Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Insulin Resistance Symptoms

Does the Keto Diet Increase the Risk of Diabetes?

Type 2 Diabetes Screening and Prevention

What is Diabetes?

Insulin Resistance Pathophysiology

Insulin Medication

Is a Plant-Based Diet Good for Type 2 Diabetes?

Fibromyalgia and Diabetes

Type 2 Diabetes Diagnosis

Living With Type 2 Diabetes

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

See more featured articles »

Insulin Resistance Treatment

Type 2 Diabetes Treatment

Vitamin D and Type 2 Diabetes

Type 2 Diabetes Symptoms

Diabetes in Men versus Women

What is Insulin Resistance?

Insulin Resistance and Parkinson's Disease

Diabetes Mellitus Type 2 Pathophysiology

The Risks of Prediabetes

Insulin Resistance Diagnosis

Causes of Insulin Resistance

Latest Type 2 Diabetes News and Research

Modest changes to diet could deliver environmental and health benefits

Modest changes to meat and dairy consumption could help Scotland meet climate goals while improving health and nutrition, research shows.

3 Jul 2026

GLP-1 medications may improve long-term health for people with peripheral artery disease

GLP-1 receptor agonists (GLP-1 RA) medications were shown to reduce the number of deaths, amputations and hospitalizations among people with Type 2 diabetes who also had narrowed leg arteries associated with PAD (peripheral artery disease), according to new, independent research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

1 Jul 2026

Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care

A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

1 Jul 2026

Experts reframe steatotic liver disease as a dynamic continuum

The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof. Tacke from Charité - Universitätsmedizin Berlin argue that metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD) should not be regarded as rigid diagnostic categories, but rather as interconnected and evolving disease trajectories.

30 Jun 2026

Okra supplements may lower cholesterol and inflammation markers in diabetes

...

29 Jun 2026

Study links sedentary lifestyle to early mitochondrial dysfunction in adults

Researchers at the University of Colorado Anschutz have found that healthy yet sedentary individuals show a significant, coordinated drop in muscle mitochondrial function that may precede the development of major diseases like cancer, diabetes, and Alzheimer's.

29 Jun 2026

Young adults miss health benefits by neglecting primary care doctors

A new survey commissioned by The Ohio State University Wexner Medical Center finds young adults are missing out on the health benefits of having a primary care doctor.

29 Jun 2026

Simple blood test could identify the most effective obesity drug

Fasting blood tests measuring GLP-1 and GIP levels may predict obesity treatment response to semaglutide and tirzepatide, enhancing personalized therapy.

29 Jun 2026

Hearing aids may lower dementia risk in adults with epilepsy and hearing loss

Adults with both epilepsy and hearing loss who use hearing aids may have a 23% lower risk of developing dementia than those who do not, according to new research presented at the European Academy of Neurology (EAN) Congress 2026.

26 Jun 2026

Single DNA injection provides long-lasting weight loss in mouse study

Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic instructions can produce weight loss and blood glucose control in murine models that lasts up to 10 times as long as incretin-mimicking drugs like Ozempic and Wegovy.

26 Jun 2026

Semaglutide approval drove a surge in GLP-1 poison center exposures

Following semaglutide's approval, poison center reports of GLP-1 RA exposures doubled, revealing critical trends in patient safety and healthcare utilization.

26 Jun 2026

Childhood sugary drinks and fruit juice linked to higher adult blood pressure risk

The study finds sugary drinks and fruit juice linked to hypertension, highlighting whole fruit as a healthier alternative for long-term heart health.

26 Jun 2026

Bariatric surgery linked to higher risk of developing alcohol problems

Your body absorbs alcohol much more rapidly after bariatric surgery. Patients need to know this when they choose the kind of surgery they will have.

25 Jun 2026

Recognizing perinatal heart failure early reduces life-threatening risks

Early detection and timely treatment of heart failure in pregnant or postpartum women are crucial to prevent serious complications, such as irregular heartbeat, stroke and death, according to a new American Heart Association scientific statement, "Heart Failure Occurring in the Perinatal Period."

25 Jun 2026

Scientists map blood chemistry links to hundreds of diseases

A UK Biobank study of nearly 390,000 people mapped 251 NMR-derived plasma metabolic traits against hundreds of health traits, prevalent diseases, and future disease outcomes. The atlas revealed tens of thousands of replicated associations, showed stronger prediction for selected short-term and cardiometabolic outcomes, and identified putative causal links that may guide future precision medicine research.

24 Jun 2026

Concerns about weight regain after yo‑yo dieting are largely unfounded, review shows

Many people experience fluctuations in body weight throughout their lives, and so‑called yo‑yo dieting has long been considered a health risk – in some cases even more harmful than remaining overweight.

24 Jun 2026

Plant-based Mediterranean-style diet cuts heart disease risk by 26%

A 20-year study links plant-based Mediterranean diets to lower heart disease risk, highlighting the importance of sustainable eating for cardiovascular health.

24 Jun 2026

Early diabetes drug treatment links to better survival after diagnosis thresholds

A Korean target trial emulation found that starting antidiabetic medication within 12 months of newly crossing type 2 diabetes diagnostic thresholds was associated with lower five-year all-cause mortality. MACE risk was numerically lower with earlier treatment, but the reductions in cardiovascular events were not statistically significant, underscoring the need for larger studies.

24 Jun 2026

Strength training plus cardio cuts type 2 diabetes risk the most

A 20-year prospective cohort study of 143,715 US healthcare professionals found that long-term resistance training was associated with a substantially lower risk of type 2 diabetes. The lowest risk was seen among participants who combined regular resistance training with adequate aerobic activity and limited TV viewing.

23 Jun 2026

USC study links modified Mediterranean diet to longer lifespan

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

23 Jun 2026