Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Cure

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Type 1 Diabetes Prevention

Type 1 Diabetes Treatment

Type 1 Diabetes Research

Latest Type 1 Diabetes News and Research

Stricter glucose control may affect quality of life in people living with diabetes

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that, in people living with diabetes (type 1 or 2) using data from continuous glucose monitoring (CGM) devices paired with daily quality-of-life ratings, days with more widely fluctuating glucose readings (while still within safe limits) are followed by days with a better quality life compared to days with more stricter control– suggesting the burden of that stricter control could be preventing those individuals with stricter control from enjoying various activities.

11 Sep 2026

New AI model forecasts glucose changes in type 1 diabetes patients

Diabetes is one of the most common chronic diseases, affecting around 66 million adults in Europe - a figure projected to rise to more than 72 million by 2050.

9 Sep 2026

COVID-19 linked to lower subsequent risk of type 1 diabetes

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that people who have had COVID-19 have a lower, rather than higher, risk of subsequent development of type 1 diabetes (T1D).

8 Sep 2026

People with diabetes may have another reason to protect their cardiovascular health

Better cardiovascular health, measured using Life’s Essential 8, was associated with a lower risk of mild cognitive impairment among people with diabetes after accounting for genetic susceptibility. Associations with dementia varied by genetic risk, while higher LE8 scores were also linked to greater gray matter volume and lower white matter hyperintensity volume.

30 Aug 2026

Type 1 diabetes cases projected to increase worldwide by 2049

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) estimates the number of people living with type 1 diabetes (T1D) worldwide will increase by 29% from 9.4 million in 2025 to 12.1 million in 2049.

28 Aug 2026

Type 2 diabetes incidence increases 10-fold among American youth

Type 2 diabetes has traditionally been a disease that has developed mostly in middle-aged and older adults.

24 Aug 2026

A childhood shaped by sugar rationing was linked to mental health more than 50 years later

UK Biobank researchers examined whether sugar rationing during pregnancy and the first two years of life was associated with adult sweet-food preferences, sugar intake, brain structure, anxiety, and depression.

23 Aug 2026

New genetic risk score uncovers hidden type 1 diabetes cases

Incorporating a genetic risk score into standard testing for a genetic form of diabetes which affects young people could identify hidden type 1 diabetes in around one in five patients with a negative genetic test.

19 Aug 2026

Gene editing fails to protect beta-cell transplants from rejection

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

19 Aug 2026

Online AI breastfeeding advice causes dangerous delays in infant care

For sleep-deprived nursing moms, artificial intelligence may feel like a lifeline.

12 Aug 2026

Localized biochemical halo of IL-10 suppresses immune rejection of pancreatic beta cells

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Australian-first twin study aims to to unlock new insights into immune health

An Australian-first study of twins will seek to find out why two genetically similar people respond differently to infections, diseases and treatments.

4 Aug 2026

Continuous glucose monitors show no proven benefits for healthy people

Continuous glucose monitors are becoming increasingly popular, including among people without diabetes.

4 Aug 2026

Researchers train AI to detect diabetes and assign four diagnostic labels

Researchers developed a two-stage machine learning framework that detected diabetes and classified records as prediabetes, type 1, type 2, or type 3c diabetes using two public datasets. XGBoost showed strong internal performance, but inconsistent model rankings, non-standard variables, and the absence of external clinical validation limit immediate use.

29 Jul 2026

Prototype smart ring tracks multiple sweat biomarkers

The CHARM smart ring enables continuous monitoring of biochemical markers in sweat, paving the way for advanced metabolic health tracking and diabetes support.

27 Jul 2026

New stem cell approach targets functional cure for diabetes

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.

11 Jul 2026

Trial supports glargine use in resource-limited Type 1 diabetes care

A trial led by University of Pittsburgh researchers and published today in The Lancet Diabetes & Endocrinology adds nuance to the question of whether older human insulins are as effective as insulin analogues in low-resource settings.

6 Jul 2026

BCG vaccine may remodel the human brain's immune environment

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine - which is delivered through the skin to prevent tuberculosis - may remodel the human brain's immune environment, offering a potential biological explanation for previously observed associations between BCG vaccination and lower Alzheimer's disease risk.

6 Jul 2026

Cannabidiol shows preclinical promise for anxiety, depression and cognition

A new meta-analysis suggests that CBD may improve emotional behavior and cognition in animal models, but researchers caution that its clinical benefits still need to be proven in humans.

1 Jul 2026

LEF1 and niche-derived factors regulate T cell stemness across chronic diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops.

1 Jul 2026