Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials.

24 Jun 2025

New PET/CT imaging technique enables early detection of multiple forms of cardiomyopathy

A new PET/CT imaging technique that visualizes activated fibroblasts in the heart muscle enables early detection of multiple forms of cardiomyopathy, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

Study: Intravenous rehydration ‘safe’ for severely malnourished children

Children with critical levels of malnutrition can be safely rehydrated intravenously, according to a new study that calls for a review of the existing global treatment guidelines.

24 Jun 2025

Study identifies potential way to slow or block progression of age-related macular degeneration

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in people over age 50.

24 Jun 2025

New expandable heart valve offers hope for young children with heart defects

Researchers at the University of California, Irvine have successfully performed preclinical laboratory testing of a replacement heart valve intended for toddlers and young children with congenital cardiac defects, a key step toward obtaining approval for human use.

23 Jun 2025

Pregnancy complications linked to higher long-term stroke risk in women

Women who experience complications during pregnancy face a higher risk of stroke in the following decades according to research published in the European Heart Journal today (Tuesday).

23 Jun 2025

Capsule sponge test offers less invasive option for monitoring Barrett's esophagus

Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett's esophagus, a known precursor to esophageal cancer, according to a new study from researchers at the University of Cambridge, Addenbrooke's Hospital and Queen Mary University of London.

23 Jun 2025

Cagrilintide and semaglutide together drive record weight loss in global trial

A 68-week phase 3 trial found that coadministered cagrilintide and semaglutide led to significant and clinically meaningful weight loss in adults with obesity but no diabetes. The combination outperformed either drug alone and improved multiple cardiometabolic health markers.

23 Jun 2025

Amycretin delivers unprecedented weight loss in early trial for obesity treatment

Once-weekly amycretin, a novel peptide activating GLP-1, amylin, and calcitonin receptors, produced rapid, substantial, and sustained weight loss in adults with overweight or obesity during a phase 1b/2a trial. The treatment was generally well tolerated, with mostly mild to moderate gastrointestinal side effects, supporting further investigation in larger, longer studies.

23 Jun 2025