Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Brain cells amplify important signals to guide focus and navigation

Nerve cells in the brain are constantly bombarded with information from different senses simultaneously. How can the brain prioritize what is most important?

6 Mar 2026

Single dose of CAR-astrocyte therapy halves amyloid levels in mice brains

The new generation of Alzheimer's disease drugs - the first proven to change the course of the disease - typically extend independent living for patients by 10 months.

6 Mar 2026

New report shows primary care readiness for digital cognitive assessment tools

A new Gerontological Society of America (GSA) report summarizes survey findings on the readiness of the primary care workforce to adopt digital cognitive assessments (DCAs) for use in the diagnostic process for cognitive impairment and dementia.

6 Mar 2026

New study shows the brain reactivates memories without reaching conscious thought

Researchers have used brain imaging to show how memories can be reactivated in the brain without them reaching conscious awareness, showing that these memories persist even when we think they have been forgotten.

6 Mar 2026

Seniors defy stereotypes of decline through positive mindsets

Aging in later life is often portrayed as a steady slide toward physical and cognitive decline. But a new study by scientists at Yale University suggests an alternate narrative - that older individuals can and do improve over time and their mindset toward aging plays a major part in their success.

6 Mar 2026

Drug combination shows greater weight loss while preserving muscle mass

A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, such as skeletal muscle and connective tissue.

5 Mar 2026

Machine learning detects early brain changes linked to Alzheimer's disease

Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy.

5 Mar 2026

New microscope captures 3D blood flow and oxygenation at single-cell resolution

The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural tissue like electrical wires.

5 Mar 2026

Study reveals a disease-relevant role for tanycytes in neurodegeneration

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

5 Mar 2026

Neural circuit mechanisms explain how chronic sleep loss disrupts social memory

Social memory—the ability to recognize familiar individuals and distinguish them from strangers—is fundamental to social cognition.

5 Mar 2026

Protein linked to Parkinson's may drive faster Alzheimer's disease progression in women

Alzheimer's-related brain changes progressed up to 20 times faster in women who also had abnormal levels of a Parkinson's-related protein, according to a Mayo Clinic study published in JAMA Network Open.

4 Mar 2026

Study links gut microbiome health directly to ovarian aging processes

A new study details how fecal transplants from older female mice significantly improve ovarian function and fertility in young mice. The surprising results reveal a direct link between the microbiome (the collection of all bacteria and other microbes present) of the gut and ovarian health and function.

3 Mar 2026

Can brain training prevent dementia? Long-term trial shows speed training with boosters makes a difference

A 20-year follow-up of older adults in the ACTIVE randomized trial linked to Medicare claims found that speed of processing cognitive training with booster sessions was associated with a significantly lower risk of diagnosed Alzheimer’s disease and related dementias. Memory and reasoning training did not show comparable long-term reductions in dementia risk.

2 Mar 2026

Low‑dose oral lithium may help slow the decline of verbal memory, trial suggests

Lithium-a decades-old treatment for bipolar disorder-may hold potential neuroprotective benefits beyond mood stabilization.

2 Mar 2026

Investigating microglia’s role in Alzheimer’s pathology

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.

1 Mar 2026

Machine learning predicts who will decline faster in Alzheimer’s disease using routine clinic data

Researchers developed and validated ElasticNet machine learning models that predict 12-month MMSE and BADL outcomes in Alzheimer’s disease and mild cognitive impairment using routinely collected clinical data. The cognitive model demonstrated external validation in ADNI, showing that individualized progression forecasting is feasible without biomarkers or neuroimaging.

1 Mar 2026

Misdiagnosed Parkinson's patient regains life after NPH treatment

At age 66, Richard "Dick" Nash first suspected something might be wrong when he participated in a Dallas walk for juvenile diabetes in honor of his granddaughter.

26 Feb 2026

Antibiotics alter gut bacteria to aid brain healing

What if healing the brain after traumatic injury starts in the gut?

26 Feb 2026

Imaging technique can objectively identify a recently recognized type of dementia, LATE

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

26 Feb 2026

Lymphovenous anastomosis may be an effective treatment for Alzheimer's disease

A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease (AD), according to a special article in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

26 Feb 2026