Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Smell-based test taken at home could predict cognitive impairment in older adults

When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham developed olfactory tests-in which participants sniff odor labels that have been placed on a card-to assess people's ability to discriminate, identify and remember odors.

24 Mar 2025

What do Blue Zone diets have in common? Polyphenols that may slow aging

Scientists reviewed how polyphenol-rich diets in Blue Zones may help people live longer, healthier lives by targeting biological hallmarks of aging. They call for more research to measure polyphenol intake and test its effects on human longevity.

24 Mar 2025

Skipping exercise? Just sitting less may still improve your metabolic health

Older adults who limit their sedentary time have lower metabolic syndrome risk, regardless of how active they are or how healthy they eat. Even light movement can support better metabolic health when replacing prolonged sitting.

24 Mar 2025

Advanced imaging technique reveals how nuclear pores regulate molecular movement

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus.

22 Mar 2025

Research reveals how dendrites connect memories in the brain

If you've ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites.

22 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Deep sleep may protect against neurodegeneration

Sleep disturbances may accelerate neurodegeneration, but whether they cause or result from disease remains unclear. Improving sleep quality could help protect against cognitive decline and brain aging.

20 Mar 2025

Daytime sleepiness may double dementia risk in elderly women

For women in their 80s, experiencing increasing sleepiness during the day over a five-year period is associated with double the risk of developing dementia during that time, according to a study published on March 19, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

20 Mar 2025

Experimental drug shows promise in reducing risk of Alzheimer's-related dementia

An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), which is based at Washington University School of Medicine in St. Louis.

19 Mar 2025

Older immigrants and immigrants with dementia face interconnected barriers to social and medical services in Finland

A recent study by the University of Eastern Finland shows that barriers to accessing social and medical services among older immigrants and immigrants with dementia in Finland are interconnected.

19 Mar 2025

Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

The findings come from the most comprehensive computer model of brain metabolism to date, which incorporates more than 16,800 biochemical interactions between proteins and chemicals across brain cells, supporting cells, and the blood.

19 Mar 2025

Understanding the role of CD2AP in Alzheimer's disease

A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide.

19 Mar 2025

New discovery unravels mystery behind overactive immune responses

Autoimmune diseases, which are estimated to affect more than 15 million people in the U.S., occur when the body responds to immune-system false alarms, and infection-fighting first responders are sent out to attack threats that aren't there.

18 Mar 2025

Alzheimer's-modifying drug lecanemab's effectiveness may vary between genders

Since becoming only the second Alzheimer's-modifying drug to gain American Federal Drug Administration approval in 2023, sales of lecanemab, known by its brand name Leqembi, have risen steadily, reaching $87-million USD in the last quarter of 2024.

18 Mar 2025

Study: Witnessing trauma triggers unique brain changes

For years, post-traumatic stress disorder (PTSD) has been studied primarily in people who experience trauma firsthand.

18 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

Better heart health slows brain aging and lowers dementia risk, study finds

A JAMA Network Open study finds that better cardiovascular health (CVH) in older adults is linked to lower levels of neurodegenerative biomarkers, particularly neurofilament light chain (NfL). These benefits are consistent across races and especially impactful for individuals carrying Alzheimer's-related genetic risks.

16 Mar 2025

COVID-19 cut millions of healthy life years across Europe, study shows

The COVID-19 pandemic caused a staggering 16.8 million person-years of life lost across 18 European countries, with nearly 60% of those years expected to be lived without disability. The research highlights both direct COVID-19 deaths and indirect impacts like healthcare disruptions and rising non-COVID mortality.

16 Mar 2025

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Smell-based test taken at home could predict cognitive impairment in older adults

What do Blue Zone diets have in common? Polyphenols that may slow aging

Skipping exercise? Just sitting less may still improve your metabolic health

Advanced imaging technique reveals how nuclear pores regulate molecular movement

Research reveals how dendrites connect memories in the brain

Targeting brain’s waste removal system may help combat cognitive decline

Deep sleep may protect against neurodegeneration

Daytime sleepiness may double dementia risk in elderly women

Experimental drug shows promise in reducing risk of Alzheimer's-related dementia

Older immigrants and immigrants with dementia face interconnected barriers to social and medical services in Finland

Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

Understanding the role of CD2AP in Alzheimer's disease

New discovery unravels mystery behind overactive immune responses

Alzheimer's-modifying drug lecanemab's effectiveness may vary between genders

Study: Witnessing trauma triggers unique brain changes

Probiotic drink kefir shows promise in preventing Alzheimer’s

IL-12 targeting could open pathways for new Alzheimer's treatments

Better heart health slows brain aging and lowers dementia risk, study finds

COVID-19 cut millions of healthy life years across Europe, study shows

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

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Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

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