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New molecule offers a more targeted and potent immunotherapy

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the "do not attack" signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects.

18 Sep 2025

New genetic test can help predict how people will respond to weight-loss medications

Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.

17 Sep 2025

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to infertility and changes expression of hundreds of other important genes.

17 Sep 2025

Dipeptides reveal clues to the origin of life’s instructions

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

Enhanced Genomics extends Series A funding to USD $19 million to drive development of therapeutics pipeline

Enhanced Genomics ('Enhanced'), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced it has completed a financing round, extending its total Series A funding to $19 million.

17 Sep 2025

New findings show lymph nodes educate T cells to combat disease

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against chronic infection and cancer.

17 Sep 2025

INTEGRA exceeds environmental targets, pioneering sustainable science

INTEGRA Biosciences is part of the Science Based Targets initiative (SBTi), a scheme that provides independent assessment and approval of companies' carbon-reduction targets according to 3 scopes.

17 Sep 2025

CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments.

16 Sep 2025

AI breakthrough offers a new way to predict and visualize disease processes

To solve a problem, we have to see it clearly. Whether it's an infection by a novel virus or memory-stealing plaques forming in the brains of Alzheimer's patients, visualizing disease processes in the body is the first step toward alleviating human suffering. It's also often the most difficult and costly.

16 Sep 2025

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

16 Sep 2025

New imaging technique enhances live-cell visualization in standard lab setups

Optical diffraction tomography (ODT) has long been recognized for its potential in non-invasive, label-free imaging of live biological cells. However, a major challenge arises when ODT is applied to standard multi-well cell culture plates, a common tool use under realistic laboratory conditions for biological studies.

16 Sep 2025

AlphaFold3 predicts bitter taste receptor structures with greater accuracy

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses.

16 Sep 2025

FUJIFILM Biosciences introduces BalanCD HEK293 perfusion a medium to enable gene therapy production

FUJIFILM Biosciences, a global leader in the innovation and manufacture of cell culture solutions for the Life Science market, today announced the commercial launch of BalanCD HEK293 Perfusion A.

15 Sep 2025

Normal cells working together can sense far beyond their environment

The story of the princess and the pea evokes an image of a highly sensitive royal young woman so refined, she can sense a pea under a stack of mattresses.

13 Sep 2025

DeepInMiniscope enables high-resolution 3D imaging of brain activity in mice

Researchers at the University of California, Davis, have created a miniaturized microscope for real-time, high-resolution, non-invasive imaging of brain activity in mice.

13 Sep 2025

Rice University team develops tool to track protein aggregation hot spots

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

13 Sep 2025

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

13 Sep 2025

Scientists uncover how amino acids stabilize proteins in solution

For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways. And for decades, scientists have known that this works – but not why.

13 Sep 2025

Unlocking hidden soil microbes for new antibiotics

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

13 Sep 2025