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TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

A Northwestern University research team has discovered how scalding heat and tissue injury activate an ancient "pain" receptor in simple animals. The findings could lead to new strategies for analgesic drug design for the treatment of humans.

17 Oct 2017

Genetic diversity plays major role in evolution of drug resistance

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that high genetic diversity can prime new mutations that cause drug resistance.

17 Oct 2017

Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces 17 Oct 2017

Columbia scientists receive grant from CZI to construct atlas of cells in human spinal cord

Scientists at Columbia's Zuckerman Institute today received a grant from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, to construct an atlas of gene activity of all cells in the human spinal cord.

17 Oct 2017

Father's diet before sex could contribute to changes in the offspring’s health, study reveals

A new study, conducted by the University of Cincinnati (UC) biology professors Michal Polak and Joshua Benoit, suggests that a father's nutrition could play a similar role to the mother’s nutrition in his offspring’s health. Researchers from the University of Sydney's Charles Perkins Centre and the University of Western Australia also collaborated on the study.

16 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Essen BioScience, Inc. A Sartorius Company 16 Oct 2017

Fluence Analytics launches new patented protein and polymer stability monitoring product

Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and formulation and development times.

16 Oct 2017

Avantor opens new life sciences research and applications laboratory in South Korea

Avantor, a global supplier of ultra-high-purity materials for customers across the life sciences and advanced technologies sectors, recently opened a new life sciences research and applications laboratory in the GwangGyo district, Suwon, South Korea.

16 Oct 2017

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Using advanced mass spectrometry technology, scientists from the Florida campus of The Scripps Research Institute have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.

13 Oct 2017

Study shows that endocrine disrupting chemicals alter sex ratio in Blanchard's cricket frogs

A study published recently in Environmental Toxicology and Chemistry found that Blanchard's cricket frogs are highly sensitive to atrazine.

13 Oct 2017

RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

Specific regions of silenced DNA help define cell's identity, study suggests

The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down the wrong developmental path during maturation.

13 Oct 2017

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.

13 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

New x-ray analysis methodology reveals structure of disordered protein

Scientists at The University of Notre Dame have shown that disordered proteins have a structure very close to what would be expected for a truly random structure using a novel X-ray scattering (SAXS) analysis methodology.

13 Oct 2017

Researchers use mixed realty viewer to visualize complex biological networks in 3D

They call it the "hairy ball." It's an unflattering name for two-dimensional representations of a complex biological network, a depiction of a system of linkages and connections so complex and dense that "it looks like a big mess," said Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute and director of the university's bioinformatics and computational biology program.

13 Oct 2017

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University of Notre Dame are one step closer to unraveling the mystery of how intrinsically disordered proteins work, according to new research published in Science

13 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

Whole genome sequencing could help better understand genetic abnormalities underlying autism

An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.

12 Oct 2017

Life Science News

TGen project to develop standard operating procedures for single-cell RNA sequencing

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

Genetic diversity plays major role in evolution of drug resistance

Using AFM to study cell mechanics and function

Columbia scientists receive grant from CZI to construct atlas of cells in human spinal cord

Father's diet before sex could contribute to changes in the offspring’s health, study reveals

Investigating new cancer therapy candidates with live-cell imaging

Fluence Analytics launches new patented protein and polymer stability monitoring product

Avantor opens new life sciences research and applications laboratory in South Korea

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Study shows that endocrine disrupting chemicals alter sex ratio in Blanchard's cricket frogs

RUDN University scientists synthesize new range of cytotoxic substances

Specific regions of silenced DNA help define cell's identity, study suggests

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Study helps understand basic mechanisms of mitochondrial DNA maintenance

New x-ray analysis methodology reveals structure of disordered protein

Researchers use mixed realty viewer to visualize complex biological networks in 3D

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

MIT researchers develop new technique to screen for genes that protect against diseases

Whole genome sequencing could help better understand genetic abnormalities underlying autism

Using AFM to study cell mechanics and function

Investigating new cancer therapy candidates with live-cell imaging

Freezing Point Osmometry in Life Science Applications

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