Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

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Latest Type 2 Diabetes News and Research

Tirzepatide lowers heart attack and cardiovascular event risk in adults with type 2 diabetes

In a US cohort of 52,971 adults with type 2 diabetes and established atherosclerotic cardiovascular disease, tirzepatide initiation was associated with a lower one-year risk of major adverse cardiovascular events than sitagliptin. The benefit was driven mainly by lower myocardial infarction and all-cause mortality hazards, although the authors cautioned that mortality findings may be influenced by residual confounding.

10 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

7 Aug 2026

Swiss flagship project harnesses AI and sensors for diabetes prevention

Type 2 diabetes generates high healthcare costs in Switzerland and causes significant suffering for those affected.

6 Aug 2026

New research highlights hidden metabolic risks in non-obese HIV patients

A new UC San Francisco study helps explain why people with HIV remain at elevated risk for type 2 diabetes despite effective suppression of the virus with modern medications.

6 Aug 2026

GLP-1 drug tirzepatide associated with lower risk of major cardiovascular events

Adding the GLP-1 receptor agonist drug tirzepatide (marketed as Mounjaro) to standard care for patients with type 2 diabetes and heart disease is associated with a lower risk of a major cardiovascular event, such as a heart attack or stroke, finds a study published by The BMJ today.

5 Aug 2026

Type 2 diabetes linked to more severe menopause symptoms

The type of menopause symptoms, as well as their severity, can differ greatly among women. A number of earlier studies have suggested various reasons for those differences.

5 Aug 2026

$GLP-1 therapy may help reduce fracture risk among adults with type 2 diabetes$

GLP-1 therapy may help reduce fracture risk among adults with type 2 diabetes

New research by UCLA Health found GLP-1 medications may reduce the risk of serious fractures for adults with type 2 diabetes.

4 Aug 2026

Exercise helps protect Hispanic adults from late life cognitive decline

Previous studies have examined the associations between adherence to LS7 and cognitive outcomes, with findings suggesting that higher LS7 scores are associated with better cognitive performance, reduced dementia risk and improved brain health.

4 Aug 2026

Researchers suggest a potential therapeutic strategy for muscle loss associated with obesity

Obesity has been linked to skeletal muscle loss and deterioration. While M2 macrophages may play a role in regulating muscle function, the underlying mechanisms remain poorly understood.

4 Aug 2026

Continuous glucose monitors show no proven benefits for healthy people

Continuous glucose monitors are becoming increasingly popular, including among people without diabetes.

4 Aug 2026

Study links lower vitamin D to mood and cognitive health in adults over 85 with diabetes

Researchers studying 188 adults aged 85 years or older with type 2 diabetes found the lowest serum 25(OH)D concentrations among those with both depressive symptoms and mild cognitive impairment. Lower levels remained associated with having both conditions after adjustment for selected factors, but the cross-sectional study cannot establish causation or a benefit from supplementation.

3 Aug 2026

Gestational diabetes cases surge across England, raising health concerns

One in eight mothers in England is now diagnosed with gestational diabetes, with diagnoses rising by 60 per cent in just five years, according to a major study.

3 Aug 2026

Ten-million-person study links semaglutide to lower COVID-19 mortality

Researchers analyzing claims from more than 10.1 million commercial insurance and Medicare Advantage enrollees found that semaglutide use was associated with a 49% lower adjusted hazard of COVID-19-related death. The observational findings corroborate earlier SELECT trial results but do not establish causation, making further prospective research essential.

30 Jul 2026

Researchers train AI to detect diabetes and assign four diagnostic labels

Researchers developed a two-stage machine learning framework that detected diabetes and classified records as prediabetes, type 1, type 2, or type 3c diabetes using two public datasets. XGBoost showed strong internal performance, but inconsistent model rankings, non-standard variables, and the absence of external clinical validation limit immediate use.

29 Jul 2026

New home test uses thigh length to detect type 2 diabetes or prediabetes

A new home test can detect type 2 diabetes or prediabetes with high accuracy. The test has been developed using artificial intelligence and large amounts of health data – and surprisingly, one of the steps involves measuring the length of your thigh.

29 Jul 2026

ACLM launches Project Remission to shift the goal of chronic disease care

The American College of Lifestyle Medicine (ACLM) today announced the launch of Project Remission, a call to action to shift the goal of chronic disease care from symptom management to the possibility of achieving remission and health restoration.

29 Jul 2026

Father's diet before conception impacts baby's body composition

A father's diet can affect his children's health and body composition before they are even conceived. A study of 43 triads of fathers, mothers, and newborns treated in the public healthcare system of Ribeirão Preto in the state of São Paulo, Brazil, demonstrated this.

28 Jul 2026

Nutritional quality matters more than processing level for long-term health

What makes a diet healthy-or not? According to a new study, nutritional quality matters more than processing level when it comes to long-term health.

28 Jul 2026

Taste preference genes drive overeating and metabolic disease risk

Ever wonder why some people crave sweets while others can take them or leave them? Preliminary findings from a new study suggest that people who carry certain genetic variants associated with a preference for sweet or fatty tastes not only tend to eat more of these foods but also have a higher risk of obesity and type 2 diabetes as a result.

27 Jul 2026