Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will gather leading ALS researchers and clinicians to discuss the latest research and perspectives on the disease.

23 Oct 2025

Media images convey a fear-inducing and negative picture of dementia

Conducted at the University of Eastern Finland, a new study shows that images portraying dementia in Finnish newspapers often paint a clichéd and negative picture.

23 Oct 2025

Impaired movement of cerebrospinal fluid predicts dementia risk later in life

Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Strong grip strength lowers risk of organ dysfunction in obesity

People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.

21 Oct 2025

New noninvasive device measures brain blood flow using laser speckle technology

Measuring blood flow in the brain is critical for responding to a range of neurological problems, including stroke, traumatic brain injury (TBI) and vascular dementia.

21 Oct 2025

Women with isolated REM sleep behavior disorder show lesser brain atrophy than men

A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson's disease show significantly less brain atrophy—decreased cortical thickness in the brain—than men, despite similar clinical severity.

21 Oct 2025

Earlier menopause and reduced cardiac function may negatively affect brain health

Women face a higher risk of developing both cardiovascular disease and Alzheimer's disease than men. Cardiovascular disease is linked to an increased likelihood of Alzheimer's disease, especially among women.

21 Oct 2025

Study offers a nuanced understanding of how bedroom ventilation affects sleep health

Good sleep is key to good health, overall well-being, and optimal cognitive function. Disturbed sleep or lack of sleep can lead to various health issues such as cardiovascular diseases, cancer, and other morbidity, including Alzheimer's disease and obesity.

21 Oct 2025

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Women are significantly more likely than men to develop Alzheimer's disease. Earlier age at menopause is associated with a greater risk for late-life cognitive decline and Alzheimer's disease.

21 Oct 2025

Transdermal hormone therapy offers potential reduction in anxiety and depression

Hormone therapy–oral and transdermal–remains the most effective treatment for such bothersome menopause symptoms as hot flashes and is generally considered safe for most patients. A new study shows that risk profiles are different based on how the hormones are administered.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

Social and environmental inequality linked to risk of Alzheimer’s

The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare.

20 Oct 2025

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

17 Oct 2025

New 3D human brain tissue platform integrates all major brain cell types into a single culture

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture.

17 Oct 2025

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule essential for the development and function of the nervous system, new research suggests.

17 Oct 2025

Advanced MRI technique reveals early markers of hereditary frontotemporal dementia

An international study led by researchers at Karolinska Institutet in Sweden demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques.

16 Oct 2025

New NIA grant advances tools for dementia caregiving

More than 7 million Americans live with Alzheimer's disease and related dementias (ADRD), supported by 12 million unpaid family caregivers whose contributions are valued at $413 billion annually.

15 Oct 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

Media images convey a fear-inducing and negative picture of dementia

Impaired movement of cerebrospinal fluid predicts dementia risk later in life

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

People with multiple sclerosis found to have dysbiotic oral microbiome

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Strong grip strength lowers risk of organ dysfunction in obesity

New noninvasive device measures brain blood flow using laser speckle technology

Women with isolated REM sleep behavior disorder show lesser brain atrophy than men

Earlier menopause and reduced cardiac function may negatively affect brain health

Study offers a nuanced understanding of how bedroom ventilation affects sleep health

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Transdermal hormone therapy offers potential reduction in anxiety and depression

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Social and environmental inequality linked to risk of Alzheimer’s

Study reveals how a microglial mutation increases risk for Alzheimer's disease

New 3D human brain tissue platform integrates all major brain cell types into a single culture

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Advanced MRI technique reveals early markers of hereditary frontotemporal dementia

New NIA grant advances tools for dementia caregiving

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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