Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk.

25 Aug 2025

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study finds.

22 Aug 2025

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025

Midkine found to prevent Alzheimer’s-related protein assemblies

Scientists at St. Jude Children's Research Hospital demonstrated for the first time that the protein midkine plays a preventative role against Alzheimer's disease.

21 Aug 2025

Computational approach provides insight into neural progenitor cells and their role in brain disorders

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

21 Aug 2025

How older people are reaping brain benefits from new tech

It started with a high school typing course. Wanda Woods enrolled because her father advised that typing proficiency would lead to jobs. Sure enough, the federal Environmental Protection Agency hired her as an after-school worker while she was still a junior.

21 Aug 2025

Scientists explore hookworm proteins as potential treatment for inflammation

It's been a long-accepted reality that with age comes increased inflammation – so widely accepted it's been dubbed "inflammaging."

21 Aug 2025

Metabolic syndrome linked to higher risk of Parkinson's disease

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of Parkinson's disease, according to a study published on August 20, 2025, in Neurology, the medical journal of the American Academy of Neurology.

20 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

New genetic study reveals why people age differently

It's a fact of life: Some people age better than others. Some ease into their 90s with mind and body intact, while others battle diabetes, Alzheimer's or mobility issues decades earlier.

20 Aug 2025

Women with Alzheimer's show reduced levels of healthy unsaturated fats

Omega fatty acids could protect against Alzheimer's disease in women, new research has found.

20 Aug 2025

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

The American Geriatrics Society (AGS) has released a landmark update to its list of alternatives to medications listed in the 2023 AGS Beers Criteria - the most widely adopted guidelines to help clinicians identify potentially inappropriate medications for older adults.

18 Aug 2025

RNA quality control protein PELOTA found to slow aging and extend lifespan

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.

18 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Brain organoids reveal early changes in familial Alzheimer’s disease

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20 individuals aged 65 and above. In addition to environmental and lifestyle factors, genetic mutations can predispose an individual to AD and some rare forms of inherited "familial" AD (fAD) are caused by known genetic mutations, with these affected individuals developing AD with high probability and at relatively young age.

14 Aug 2025

Helping others regularly slows cognitive decline in older adults

In the latest evidence that meaningful social connections bolster health, a team from The University of Texas at Austin and University of Massachusetts Boston has found that regular time spent helping outside the home significantly slows cognitive decline in middle-age and older adults.

13 Aug 2025

New discovery in spinal cord neurons offers hope for breathing recovery

Today about 300,000 people nationally living with a spinal cord injury and with respiratory complications being the most common cause of illness and death, according to the Christopher & Dana Reeve Foundation.

13 Aug 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Research shows how lysosomes respond to stress

Midkine found to prevent Alzheimer’s-related protein assemblies

Computational approach provides insight into neural progenitor cells and their role in brain disorders

How older people are reaping brain benefits from new tech

Scientists explore hookworm proteins as potential treatment for inflammation

Metabolic syndrome linked to higher risk of Parkinson's disease

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

Rethinking chronic disease management in older adults

New genetic study reveals why people age differently

Women with Alzheimer's show reduced levels of healthy unsaturated fats

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

RNA quality control protein PELOTA found to slow aging and extend lifespan

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Dementia-like protein clumping found in early pancreatic cancer cells

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Brain organoids reveal early changes in familial Alzheimer’s disease

Helping others regularly slows cognitive decline in older adults

New discovery in spinal cord neurons offers hope for breathing recovery

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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