Laboratory News and Research

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Mice and men should have more in common in clinical trials

Just as no two humans are the same, a Purdue University scientist has shown treating mice more as individuals in laboratory testing cuts down on erroneous results and could significantly reduce the cost of drug development.

30 Mar 2009

Intercell receives FDA approval of IXIARO, novel vaccine for Japanese encephalitis

Intercell AG (VSE: ICLL) today announced that the U.S. Food and Drug Administration (FDA) approved IXIARO(R), a new vaccine for the prevention of Japanese Encephalitis (JE).

30 Mar 2009

New cancer genomics web-based tools provide researchers a powerful new to visualize and analyze data

A Cancer Genomics Browser developed by researchers at the University of California, Santa Cruz, provides a new way to visualize and analyze data from studies aimed at improving cancer treatment by unraveling the complex genetic roots of the disease.

30 Mar 2009

Discovery of 'lock-like' molecule may provide new ways to starve cancer tumors or prevent drug side effects

Scientists have shed new light -- literally -- on a possible way to starve cancer tumors or prevent side effects from a wide range of drugs.

30 Mar 2009

Steroids and antihistamines alleviate clopidogrel-related allergic reaction symptoms

A clinical study of cardiac patients who suffered an allergic reaction to the widely-prescribed drug clopidogrel, also known by the pharmaceutical name Plavix, found that treatment with a combination of steroids and antihistamines can alleviate the allergic reaction symptoms thereby allowing patients to remain on the drug, say doctors from Thomas Jefferson University Hospital.

30 Mar 2009

FDA approves Afinitor oral tablets (everolimus) for advanced form of kidney cancer

The U.S. Food and Drug Administration today approved Afinitor oral tablets (everolimus) for the treatment of patients with advanced kidney cancer whose disease has progressed after treatment with other cancer therapies.

30 Mar 2009

Tea tree oil and silver effective in treating skin infections

In the fight against infected skin wounds, mixing tea tree oil and silver or putting them in liposomes, (small spheres made from natural lipids), greatly increases their antimicrobial activity and may minimise any side effects.

30 Mar 2009

Researchers find direct link between oxidative stress and inflammatory signals in the blood

The finding could lead to improved strategies for preventing several diseases by including antioxidants in the diet and for reducing the impact of inflammation in critically ill patients by adding cysteine to intravenous or tube feeding.

30 Mar 2009

Increased awareness and diagnosis of celiac disease would bring health care costs savings

A study published in Journal of Insurance Medicine by members of the Celiac Disease Center at Columbia University Medical Center has demonstrated an economic benefit to the diagnosis of celiac disease in a national managed-care population in the United States.

30 Mar 2009

Angiogenesis inhibitor improves glioblastoma survival by reducing edema

The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema - the swelling of brain tissue - and not from any direct anti-tumor effect, according to a study from Massachusetts General Hospital (MGH) researchers.

30 Mar 2009

New marker for breast cancer metastasis

Researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified a new marker for breast cancer metastasis called TMEM, for Tumor Microenvironment of Metastasis.

30 Mar 2009

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

Lantheus Medical Imaging, Inc has announced new data regarding the use of DEFINITY Vial For (Perflutren Lipid Microsphere) Injectable Suspension.

29 Mar 2009

DNA-based assembly line for precision nano-cluster construction

Building on the idea of using DNA to link up nanoparticles - particles measuring mere billionths of a meter - scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have designed a molecular assembly line for predictable, high-precision nano-construction.

29 Mar 2009

Scientists create vector, exotic genes from induced stem cells

A team of University of Wisconsin-Madison researchers reports that it has created induced human pluripotent stem (iPS) cells completely free of viral vectors and exotic genes.

29 Mar 2009

Discovery of mechanism of neurodegeneration in Alzheimer's disease

Tiny, toxic protein particles severely disrupt neurotransmission and inhibit delivery of key proteins in Alzheimer's disease, two separate studies by Marine Biological Laboratory (MBL) researchers have found.

29 Mar 2009

Scientists discover structure of a protein that makes cancer cells resistant to chemotherapy

A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells.

29 Mar 2009

Modified magnetic resonance imaging technique shows disease metabolism in action

Duke University chemists are using modified magnetic resonance imaging to see molecular changes inside people's bodies that could signal health problems such as cancer.

29 Mar 2009

Nanoparticles in cosmetics may be harmful to the environment

Using aquatic microbes as their "canary-in-a-cage," scientists from Ohio have reported that nanoparticles now being added to cosmetics, sunscreens, and hundreds of other personal care products may be harmful to the environment.

29 Mar 2009

Male circumcision reduces risk of herpes simplex virus type 2 and human papillomavirus

Heterosexual men who undergo medical circumcision can significantly reduce their risk of acquiring two common sexually transmitted infections - herpes simplex virus type 2 (HSV-2), the cause of genital herpes, and human papillomavirus (HPV), which can cause cancer and genital warts, according to a report in the March 26 issue of the New England Journal of Medicine (NEJM).

26 Mar 2009

Twin nanoparticle shown effective at targeting, killing breast cancer cells

A team of investigators at Brown University has developed a novel way to treat a class of breast cancer cells. The team has created twin nanoparticles that specifically targets the Her-2 tumor cell and unload a cancer-fighting drug directly into it. The result is a boost in antitumor activity while minimizing side effects. The findings of this study have been published in the Journal of the American Chemical Society.

26 Mar 2009

Laboratory News and Research

Mice and men should have more in common in clinical trials

Intercell receives FDA approval of IXIARO, novel vaccine for Japanese encephalitis

New cancer genomics web-based tools provide researchers a powerful new to visualize and analyze data

Discovery of 'lock-like' molecule may provide new ways to starve cancer tumors or prevent drug side effects

Steroids and antihistamines alleviate clopidogrel-related allergic reaction symptoms

FDA approves Afinitor oral tablets (everolimus) for advanced form of kidney cancer

Tea tree oil and silver effective in treating skin infections

Researchers find direct link between oxidative stress and inflammatory signals in the blood

Increased awareness and diagnosis of celiac disease would bring health care costs savings

Angiogenesis inhibitor improves glioblastoma survival by reducing edema

New marker for breast cancer metastasis

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

DNA-based assembly line for precision nano-cluster construction

Scientists create vector, exotic genes from induced stem cells

Discovery of mechanism of neurodegeneration in Alzheimer's disease

Scientists discover structure of a protein that makes cancer cells resistant to chemotherapy

Modified magnetic resonance imaging technique shows disease metabolism in action

Nanoparticles in cosmetics may be harmful to the environment

Male circumcision reduces risk of herpes simplex virus type 2 and human papillomavirus

Twin nanoparticle shown effective at targeting, killing breast cancer cells

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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