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Key Alzheimer's protein actively protects neurons from nuclear damage

Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD).

17 Jun 2026

Autism study reveals shared brain cell changes during early development

Hundreds of genes have been linked to autism, yet the precise molecular and cellular mechanisms behind it remain largely unclear.

17 Jun 2026

Developing brain cells routinely repair severe DNA damage during migration

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex.

17 Jun 2026

New pico-calorimeter detects antibiotic resistance via direct heat traces

When living cells grow, divide, or respond to drugs, they give off tiny amounts of heat that offer information about what the cells are doing. But since these heat signals are so vanishingly small, they have been traditionally impossible to measure directly.

17 Jun 2026

Researchers eliminate embryonic senescent cells, triggering severe neurovascular flaws

Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized cells that allow essential nutrients to enter, yet repel dangerous toxins and pathogens that may be circulating in the bloodstream. Scientists have long known what these barriers do, but less about how they are built during development.

17 Jun 2026

Synthetic biology platform unmasks hidden bacterial targets of bacteriophages

An interdisciplinary team of Rice University researchers has uncovered previously unknown relationships between bacteriophages - viruses that infect bacteria - and their bacterial hosts, offering a powerful new tool for next-generation microbiome engineering.

17 Jun 2026

Purdue develops next-generation platform to accelerate cancer drug discovery

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to dramatically accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies.

16 Jun 2026

Machine learning identifies natural compound to treat lung disease

A new study published in Engineering has combined machine learning (ML) and experimental validation to identify dihydromyricetin (DHM), a natural flavonoid, as a potent inhibitor of the TGF-β/ALK5 signaling cascade with therapeutic potential for idiopathic pulmonary fibrosis (IPF).

16 Jun 2026

New single-protein analysis technique provides unprecedented information on scramblases

A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical roles in biology.

16 Jun 2026

Hormone cycles dictate how the brain absorbs neuroprotective drugs

Consider what we ask of a clinical trial. We gather people who differ in nearly every way that matters, we give them the same drug at the same dose, and then we average the result and call the average truth.

16 Jun 2026

Leica Biosystems launches AI-powered digital pathology solution in Europe, Middle East and Africa

With the Aperio GT Elite, Leica Biosystems advances digital pathology in EMEA, combining high-throughput scanning with innovative AI quality control features.

From Leica Biosystems 16 Jun 2026

Gut bacteria may help explain why fatigue appears before illness

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

16 Jun 2026

Prevention proves cheaper than treatment for Li-Fraumeni syndrome

Screening people with the rare, inherited cancer-causing condition Li-Fraumeni syndrome (LFS) brings both medical and economic benefits to patients and healthcare systems, according to research to be presented to the annual conference of the European Society of Human Genetics today (Tuesday).

15 Jun 2026

Family genetics study reveals clues to longer healthspan

Understanding why some people stay healthy without developing disease until late in life (have an increased healthspan), whereas others become infirm at a much younger age has important implications for the health of today's ageing population.

15 Jun 2026

Researchers urge caution over large-scale newborn genome screening

New research from large population studies provides invaluable evidence on genome screening of newborn babies to reduce risks from overdiagnosis.

15 Jun 2026

Study identifies genetic marker associated with severe IBD

In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker that is associated with more severe ulcerative colitis and Crohn's disease – the major forms of IBD.

15 Jun 2026

Tiny genetic change influences coronavirus spillover into humans

Most pandemics start when a pathogen spreads from animals to humans. It's a leading explanation for the COVID-19 pandemic: the SARS-CoV-2 virus, which causes COVID-19, is a cousin to coronaviruses that live in bats.

15 Jun 2026

Gut microbes control liver genes by flipping DNA switches

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

15 Jun 2026

Dual-target CAR T therapy triggers broad immune response in brain cancer

Dual-target CAR T cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes and longer overall survival.

15 Jun 2026

UVA joins SPARK GLOBAL initiative to accelerate the development of new medicines

The University of Virginia has joined the SPARK GLOBAL initiative to accelerate the development of new medicines and find solutions for the most urgent and complex healthcare challenges of our time.

15 Jun 2026