Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

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Latest Type 2 Diabetes News and Research

Blood pressure drug losartan boosts metabolism by stimulating brown fat

Losartan, a drug commonly prescribed for high blood pressure, boosts brown adipose tissue or "brown fat" activity and enhances its metabolism, according to a preclinical study by Weill Cornell Medicine, Rockefeller University and Memorial Sloan Kettering Cancer Center researchers.

19 Oct 2026

Miro1 protein linked to insulin resistance in type 2 diabetes

A protein called Miro1 found at elevated levels in the skeletal muscle of people with Type 2 diabetes may contribute to insulin resistance, potentially making it a target for future treatments that help the body regulate blood sugar, according to a study published today in Nature Communications.

19 Oct 2026

Voice frequency patterns reveal clues linked to type 2 diabetes

A new research study in theIEEE Journal of Biomedical and Health Informatics reveals how scientists at Klick Labs created visual maps of sound frequencies (spectrograms) to identify complex, new patterns associated with Type 2 diabetes, using only smartphone recordings of randomly selected short English sentences and participant sex as study criteria.

19 Oct 2026

Parents know fruit and vegetables are healthy, but many underestimate how much children need

A qualitative study involving 15 Swedish parents found that although most recognized the health benefits of fruit and vegetables, many underestimated recommended daily intake and considered serving vegetables at dinner sufficient. Researchers identified four overlapping parental roles influencing children's eating habits and suggested that clearer guidance on quantities, serving frequency, and practical feeding approaches could help families improve consumption.

15 Oct 2026

AI study of 101,000 patients links brown fat to heart and mental health

In a retrospective analysis of PET-CT records from 101,243 patients, researchers found that detectable brown fat was associated with lower prevalence of cardiometabolic and psychiatric conditions, while greater activity, particularly in the axillary region, was linked to more favourable metabolic outcomes. Medication screening identified losartan, which increased brown fat thermogenic activity in laboratory experiments and energy expenditure in mice, although its effects on human brown fat remain unproven.

15 Oct 2026

Study: First 90 days of antipsychotic treatment critical for metabolic changes

The first 90 days after starting antipsychotic treatment are crucial for changes in blood sugar and weight, finds a new study led by UCL researchers.

14 Oct 2026

Novel bioprinting technique successfully replicates mature human fat tissue

A research team has developed a support-bath bioprinting method that enables fragile, mature human adipocytes to be incorporated into geometrically defined three-dimensional (3D) constructs while retaining their viability, characteristic lipid-filled morphology, and metabolic activity.

14 Oct 2026

Chronic inflammation spikes during the earliest phase of cardiovascular-kidney-metabolic syndrome

In a nationally representative sample of more than 4,000 American adults, a common marker of inflammation was nearly doubled in people in the first stage of the syndrome, defined by excess or unhealthy body fat, compared with those with no metabolic risk factors.

14 Oct 2026

From turmeric to fenugreek, scientists examine nature’s potential role in diabetes care

A narrative review examined how curcumin, honey, culinary spices, and traditional remedies may influence oxidative stress, inflammation, mitochondrial function, and insulin signaling in diabetes. Although experimental research and some clinical trials suggest potential metabolic benefits, the authors emphasize that larger, well-controlled studies are needed to establish their effectiveness and safety alongside conventional treatments.

14 Oct 2026

Doctors avoided two common words when talking about weight with patients

Researchers analyzed 123 recorded primary care consultations involving adults with type 2 diabetes and elevated BMI, finding that weight was discussed in just 39% of visits. Clinicians avoided potentially stigmatizing terms such as "overweight" and "obesity," while weight-related conversations occurred more frequently among patients taking GLP-1 receptor agonists.

13 Oct 2026

ACLM launches resources to meet new medical nutrition requirements

The American College of Lifestyle Medicine (ACLM) has launched two resources to help medical schools meet new federal nutrition requirements and to support practicing physicians seeking education relevant to state-level nutrition education requirements.

13 Oct 2026

Major trial seeks to test semaglutide on adults with alcohol and opioid use disorder

The Center for Addiction Science, Policy and Research (CASPR) and the Allegheny County Department of Human Services are preparing to launch a major $13.3 million randomized controlled trial to test whether weekly semaglutide, as an additional support to existing care, can reduce alcohol and opioid use and reduce criminal-justice involvement while improving employment, health, and housing outcomes among people at elevated risk of criminal-justice involvement.

13 Oct 2026

Three months of yoga before surgery revealed a surprising difference in stress hormones

In a non-randomized study of 40 adults with severe obesity awaiting bariatric surgery, researchers found significantly lower plasma noradrenaline levels in yoga participants than in controls after adjusting for baseline measurements. The researchers detected no significant DNA methylation changes in three inflammatory genes and found no clear psychological or metabolic benefits.

12 Oct 2026

Targeting lipophagy could help treat metabolic and oxidative stress-related diseases

A review published in Genes & Diseases highlights lipophagy, the cellular process that selectively breaks down lipid droplets, as a potentially important therapeutic target for conditions driven by disrupted lipid metabolism and oxidative stress.

12 Oct 2026

Researchers followed glucose monitor users for three years and found a possible kidney benefit

A study of more than 25,000 analytical group assignments involving high-risk adults with type 2 diabetes found that sustained real-time continuous glucose monitoring (rtCGM) was associated with substantial improvements in blood sugar control over three years. Continued use was also linked to lower levels of a marker of kidney damage after three years, although researchers found no evidence that the technology preserved kidney filtration function.

12 Oct 2026

What people ate at the start of a 20-year study was linked to their heart failure odds

Researchers linked higher baseline diet quality to lower odds of developing heart failure over 20 years among 2,159 Greek adults initially free of cardiovascular disease. Healthy-food consumption showed the most consistent association, but the observational study cannot establish that dietary changes prevent heart failure.

11 Oct 2026

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Effective management of high blood pressure could prevent more than 518,000 annual deaths from cardiovascular disease around the world, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.

11 Oct 2026

Stopping GLP-1 drugs often brings weight back. A small trial suggests ways to slow it

In a randomized pilot trial of 39 adults, researchers found that participants receiving medically tailored meals or Noom regained about 3.6% of their body weight over four months after stopping GLP-1 therapy, compared with about 11% under usual care. These exploratory findings suggest structured support may slow early weight regain, but the small sample and short follow-up leave lasting benefits uncertain.

11 Oct 2026

Molecular regulator CA8 may offer new therapeutic target for type 2 diabetes

Maintaining healthy blood glucose levels involves striking a balance between the glucose produced by the liver during fasting, and the insulin released from pancreatic beta cells after meals.

9 Oct 2026

Cutting sugary drinks helps reduce childhood obesity, study finds

While the adult obesity rate appears to be slowing in the United States, childhood obesity remains historically high, affecting nearly 1 in 5 school-aged children.

9 Oct 2026