Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

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Type 1 Diabetes Cure

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Type 1 Diabetes Prevention

Latest Type 1 Diabetes News and Research

Clinical trial data shows preserved beta-cell function key to new paradigms in diabetes care

Critical Path Institute® (C-Path), through its Type 1 Diabetes Consortium, today reaffirmed its commitment to strengthening the regulatory-science and evidence infrastructure needed to enable the next phase of therapeutic innovation across multiple stages of type 1 diabetes (T1D).

16 Jun 2026

The importance of ketones from a clinical and medical perspective

In this interview, News-Medical talks to Marcin Pacek, senior director of medical and scientific affairs in Europe for Nova Biomedical, about the importance of ketones in a medical and clinical setting.

From Nova Biomedical 15 Jun 2026

Puerto Rico sees sharp rise in adolescent type 1 diabetes

The incidence of type 1 diabetes among teens in Puerto Rico more than doubled from 2009 to 2021 and remained elevated through 2024, with an average annual increase of 4.1 percent, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Type 2 diabetes elevates periodontitis risks regardless of glycemic control

Persons with diabetes have an increased risk of periodontitis (gum disease) and tooth loss. The risk of inflammation and bone loss at dental implants was also higher. These are the findings of a thesis at the University of Gothenburg.

9 Jun 2026

GLP-1 therapies linked to fewer complications in adults with both obesity and autoimmune disease

Among adults with both obesity and an autoimmune disease, those taking a glucagon-like peptide-receptor 1 agonist (GLP-1RA) medication had lower rates of emergency department visits and were less likely to experience serious cardiac events, such as stroke, pulmonary embolism or death when compared to similar adults who were not taking these medications, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

7 Jun 2026

Infections pose major but overlooked risks in people with diabetes

Infections should be considered a "health hazard" in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognized burden of illness, hospitalization and death.

7 Jun 2026

EULAR 2026 highlights rising comorbidity risks in rheumatic disease

People with rheumatic and musculoskeletal diseases (RMD) are at risk of a number of comorbidities, from cardiovascular diseases to cognitive impairment and fractures.

4 Jun 2026

New technique protects pancreatic islet transplants without immunosuppressive drugs

Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood sugar levels.

3 Jun 2026

Modified stem cell therapy reverses new-onset Type 1 diabetes in mice

A group of researchers at the Medical University of South Carolina (MUSC) has recently developed a new stem cell therapy with a remarkable ability to reverse new-onset Type 1 diabetes (T1D) in a mouse model of the disease.

2 Jun 2026

Complete 3D map of pancreas reveals surviving insulin cells

Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas.

26 May 2026

Immunoproteasome plays emerging role in diabetes and metabolic complications

A newly published review article highlights the emerging importance of the immunoproteasome in the development and progression of diabetes and its wide-ranging complications, offering fresh perspectives on future therapeutic strategies.

24 May 2026

Study supports routine childhood screening for type 1 diabetes

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care.

21 May 2026

New therapies could help type 1 diabetes care move beyond insulin alone

Disease-modifying therapies for type 1 diabetes are beginning to move care beyond insulin replacement by targeting immune dysregulation, beta-cell stress, and preservation of endogenous beta-cell function. Teplizumab marks a major clinical milestone, but the review emphasizes that durable metabolic remission will likely require earlier screening, better patient selection, and sequential or combination therapies.

18 May 2026

Hydrogel breakthrough offers significant advance in type 1 diabetes treatment

Researchers from the University of Geneva (UNIGE) and Geneva University Hospitals (HUG) have reached a significant advance in the fight against type 1 diabetes. Using an innovative hydrogel that supports insulin-producing cells once transplanted into the body, the team successfully regulated blood sugar levels in diabetic mice.

18 May 2026

Large human islet study reveals new insights into diabetes risk

Diabetes is the most common and serious chronic disease worldwide, characterized by insufficient insulin to maintain proper blood glucose levels.

12 May 2026

Insulin-dependent diabetes linked to sharply higher dementia risk

Individuals with diabetes are at an increased risk of developing dementia but those with insulin-requiring type 2 diabetes and type 1 diabetes have the greatest risk, according to research presented at the 28th European Congress of Endocrinology in Prague.

8 May 2026

Extensive data analysis confirms the safety of aluminum adjuvanted vaccines

Current evidence does not support direct (causal) associations between aluminium adjuvanted vaccines and serious or long-term health outcomes, including autism, diabetes, and asthma, finds a review of the latest data published by The BMJ today.

7 May 2026

AI-driven model predicts type 1 diabetes risk with greater accuracy

Researchers use machine learning and genetic analysis to uncover type 1 diabetes risk factors, improving prediction accuracy and identifying patient subtypes.

5 May 2026

T1GRS model enhances prediction of genetic risk for Type 1 diabetes

In people with Type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy.

30 Apr 2026

ISSCR urges NIH to continue support human embryonic stem cell research

The International Society for Stem Cell Research (ISSCR) has submitted a formal response to a Request for Information (RFI) issued by the National Institutes of Health (NIH) regarding its pause on new submissions to the NIH Human Embryonic Stem Cell (hESC) Registry and considerations to reduce reliance on hESCs in federally supported research.

25 Apr 2026