Parkinson's Disease

This hub offers a comprehensive exploration of Parkinson’s disease, integrating the latest scientific understanding, clinical practice, and emerging research. The linked articles cover the fundamentals of Parkinson’s disease pathophysiology, diagnosis, treatment strategies, and prognosis, while also examining associated conditions, genetic factors, and disease-modifying therapies. Readers will find evidence-based guidance on symptom management, including motor and non-motor features, along with in-depth discussions on neuroprotective interventions, the gut-brain axis, and the role of comorbidities. The collection also addresses the psychosocial impact of Parkinson’s disease, support resources, and advances in experimental therapies. Whether you are a healthcare professional, researcher, patient, or caregiver, these resources provide authoritative insights into the complex landscape of Parkinson’s disease.

Does Exercise Slow Parkinson's Disease Progression?

A growing pool of evidence suggests that high-intensity physical exercise may have beneficial outcomes in PD patients.

Parkinson's Disease Diagnosis

Human brain may stay active for hours after death

Parkinson's Disease Support

Parkinson's Disease History

Parkinson's Disease Prognosis

Progressive Supranuclear Palsy (PSP) Versus Parkinson's Disease

Parkinson's Disease Treatment

Parkinson's Disease and Helicobacter Pylori

Parkinsonism in Spinocerebellar Ataxia

Neurophysiotherapy for Parkinson's Disease

What is Parkinson's Disease?

See more featured articles »

Uncovering Hidden Symptoms: Hallucinations and Delusions in Parkinson’s Disease

Parkinson's Disease Pathophysiology

Where Does Parkinson’s Disease Originate?

Is Appendectomy Linked to Parkinson’s Disease?

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Impact of COVID-19 on Parkinson's Disease

Gut-Brain Axis and Neurodegenerative Disorders

Thalamotomy, Pallidotomy and Subthalamotomy

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

VPS35 Gene and Parkinson's Disease

Gut Bacteria Affecting Parkinson’s Treatment

Herpes Virus and Parkinson's Disease

Identifying Early Symptoms in Parkinson’s

Mythbusting: Misconceptions surrounding Parkinson’s Disease

Estrogen as a Treatment for Parkinson’s Disease

Parkinson's Disease Research

Bipolar Disorder and Parkinson’s

Gene Therapies for Parkinson’s Disease

Parkinson’s Disease and Sleeping Disorders

Physiotherapy for Parkinson's Disease

Parkinson's Disease and the Gut Microbiome

Developing Drugs for Neurodegenerative Diseases

Latest Parkinson's Disease News and Research

Stem cell-derived dopaminergic cell transplantation shows encouraging results for Parkinson's disease

The International Society for Stem Cell Research (ISSCR) today announced the presentation of new clinical data from the STEM-PD Phase I/II clinical trial at the ISSCR 2026 Annual Meeting.

9 Jul 2026

Clinical trial finds stem cell brain transplants feasible for Parkinson's disease

A landmark study led from Lund, Sweden, has shown that transplanting stem-cell derived dopamine progenitor cells into the brain is feasible.

9 Jul 2026

Early-onset dementia lowers work productivity years before formal diagnosis

People diagnosed with early-onset dementia had reduced work productivity up to 15 years before diagnosis, according to a study published July 8, 2026, in Neurology, the medical journal of the American Academy of Neurology.

9 Jul 2026

Study identifies new target for Parkinson's disease neuroprotection

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than ten million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.

8 Jul 2026

Hypoxia therapy shows promise for treating mitochondrial brain disorders

Oxygen isn't always a good thing. Of course, people-and most organisms-cannot live without it. But oxygen can also be quite toxic and lead to profound health consequences.

8 Jul 2026

NFL players have higher rates of neurodegenerative disease-caused mortality

Mass General Brigham, Boston University, and the Concussion & CTE Foundation cohort study of nearly 20,000 NFL players reveals that players are dying of dementia and Parkinson's disease at much higher rates than the general population.

8 Jul 2026

Tears may reveal important clues about a person's neurological health

A few tears may someday reveal important clues about a person's neurological health. Researchers reporting in ACS Omega developed a low-cost electrochemical sensor designed to detect dopamine, a neurotransmitter involved in movement, learning, motivation, and emotional regulation.

8 Jul 2026

New framework aligns neural implants with user's needs

Gabriel Lázaro-Muñoz, PhD, JD, and Amanda R. Merner, PhD, of the Health Technology Performance Lab within the Mass General Brigham Neuroscience Institute, are the authors of a paper published in The American Journal of Psychiatry, "Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges."

8 Jul 2026

Study uncovers genetic clues behind sex differences in Parkinson's disease

New research presented today (Wednesday) at the Federation of European Neuroscience Societies (FENS) Forum 2026 has discovered some of the genetic changes in brain cells that may help to explain why more men than women develop Parkinson's disease.

7 Jul 2026

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026

Short sleep and poor sleep quality track with Parkinson’s risk

Using CHARLS data from 2011 to 2020, researchers found that sleep duration and self-reported sleep quality were associated with Parkinson’s disease risk in middle-aged and older Chinese adults. Short sleep was linked to higher PD risk, while age-specific patterns suggested a linear association in adults aged ≤60 years and a U-shaped relationship in those aged >60 years.

6 Jul 2026

Study identifies promising drug target to prevent neurodegenerative conditions

6 Jul 2026

Blood circRNAs may predict Alzheimer’s before symptoms emerge

Blood-based circular RNAs showed strong potential for identifying biomarker-confirmed Alzheimer’s disease and predicting progression to symptomatic disease. When combined with pTau217, the circRNA model produced the strongest predictive performance, but larger prospective validation is still needed.

2 Jul 2026

Smart prodrug targets Alzheimer's disease using hydrogen peroxide signals

A substance that worsens dementia has become a "switch" that initiates treatment. KAIST researchers have developed a new therapeutic approach that uses hydrogen peroxide (H₂O₂), a reactive oxygen species that damages cells and increases in the brains of patients with Alzheimer's disease, to activate a drug selectively in diseased brain tissue.

1 Jul 2026

Study finds early-onset Parkinson’s burden has more than doubled worldwide

A GBD 2021 analysis of 204 countries and territories found that early-onset Parkinson’s disease burden among people aged 20 to 49 more than doubled from 1990 to 2021. Age-standardized incidence, prevalence, and disability rates rose globally, with higher estimated burden among males, rapid growth in middle and high-middle SDI regions, and moderate ecological correlations with pesticide use.

1 Jul 2026