Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

New genetic study reveals why people age differently

It's a fact of life: Some people age better than others. Some ease into their 90s with mind and body intact, while others battle diabetes, Alzheimer's or mobility issues decades earlier.

20 Aug 2025

Women with Alzheimer's show reduced levels of healthy unsaturated fats

Omega fatty acids could protect against Alzheimer's disease in women, new research has found.

20 Aug 2025

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

The American Geriatrics Society (AGS) has released a landmark update to its list of alternatives to medications listed in the 2023 AGS Beers Criteria - the most widely adopted guidelines to help clinicians identify potentially inappropriate medications for older adults.

18 Aug 2025

RNA quality control protein PELOTA found to slow aging and extend lifespan

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.

18 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Brain organoids reveal early changes in familial Alzheimer’s disease

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20 individuals aged 65 and above. In addition to environmental and lifestyle factors, genetic mutations can predispose an individual to AD and some rare forms of inherited "familial" AD (fAD) are caused by known genetic mutations, with these affected individuals developing AD with high probability and at relatively young age.

14 Aug 2025

Helping others regularly slows cognitive decline in older adults

In the latest evidence that meaningful social connections bolster health, a team from The University of Texas at Austin and University of Massachusetts Boston has found that regular time spent helping outside the home significantly slows cognitive decline in middle-age and older adults.

13 Aug 2025

New discovery in spinal cord neurons offers hope for breathing recovery

Today about 300,000 people nationally living with a spinal cord injury and with respiratory complications being the most common cause of illness and death, according to the Christopher & Dana Reeve Foundation.

13 Aug 2025

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

Late nights, alcohol, and smoking on weekends may be doing more than disrupting your Monday mornings, they could be triggering a newly identified sleep health concern known as 'social apnea', warn researchers from Flinders University.

13 Aug 2025

New computer model provides detailed look at mouse brain vasculature

Healthy brain function relies on a steady supply of blood. Disruptions in blood flow are linked to major neurological conditions like stroke, Alzheimer's disease (AD), and traumatic brain injuries. But understanding how the brain fine-tunes this flow – especially across its smallest blood vessels – remains a challenge.

13 Aug 2025

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

According to research by the University of California, Irvine, women with Down syndrome have more advanced signs of Alzheimer's disease than men do at the average age of diagnosis, which is the same for both sexes.

12 Aug 2025

Cats with dementia show brain changes similar to Alzheimer’s in humans

Cats with dementia have brain changes similar to those of people with Alzheimer's disease, offering a valuable model for studying the condition in humans, a study says.

12 Aug 2025

Study establishes a causal link between mitochondrial dysfunction and neurodegenerative diseases

Mitochondria, the tiny organelles without which our bodies would be deprived of energy, are gradually revealing their mysteries.

11 Aug 2025

New insights into how keto diet can restore cognitive function following status epilepticus

Epilepsy affects over 70 million people worldwide, and a significant portion of patients suffer from drug-resistant epilepsy (DRE), where standard medications fail.

11 Aug 2025

Brain aging may be slower and more layered than previously thought

The human brain ages less than thought and in layers – at least in the area of the cerebral cortex responsible for the sense of touch.

11 Aug 2025

Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

Researchers at Northwestern University’s SuperAging Program reveal how some people over 80 retain memory performance like those decades younger, linking it to unique brain structures, reduced pathology, and lower inflammation. Their 25-year study highlights genetic, cellular, and social traits that may protect cognitive function.

10 Aug 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

Rethinking chronic disease management in older adults

New genetic study reveals why people age differently

Women with Alzheimer's show reduced levels of healthy unsaturated fats

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

RNA quality control protein PELOTA found to slow aging and extend lifespan

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Dementia-like protein clumping found in early pancreatic cancer cells

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Brain organoids reveal early changes in familial Alzheimer’s disease

Helping others regularly slows cognitive decline in older adults

New discovery in spinal cord neurons offers hope for breathing recovery

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

New computer model provides detailed look at mouse brain vasculature

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

Cats with dementia show brain changes similar to Alzheimer’s in humans

Study establishes a causal link between mitochondrial dysfunction and neurodegenerative diseases

New insights into how keto diet can restore cognitive function following status epilepticus

Brain aging may be slower and more layered than previously thought

Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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