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AI model ranks genetic variants from severe to mild disease mutations

popEVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant scoring for rare diseases.

3 Dec 2025

AEDs on planes could save lives, study urges global policy change

In-flight cardiac arrest is extremely rare, yet catastrophic, and responsible for up to 86 % of all deaths in the air. A new comprehensive literature review highlights systemic and policy shortcomings of current aviation safety standards, calling for global alignment.

3 Dec 2025

New method reveals how human cells initiate DNA replication

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, and genetic disorders. Therefore, understanding how cells replicate their DNA is crucial for elucidating fundamental biological processes, diseases, and even evolution.

3 Dec 2025

Stem cells reshape in response to electrical signals, study reveals

Scientists in Melbourne have discovered how tiny electrical pulses can steer stem cells as they grow, opening the door to new improved ways of creating new tissues, organs, nerves and bones.

3 Dec 2025

DNA language model performance hinges on pre-training data choices

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models.

3 Dec 2025

Automated EHR system triages cancer symptoms, improves care team efficiency

For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.

3 Dec 2025

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

An updated Cochrane review has found that calcium supplementation has no effect on pre-eclampsia, challenging long-held assumptions about the role of calcium in preventing hypertensive disorders in pregnancy.

3 Dec 2025

Rentschler Biopharma and Coriolis Pharma announce strategic collaboration for integrated biopharma solutions

Rentschler Biopharma, a leading global contract development and manufacturing organization (CDMO) for biopharmaceuticals, and Coriolis Pharma, a globally operating contract research and development organization (CRDO) and a leader in formulation research and development for biopharmaceuticals, today announced a strategic collaboration.

From Rentschler Biopharma SE 2 Dec 2025

Gene variant linked to higher risk of chronic rejection after lung transplant

About one third of lung transplant recipients have a genetic variant that makes them more likely to develop chronic lung allograft dysfunction (CLAD), the primary cause of mortality after lung transplantation.

2 Dec 2025

Study reveals the overlooked mental health challenges faced by new parents

Intrusive thoughts and psychotic-like experiences among new parents are far more common than previously thought - according to new research from the University of East Anglia.

2 Dec 2025

Rice researchers develop resettable serum markers for clearer brain activity signals

Tracking how genes switch on and off in the brain is essential for understanding many neurological diseases, yet the tools to monitor this activity are often invasive or unable to capture subtler changes over time.

2 Dec 2025

Nearly one million young children die each year due to growth failure worldwide

Nearly one million children around the globe fail to reach their fifth birthday every year due to devastating health consequences linked to child growth failure, making it the third leading risk factor for mortality and morbidity in children under five.

2 Dec 2025

Maternal eating disorders linked to higher asthma and wheezing risks in children

Eating disorders in mums-to-be are linked to a heightened risk of asthma and wheezing in their children, irrespective of the type of disorder, presence of co-existing depression/anxiety, or the timing of their child's exposure, finds research published online in the journal Thorax.

2 Dec 2025

Experts call for comprehensive measures to reduce injury risks for female athletes

reating a safe, gender-specific, supportive environment-one that is free of body shaming and idealised female forms, for example-is key to minimising female athletes' future risks of injury and protecting their health, emphasizes the Female/woman/girl Athlete Injury pRevention (FAIR) Consensus Statement-the first of its kind-published online in the British Journal of Sports Medicine.

2 Dec 2025

Hospital payment caps linked to savings and stable care in Oregon

As health care costs continue to soar across the U.S., a growing number of states are setting limits on how much hospitals can charge.

2 Dec 2025

SCAI and CRT launch partnership to expand innovation and training in interventional cardiology

The Society for Cardiovascular Angiography & Interventions (SCAI) and Cardiovascular Research Technologies (CRT) today announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives.

2 Dec 2025

Fragmented sleep worsens recovery outcomes after traumatic brain injury

A new study highlights how important uninterrupted sleep is to recovery after a traumatic brain injury, finding that fragmented sleep in injured mice is linked to a loss of rapid-eye-movement (REM) sleep and increased fatigue.

2 Dec 2025

Hallucinogen-related hospital care linked to higher risk of future mania

People who have received emergency or hospital care in Canada due to hallucinogen use have a six-fold increased risk of receiving care for mania in the next three years, according to a study published December 2nd in the open-access journal PLOS Medicine by Daniel Myran from North York General Hospital in Canada and colleagues.

2 Dec 2025

Common water pill may be a useful add‑on to the standard HIV treatment

An FDA‑approved medication called spironolactone, often prescribed as a diuretic, or water pill, for heart and blood pressure conditions, may be a useful add‑on to the standard HIV treatment, according to new research from the Valente lab at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology.

2 Dec 2025