteria using bacteriophages

Antibiotic resistance is one of the most pressing challenges to global public health as harmful microbes evolve to evade these medications.

19 Nov 2025

New clinical trial shows promise for shorter TB treatment

New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."

19 Nov 2025

Longest survival in the world reported to date for multiple myeloma patients

Berenson Cancer Center published survival data analyzed by the Institute for Myeloma & Bone Cancer Research of 175 consecutive and unselected patients with multiple myeloma in the journal Haematologica.

19 Nov 2025

Primerdesign launches exsig Mag RapidBead Pro Extraction kit for DNA and RNA

Primerdesign (part of the Novacyt Group), a company focused on the design, manufacture, validation and supply of real-time PCR kits and reagents, today announced the launch of its exsig® Mag RapidBead Pro Extraction kit.

19 Nov 2025

Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

A hidden health crisis following natural disasters: Mold growth in homes

After returning from what felt like the best internship of her life, Danae Daniels was excited to unwind and settle into a new semester at Florida Agricultural and Mechanical University.

19 Nov 2025

Blood group A linked to a higher risk of primary biliary cholangitis

Findings indicate blood group A elevates the risk of primary biliary cholangitis, suggesting ABO group analysis could aid in autoimmune liver disease diagnosis.

19 Nov 2025

BMI is failing to detect dangerous obesity as people age

A landmark study finds waist-to-height ratio more effective than BMI in identifying obesity risk, as central fat levels rise across the UK population.

19 Nov 2025

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

18 Nov 2025

Blocking mir-21 shows promise for slowing bladder cancer growth

Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal surgery, and despite advances in systemic therapies, recurrence is frequent in the most aggressive forms of the disease.

18 Nov 2025