Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Diabetes Mellitus Type 2 Pathophysiology

Type 2 Diabetes Symptoms

Type 2 Diabetes Diagnosis

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

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Latest Type 2 Diabetes News and Research

Artificial pancreas may soon help patients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of Bern, Switzerland, show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.

4 Aug 2021

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

4 Aug 2021

Study offers genetic insights into the underlying biology of reproductive aging

The age at which women go through menopause is critical for fertility and impacts healthy ageing in women, but reproductive ageing has been difficult for scientists to study and insights into the underlying biology are limited.

4 Aug 2021

Next-Generation Sequencing and the Diagnosis of Disease

In this interview, Professor John Rossen talks about next-generation sequencing and it's implications for the diagnosis of disease.

From Tecan 4 Aug 2021

Comprehensive study of Middle Eastern DNA reveals ancient human adaptation to agriculture, climate change

The most comprehensive study so far of genetic diversity in the Middle East has given a glimpse into the lives of ancient humans who lived through such seismic events as the development of agriculture and the formation of the Arabian Desert.

4 Aug 2021

Surplus sugar may cause our cellular powerplants to become less efficient, finds study

The average American eats roughly 22 teaspoons of added sugar a day -; more than three times the recommended amount for women and more than double the recommended amount for men.

3 Aug 2021

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.

3 Aug 2021

Diabetes drug’s new weight loss formula fuels cost-benefit debate

The long list of side effects that follow ads for the newer expensive drugs to treat Type 2 diabetes sometimes include an unusual warning: They might cause weight loss. That side effect is one that many people — especially those with Type 2 diabetes, which is associated with obesity — may desperately want.

30 Jul 2021

Youth-onset type 2 diabetes is more aggressive and difficult to control, study shows

People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis.

28 Jul 2021

First interchangeable biosimilar insulin product approved by FDA for treatment of diabetes

Today, the U.S. Food and Drug Administration approved the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus.

28 Jul 2021

Weight loss not given sufficient priority in the management of heart patients

Weight loss is given insufficient priority in the management of heart patients despite the benefits, according to a study published today in European Heart Journal - Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology.

27 Jul 2021

Excessive body fat can increase the risk of dementia

It's the global epidemic that affects two in every five adults, but as obesity continues to expand waistlines worldwide, researchers at the University of South Australia are warning that harmful body fat can also increase the risk of dementia and stroke.

26 Jul 2021

Study evaluates physical activity and sedentary behavior in relation to OSA risk

Being more physically active and spending fewer hours per day sitting watching TV is linked to a substantially lower risk of developing obstructive sleep apnea (OSA), according to new research published in the European Respiratory Journal

21 Jul 2021

Analysis: Necessary or not, covid booster shots are probably on the horizon

The drugmaker Pfizer recently announced that vaccinated people are likely to need a booster shot to be effectively protected against new variants of covid-19 and that the company would apply for Food and Drug Administration emergency use authorization for the shot.

21 Jul 2021

Patient's case report reveals link between Bell’s palsy and Pfizer-BioNTech vaccine

The case of a patient who experienced two facial palsies – one after the first and another after the second dose of the Pfizer-BioNTech COVID-19 vaccine – strongly suggests that Bell’s palsy (facial nerve palsy of unknown cause) is linked to the Pfizer-BioNTech vaccine, doctors write in the journal BMJ Case Reports.

19 Jul 2021

Study highlights burden of methamphetamine-associated heart failure hospitalizations in California

Heart failure hospitalizations and costs related to methamphetamine use jumped sharply over a decade in California, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

14 Jul 2021

Study: Diet rich in fermented foods boosts microbial diversity, decreases inflammation

A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers at the Stanford School of Medicine.

12 Jul 2021

Athletes more likely to experience irregular heart rhythms than non-athletes

Athletes appear to be almost two and half times more likely than non-athletes to experience irregular heart rhythms, suggests new research published in the British Journal of Sports Medicine.

12 Jul 2021

Study examines the role of early blood-sugar levels after diagnosis of type 2 diabetes

People who get type 2 diabetes need to gain control of their blood-sugar levels -- fast. The years immediately after diagnosis are strikingly critical in terms of their future risk for heart attacks and death. This is shown by a joint study from the Universities of Gothenburg and Oxford.

9 Jul 2021

Study finds why young South Asian heart attack patients have more adverse outcomes

A new study examining why young South Asian heart attack patients have more adverse outcomes found this patient population was often obese, used tobacco products, and had a family history of heart disease or risk factors that could have been prevented, monitored for or treated before heart attacks happen.

7 Jul 2021