Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Diabetes Mellitus Type 2 Pathophysiology

Type 2 Diabetes Symptoms

Type 2 Diabetes Diagnosis

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

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Latest Type 2 Diabetes News and Research

Cardiovascular risk factors accumulated from childhood linked to poorer brain function at midlife

Managing weight, blood pressure and cholesterol in children may help protect brain function in later life, according to new research published today in the American Heart Association's flagship journal Circulation.

10 May 2021

Inflammasomes could play an important role in the development of obesity-related colon cancer

New research presented at this year's European Congress on Obesity (held online, 10-13 May) finds evidence that structures called inflammasomes (a part of the innate immune system that helps to regulate inflammation) could play an important role in the development of obesity-associated colon cancer.

10 May 2021

Researchers reveal how to effectively achieve and maintain a healthy weight loss

Almost one in five Danes live with obesity, which may have serious health consequences. In the world's most recognized medical journal, Danish researchers now document how to effectively achieve and maintain a healthy weight loss.

6 May 2021

Regular consumption of sardines helps prevent the onset of type 2 diabetes

The health benefits of sardines and oily fish are widely known: their high levels of unsaturated fats help to regulate cholesterol levels and prevent the onset of cardiovascular diseases. However, the benefits don't end there.

6 May 2021

Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk

Drinking two or more daily sugar-sweetened beverages in adulthood is linked to a doubling in the risk of bowel cancer before the age of 50--at least in women, finds research published online in the journal Gut.

6 May 2021

Prediabetes can boost a person's chance of major cardiovascular events

People with prediabetes were significantly more likely to suffer a heart attack, stroke or other major cardiovascular event when compared with those who had normal blood sugar levels, according to research being presented at the American College of Cardiology's 70th Annual Scientific Session.

5 May 2021

Stress levels of moms with preschoolers increased during the pandemic

Stress levels of moms with preschoolers soared during the pandemic, with twice as many of the mothers reporting they lost sleep during the COVID-19 outbreak than before it.

5 May 2021

FDA approves new drug for treatment of adults with chronic kidney disease

Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression.

30 Apr 2021

Wearable devices offer new insights into the progression of Type 2 diabetes in Latino adults

In one of the first studies of its kind, medical and engineering researchers have shown wearable devices that continuously monitor blood sugar provide new insights into the progression of Type 2 diabetes among at-risk Hispanic/Latino adults.

30 Apr 2021

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine

Last Friday, the Centers for Disease Control and Prevention and the U.S. Food & Drug Administration lifted the pause in administration of the Johnson & Johnson (Janssen) COVID-19 vaccine in the U.S.

29 Apr 2021

Lifestyle education program helps increase moderate-to-vigorous intensity physical activity

D-CLIP, a lifestyle education program to prevent diabetes in South Asians with prediabetes, increased moderate-to-vigorous intensity physical activity (MVPA) by up to nearly an hour a week, researchers at the Rush Institute for Healthy Aging have found.

29 Apr 2021

Surge of pediatric patients with diabetic ketoacidosis during COVID-19 pandemic

According to the Centers for Disease Control and Prevention (CDC), children generally appear to be less severely impacted by COVID-19 than adults.

26 Apr 2021

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

The University of Southern Denmark, Rigshospitalet and the University of Copenhagen have come together to study the effects of Football Fitness on various health parameters and self-rated health following treatment for breast cancer.

26 Apr 2021

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

The hormonal therapies used to treat many breast and prostate cancers raise the risk of a heart attack and stroke, and patients should be monitored regularly and receive treatment to reduce risk and detect problems as they occur.

26 Apr 2021

Study links muscle gene to type 2 diabetes

People with type 2 diabetes tend to have poorer muscle function than others. Now a research team at Lund University in Sweden has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells.

23 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded a team of UTHSC researchers $1.99 million for their work to advance understanding of the pathophysiology of prediabetes, diabetes, and related complications.

22 Apr 2021

California and Texas took different routes to vaccination. Who’s ahead?

California and Texas, the country's two most populous states, have taken radically different approaches to the pandemic and the vaccination campaign to end it.

22 Apr 2021

Researchers develop new mathematical model to predict the onset of diseases

A myriad of genetic factors can influence the onset of diseases like high blood pressure, heart diseases, and type 2 diabetes.

20 Apr 2021

Once-a-week injectable insulin therapy proves to be safe, effective in people with Type 2 diabetes

Treating people with Type 2 diabetes with a new once-a-week injectable insulin therapy proved to be safe and as effective as daily insulin injections, according to the results of two international clinical trials published online today in Diabetes Care.

19 Apr 2021