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Researchers discover new mutation hotspot in the human genome

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we study genetics and disease.

26 Nov 2025

Freezing cells for success: DMSO-free redefining the future of cryopreservation

Cryopreservation plays a crucial role in cell biology research, bioprocessing, and biomanufacturing. Traditionally, DMSO (dimethyl sulfoxide) has been the cryoprotectant of choice for preserving cells.

From NIPPON Genetics EUROPE GmbH 25 Nov 2025

Global data show why gut microbiomes in industrialized regions look increasingly alike

Researchers studying more than 1 000 adults across 12 countries found that industrialization is one of the strongest forces reshaping the human gut microbiome, reducing diversity and stability. Industrialized and urban populations also showed higher immune and gut stress markers, suggesting physiological consequences of these altered microbial communities.

25 Nov 2025

Long-term calorie restriction can slow cellular markers of brain aging

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage.

25 Nov 2025

How immune signals activate brain circuits to drive sickness-induced social withdrawal

MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection.

25 Nov 2025

Polyamines restore gut regeneration in aging mice

With aging, the intestine gradually loses its ability to regenerate after damage. An international research team involving the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena and the University of Turin has now found that polyamines, small molecules produced naturally in the body, can play a decisive role in this process.

25 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Genetic factors behind impulsive choices tied to metabolic and mental health

Researchers from University of California San Diego have identified 11 genetic regions linked to delay discounting - the tendency to prefer smaller, immediate rewards over larger, delayed ones - shedding new light on how impulsive decision-making relates to both mental and physical health.

24 Nov 2025

Study introduces cost-effective approach to analyze entire T-cell repertoire

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital.

24 Nov 2025

Scientists reverse aging in blood stem cells by restoring lysosome function

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

24 Nov 2025

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Arginine reduced amyloid beta aggregation in vitro and in both Drosophila and AppNL-G-F mouse models of Alzheimer’s disease, leading to fewer dense-core plaques and improved behavior. The study provides preclinical evidence that oral arginine may modulate amyloid pathology, although high dosing requirements and model limitations constrain human translation.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

New insights into ribosome collisions and stress response

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

24 Nov 2025

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

Wiley expands its spectral database with over 9.5 million high-quality spectra, enhancing compound identification for researchers in various scientific fields.

From John Wiley and Sons - Scientific Publishers 24 Nov 2025

Right-handed helical motion of malaria parasites revealed

With victims numbering in the millions, malaria is an infectious disease caused by the bite of a mosquito carrying the malaria parasite.

24 Nov 2025

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

22 Nov 2025

New sequencing method reveals how transposons move and shape the genome

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome.

22 Nov 2025

Research explores new solvent strategies to extend shelf life of injectable therapeutics

Sugar-based liquid solvents store crucial injection-based therapeutics such as insulin and vaccines.

22 Nov 2025

New signaling molecule drives development of tissue resident memory T cells

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

22 Nov 2025

Promising long-term vaccine for Crimean-Congo hemorrhagic fever developed

Crimean-Congo hemorrhagic fever (CCHF) is one of the world's most dangerous yet overlooked infectious diseases.

22 Nov 2025

Life Science News

Researchers discover new mutation hotspot in the human genome

Freezing cells for success: DMSO-free redefining the future of cryopreservation

Global data show why gut microbiomes in industrialized regions look increasingly alike

Long-term calorie restriction can slow cellular markers of brain aging

How immune signals activate brain circuits to drive sickness-induced social withdrawal

Polyamines restore gut regeneration in aging mice

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Genetic factors behind impulsive choices tied to metabolic and mental health

Study introduces cost-effective approach to analyze entire T-cell repertoire

Scientists reverse aging in blood stem cells by restoring lysosome function

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

New insights into ribosome collisions and stress response

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

Right-handed helical motion of malaria parasites revealed

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

New sequencing method reveals how transposons move and shape the genome

Research explores new solvent strategies to extend shelf life of injectable therapeutics

New signaling molecule drives development of tissue resident memory T cells

Promising long-term vaccine for Crimean-Congo hemorrhagic fever developed

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

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