Cell Death News and Research

RSS

Robotic microscope shows how mutant Huntington's disease protein affects neurons

Using a specially designed robotic microscope to study cultured cells, researchers have found evidence that abnormal protein clumps called inclusion bodies in neurons from people with Huntington's disease (HD) prevent cell death.

13 Oct 2004

Melanin is not only good for you, it also can be bad

Blondes and redheads not only are more susceptible to skin cancer, but the source of their skin and hair pigmentation, melanin, actually magnifies the damaging effects of ultraviolet (UV) rays, according to a study published online this week in the Proceedings of the National Academy of Sciences.

13 Oct 2004

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Duke University Medical Center researchers have shown that they can stimulate the body to produce its own naturally occurring growth factors to promote blood vessel growth into tissue damaged by peripheral arterial obstructive disease (PAOD).

13 Oct 2004

Researchers analyze the mechanisms and proteins that underlie mitochondria

New findings explaining the complicated process by which the "energy substations" of human cells split apart and recombine may lay the groundwork for new treatment approaches to a wide range of diseases, including some cancers and neurodegenerative diseases such as Parkinson's and Alzheimer's.

12 Oct 2004

Lithium can protect the brain cells involved in learning and memory from radiation damage

Patients who undergo radiation for treatment of brain tumors may survive their cancer only to have lasting memory and learning deficiencies, the impact of which can be particularly devastating for children.

10 Oct 2004

$10 million to establish a multidisciplinary research program in cancer nanotechnology

The National Institutes of Health (NIH) has awarded scientists from Emory University and the Georgia Institute of Technology two new collaborative research grants, totaling nearly $10 million, to establish a multidisciplinary research program in cancer nanotechnology and to develop a new class of nanoparticles for molecular and cellular imaging.

6 Oct 2004

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New research has opened up the prospect that gossypol – a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive – could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.

30 Sep 2004

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Phase II trials of the first second-generation antisense cancer drug to be used in patients are soon to be underway in the wake of a successful Phase I study, which has demonstrated that the new drug blocks its target gene in exactly the way it is designed to do.

28 Sep 2004

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Arsenic trioxide – a highly poisonous substance best known as an effective weed killer or pesticide and notorious for being a favourite ‘weapon’ of choice in murder mystery novels, is being re-invented as a treatment for a rare type of leukaemia.

28 Sep 2004

Researchers reduce the toxicity of water-soluble buckyballs by a factor of more than ten million

Researchers at Rice University's Center for Biological and Environmental Nanotechnology (CBEN) have demonstrated a simple way to reduce the toxicity of water-soluble buckyballs by a factor of more than ten million.

26 Sep 2004

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

Drinking a glass of red wine a day may cut a man's risk of prostate cancer in half, and the protective effect appears to be strongest against the most aggressive forms of the disease

23 Sep 2004

New link in the growth of Ewing’s sarcoma

To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor.

23 Sep 2004

New gene therapy technique may help treat Alzheimer's disease

Investigators at Rush University Medical Center have successfully initiated a new technique that uses gene therapy to deliver nerve growth factor into regions of the brain where neurons are degenerating, in order to prevent cell death and reverse cell atrophy, two hallmarks of Alzheimer's disease.

21 Sep 2004

Scientists have corrected a flaw in cancer cells that lets them evade the normal cell-death process

Scientists at Dana-Farber Cancer Institute have corrected a flaw in cancer cells that lets them evade the normal cell-death process, and as a result they eliminated leukemia cells from mice.

21 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Potential stem cells treatment for retinitis pigmentosa and other retinal degenerations

A team of researchers from The Scripps Research Institute was able to preserve visual function in mice that were genetically predisposed to developing a profound degenerative disease that destroys their retinas.

16 Sep 2004

Protein that causes juvenile Batten disease also plays a key role in normal cell function

The aberrant protein that causes juvenile Batten disease, a fatal neurodegenerative disorder of childhood, also plays a key role in normal cell function, Duke University Medical Center researchers have found.

16 Sep 2004

New biological principle and therapeutic goal for cancer treatment

Pioneering research on leukaemia cells can have identified their vulnerable spot. This new knowledge can now be used to produce more effective medicines.

14 Sep 2004

Disruption of protein folding causes neurodegeneration, mental retardation

Excess accumulation in brain cells of a fat molecule called GM1-ganglioside (GM1) disrupts the folding of newly assembled proteins into their proper shapes, triggering nerve degeneration and mental retardation in children.

10 Sep 2004

Transthyretin discovery may halt progression of Alzheimer's

In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer's disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease.

10 Sep 2004

Cell Death News and Research

Robotic microscope shows how mutant Huntington's disease protein affects neurons

Melanin is not only good for you, it also can be bad

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Researchers analyze the mechanisms and proteins that underlie mitochondria

Lithium can protect the brain cells involved in learning and memory from radiation damage

$10 million to establish a multidisciplinary research program in cancer nanotechnology

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Researchers reduce the toxicity of water-soluble buckyballs by a factor of more than ten million

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

New link in the growth of Ewing’s sarcoma

New gene therapy technique may help treat Alzheimer's disease

Scientists have corrected a flaw in cancer cells that lets them evade the normal cell-death process

New anti-inflammatory strategy for cancer therapy

Potential stem cells treatment for retinitis pigmentosa and other retinal degenerations

Protein that causes juvenile Batten disease also plays a key role in normal cell function

New biological principle and therapeutic goal for cancer treatment

Disruption of protein folding causes neurodegeneration, mental retardation

Transthyretin discovery may halt progression of Alzheimer's

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News