Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Combined physical frailty and depression may sharply raise dementia risk

Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these 2 factors alone contributing around 17% of the overall risk, suggest the findings of a large international study, published in the open access journal General Psychiatry.

16 Dec 2025

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

University of Virginia School of Medicine researchers have uncovered how and why traumatic brain injury (TBI) increases the risk for Alzheimer's disease, and their work suggests a potential way to prevent that increased risk.

16 Dec 2025

Study identifies molecular drivers of cerebral small vessel disease

A new study identifies molecular factors that promote small vessel disease - and an active drug that can restore impaired vascular functions.

16 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

New research highlights the importance of social engagement for cognitive health

New research from the University of St Andrews has discovered a direct causal effect between social isolation and a faster decline in later- life cognitive function. Pathological cognitive decline is most often driven by Alzheimer's and related dementias.

16 Dec 2025

Blood-based biomarkers and the new landscape of Alzheimer’s research

For much of the past century, Alzheimer's disease has been one of medicine's most daunting frontiers—biologically complex, devastating in impact, and difficult to diagnose early.

From Quanterix 15 Dec 2025

New framework tracks response to anti-amyloid therapies in Alzheimer's

In the last few years, progress has been made in the fight against Alzheimer's disease with a class of therapies called anti-amyloid antibodies (anti-Aβ).

15 Dec 2025

New study defines rapidly progressive dementia

A new multicenter study led by Mayo Clinic researchers has established a practical, evidence-based definition for rapidly progressive dementia (RPD), a rare but devastating form of cognitive decline that develops over months instead of years.

15 Dec 2025

Six midlife depressive symptoms linked to dementia decades later

Six particular depressive symptoms when experienced in midlife predict dementia risk more than two decades later, finds a new study led by University College London (UCL) researchers.

15 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

FAU researchers create deep learning model that detects and evaluates Alzheimer's, FTD

Dementia is a group of disorders that gradually impair memory, thinking and daily functioning. Alzheimer's disease (AD), the most common form of dementia, affects about 7.2 million Americans aged 65 and older in 2025.

15 Dec 2025

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

Researchers have developed a new tool, FibrilPaint combined with the FibrilRuler test, that allows scientists to directly measure the length of toxic Tau amyloid fibrils in tiny fluid samples, from the earliest aggregation stages to mature fibrils and even at very low concentrations.

11 Dec 2025

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name - cell migration inducing and hyaluronan-binding protein, or CEMIP - is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer's disease.

11 Dec 2025

Cuffless blood pressure devices show great promise as alternatives to traditional arm-cuff monitors

Cuffless devices to measure blood pressure, such as smartwatches, rings, patches and fingertip monitors, show great promise as alternatives to traditional arm-cuff monitors, however, they are not yet proven accurate enough to diagnose high blood pressure or guide treatment decisions, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

11 Dec 2025

Driving simulator exposes early Parkinson’s impairments that routine tests fail to detect

A high-fidelity driving simulator detected subtle visuospatial, attentional, and reaction time impairments in people with mild to moderate Parkinson’s disease, even when standard cognitive tests appeared normal. The study shows that simulator-based assessments can uncover real-world driving difficulties linked to disease severity that traditional screening tools often miss.

10 Dec 2025

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

10 Dec 2025

Analysis of Alzheimer's disease and related dementias uncovers disparities in Maryland's rural communities

A new statewide spatial analysis of Alzheimer's disease and related dementias (ADRD) has uncovered significant disparities in Maryland's rural communities, offering a striking example of how healthcare accessibility is shaping health outcomes across the United States.

10 Dec 2025

New arts and wellbeing program supports the social needs of families affected by dementia

A new arts and wellbeing program co-developed by the University of South Australia, Flinders University and the University of Adelaide shows that supporting the social needs of people living with dementia and their carers can help families rediscover connection, confidence and a sense of community.

9 Dec 2025

How delays and bankruptcy let a nursing home chain avoid paying settlements for injuries and deaths

Nancy Hunt arrived at an emergency room from a Genesis HealthCare nursing home in Pennsylvania in such dreadful shape, including maggots infesting her gangrened foot, that the hospital called an elder abuse hotline and then the police, her son alleged in a lawsuit.

9 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Combined physical frailty and depression may sharply raise dementia risk

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

Study identifies molecular drivers of cerebral small vessel disease

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

New research highlights the importance of social engagement for cognitive health

Blood-based biomarkers and the new landscape of Alzheimer’s research

New framework tracks response to anti-amyloid therapies in Alzheimer's

New study defines rapidly progressive dementia

Six midlife depressive symptoms linked to dementia decades later

Single-pill combination medications may simplify treatment for adults with high blood pressure

FAU researchers create deep learning model that detects and evaluates Alzheimer's, FTD

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Cuffless blood pressure devices show great promise as alternatives to traditional arm-cuff monitors

Driving simulator exposes early Parkinson’s impairments that routine tests fail to detect

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

Analysis of Alzheimer's disease and related dementias uncovers disparities in Maryland's rural communities

New arts and wellbeing program supports the social needs of families affected by dementia

How delays and bankruptcy let a nursing home chain avoid paying settlements for injuries and deaths

Online reference library provides a more accurate picture of drug exposure

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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