Breast Cancer News and Research

Latest Breast Cancer News and Research

Cleveland Clinic reports promising results for breast cancer vaccine from final Phase 1 data

Cleveland Clinic researchers are presenting final Phase 1 data from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.

11 Dec 2025

Preoperative radiation may enhance treatment response in patients with HR-positive, HER2-negative breast cancer

Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led to improved treatment responses prior to surgery, according to the results of the phase II P-RAD clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

Skipping sentinel lymph node biopsy may be safe for some early-stage breast cancer patients

Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median five years of follow-up, according to results from the BOOG 2013-08 phase III clinical trial, presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

An artificial intelligence (AI) model created by integrating clinical, molecular, and histopathological data significantly improved recurrence risk stratification in hormone receptor (HR)-positive, HER2-negative breast cancer, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending time off chemotherapy, according to results from the phase III clinical trial HER2CLIMB-05 presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Next-generation oral SERD therapy lowers the risk of breast cancer recurrence

In an international study led by UCLA, researchers have shown that giredestrant, a next-generation oral selective estrogen receptor antagonist and degrader (SERD), when given as an adjuvant therapy for early-stage (1-3) hormone receptor (HR)-positive, HER2-negative breast cancer, significantly lowered the risk of the disease returning when compared with standard hormone therapies long considered the backbone of treatment.

10 Dec 2025

Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.

10 Dec 2025

AI-driven method uncovers genetic interactions that fuel cancer progression

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.

9 Dec 2025

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.

5 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen receptor-positive or luminal breast cancer.

4 Dec 2025

Remote group cognitive rehab shows promise for easing chemobrain in cancer survivors

A new study examined CRAFT-G, a remote group intervention combining cognitive training, psychoeducation, and occupational-therapy-based strategies for adults experiencing cancer-related cognitive impairment.

4 Dec 2025

New investment aims to accelerate treatments for low-grade brain tumors

Researchers focused on accelerating and testing new treatments for low-grade brain tumors are set to receive a transformative £2.8 million to drive their future work.

3 Dec 2025

Breast cancer reshapes lymphatic vessels to support its spread

Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body.

3 Dec 2025

Trump wants Americans to make more babies. Critics say his policies won’t help raise them.

Maddy Olcott plans to start a career once she graduates from college. But the junior at the State University of New York-Purchase College is so far not planning to start a family — even with the Trump administration dangling inducements like thousand-dollar "baby bonuses" or cheaper infertility drugs.

3 Dec 2025

Automated EHR system triages cancer symptoms, improves care team efficiency

For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.

3 Dec 2025

Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in post-menopausal women with obesity.

2 Dec 2025

Cell nucleus shape plays a key role in cancer therapy outcomes

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden.

2 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

Study highlights a rising incidence of breast cancers in younger women

A study of data from seven outpatient facilities in the New York region found that 20-24% of all the breast cancers diagnosed during an 11-year period were found in women age 18 to 49, according to research being presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2025

Breast Cancer News and Research

Latest Breast Cancer News and Research

Cleveland Clinic reports promising results for breast cancer vaccine from final Phase 1 data

Preoperative radiation may enhance treatment response in patients with HR-positive, HER2-negative breast cancer

Skipping sentinel lymph node biopsy may be safe for some early-stage breast cancer patients

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Next-generation oral SERD therapy lowers the risk of breast cancer recurrence

Machine learning models can help diagnose ALS earlier from a blood sample

AI-driven method uncovers genetic interactions that fuel cancer progression

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

Remote group cognitive rehab shows promise for easing chemobrain in cancer survivors

New investment aims to accelerate treatments for low-grade brain tumors

Breast cancer reshapes lymphatic vessels to support its spread

Trump wants Americans to make more babies. Critics say his policies won’t help raise them.

Automated EHR system triages cancer symptoms, improves care team efficiency

Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

Cell nucleus shape plays a key role in cancer therapy outcomes

Machine learning tool identifies compounds that induce cancer cells into senescence

Study highlights a rising incidence of breast cancers in younger women

Industry Focus eBook - Oncology (1st Edition) eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Breast Cancer News and Research

Latest Breast Cancer News and Research

Industry Focus eBook - Oncology (1st Edition) eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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