Breast Cancer

Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare.

HER-2 Positive Breast Cancer

Human epidermal growth factor receptor 2 (HER2) is a gene that can play an important role in the development of some types of breast cancer. This gene is also sometimes referred to as Erc-B2 receptor tyrosine kinase 2 (ERBB2). This gene is involved in the production of HER2 proteins, which are present on breast cells as receptors to control the growth, division, and repair of the cells.

Surgery for Breast Cancer

Breast Cancer Causes

Breast Cancer Society and Culture

What are Aromatase Inhibitors?

History of Breast Cancer

What is a Mammary Gland?

Hormone Receptor Positive Breast Cancer

Breast Cancer Diagnosis

Breast Cancer Prognosis

What Does a Quadrantectomy Involve?

Gail Model (Breast Cancer Risk Assessment Tool)

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Living with Breast Cancer

Thermography versus Mammography: Which is Best?

Breast Cancer Pathophysiology

Breast Cancer Screening

What is the HER2 Gene?

Radial Scar of the Breast

Microwave Imaging for Breast Cancer Versus X-Ray Mammograms

Chemotherapy for Breast Cancer

What is the BRCA2 Gene?

Familial Breast Cancer

Breast Cancer Management

Breast Cancer Awareness

What is the BRCA1 Gene?

Treating Breast Cancer Using Antibiotics

PARP Inhibitors For Hard-To-Treat Cancers

Detecting breast cancer in dense breasts

Axillary Lymph Nodes and Breast Cancer

Post-Mastectomy Pain

What is Breast Reconstruction?

What is Triple Negative Breast Cancer?

What Does a Sentinel Node Biopsy Involve?

Preventing Breast Cancer

Intraductal Papilloma - Benign Tumors of the Breast

Sentinel Lymph Nodes

What is Ductal Carcinoma in Situ (DCIS)?

Radial Scar Diagnosis and Management

What is Invasive Ductal Breast Cancer?

Microwave Imaging for Breast Cancer: Procedure

Axillary Sampling and Sentinel Node Biopsy Comparison

Microcalcifications in Breast Cancer

A Guide to Checking your Breasts for Lumps

What is Metastatic Breast Cancer?

Breast Cancer Symptoms

Treating Breast Oil Cysts

Pathophysiology of the Link Between Obesity and Breast Cancer

The Importance of Hormone Status in Breast Cancer: A Guide to Hormone Dependent Breast Cancer (HDBC)

Breast Cancer Epidemiology

Genetics of Breast Cancer

What is Breast Cancer?

Types of Breast Cancer

Breast Cancer Classification

Radiotherapy for Breast Cancer

Latest Breast Cancer News and Research

Preoperative MRI offers no survival benefit for early-stage breast cancer patients

Patients with stage 1 or 2, hormone receptor (HR)-negative breast cancer had similar five-year rates of locoregional recurrence whether or not they underwent preoperative breast magnetic resonance imaging (MRI) in addition to diagnostic mammography to determine the extent of their cancer, according to results from the phase III Alliance A011104/ACRIN 6694 clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

More AI explanations can reduce accuracy in cancer diagnosis

In recent years AI has emerged as a powerful tool for analyzing medical images. Thanks to advances in computing and large medical datasets from which AI can learn, it has proven to be a valuable aid in reading and analyzing patterns in X-rays, MRIs and CT scans, enabling doctors to make better and faster decisions, particularly in the treatment and diagnosis of life-threatening diseases like cancer.

11 Dec 2025

Breast arterial calcification on mammograms predicts future heart risk

Routine mammograms are a critical tool for breast cancer screening. However, they may also hold crucial, potentially untapped information about a person's risk for cardiovascular disease, the number one cause of death among adults.

11 Dec 2025

Cleveland Clinic reports promising results for breast cancer vaccine from final Phase 1 data

Cleveland Clinic researchers are presenting final Phase 1 data from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.

11 Dec 2025

Preoperative radiation may enhance treatment response in patients with HR-positive, HER2-negative breast cancer

Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led to improved treatment responses prior to surgery, according to the results of the phase II P-RAD clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

Skipping sentinel lymph node biopsy may be safe for some early-stage breast cancer patients

Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median five years of follow-up, according to results from the BOOG 2013-08 phase III clinical trial, presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

An artificial intelligence (AI) model created by integrating clinical, molecular, and histopathological data significantly improved recurrence risk stratification in hormone receptor (HR)-positive, HER2-negative breast cancer, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending time off chemotherapy, according to results from the phase III clinical trial HER2CLIMB-05 presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Next-generation oral SERD therapy lowers the risk of breast cancer recurrence

In an international study led by UCLA, researchers have shown that giredestrant, a next-generation oral selective estrogen receptor antagonist and degrader (SERD), when given as an adjuvant therapy for early-stage (1-3) hormone receptor (HR)-positive, HER2-negative breast cancer, significantly lowered the risk of the disease returning when compared with standard hormone therapies long considered the backbone of treatment.

10 Dec 2025

Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.

10 Dec 2025

AI-driven method uncovers genetic interactions that fuel cancer progression

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.

9 Dec 2025

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.

5 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen receptor-positive or luminal breast cancer.

4 Dec 2025

Remote group cognitive rehab shows promise for easing chemobrain in cancer survivors

A new study examined CRAFT-G, a remote group intervention combining cognitive training, psychoeducation, and occupational-therapy-based strategies for adults experiencing cancer-related cognitive impairment.

4 Dec 2025

New investment aims to accelerate treatments for low-grade brain tumors

Researchers focused on accelerating and testing new treatments for low-grade brain tumors are set to receive a transformative £2.8 million to drive their future work.

3 Dec 2025

Breast cancer reshapes lymphatic vessels to support its spread

Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body.

3 Dec 2025

Trump wants Americans to make more babies. Critics say his policies won’t help raise them.

Maddy Olcott plans to start a career once she graduates from college. But the junior at the State University of New York-Purchase College is so far not planning to start a family — even with the Trump administration dangling inducements like thousand-dollar "baby bonuses" or cheaper infertility drugs.

3 Dec 2025

Automated EHR system triages cancer symptoms, improves care team efficiency

For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.

3 Dec 2025

Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in post-menopausal women with obesity.

2 Dec 2025