Parkinson's Disease

This hub offers a comprehensive exploration of Parkinson’s disease, integrating the latest scientific understanding, clinical practice, and emerging research. The linked articles cover the fundamentals of Parkinson’s disease pathophysiology, diagnosis, treatment strategies, and prognosis, while also examining associated conditions, genetic factors, and disease-modifying therapies. Readers will find evidence-based guidance on symptom management, including motor and non-motor features, along with in-depth discussions on neuroprotective interventions, the gut-brain axis, and the role of comorbidities. The collection also addresses the psychosocial impact of Parkinson’s disease, support resources, and advances in experimental therapies. Whether you are a healthcare professional, researcher, patient, or caregiver, these resources provide authoritative insights into the complex landscape of Parkinson’s disease.

Does Exercise Slow Parkinson's Disease Progression?

A growing pool of evidence suggests that high-intensity physical exercise may have beneficial outcomes in PD patients.

Parkinson's Disease Support

Estrogen as a Treatment for Parkinson’s Disease

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Impact of COVID-19 on Parkinson's Disease

Developing Drugs for Neurodegenerative Diseases

Parkinson’s Disease and Sleeping Disorders

Parkinson's Disease and Helicobacter Pylori

Parkinson's Disease Prognosis

Physiotherapy for Parkinson's Disease

Parkinson's Disease Treatment

Human brain may stay active for hours after death

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Bipolar Disorder and Parkinson’s

Progressive Supranuclear Palsy (PSP) Versus Parkinson's Disease

VPS35 Gene and Parkinson's Disease

Gut Bacteria Affecting Parkinson’s Treatment

Mythbusting: Misconceptions surrounding Parkinson’s Disease

Parkinson's Disease Research

Identifying Early Symptoms in Parkinson’s

Gut-Brain Axis and Neurodegenerative Disorders

Thalamotomy, Pallidotomy and Subthalamotomy

Where Does Parkinson’s Disease Originate?

Parkinson's Disease Pathophysiology

Parkinson's Disease History

Neurophysiotherapy for Parkinson's Disease

Parkinson's Disease and the Gut Microbiome

Parkinson's Disease Diagnosis

Gene Therapies for Parkinson’s Disease

Uncovering Hidden Symptoms: Hallucinations and Delusions in Parkinson’s Disease

What is Parkinson's Disease?

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Is Appendectomy Linked to Parkinson’s Disease?

Parkinsonism in Spinocerebellar Ataxia

Herpes Virus and Parkinson's Disease

Latest Parkinson's Disease News and Research

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T cell therapy for multiple myeloma share a common immune root cause, are associated with high rates of death unrelated to cancer relapse-primarily infection-and may be avoidable.

8 Dec 2025

CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

5 Dec 2025

Researchers highlight five pathways through which microplastics can harm the brain

Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain.

5 Dec 2025

Protein tied to ALS and dementia plays a role in regulating DNA mismatch repair

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process essential for replicating genetic information and cell health.

2 Dec 2025

Untreated restless legs syndrome may increase Parkinson's disease risk

Restless legs syndrome (RLS) is a common neurological sleep disorder characterized by an uncontrollable urge to move the legs, often worsening at night.

2 Dec 2025

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Head trauma impairs brain waste clearance in professional fighters

The brain's waste-clearing system significantly declines in function with repeated head impacts, according to a new study of cognitively impaired professional boxers and mixed martial arts fighters. The findings will be presented next week at the annual meeting of the Radiological Society of North America.

26 Nov 2025

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.

25 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Swallowing difficulties, or dysphagia, affect up to 80% of people with Parkinson's disease and can lead to serious complications, including malnutrition, aspiration and reduced quality of life.

24 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

New study links untreated sleep apnea to higher Parkinson’s disease risk

New research reveals that people with untreated obstructive sleep apnea have a higher risk of developing Parkinson's disease. However, they can significantly reduce the risk by improving the quality of their sleep by using continuous positive airway pressure, or CPAP.

24 Nov 2025

Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

Deep brain stimulation for treatment-resistant severe depression shows positive results

Deep brain stimulation – implants in the brain that act as a kind of 'pacemaker' – has led to clinical improvements in half of the participants with treatment-resistant severe depression in an 'open label' trial.

18 Nov 2025

Brain recordings reveal short-lived effects of tirzepatide on food cravings

A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brain's "reward center" thought to be involved in food noise – but only temporarily.

17 Nov 2025

Dysfunctional mitochondria shown to initiate the onset of Parkinson's

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease.

17 Nov 2025

Study highlights need for XDP specific diagnostic assays

Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects primarily men of Filipino ancestry.

17 Nov 2025

What the air you breathe may be doing to your brain

For years, the two patients had come to the Penn Memory Center at the University of Pennsylvania, where doctors and researchers follow people with cognitive impairment as they age, as well as a group with normal cognition.

12 Nov 2025

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

In a new Northwestern Medicine study, scientists have developed a more precise genetic risk score to determine whether a person is likely to develop arrhythmia, an irregular heartbeat that can lead to serious conditions such as atrial fibrillation (AFib) or sudden cardiac death.

11 Nov 2025