Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

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Type 2 Diabetes Symptoms

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Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

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What is Insulin Resistance?

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Latest Type 2 Diabetes News and Research

Maintaining VDR levels in pancreatic cells could protect against diabetes

Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of the disease.

27 Mar 2020

Factors causing childhood obesity differ for wealthier and poorer countries

Childhood obesity is not just a public health concern in western countries; it is rising across the world, particularly in poor and low-income countries.

26 Mar 2020

Study suggests potential therapeutic strategy against diabetes

Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin (β cells) could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of the disease.

26 Mar 2020

Culturally adapted diabetes education programs boost Latino participation

An Oregon State University study published last week found that diabetes education programs that are linguistically and culturally tailored to Latinos lead to significantly higher rates of completion among Latino participants -- even higher than rates among non-Latinos enrolled in the English versions of those programs.

25 Mar 2020

Men who had early puberty at higher risk of type 2 diabetes

A man who experienced the onset of puberty earlier than usual is at a higher risk of developing type 2 diabetes as an adult, compared to boys who have later puberty. This trend does not depend on childhood weight. The study, published in the journal Diabetologia in March 2020, may help establish guidelines for prevention and testing for diabetes in men.

23 Mar 2020

Research may help older adults maintain skeletal muscle mass and physical function for longer

Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria.

22 Mar 2020

Participation of people with diabetes in online support groups associated with poorer health

Diabetes is a disease that affects people's lives more in the long term and requires emotional support and information. It is increasingly common for people with diabetes to participate in digital communities and seek help in so-called OSGs (online support groups) to share experiences and glean information.

19 Mar 2020

Weight loss lasts long after bariatric surgery, study finds

Weight loss was maintained better after gastric bypass than after sleeve gastrectomy in large study of diverse patients in Washington and California.

17 Mar 2020

Reports of flu-like symptoms seen with Keto diet

A new study has shown that those starting on a keto diet could develop certain flu-like symptoms in the initial weeks. The study titled, “Consumer Reports of “Keto Flu” Associated With the Ketogenic Diet,” was published in the latest issue of the journal Frontiers in Nutrition.

15 Mar 2020

Survey: Support for long-term health implications of PCOS is lacking

Treating polycystic ovary syndrome as only a fertility condition is leaving those with the condition at greater risk of developing related long-term health conditions, according to women surveyed and interviewed in University of Warwick research.

12 Mar 2020

Scientists identify genes involved in the development of diabetic kidney disease

By analyzing samples from hundreds of Finns with diabetes, scientists have identified genes, and the proteins they encode, that could be involved in the development of diabetic kidney disease.

12 Mar 2020

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Breathing dirty air takes a heavy toll on gut bacteria, boosting risk of obesity, diabetes, gastrointestinal disorders and other chronic illnesses, new University of Colorado Boulder research suggests.

11 Mar 2020

Healthy lifestyle for longer keeps disease at bay

Researchers from the Boston University School of Medicine have conclusively found that increased time spent leading a healthy lifestyle during midlife can keep certain diseases at bay and promote good cardiovascular health.

11 Mar 2020

UCR project receives funding to improve Latino population's access to healthy local foods

The University of California, Riverside, has been approved for a nearly $300,000 funding award through the Eugene Washington PCORI Engagement Awards program, an initiative of the Patient-Centered Outcomes Research Institute.

10 Mar 2020

Bacteria may be involved in the development of type 2 diabetes, study shows

Bacteria may be involved in the development of type 2 diabetes, according to a study published today in Nature Metabolism by researchers from Université Laval, the Québec Heart and Lung Institute, and McMaster University.

9 Mar 2020

Biomarker in saliva linked to emergence of childhood obesity

A molecular marker in saliva is associated with the emergence of childhood obesity in a group of preschool-aged Hispanic children.

7 Mar 2020

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Cleveland Clinic researchers have identified a gut microbe generated byproduct - phenylacetylglutamine - that is linked to development of cardiovascular disease, including heart attack, stroke and death.

5 Mar 2020

Newly developed mobile app helps reduce pain in osteoarthritis patients

By performing a few simple physical exercises daily, and receiving information about their disease regularly, 500 osteoarthritis patients were able to on average halve their pain in 6 months - and improve their physical function.

5 Mar 2020

Dietary changes may prevent or reverse age-related effects in the brain

A study using neuroimaging led by Stony Brook University professor and lead author Lilianne R. Mujica-Parodi, PhD, and published in PNAS, reveals that neurobiological changes associated with aging can be seen at a much younger age than would be expected, in the late 40s.

5 Mar 2020

Type 2 diabetes mellitus responds to weight loss surgery

Type 2 diabetes mellitus (T2DM) is a metabolic condition with close links to weight gain. Since weight loss is a proven way to control T2DM, it is to be expected that surgeries to achieve weight loss should result in better regulation of blood glucose levels.

4 Mar 2020