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Single-cell proteomic analysis uncovers hidden layers of blood cell formation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

21 Aug 2025

Yale researchers uncover new RNA editing tools for safer genetic surgery

The ability to correct disease-causing genetic mistakes using genome editors holds great promise in medicine, but it is not without risk.

21 Aug 2025

Physical forces play key role in shaping developing organs

A new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.

21 Aug 2025

Using light to control tissue folding in developing embryos

The complex 3D shapes of brains, lungs, eyes, hands, and other vital bodily structures emerge from the way in which flat 2D sheets of cells fold during embryonic development.

21 Aug 2025

Computational approach provides insight into neural progenitor cells and their role in brain disorders

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

21 Aug 2025

New genome-wide CRISPR screening tool boosts natural killer cells to fight cancer

Natural killer (NK) cells became markedly better at killing cancer cells after scientists removed key gene targets identified through a new genome-wide CRISPR screening tool, according to new research from The University of Texas MD Anderson Cancer Center.

21 Aug 2025

Nanodroplet array revolutionizes search for new drugs

Until now, the early phase of drug discovery for the development of new therapeutics has been both cost- and time-intensive.

21 Aug 2025

AI predicts designer drug structures for improved detection

How does one identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement. The chemical structure variations that help these compounds avoid detection also make them unpredictable in the body - a quality that poses serious health consequences.

21 Aug 2025

UCSF researchers uncover how breast cancer steals energy from fat cells

UCSF scientists caught cancer cells in the act of breaking into fat cells and releasing their fat. The energy heist seems to be critical for the growth of deadly breast cancer.

20 Aug 2025

Biology-aware machine learning enables efficient cell culture media optimization

Cell culture is a foundational technology widely used across fields such as pharmaceutical production, regenerative medicine, food science, and materials engineering.

20 Aug 2025

Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025

Cancer cells break down nerve covers causing immune exhaustion and therapy resistance

Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading to immune exhaustion and eventual resistance to immunotherapy, according to new research from The University of Texas MD Anderson Cancer Center.

20 Aug 2025