Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Researchers turn normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

New target for the Fragile X mental retardation protein

Researchers in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine have identified a new regulatory target for the Fragile X mental retardation protein (FMRP), laying the groundwork for possible new treatments for Fragile X syndrome(FXS), the leading inherited form of mental retardation.

8 Jun 2007

Real-time, direct MRI monitoring of vector distribution within the brain

A team of scientists, led by Dr. Krystof Bankiewicz, University of California-San Francisco, presented this significant advance, which allows, for the first time, to adjust parameters of vector infusion while delivering gene therapy, giving surgeon full control over gene transfer technology.

3 Jun 2007

New platform for regulating the expression of therapeutic genes

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

Scientists have captured on video the intracellular version of a postal delivery service

Reporting in the journal Biochemical and Biophysical Research Communications (BBRC), bioengineering researchers at UC San Diego published videos of a key message-carrying protein called paxillin moving abruptly from hubs of communication and transportation activity on the cell surface toward the nucleus.

3 Jun 2007

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease typically characterized by the slow but progressive onset of shortness of breath or cough.

1 Jun 2007

New form of idiopathic pulmonary fibrosis found

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disorder from which most patients die within 5 years after diagnosis.

30 May 2007

Largest ever Affymetrix GeneChip Microarray study

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has announced that it has completed the largest ever Affymetrix GeneChip Microarray study for a plant experimental system in an academic research setting.

28 May 2007

Genetic data overturns long-held theory of limb development

Long before animals with limbs (tetrapods) came onto the scene about 365 million years ago, fish already possessed the genes associated with helping to grow hands and feet (autopods) report University of Chicago researchers in Nature.

24 May 2007

Diets high in salt may increase stomach ulcers

Scientists from the Uniformed Services University of the Health Sciences (USU) have discovered that diets high in salt may increase the virulence of the pathogen Helicobacter pylori (H. pylori), which is the most common cause of ulcers in the stomach and duodenum.

24 May 2007

High salt intake increases gene activity in the ulcer-causing bacterium Helicobacter pylori

Scientists have identified yet another risk from a high-salt diet. High concentrations of salt in the stomach appear to induce gene activity in the ulcer-causing bacterium Helicobacter pylori, making it more virulent and increasing the likelihood of an infected person developing a severe gastric disease.

24 May 2007

Exercise rejuvenates muscle tissue in healthy senior citizens

Not only does exercise make most people feel better and perform physical tasks better, it now appears that exercise, specifically, resistance training -- actually rejuvenates muscle tissue in healthy senior citizens.

24 May 2007

Peering into the body and visualizing its molecular secrets one step closer to reality

Peering into the body and visualizing its molecular secrets, once the stuff of science fiction, is one step closer to reality with a study from researchers at the Stanford University School of Medicine and the University of California, San Diego School of Medicine.

22 May 2007

MIT researchers uncover surprising difference in gene regulation in mouse and human liver cells

Scientists often study mice as a model for human biology and disease, because their basic biological processes are assumed to be essentially the same as those of humans.

22 May 2007

In some species estrogen plays a key role in aggressiveness

Imagine if a naturally occurring chemical in your body could help make you feel more calm and relaxed ? but it would only work during the long days of summer.

22 May 2007

Decoding gene expression in cancer tumors using noninvasive imaging

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

22 May 2007