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The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Analysis of how wood compounds affect the quality of alcoholic beverages

A new study in the journal Molecules aimed to analyze the effect of using wood for the maturation of different alcoholic beverages.

15 Jan 2023

Researchers unveil new methods for DNA mosaic recognition

As humans, we each have trillions of cells. And each cell has a nucleus with individual genetic information –DNA – that can mutate to create an abnormality.

13 Jan 2023

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Chemists from the University of Groningen have found a simple way to produce previously inaccessible chiral Z-alkenes, molecules that offer a significant synthetic short-cut for the production of bioactive molecules.

13 Jan 2023

Machine learning tool can enhance the inference of complex cell identities

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Altering a cellular process can lead stem cells to die or regenerate, study finds

A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead stem cells-;cells from which other cells in the body develop-;to die or regenerate.

13 Jan 2023

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Scientists from The Australian National University and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

13 Jan 2023

New breakthrough in understanding the genetic causes of "malformations of cortical development"

Epilepsy is present in 4% of the population, and is among the most common brain disorders in children. Modern medicine can prevent most seizure recurrences, but approximately 20% of patients do not respond to treatment.

12 Jan 2023

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

A new CRISPR-Cas9 approach that targets a detrimental signaling pathway in the heart confers protection from ischemia/reperfusion injury, according to a study in mice.

12 Jan 2023

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases -; signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism.

12 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Rats and mice have been the backbone of biomedical research for decades -; including research to understand cancer and pioneer new treatments.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

LJI scientists uncover how OGT enzyme keeps cells healthy

Researchers at La Jolla Institute for Immunology have at last uncovered how an enzyme called O-GlcNAc transferase (OGT) keeps cells healthy.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

Life Science News

The loss of epigenetic information accelerates the aging process

Analysis of how wood compounds affect the quality of alcoholic beverages

Researchers unveil new methods for DNA mosaic recognition

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Machine learning tools help unravel why human accelerated regions evolved so quickly

Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Machine learning tool can enhance the inference of complex cell identities

Valuable tool reveals the connections between gut microbes and the brain

Altering a cellular process can lead stem cells to die or regenerate, study finds

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

New breakthrough in understanding the genetic causes of "malformations of cortical development"

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

New technique could overcome the delivery hurdles faced by promising mRNA therapies

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

LJI scientists uncover how OGT enzyme keeps cells healthy

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

Unique mass spectrometry-based approach to study specific changes in DNA after replication

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Using the power of light to transform analytical workflows in the life sciences

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