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Researchers fabricate highly-sensitive SERS probes to detect the PD-L1 biomarker

Recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) have reported the fabrication of ultrasensitive biosensors based on Surface-enhanced Raman Spectroscopy (SERS) to detect the cancer metastasis related programmed death ligand (PD-L1) biomarker.

1 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

Researchers uncover a novel interplay between coral pathogen and other coral commensal bacteria

Coral is a complicated holobiont, harboring an array of life forms at different scales, including coral cells, zooxanthellae, and associated bacteria, archaea, and viruses.

1 Jul 2022

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The experts agree -; the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for.

1 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.

30 Jun 2022

New study investigates the epigenetic drift of time passing

A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, "Time makes histone H3 modifications drift in mouse liver."

30 Jun 2022

Crystal structure of a human endogenous reverse transcriptase revealed

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

30 Jun 2022

Rice lab’s microbial community profiling software effectively identifies bacterial species

Part of a gene is better than none when identifying a species of microbe. But for Rice University computer scientists, part was not nearly enough in their pursuit of a program to identify all the species in a microbiome.

30 Jun 2022

Researchers discover new family of sensing genes in enteric bacteria using AI

Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence.

30 Jun 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

Kyoto scientists reveal characteristic behaviors of erythropoietin-producing cells

A research team at Kyoto University has revealed characteristic behaviors of erythropoietin (Epo)-producing cells.

30 Jun 2022

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin.

30 Jun 2022

Study of condensates offers new hope for the treatment of neurodegenerative diseases

The Körber European Science Prize 2022, endowed with one million euros, is to be awarded to the British cell biologist Anthony Hyman.

30 Jun 2022

Identification of potent SARS-CoV-2 macrodomain inhibitors

A recent study posted to the bioRxiv* preprint server illustrated the optimization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 3 (NSP3) macrodomain (Mac) inhibitor based on structure.

30 Jun 2022

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

A research team from the LKS Faculty of Medicine, The University of Hong Kong discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications.

30 Jun 2022

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

Two levels underground, Chicago's Field Museum has a secret bunker. The sub-basement Collections Resource Center houses millions of biological specimens for scientists around the world to use in their research, including countless bottles and jars containing pickled fish, lizards, and snakes, arranged like a library.

30 Jun 2022

Life Science News

Researchers fabricate highly-sensitive SERS probes to detect the PD-L1 biomarker

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

Researchers uncover a novel interplay between coral pathogen and other coral commensal bacteria

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

Combining AI and Zebrafish to Accelerate Drug Discovery

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

New study investigates the epigenetic drift of time passing

Crystal structure of a human endogenous reverse transcriptase revealed

Rice lab’s microbial community profiling software effectively identifies bacterial species

Researchers discover new family of sensing genes in enteric bacteria using AI

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Kyoto scientists reveal characteristic behaviors of erythropoietin-producing cells

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Study of condensates offers new hope for the treatment of neurodegenerative diseases

Identification of potent SARS-CoV-2 macrodomain inhibitors

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

SARS-CoV-2 3CLpro also susceptible to mutations

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Online version of algorithm shows how biases in RNA sequences affect gene expression

Combining AI and Zebrafish to Accelerate Drug Discovery

Connecting Health and Social Care to Improve Community Health

Just like magic; automated solutions for NGS library preparation

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