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New insights on replication-stress sensitivity in breast cancer cells

Oncotarget published "Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity" which reported that these authors recently documented that gain-of-function mutant p53 R273H in triple negative breast cancer cells interacts with replicating DNA and PARP1.

28 Jul 2021

Oncotarget data reveals retinoic acid as fundamental regulator of cell cycle and differentiation

Oncotarget published "Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells" which reported that retinoic acid is a fundamental regulator of cell cycle and cell differentiation.

28 Jul 2021

T cells are not critical for recovery of primates from acute COVID-19 infections, study reveals

New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.

27 Jul 2021

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

27 Jul 2021

Research provides insights into how the hippocampus contributes to memory storage in the cortex

A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored in the visual cortex, the ability to recognize a sequence of sights critically depends on guidance from the hippocampus, a deeper structure strongly associated with memory but shrouded in mystery about exactly how.

27 Jul 2021

Analysis of DNA tags could advance the understanding and treatment of many cancers

Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer Center now believe that studying tags, or modifications to this type of DNA, may lead to a better understanding of how to assess, and possibly modulate, treatment approaches for cancer and other diseases.

27 Jul 2021

Simple method to assess the risk of vascular inflammation for diabetes patients

A team of international scientists from Nanyang Technological University, Singapore (NTU Singapore), Tan Tock Seng Hospital (TTSH) in Singapore, and the Massachusetts Institute of Technology (MIT) has developed a simple method of extracting tiny biological particles from a person's blood and use them as biomarkers to assess the health of their blood vessels.

27 Jul 2021

PerkinElmer to Acquire Antibody and Reagent Leader BioLegend

PerkinElmer, Inc. today announced it has entered into an agreement to acquire BioLegend, a leading, global provider of life science antibodies and reagents.

From PerkinElmer 27 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Breakthrough treatment could improve the immune system's ability to destroy cancer cells

New research has identified potential treatment that could improve the human immune system's ability to search out and destroy cancer cells within the body.

26 Jul 2021

Newly identified ultra-rare inherited genetic variants may confer significant autism risk

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum.

26 Jul 2021

Porvair Increase Porous Plastics Manufacturing Capacity

Porvair Sciences reports on the installation of new automated precision die-cutting equipment that has enabled a five-fold increase in its production capacity for porous plastic components.

From Porvair Sciences Limited 26 Jul 2021

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

Metrion today announced the appointment of Nick Foster as Chief Commercial Officer and Head of Global Business Development.

26 Jul 2021

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus.

26 Jul 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Researchers investigate brain responses to aesthetically appealing natural landscapes

How does a view of nature gain its gloss of beauty? We know that the sight of beautiful landscapes engages the brain's reward systems.

23 Jul 2021

Bacteria use a 'sense of touch' mechanism to navigate on surfaces

Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as "twitching". Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ignore which sensory signals coordinate the microbes' movements.

23 Jul 2021

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

From the thrill of hearing an ice cream truck approaching to the spikes of pleasure while sipping a fine wine, the neurological messenger known as dopamine has been popularly described as the brain's "feel good" chemical related to reward and pleasure.

23 Jul 2021

Study brings scientists one step closer to solving the mystery of aging

The human body is essentially made up of trillions of living cells. It ages as its cells age, which happens when those cells eventually stop replicating and dividing.

23 Jul 2021

Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Life Science News

New insights on replication-stress sensitivity in breast cancer cells

Oncotarget data reveals retinoic acid as fundamental regulator of cell cycle and differentiation

T cells are not critical for recovery of primates from acute COVID-19 infections, study reveals

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Research provides insights into how the hippocampus contributes to memory storage in the cortex

Analysis of DNA tags could advance the understanding and treatment of many cancers

Simple method to assess the risk of vascular inflammation for diabetes patients

PerkinElmer to Acquire Antibody and Reagent Leader BioLegend

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Breakthrough treatment could improve the immune system's ability to destroy cancer cells

Newly identified ultra-rare inherited genetic variants may confer significant autism risk

Porvair Increase Porous Plastics Manufacturing Capacity

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

Novel microfluidic device used to manipulate major whey protein

Researchers investigate brain responses to aesthetically appealing natural landscapes

Bacteria use a 'sense of touch' mechanism to navigate on surfaces

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

Study brings scientists one step closer to solving the mystery of aging

Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs

Increasing your risk of IBD through processed food

World Brain Day 2021: An interview with Professor Alan Thompson

Preventing lethal blood clots

Latest Life Science News