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Scientists reveal how cholera bacteria activate toxin genes in the human gut

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year.

14 Jan 2026

UC San Diego project aims to bioprint patient-specific transplantable human livers

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in the United States wait for a donor organ.

14 Jan 2026

$Six week casting proves as effective as surgery for unstable ankle fractures$

Six week casting proves as effective as surgery for unstable ankle fractures

Wearing a cast for six weeks appears to be no less effective than surgery for healing unstable ankle fractures and carries fewer treatment related harms, finds a clinical trial from Finland published by The BMJ today.

14 Jan 2026

Pulse oximeters overestimate blood oxygen levels in patients with darker skin

Fingertip monitors known as pulse oximeters that can be used at home to detect low blood oxygen levels (hypoxaemia) give higher readings for patients with darker than lighter skin tones, finds the largest study on this topic published by The BMJ today.

14 Jan 2026

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.

14 Jan 2026

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

14 Jan 2026

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.

14 Jan 2026

Phase II clinical trial shows promising results for novel sepsis drug

Griffith University researchers may have unlocked the secret to treating sepsis, with a Phase II clinical trial in China successfully concluding with promising results.

14 Jan 2026

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain.

14 Jan 2026

Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, according to a new study published January 14, 2026 in the open-access journal PLOS One by Ana Maldonado-Contreras of University of Massachusetts Chan Medical School, U.S., and colleagues.

14 Jan 2026

Study reveals genetic signatures linked to HIV-related cognitive impairment

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

14 Jan 2026

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

New chemistry revives neurokinin-1 receptor as depression treatment target

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder.

14 Jan 2026

AI tool helps clinicians quickly understand complex patient medical histories

An AI-guided platform at Penn Medicine allows clinicians to quickly and easily unearth pertinent information from patients’ electronic health records that otherwise might have been difficult to find.

14 Jan 2026

Dietary intervention eases celiac symptoms in children but not quality of life

The Gluten3S research group launched a dietary intervention with children who had recently been diagnosed with celiac disease.

14 Jan 2026

Hearing aid use has little impact on cognitive test scores

A new study has found that for people with moderate hearing loss, being prescribed hearing aids had little impact on cognitive test scores.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death.

14 Jan 2026

Age-tailored therapies needed for treating the young and old with sepsis

Dealing with an infection isn't as straightforward as simply killing the pathogen. The body also needs to carefully steer and monitor its immune response to prevent collateral damage.

14 Jan 2026

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Medical News

Scientists reveal how cholera bacteria activate toxin genes in the human gut

UC San Diego project aims to bioprint patient-specific transplantable human livers

Six week casting proves as effective as surgery for unstable ankle fractures

Pulse oximeters overestimate blood oxygen levels in patients with darker skin

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

Phase II clinical trial shows promising results for novel sepsis drug

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

Study reveals genetic signatures linked to HIV-related cognitive impairment

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

New chemistry revives neurokinin-1 receptor as depression treatment target

AI tool helps clinicians quickly understand complex patient medical histories

Dietary intervention eases celiac symptoms in children but not quality of life

Hearing aid use has little impact on cognitive test scores

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Age-tailored therapies needed for treating the young and old with sepsis

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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