Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Type 1 Diabetes Research

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Treatment

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Type 1 Diabetes Cure

Type 1 Diabetes Prevention

Latest Type 1 Diabetes News and Research

Texture-based analysis of OCT images reveals early retinal changes in diabetes

Diabetic retinopathy (DR) is a leading cause of blindness among working-age adults, affecting more than 130 million people worldwide.

27 Nov 2025

Higher stent complication risks found in patients with diabetes

Patients with diabetes have an increased risk of complications after stent implantation, according to a study from Karolinska Institutet in Sweden published in Diabetes Care.

27 Nov 2025

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

Study overturns assumptions about PTPN22 risk gene’s role in interferon production

A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of Type 1 interferon, a workhorse of the immune system.

25 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

$New project aims to predict bone healing and reduce complications from fractures$

New project aims to predict bone healing and reduce complications from fractures

Every year, nearly 10 million Americans experience a broken bone. A quarter of patients with lower leg fractures face delayed healing, and one in 10 patients will develop a nonunion, a break that requires additional major surgery to heal.

24 Nov 2025

New clues in pancreas lymph nodes, spleen could help detect and prevent type 1 diabetes

Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have it, most of the body's insulin-producing cells are destroyed.

22 Nov 2025

Study finds people with type 1 diabetes have higher bladder cancer risk

People with type 1 diabetes (previously called juvenile diabetes) are 4.29 times more likely to develop bladder cancer, according to a systematic review and meta-analysis by researchers at the Keck School of Medicine of USC.

19 Nov 2025

New transplant approach resets the immune system to stop Type 1 diabetes

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

18 Nov 2025

Automated insulin delivery improves glucose control in pregnant women with Type 1 diabetes

An international study co-led by University of Calgary researchers has found new insulin delivery technology helps control glucose levels during pregnancy for those with Type 1 diabetes, which is crucial to the health of women and their newborns.

13 Nov 2025

Maternal type 1 diabetes may protect children from developing the disease

Findings suggest maternal T1D exposure leads to protective epigenetic alterations in children, influencing immune response and type 1 diabetes susceptibility.

10 Nov 2025

Scientists turn human stomach cells into insulin-producing beta cells

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide.

6 Nov 2025

Finerenone offers hope for kidney protection in patients with type 1 diabetes

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease.

6 Nov 2025

Maternal type 1 diabetes confers a protective effect in children through epigenetic programming

Children with a family history of type 1 diabetes (T1D) have an increased risk of developing the disease.

6 Nov 2025

Study shows benefits of telemedicine for people with type 1 diabetes

People with type 1 diabetes achieved significantly better long-term blood glucose when their levels were monitored by healthcare professionals in real time, via a sensor under the skin, and they received regular advice in their daily lives.

4 Nov 2025

Breakthrough could offer a new therapeutic option for stopping diabetes-induced complications

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

30 Oct 2025

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to help answer how type 1 diabetes manifests and develop potential therapeutics to reverse or prevent the disease.

29 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

Smarter insulin pump systems help stabilize glucose in young patients, study reveals

A Polish study comparing insulin pump technologies in children with type 1 diabetes found that advanced hybrid closed-loop systems achieved superior glycemic stability compared to predictive low glucose suspend systems. Despite technological advances, poor diet and low physical activity still undermine optimal metabolic control.

22 Oct 2025