How is Acid Reflux Diagnosed?

Heartburn is a symptom that is often indicative of an underlying condition of acid reflux or Gastro-esophageal reflux disorder. Diagnosis of heartburn is vital as its symptoms are similar to that of a heart attack or other chest pathologies.

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Diagnosis of heartburn or acid reflux disorder includes the following.

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Medical history

This involves taking a detailed assessment of the condition in the past of its presence in the family. History of intake of certain drugs (like pain relievers) or other conditions that may raise the risk of acid reflux like smoking and alcoholism is important.

Factors that aggravate the condition including lying down, taking spicy or fatty foods etc. are noted. Factors that relieve the condition like intake of food or water are also enquired about.

Physical examination

Physical examination looks for features like anemia, weight loss and malnutrition due to difficulty in swallowing. Reflux of acid may also result in complications of lungs like lung abscess, pneumonia and interstitial pulmonary fibrosis.

Ruling out other conditions

Heartburn may also be caused by heart attacks, rib injury, esophagitis due to swallowed corrosives or drugs like NSAIDS, peptic ulcer, infections in HIV positive and other immune-suppressed patients due to herpes, candida, cytomegalovirus, etc. These need to be ruled out.

Heartburn, Acid Reflux, GERD-Mayo Clinic


Endoscopy is the next step. In this an instrument called the endoscope examines the insides of the esophagus. This is a long thin flexible tube with a camera on its tip. The camera sends images of the examined area to the external monitor.

The endoscope is inserted into the mouth and passed into the esophagus. The endoscope checks the insides of the esophagus for possible irritation and inflammation caused by the refluxed acid.


Acid reflux may also be diagnosed using manometry. Manometry is suggested if endoscopy does not find any evidence of damage to the esophagus. This test assesses the strength of the lower esophageal sphincter (LES). It measures the pressure levels inside the sphincter muscle.

A small tube is passed into the esophagus up to the LES. The tube contains a number of pressure sensors that are connected to an external computer. The patient is then given some food and drink to swallow and the pressure at the LES is recorded.

pH monitoring

A 24-hour period of pH monitoring may be recommended. The lower the pH level within the esophagus, the greater the acid content.

Barium swallow test

A Barium swallow test may be advised to check on the blockages or problems with the muscles used during swallowing.

Routine blood tests

Routine blood tests are prescribed. This helps to detect anemia caused due to malnutrition.

Further Reading

Last Updated: Nov 10, 2022

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.


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