Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Type 1 Diabetes Prevention

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Research

Type 1 Diabetes Treatment

Type 1 Diabetes Cure

Latest Type 1 Diabetes News and Research

UCF researcher explores insulin signaling as new target for diabetic neuropathy

Neuropathy – chronic pain, numbness and tingling in the hands and feet – is a challenging fact of life for many patients with Type 1 diabetes.

2 Mar 2026

Forecasting disease intensity through genomic risk

Approximately 60,000 Danes live with chronic inflammatory bowel disease. Some experience limited discomfort, while others go through a debilitating disease course involving surgery and a stoma. Add to this the fear of leaving home due to urgent toilet needs.

2 Mar 2026

Researchers show red blood cells drive better glucose tolerance at high altitude

Chronic hypoxia improves glucose tolerance in mice through insulin-independent mechanisms, with red blood cells acting as a major systemic glucose sink. Increased erythrocyte production and altered glycolytic flux help reduce circulating glucose while supporting oxygen delivery to tissues.

22 Feb 2026

New technique synthesizes non-natural amino acids for advanced peptide therapeutics

Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just one in a rapidly growing class of drugs called peptide therapeutics that sits between small molecules (like aspirin) and biologics (like antibodies).

20 Feb 2026

Genome sequencing data reveals new insights into Epstein-Barr virus immunity

The Epstein-Barr virus (EBV) can cause certain types of cancer or autoimmune diseases, but how the body controls this common viral infection is largely unknown.

19 Feb 2026

Cyborg transplants may advance cell-based therapies for diabetes

A new electronic implant system can help lab‑grown pancreatic cells mature and function properly, potentially providing a basis for novel, cell-based therapies for diabetes.

19 Feb 2026

Macrophage immune memory depends on lingering interferon gamma

Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind during previous infections.

18 Feb 2026

Metformin linked to lower odds of intermediate macular degeneration in people with diabetes

A five-year image-based study in people with type 2 diabetes found metformin use was associated with lower odds of developing intermediate age-related macular degeneration. The observational findings suggest a potential protective link but do not establish causation and warrant prospective clinical trials.

4 Feb 2026

Implantable immune scaffold predicts type 1 diabetes weeks before symptoms

The study highlights a presymptomatic phase in type 1 diabetes progression, using immune niches to track immune changes before blood sugar abnormalities.

4 Feb 2026

Umbilical cord blood markers may predict future type 1 diabetes

One day, there could be a new test to screen for type 1 diabetes, now that scientists have found markers in the blood of the umbilical cords of children who were later diagnosed with the disease.

29 Jan 2026

Redefining early detection for type 1 diabetes

Researchers have identified a protein pattern that, already at birth, looks markedly different in those who later go on to develop type 1 diabetes. The findings show that a combination of several factors during pregnancy increases the risk of the child later developing the disease. The study is published in Nature Communications and was led by researchers at Linköping University, Sweden, and the University of Florida, USA.

28 Jan 2026

UVA Data Science researcher leads $4.7M project for AI-powered diabetes management

University of Virginia School of Data Science researcher Heman Shakeri has been awarded a major new research grant to lead work at the intersection of machine learning and diabetes care.

27 Jan 2026

Nutrition experts call for dietary fiber recognition as an essential nutrient

Ōtākou Whakaihu Waka nutrition experts are calling for dietary fiber to be officially recognized internationally as an essential nutrient - the first 'new' essential nutrient in more than 50 years.

21 Jan 2026

Landmark UK study supports nationwide screening for childhood type 1 diabetes

A landmark UK study involving tens of thousands of families has shown that childhood screening for type 1 diabetes is effective, laying the groundwork for a UK-wide childhood screening program.

20 Jan 2026

COVID-19 severity is linked to changes in mitochondrial DNA methylation

This study examined mitochondrial and nuclear-encoded mitochondrial DNA methylation in Indian patients with severe COVID-19 and found region-specific differential methylation linked to disease severity. Pathway analyses and protein assays implicated disrupted mitochondrial metabolism and dynamics, suggesting a role for mitochondrial epigenetic regulation in COVID-19 pathophysiology.

20 Jan 2026

Algae may help meet future protein demand without straining the planet

This narrative review evaluates clinical evidence on algae and algal proteins as sustainable, nutrient-dense food sources with high protein quality and bioactive compounds. Findings suggest potential benefits for muscle protein synthesis, cardiometabolic markers, immune modulation, and antioxidant status, while emphasizing heterogeneity, short-term data, and the need for longer clinical trials.

20 Jan 2026

Insulin anxiety and workplace barriers complicate gestational diabetes care

Insulin use in gestational diabetes presents challenges; education and support are key to overcoming fears and ensuring effective self-management for mothers.

20 Jan 2026

PFAS exposure increases gestational diabetes risk

A review of 130 studies links PFAS exposure to gestational diabetes, highlighting the need for further research on diabetes outcomes and environmental factors.

19 Jan 2026

Blood metabolites reveal who will develop type 2 diabetes years before diagnosis

This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention.

18 Jan 2026

Incretin-based diabetes drugs show potential protective effects against dementia

A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia.

15 Jan 2026