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Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

23 Jul 2026

Scientists create programmable immune receptors for disease-resistant crops

Crop production faces threats from plant pathogens. Traditional disease-resistance breeding relies heavily on natural plant resistance genes that encode immune receptors adapted to particular pathogens.

23 Jul 2026

Targeting acid ceramidase could improve healthy aging and longevity

Our population is aging. The United Nations reports that by 2050, the number of people over the age of 85 on our planet is set to triple.

23 Jul 2026

Study reveals how DNA misfolding causes congenital heart disease

Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes for this disorder is having only one functional copy of the gene TBX5, instead of two healthy copies, inherited from parents.

23 Jul 2026

Researchers link genome folding to gene activity and brain tissue organization in Alzheimer's

Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington shed new light on Alzheimer's disease that could point to new directions for treatment.

23 Jul 2026

Study reveals dynamic remodeling of genome architecture during brain aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

23 Jul 2026

Mass-producible immune cells fight solid human tumors in mice

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

23 Jul 2026

Chemotherapy leaves early genomic fingerprints in childhood tumors

Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids).

23 Jul 2026

CRISPR-Cas orchestrates a layered defense network to fight bacterial viruses

All cellular life-from humans to bacteria-possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but not in the microbial world.

23 Jul 2026

New bacterial control strategy helps revive failing last-line antibiotics

Antimicrobial resistance is one of the world's most alarming public health challenges, because the multidrug-resistant (MDR) gram-negative bacteria increasingly render even last-line antibiotics ineffective, leading to substantially higher mortality rates.

23 Jul 2026

TriLink BioTechnologies® further strengthens global IP position with newly issued patent in China for CleanCap® capping technology

TriLink BioTechnologies, LLC (TriLink®), a Maravai LifeSciences company and global provider of life science reagents and services, has been granted a new patent from the China National Intellectual Property Administration (CNIPA), Patent number ZL 2025 11246578.X, covering methods of synthesizing RNA molecules.

From TriLink Biotechnologies 23 Jul 2026

New imaging platform tracks hundreds of neurons at unprecedented depths

The brain is a vast, densely interconnected network of neurons computing in parallel. Watching these computations unfold in real time could reveal how the brain processes sensation and guides behavior.

23 Jul 2026

AI platform uncovers promising target for chronic pain treatmen

Despite the widespread availability of analgesics, pain management remains one of the most significant and pervasive challenges in modern medicine, with more than 20% of the global population suffering from chronic pain, especially chronic neuropathic pain characterized by central sensitization.

22 Jul 2026

Study reveals bacterial strategy behind antibiotic tolerance and persistence

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.

22 Jul 2026

DNA enhancer hubs control cancer genes in prostate tumors

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

22 Jul 2026

SuperAgers retain exceptional memory through mechanisms beyond genetics

Many people assume that some memory decline is an inevitable consequence of getting older. But a select group of older adults, known as SuperAgers, reach their 80s and 90s while retaining memory performance as good as or better than people in their 50s and 60s.

22 Jul 2026

Urbanization reshapes gut microbiomes across diverse South Asian communities

Urbanization is one of the most consequential demographic shifts of the 21st century. As communities move from traditional or rural to urbanized ways of life, changes in diet, lifestyle, and environmental exposures can influence many aspects of human biology and health.

22 Jul 2026

Genetic background shapes cancer development despite identical risk factors

Why do cancers develop differently in different people-even when they are exposed to the same risk factors? An international research group, including the German Cancer Research Center (DKFZ), has now demonstrated in mice that an organism's genetic makeup significantly influences the course of cancer development.

22 Jul 2026

Excess tubulin disrupts tissue organization and cell survival

A UNIGE study shows that even a slight overproduction of tubulin, a protein essential for cell structure, is enough to disrupt tissue organization, highlighting the need for tight regulation of protein levels.

22 Jul 2026

Curcumin shows the best balance against cancer, study shows

Curcumin, berberine, and other plant-derived compounds have long attracted scientific interest because of their anti-inflammatory and anticancer properties.

22 Jul 2026