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Redefining health science in the age of exposomics

We live in the age of -omics. We have genomics to study complete sets of DNA. We have proteomics focused on all the proteins within our cells.

13 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025

How solvents influence drug delivery efficiency in MOFs

Even the best products won't meet expectations if they are packed poorly - packaging matters. The same goes for drug delivery.

13 Jun 2025

Study uncovers molecular mechanism behind 'ticking' of the circadian clock in cyanobacteria

Researchers from the Institute for Molecular Science (IMS)/SOKENDAI and Kyushu University have uncovered the molecular mechanism that drives the "ticking" of the circadian clock in cyanobacteria.

13 Jun 2025

AI and film animation tools lead to breakthrough in coronavirus drug discovery

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases, to epidemic and even pandemic outbreaks, as we experienced with the COVID-19 pandemic.

13 Jun 2025

Researchers reverse muscle stem cell aging with Prostaglandin E2

The population across developed countries is getting older and the associated frailty and debilitation are becoming major health problems.

13 Jun 2025

Lab-grown mini intestines reveal how Shigella infects human gut

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut.

12 Jun 2025

New CRISPR tool enables precise chemical modification of RNA in living cells

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects.

12 Jun 2025

Autophagy boosts precision in gene editing

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations.

12 Jun 2025

Bitter 'supertaster gene' tied to bipolar disorder and poor kidney function

People who carry a bitter 'supertaster gene' have been linked to various health conditions including bipolar disorder and poor kidney function, University of Queensland researchers have found.

12 Jun 2025

New open access tool could accelerate drug discovery

Scientists at Northwestern University have developed the largest open-access resource of its kind to help researchers shave off months of early-stage drug development time by allowing them to better understand diseases and find potential treatments.

12 Jun 2025

Blocking a single enzyme rewires limb regrowth in axolotls

Researchers uncovered how CYP26B1-mediated retinoic acid (RA) breakdown determines segment identity during axolotl limb regeneration. Disrupting RA degradation reprograms blastema cells, revealing the molecular controls of precise limb regrowth.

11 Jun 2025

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Scientists discover hundreds of new metabolites linked to the human microbiome

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us.

10 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025