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High-resolution study maps molecular differences across six human cortical regions

A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in gene activity between male and female brains. This may help explain why some psychiatric and neurological disorders appear to affect the biological sexes differently, researchers report.

17 Apr 2026

Researchers use light-activated drugs to map the brain's internal painkillers

Placebo effects, in which patients experience relief without therapeutic treatment, increasingly have been considered as potentially powerful clinical treatments for ailments such as depression and pain. Yet the neurological mechanisms underlying such processes are not fully understood. Now, a multi-institutional team led by the University of California San Diego's Matthew Banghart, an associate professor in the School of Biological Sciences, has pinpointed the brain circuitry responsible for placebo pain relief.

17 Apr 2026

New imager separates UV and infrared light to find cancerous nodes

Researchers have developed a compact camera that captures ultraviolet, near-infrared and visible images using a single chip. Inspired by the multiwavelength vision capability of the mantis shrimp, the camera could help surgeons identify lymph nodes connected to a tumor and assess whether cancer has spread to them, making cancer surgery safer and less invasive.

17 Apr 2026

Researchers use tiny glass capillaries to sample living cancer cell parts

A new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first

17 Apr 2026

Why AI is becoming a powerful tool in cancer drug discovery

This Perspective reviews how AI is moving drug discovery from long, costly experimental pipelines toward earlier clinical translation, with an AI-designed TNIK inhibitor trial serving as an important proof-of-feasibility reference point. It argues that precision oncology could benefit from AI-driven integration of multi-omics, federated learning, and adaptive trial design, but only if validation, fairness, interpretability, and regulatory alignment improve.

16 Apr 2026

Scientists discover how the immune system signals the brain to avoid germs

Researchers from the University of Bonn and University Hospital Bonn uncover vital mechanism for survival

16 Apr 2026

Understanding cell messaging provides a blueprint for targeting inaccessible tumors

Researchers at University College Dublin have discovered a previously unknown "courier system" that cells use to deliver coherent biological messages between each other, opening new possibilities for medicine and biotechnology.

16 Apr 2026

New research reveals how bacteria "selflessly" share DNA through GTAs

Research has shed important new light on the enemies-turned-allies that allow bacteria to exchange genes, including those linked to antimicrobial resistance (AMR).

16 Apr 2026

Researchers discover how stress signals weaken the aging immune system

As we age, our ability to maintain healthy blood and a strong immune system gradually declines, largely because hematopoietic stem cells (HSCs), the cells responsible for producing all blood cell types, begin to lose their effectiveness. Normally, HSCs can both self-renew and generate a balanced mix of blood cells, but over time they produce fewer new cells, favor certain cells such as myeloid cells over lymphoid cells, and struggle to support a robust immune response.

16 Apr 2026

Waters debuts industry-first extended-range MALS detector for UHPLC/UPLC, powering rapid characterization of large molecules

Waters Corporation today announced the launch of the Waters omniDAWN™ Multi-Angle Light Scattering (MALS) Photometer, part of the Wyatt Technology Portfolio.

From Waters Corporation 16 Apr 2026

Migraine genes linked to worse headaches after concussion in children

A University of Calgary-led study has found evidence that children with genes predisposing to migraine might have an increased risk of having more headaches after a concussion, which are known to be linked to prolonged symptoms up to six-months after the injury.

15 Apr 2026

New RNA sequencing method improves rare disease diagnosis

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare diseases.

15 Apr 2026

Study explains failure of cellular cleanup in neurodegenerative diseases

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled.

15 Apr 2026

Mitochondrial activity keeps dendritic cells ready to fight disease

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular metabolism to gene regulation and T-cell activation.

15 Apr 2026

New model advances study of cardiac fibroblasts and fibrosis

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to cardiac damage.

15 Apr 2026

New research reveals how parasites break out of host cells

Parasites are a major global health problem, underlying many human diseases worldwide. For example, Plasmodium falciparum, the parasite responsible for malaria, plays a well-established; however, its complex life cycle is not yet fully understood.

15 Apr 2026

Parents' genes shape children's mental health beyond inherited DNA

What if some of the risk of anxiety and depression in children is not only about the genes they inherit, but also about their parents' genetic dispositions and how these influence the home environment?

15 Apr 2026

New CRISPR tool selectively cuts tumor DNA while sparing healthy cells

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells.

15 Apr 2026

Atelerix forms strategic partnership with JH Health Ltd to expand non-cryogenic cell preservation capabilities in the Middle East

Atelerix, a biotech company revolutionising cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced it has established a strategic partnership with JH Health Ltd, a Saudi Arabian company focused on medical and health-related technology.

From Atelerix Ltd 15 Apr 2026

African health expert: genomic sequencing enables near real-time pathogen detection

Advanced genomic sequencing techniques, like mNGS, are essential for accurate pathogen detection, crucial for effective outbreak response and patient care.

From BGI Genomics 15 Apr 2026