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Multicolor fluorescent tagging enables real-time visualization of RNA in living cells

An innovative three-color method for capturing images of mRNA inside live mammalian cells has been developed by UMass Amherst chemists.

17 Dec 2025

Researchers uncover how a gene influences cell size across various cell types

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis behind cell size has largely been a mystery.

17 Dec 2025

Early life gut microbiome crucial for immune system development

Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even when infants need antibiotic treatment.

17 Dec 2025

Sino Biological wins 2025 Scientist.com’s Supplier Recognition Award

Sino Biological, Inc., a global leader in biological reagents and CRO services, recently announced that it has been honored with the “2025 Supplier Performance Recognition Award” by Scientist.com, the market-leading digital platform for outsourced R&D procurements.

From Sino Biological Inc. 16 Dec 2025

Urine-based microRNA clock predicts biological aging without a blood test

Researchers developed and validated a non-invasive urinary microRNA aging clock using extracellular vesicle miRNAs from more than 6,000 adults. The model predicts age with about 4 to 5 years error and links accelerated aging signals to type 2 diabetes.

16 Dec 2025

AI tool reveals hidden proteins in Earth’s vital microalgae

Scientists at NYU Abu Dhabi have developed a powerful new artificial intelligence tool called LA⁴SR that can rapidly identify previously overlooked proteins in microalgae - tiny organisms that produce much of the Earth's oxygen and support entire aquatic ecosystems.

16 Dec 2025

Opposing protein forces fine tune mRNA stability in human cells

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

16 Dec 2025

Neuron structure variations impact sensory information processing in mice

Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.

16 Dec 2025

Novel cryo-EM findings could revolutionize T cell immunotherapy design

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full understanding of how they actually work has eluded researchers.

16 Dec 2025

Scientists discover rapid synapse adaptation in neuronal communication

Every movement you make and every memory you form depends on precise communication between neurons. When that communication is disrupted, the brain must rapidly rebalance its internal signaling to keep circuits functioning properly.

16 Dec 2025

Metagenomics reveals overlooked viral risks in treated water

Viruses are everywhere in wastewater treatment plants, quietly interacting with bacteria as sewage is cleaned and reused.

15 Dec 2025

Australian scientists uncover key genetic drivers behind long COVID

Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.

15 Dec 2025

How brain cells manage long distance genetic instructions

Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated groups.

15 Dec 2025

Novel AI tool not only identifies genetic mutations but also predicts the type of disease

Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only identifies disease-causing genetic mutations but also predicts the type of disease those mutations may trigger.

15 Dec 2025

Two compounds sourced from cannabis show promising anti-cancer effects

In the future, scientists could use drugs made from cannabis to fight ovarian cancer. A team of scientists testing the effects of two chemical compounds sourced from cannabis on ovarian cancer cells have found that both show promising anti-cancer effects.

15 Dec 2025

Atelerix enters agreement with Cherry Biotech to integrate non-cryogenic transport solutions with advanced organoid models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced it has entered a partnership with Cherry Biotech, a French company specializing in organ-on-chip and organoid technologies for biomedical research.

15 Dec 2025

Researchers develop powerful tools for microbiome research advancement

The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the planet's ecosystems. Yet even with modern DNA sequencing, figuring out what these microbes are and how they are related to one another remains extremely difficult.

13 Dec 2025

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

13 Dec 2025

External signals control oncolytic bacteria for precise cancer therapy delivery

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.

13 Dec 2025