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Quest Diagnostics completes sale of ibrutinib commercialization rights to Royalty Pharma

Quest Diagnostics Incorporated, the world's leading provider of diagnostic information services, announced today that it has completed the sale of its rights to royalties from commercialization of the drug candidate ibrutinib to Royalty Pharma, the industry leader in acquiring royalty interests in marketed and late stage biopharmaceutical products, for $485 million in cash.

From Quest Diagnostics 18 Jul 2013

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Inovio Pharmaceuticals, Inc. announced today that the use of its proprietary electroporation technology significantly enhanced the ability of a DNA therapy to stimulate blood vessel growth, which may be beneficial for the treatment of critical limb ischemia and other forms of peripheral arterial disease.

18 Jul 2013

Scientists develop iKnife that helps surgeons identify cancerous tissues

Scientists have developed an "intelligent knife" that can tell surgeons immediately whether the tissue they are cutting is cancerous or not.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

UCI-led study point to new approach for treating foodborne illnesses

UC Irvine microbiologists have learned how a probiotic bacterium used to treat irritable bowel syndrome can soothe gut bacterial infections caused by Salmonella, paving the way for potential relief from foodborne illnesses that affect millions of people annually.

18 Jul 2013

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Creating and promoting foods that contain natural inhibitors of unhealthy angiogenesis - the formation of blood vessels that feed and promote disease, obesity and inflammation - is the "new frontier in dietary health," according to a presentation at the 2013 Institute of Food Technologists Annual Meeting & Food Expo- in Chicago.

18 Jul 2013

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Cancer researchers have wondered why ovarian cancer cells are so attracted to the abdominal cavity, especially the omentum, with the hope that such an understanding could lead to better disease management or even prevention.

18 Jul 2013

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

The National Institutes of Health has awarded Virginia Commonwealth University a grant totaling $1.8 million to study the biology of allergic disease - work which may one day point researchers to the development of therapies to fight asthma, allergy and inflammatory conditions such as rheumatoid arthritis, multiple sclerosis and heart disease.

18 Jul 2013

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

The study is reported on July 17, 2013, in an advance online edition of the journal Nature, alongside a British laboratory's structural study of another member of the same class of receptors-known as "class B" G protein-coupled receptors (GPCRs).

18 Jul 2013

Engineered liver tissue developed at MIT could help scientists test new drugs, vaccines for malaria

Although malaria has been eradicated in many countries, including the United States, it still infects more than 200 million people worldwide, killing nearly a million every year. In regions where malaria is endemic, people rely on preventive measures such as mosquito netting and insecticides. Existing drugs can help, but the malaria parasite is becoming resistant to many of them.

18 Jul 2013

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

Molecular biologists in the School of Medicine at The University of Texas Health Science Center San Antonio have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting effects.

18 Jul 2013

New class of WBCs in human lung and gut tissues play a critical role against fungal infections

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered a new class of white blood cells in human lung and gut tissues that play a critical role as the first line of defence against harmful fungal and bacterial infections.

18 Jul 2013

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

18 Jul 2013

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

For years, scientists have been worried about bisphenol A. The chemical is known as an "endocrine disruptor," a substance that interferes with the body's hormone signaling system, and it's found in everything from plastic drink bottles to the linings of food and drink cans to the thermal paper used for cash register receipts - not to mention the urine of 92.6 percent of Americans over the age of six.

18 Jul 2013

Microfuge 20 and 20R microcentrifuges from Beckman Coulter Life Sciences simplify setup, offer increased speed and capacity

Microfuge 20 and 20R microcentrifuges from Beckman Coulter are designed to meet the specific requirements of a wide range of research applications.

From Beckman Coulter Life Sciences - Centrifugation 17 Jul 2013

Rexahn Pharmaceuticals signs license agreement with UMB for novel drug delivery platform

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, announced today that it has signed an exclusive license agreement with the University of Maryland, Baltimore for a novel drug delivery platform, Nano-Polymer-Drug Conjugate Systems.

17 Jul 2013

Spectrum Pharmaceuticals enters into agreement to acquire Talon Therapeutics

Spectrum Pharmaceuticals, Inc., a biotechnology company with fully-integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced that, through a wholly-owned subsidiary, the company entered into an agreement to acquire Talon Therapeutics, Inc., a biopharmaceutical company based in South San Francisco, California, and expects to complete the acquisition within one day.

17 Jul 2013

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

The research couple receives the "2013 Khalid Iqbal Lifetime Achievement Award" for its role as pioneers in investigating the role of tau in Alzheimer's disease. The award ceremony was held yesterday (10:45 am US EST) within the framework of the "Alzheimer's Association International Conference (AAIC 2013)" in Boston (USA).

17 Jul 2013

Three scientists receive Young Investigator Award from Bert L. & N. Kuggie Vallee Foundation

The Bert L. and N. Kuggie Vallee Foundation announces, today, the first recipients of its Young Investigator Award.

17 Jul 2013

TAp73 protein frequently overexpressed in wide range of human tumors

They say you can pick your friends, but not your family. The same may hold true for related proteins. The protein TAp73 is a relative of the well-known, tumor-suppressor protein p53. It shares extensive common gene sequences with p53 and, as suggested by some previous studies, it may function similar to p53 to prevent tumor formation.

17 Jul 2013

Cell News and Research

Quest Diagnostics completes sale of ibrutinib commercialization rights to Royalty Pharma

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Scientists develop iKnife that helps surgeons identify cancerous tissues

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

UCI-led study point to new approach for treating foodborne illnesses

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

Engineered liver tissue developed at MIT could help scientists test new drugs, vaccines for malaria

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

New class of WBCs in human lung and gut tissues play a critical role against fungal infections

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

Microfuge 20 and 20R microcentrifuges from Beckman Coulter Life Sciences simplify setup, offer increased speed and capacity

Rexahn Pharmaceuticals signs license agreement with UMB for novel drug delivery platform

Spectrum Pharmaceuticals enters into agreement to acquire Talon Therapeutics

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

Three scientists receive Young Investigator Award from Bert L. & N. Kuggie Vallee Foundation

TAp73 protein frequently overexpressed in wide range of human tumors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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