Confocal microscopy News and Research

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New way to detect neuropathy

Scientists have demonstrated a new technique for detecting a painful nerve condition known as neuropathy, which affects millions of people with diabetes and many other patients as well.

5 Dec 2007

Real-time 3-D analysis of breast cancer biopsies

A sophisticated microscope that offers a “real-time” 3-D analysis of tissue samples might, in the future, reduce the number of needle biopsies traditionally needed from women suspected of having breast cancer, according to recent research published at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center.

14 Nov 2007

Harvard 'Brainbow' helps chart neural circuits

By activating multiple fluorescent proteins in neurons, neuroscientists at Harvard University are imaging the brain and nervous system as never before, rendering their cells in a riotous spray of colors dubbed a "Brainbow."

1 Nov 2007

Transparent zebrafish help the study inflammatory breast cancer

What if doctors could peer through a patient's skin and see a cancer tumor growing? They'd be able to study how tumor cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body.

22 Oct 2007

Myoendothelial cells identified as new human source of stem cells with potential to repair muscle

For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.

5 Sep 2007

New model for signal transduction in cells

Among the key communication systems within a cell is the Wnt signaling pathway, which regulates embryonic development and whose deregulation can also contribute to cancer development.

28 Jun 2007

Multifunctional nanoparticle platforms for targeting and imaging cancer cells

There has been much recent interest in how nanotechnology will impact the field of medicine. Unfortunately, a number of promising nanostructured systems have turned out to be extremely toxic to humans, thus precluding their use in clinical applications and dashing hopes of an early success for the interdisciplinary field of nanobiotechnology.

21 Jun 2007

Scientists take a close look at early events in immune response

A Sandia National Laboratories research team led by Anup Singh is taking a new approach to studying how immune cells respond to pathogens in the first few minutes and hours of exposure.

4 Apr 2007

Nanotechnology continues to advance anticancer gene therapy

Given that cancer is a disease in which genetic errors play a major role, it should come as no surprise that many experts envision a time when gene therapy will play an equally important role in the treatment of cancer.

20 Nov 2006

Researchers figure out how nuclear pores duplicate before cells divide

Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.

28 Apr 2006

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine.

13 Aug 2005

Scientists watch agents of brain-wasting diseases invade and move within brain cells

Scientists for the first time have watched agents of brain-wasting diseases, called transmissible spongiform encephalopathies (TSE), as they invade a nerve cell and then travel along wire-like circuits to points of contact with other cells.

25 May 2005

Confocal imaging promises early detection of skin cancer

Detecting skin cancer early saves lives, but is a job for specialists. A new European system based on confocal imaging promises to improve detection and diagnosis rates by 20 per cent and to speed up the whole process considerably.

8 Mar 2005

What is Telomere crisis?

Telomere crisis is an important early event in the development of breast cancer, and its occurrence can be identified with precision, according to recent findings by a team of scientists at the Department of Energy's Lawrence Berkeley National Laboratory and the University of California at San Francisco.

11 Aug 2004

3-D micro-imaging technology licensed to Carl Zeiss Jena by Cornell

Biomedical microscopic imaging deep inside living tissue with unprecedented clarity could become routine and widely available with the signing of technology-transfer and collaborative-research agreements today (May 28, 2004) by Carl Zeiss Jena GmbH, a leading maker of microscopy instrumentation, and by CCTEC, the technology, enterprise and commercialization arm of Cornell University.

30 May 2004