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Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

In a new Northwestern Medicine study, scientists have developed a more precise genetic risk score to determine whether a person is likely to develop arrhythmia, an irregular heartbeat that can lead to serious conditions such as atrial fibrillation (AFib) or sudden cardiac death.

11 Nov 2025

New insights into how endoplasmic reticulum and lysosomes coordinate protein production

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.

11 Nov 2025

Shared genetic roots connect neurological and psychiatric disorders

In a groundbreaking study, researchers from the Centre for Precision Psychiatry at the University of Oslo and Oslo University Hospital have discovered extensive genetic links between neurological disorders like migraine, stroke and epilepsy, and psychiatric illnesses such as schizophrenia and depression.

11 Nov 2025

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

The DNBSEQ-T7 sequencing platform and 110K Human Genome Program are transforming South Africa's genomic landscape, promoting local expertise and health equity.

From MGI 11 Nov 2025

Preclinical study reveals dampened neuronal activity in alcohol-exposed mice

A psychedelic found in mushrooms is emerging as a potential treatment for alcohol use disorders. This possibility is due to a compound the body converts the psychedelic into called psilocin, but psilocin's mechanisms remain unclear.

11 Nov 2025

Study uncovers new mechanism for chromosome congression during mitosis

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division. The study demonstrates that two motor proteins, KIF18A and CENP-E, act cooperatively to ensure proper chromosome congression. Remarkably, simultaneous inhibition of these proteins selectively kills cancer cells, suggesting a promising therapeutic avenue.

10 Nov 2025

Micro-RNA in sperm proves vital for human embryogenesis

The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University, Sweden, shows that certain molecules that come with the sperm, so-called micro-RNA, contribute to the development of the embryo several days after conception. The findings, published in the journal Nature Communications, may in the long term contribute to better diagnosis and treatment of involuntary childlessness.

10 Nov 2025

Blood protein pattern linked to increased risk of hereditary atherosclerosis

A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is shown in a new study from Karolinska Institutet, examining close relatives of people who had suffered a heart attack at a young age.

10 Nov 2025

Studies uncover two novel, critical strategies for bacterial surface movement

New studies from Arizona State University reveal surprising ways bacteria can move without their flagella - the slender, whip-like propellers that usually drive them forward.

8 Nov 2025

Condensate-based strategy protects synthetic gene circuits across cell generations

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing the synthetic gene circuits to lose their new functions.

7 Nov 2025

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

7 Nov 2025

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection.

7 Nov 2025

Scientists uncover mechanism driving efficient protein deacetylation by Sir2 enzyme

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation cycle of the Sir2 enzyme, reveal researchers from Science Tokyo.

7 Nov 2025

Genomic mapping of resistance mutations in A. baumannii

The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections.

7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein, an integral step in the virus cycle.

7 Nov 2025

Life Science News

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

New insights into how endoplasmic reticulum and lysosomes coordinate protein production

Shared genetic roots connect neurological and psychiatric disorders

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

Preclinical study reveals dampened neuronal activity in alcohol-exposed mice

Study uncovers new mechanism for chromosome congression during mitosis

Micro-RNA in sperm proves vital for human embryogenesis

Blood protein pattern linked to increased risk of hereditary atherosclerosis

Studies uncover two novel, critical strategies for bacterial surface movement

Condensate-based strategy protects synthetic gene circuits across cell generations

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Scientists uncover mechanism driving efficient protein deacetylation by Sir2 enzyme

Genomic mapping of resistance mutations in A. baumannii

Comprehensive kinase atlas reveals new insights into cell signaling and disease

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

Researchers refine tools to map DNA’s 3D structure inside cells

Five-year project seeks new weapons against drug-resistant bacteria

Scientists turn human stomach cells into insulin-producing beta cells

Scientists map gut microbiota associated with coronary artery disease

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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