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Research offers a phylogenetic and ontogenetic overview of the primitive streak

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of Virginia Health System, USA) offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications of embryonic stem cell-based models of early mammalian embryogenesis on the function of this structure.

4 Dec 2021

'Combination' adjuvant may boost the protective power of vaccines

Scientists at La Jolla Institute for Immunology and Massachusetts Institute of Technology, have found a possible way to improve the effectiveness of COVID-19 vaccines-;and any vaccine.

4 Dec 2021

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

SARS-CoV-2 causes the pandemic coronavirus disease COVID-19, that is more harmful for elderly people, who show more severe symptoms and are at higher risk of hospitalization and death.

3 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

Automate your sample pooling with INTEGRA’s efficient pipetting solutions

INTEGRA’s automated pipetting solutions are helping scientists meet the challenge of efficiently pooling potentially infectious samples prior to testing.

From INTEGRA Biosciences 3 Dec 2021

Modulating the composition of bacterial populations in the colon could enhance anti-tumor immunity

A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity.

3 Dec 2021

Penn researchers illuminate key molecular details of T-cell exhaustion process

Specially engineered immune cells called CAR T cells have proven themselves to be a powerful weapon against blood cancers, but against solid tumors they are much less effective, due in part to a process called T-cell exhaustion.

2 Dec 2021

Cannabis vapor exposure generationally affects sperm counts and motility in mice

An intense but short-term exposure to cannabis vapor lowered sperm counts and slowed sperm movement, or motility, not only in the directly exposed male mice but also in their sons.

2 Dec 2021

Study documents and visualizes hearing loss-associated genes in the inner ear

Researchers from Uppsala University have been able to document and visualise hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists.

2 Dec 2021

Immune cells play a much larger role in the onset of allergies than previously thought

A ground-breaking discovery from the Malaghan Institute has shone a light on immune cells in the skin, suggesting they play a much larger role in the onset of allergies than first thought.

2 Dec 2021

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital.

2 Dec 2021

Genetic variant found in Old Order Amish may confer protective effects against cardiovascular disease

Whole-exome sequencing and association analysis in nearly 7,000 Old Order Amish reveals a genetic variant that may confer protective effects against cardiovascular disease (CVD), researchers report.

2 Dec 2021

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Researchers investigate the antiviral activities of SSPS extracted from green seaweed Ulva sp. to demonstrate the anti-SARS-CoV-2 activity of ulvans.

2 Dec 2021

Researchers introduce new method for observing cell interactions

Researchers created a system that allows scientists to ‘log’ a cell’s reactions to external stimuli within the cell’s genetic material.

2 Dec 2021

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at population scale when combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes.

2 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Preventing SARS-CoV-2 transmission at large indoor events

A new trial showed that indoor live events are not associated with an increased risk of SARS-CoV-2 infection, provided preventive interventions are in place.

2 Dec 2021

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.

1 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Life Science News

Research offers a phylogenetic and ontogenetic overview of the primitive streak

'Combination' adjuvant may boost the protective power of vaccines

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

New nanoparticle adjuvant could help make vaccines more powerful

Automate your sample pooling with INTEGRA’s efficient pipetting solutions

Modulating the composition of bacterial populations in the colon could enhance anti-tumor immunity

Penn researchers illuminate key molecular details of T-cell exhaustion process

Cannabis vapor exposure generationally affects sperm counts and motility in mice

Study documents and visualizes hearing loss-associated genes in the inner ear

Immune cells play a much larger role in the onset of allergies than previously thought

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

Genetic variant found in Old Order Amish may confer protective effects against cardiovascular disease

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Researchers introduce new method for observing cell interactions

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

NEI researchers identify unique population of B cells that tamps down the immune system

Preventing SARS-CoV-2 transmission at large indoor events

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

Green tea shown to increase the defensive capabilities of cells

New genetic technology for gene expression analysis of cancer cells

Advancing our understanding of T cells to improve cancer therapies

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