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Current and Future Applications of Optogenetics

Optogenetics is the science of using light to control the behavior of cells. It is one of the most rapidly evolving fields of applied research. Optogenetic techniques enable the control of electrically excitable cells such as muscle or nerve cells.

Current and Future Applications of Optogenetics

Chagas: A Neglected Disease in the United States

Chagas disease is a parasitic infection caused by the protozoan Trypanosoma cruzi. It is most often transmitted by nocturnal, blood-sucking insects called kissing bugs. When the kissing bug feeds, it defecates, and the sleeping victim unconsciously scratches the bite scene and introduces the infected feces into their blood stream.

Chagas: A Neglected Disease in the United States

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Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Relieving Symptoms of Cystic Fibrosis with Exercise

We know that exercise is beneficial in helping someone to maintain their lung function, stay strong and active and maintain a good quality of life. We also know that exercise can complement ‘airway clearance techniques’ – breathing exercises prescribed by physiotherapists to help clear the lungs of mucus.

Relieving Symptoms of Cystic Fibrosis with Exercise

Biological applications of AFM

Samuel Lesko has more than 20 years experiences in running AFM over variety of applications. After obtaining a PhD at Burgundy university on colloidal force measurement in cement, he started his career at Veeco Instruments as French Applications Scientists before to continue on supporting Bio Applications AFM European wide. He is since 2007 Applications manager for Europe, Middle East and Africa. Recently, his position expanded to Latin America.

Biological applications of AFM