Alzheimer's & Dementia

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

Alzheimer’s Disease | Definition, Causes, Diagnosis & Treatment

Alzheimer’s Disease (AD) is the most common form of dementia worldwide (60-70% of all dementia cases) and is a progressive neurodegenerative disorder.

What is Dementia?

Differences Between Alzheimer's and Dementia

Alzheimer's Disease Causes

Alzheimer's Disease Symptoms

Alzheimer's Disease Diagnosis

Alzheimer's Disease Treatments

Alzheimer's Disease Questions

Alzheimer's Disease Epidemiology

Pollution and Alzheimer's

Is Alzheimer's Disease Transmissible?

Diet and Alzheimer's Disease

See more featured articles »

Types of Alzheimer's Disease

Stem Cell Therapy for Alzheimer's

Alzheimer's and Veganism

Biomarkers for Alzheimer's Disease

Alzheimer's Disease Prevention

Inflammation and Alzheimer's Disease

Alzheimer's Disease and Sleep Disruption

Does Herpesvirus Cause Alzheimer's?

Stress and Alzheimer's Disease

Alzheimer's Disease and the Microbiome

Amyloid Cascade Hypothesis

What Causes Dementia?

Dementia Diagnosis

Dementia Prevention

Dementia Symptoms

Dementia Treatment

Dementia with Lewy Bodies

Bright Light Therapy and Dementia

Aromatherapy for Dementia

Coconut Oil and Dementia

What is Mixed Dementia?

Transcutaneous Electrical Nerve Stimulation for Dementia

Childhood Dementia Causes

Mixed Dementia Prevention and Treatment

Mixed Dementia Symptoms and Diagnosis

Childhood Dementia Signs and Symptoms

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Antidepressants and Dementia: Is There a Link?

Does Depression and Anxiety Increase the Risk of Dementia?

Migraines and Dementia

What are Amyloid Plaques?

Latest Alzheimer's & Dementia News and Research

Study aims to more accurately define methods for measuring delirium severity

In a study published in the journal Dementia and Geriatric Cognitive Disorder, researchers reported on their effort to improve and validate tools used to assess the severity of a condition called delirium, an acute confusional state often experienced by older hospitalized patients.

8 Jul 2020

Dual sensory impairment in older adults linked to higher risk for dementia

Older adults with both hearing and visual impairments—or dual sensory impairment—had a significantly higher risk for dementia in a recent study published in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

8 Jul 2020

COVID cuts a lethal path through San Quentin’s death row

The old men live in cramped spaces and breathe the same ventilated air. Many are frail, laboring with heart disease, liver and prostate cancer, tuberculosis, dementia. And now, with the coronavirus advancing through their ranks, they are falling one after the next.

8 Jul 2020

Scientists receive grant to study cerebrovascular changes during healthy and Alzheimer's aging

Scientists often focus on abnormal accumulations of proteins called plaques in the brain in efforts to find a treatment for Alzheimer's disease. But the effects of these plaques have not been clear.

7 Jul 2020

Desk-based jobs associated with lower risk of poor cognition

People who work in jobs that require less physical activity - typically office and desk-based jobs - are at a lower risk of subsequent poor cognition than those whose work is more physically active, suggests new research from the University of Cambridge.

7 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Study shows how non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation

Research from University of South Carolina associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences, Arnold School of Public Health, and led by Ayan Mondal, a postdoctoral researcher from the same lab, has revealed the cause behind the previously established link between non-alcoholic fatty liver disease (i.e., NAFLD, recently reclassified as metabolic associated fatty liver disease or MAFLD) and neurological problems.

6 Jul 2020

New treatment approach for Alzheimer's disease

A new study published in The Journal of Physiology has shown that misfolded protein build-up in the gut could contribute to the development of Alzheimer's-like symptoms in mice.

3 Jul 2020

Brain imaging can predict cognitive decline in Alzheimer’s disease

Researchers at Karolinska Institutet in Sweden have imaged tau protein in the brains of living patients with Alzheimer's disease.

2 Jul 2020

Study identifies a promising way to delay the onset of Alzheimer's disease

Currently we are facing a dementia epidemic, estimations showing that by 2050 approximately 131 million people will be affected. Every 7 seconds a patient is diagnosed worldwide.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

NIH announces $75 million in funding to improve genomic risk assessments for diverse populations

The National Institutes of Health has announced the provision of $75 million in funding over five years for the Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network, which establish protocols and methodologies for improved genomic risk assessments for diverse populations and to integrate their use in clinical care.

1 Jul 2020

More than one-third of excess deaths in pandemic's early months linked to other causes

Since COVID-19's spread to the United States earlier this year, death rates in the U.S. have risen significantly. But deaths attributed to COVID-19 only account for about two-thirds of the increase in March and April, according to a study published Wednesday in the Journal of the American Medical Association.

1 Jul 2020

CHOP researchers receive multi-million dollar grant to study disease risk in African Americans

The National Institutes of Health announced today that researchers from Children's Hospital of Philadelphia are among the recipients of a multi-million dollar grant that focuses on the use of genomics to improve risk assessment for diverse populations and integrate the findings into clinical care.

1 Jul 2020

Common asthma drug may offer potential as treatment for Alzheimer's disease

A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer's disease.

1 Jul 2020

Study sheds light on selective neuronal vulnerability in Alzheimer’s disease

When Alzheimer's disease strikes, the entire brain doesn't crumble at once. Instead the mind unravels like grim clockwork, beginning with the telltale degradation of a group of brain cells in the entorhinal cortex.

1 Jul 2020

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

New study will help primary care nurses better care for dementia patients

McLean Hospital's Brent P. Forester, MD, MSc, is heading a new study of a training model to help primary care nurses better care for patients with dementia.

30 Jun 2020

Researchers track brain receptor as it transmits or inhibits neural signals

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain development and function, the receptor converts chemical messages between cells into electrical signals within a neuron.

30 Jun 2020