Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Diabetes Mellitus Type 2 Pathophysiology

Type 2 Diabetes Symptoms

Type 2 Diabetes Diagnosis

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

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Diabetes in Men versus Women

Insulin Medication

Latest Type 2 Diabetes News and Research

Modulating the rap1 mechanism can help control blood sugar levels

Managing type 2 diabetes typically involves losing weight, exercise and medication, but new research by Dr. Makoto Fukuda and colleagues at Baylor College of Medicine and other institutions suggests that there may be other ways to control the condition through the brain.

23 Jun 2021

Protein blueprint may aid in treatments for infertility and help protect future fertility

Researchers at the University of Cincinnati College of Medicine have developed a blueprint for a protein that plays an important role in the development and regulation of reproductive organs.

22 Jun 2021

Researchers discover a new mechanism controlling satiation

Researchers from the Turku PET Centre and Technical University of Munich have discovered a new mechanism controlling satiation. According to the recently published study, the hormone secretin induces satiation by activating brown adipose tissue.

22 Jun 2021

Mother's gestational diabetes is an independent risk factor for fetal hypoxia during labor

In Finland, every fifth mother was diagnosed with gestational diabetes in 2019. The condition increases the mother's risk of developing type 2 diabetes in the future.

22 Jun 2021

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

In recent years, significant progress has been made towards the use of high-resolution peripheral computed tomography (HR-pQCT) imaging in research, and new potential for applications in the clinic have emerged, particularly with the advent of second generation devices.

18 Jun 2021

High junk food consumption in childhood increases risk of unhealthy body fat by early adulthood

A new paper published recently in the journal JAMA Pediatrics reports consistent and significant associations between the increased consumption of such ‘ultraprocessed foods’ by children in the UK, and a higher risk of obesity, increased body fat percentage, and overall body mass, by the time they reach young adulthood.

17 Jun 2021

New model identifies effective dissemination strategies for Type 2 diabetes guidelines

Health care workers often don't adopt new guidelines for best practices in medical care until well after those guidelines are established.

17 Jun 2021

Low-fiber, high-fat diets cause significant shifts in the gut microbiome

Changes to gut microbiome are known to impact metabolic health. Physiologists at Laval University in Canada have discovered that diets containing low fiber and high fat cause significant shifts in the gut microbiome-;the collection of bacteria, viruses, fungi and other multicellular microorganisms that live in the gastrointestinal system.

15 Jun 2021

Change in diet and circadian clock can impact healthy fat tissue, finds study

Changing your eating habits or altering your circadian clock can impact healthy fat tissue throughout your lifespan, according to a preclinical study published today in Nature by researchers with The University of Texas Health Science Center at Houston.

15 Jun 2021

Examining how the consumption of ultra-processed foods increases adiposity in children

A recent paper discusses the positive association that exists between the consumption of ultra-processed foods and adiposity measurements from children.

15 Jun 2021

High proportion of people with diabetes have chronic kidney disease, research reveals

Some 42% of patients attending a dedicated diabetes clinic have signs of established chronic kidney disease, the first detailed research of its kind in Ireland has revealed.

14 Jun 2021

Study shows poor antibody response in naive elderly of nursing homes after mRNA vaccination

A new study describes inadequate antibody responses to the Pfizer/BioNTech vaccine against coronavirus disease 2019 (COVID-19) in elderly residents of a care home with no prior history of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), compared to those with such a history. This adds to the current understanding of vaccine efficacy against infection.

13 Jun 2021

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.

11 Jun 2021

Study implicates placental protein as a possible regulator of an infant’s birthweight

New findings from the University of Minnesota Medical School are helping uncover why some people are more likely to be overweight and develop Type 2 diabetes -- and it starts in the womb.

10 Jun 2021

Study offers new perspective on disproportionate impact of COVID-19

A new analysis by researchers at Massachusetts General Hospital (MGH) offers a novel perspective on the disproportionate impact that COVID-19 has had on people of color, low-income populations, and other structurally disadvantaged groups.

10 Jun 2021

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

New bacterium shows promise for treating type 2 diabetes, obesity

It all started, when Patrice Cani, FNRS researcher at University of Louvain (UCLouvain), and his team repeatedly observed that a bacterium (called Subdoligranulum) is almost absent in obese and diabetic people, while it is systematically present in healthy people. So, they decided to take a closer look at this "family" of bacteria.

9 Jun 2021