Laboratory News and Research

RSS

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

New discovery reveals how DNA regulates inheritance of disease mutations

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

21 Aug 2024

Maintaining healthy weight could lower risk of immune-mediated skin diseases in kids

Childhood obesity can contribute to the development of common immune-mediated skin diseases (IMSDs), such as alopecia areata, atopic dermatitis, and psoriasis, new research finds.

21 Aug 2024

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

21 Aug 2024

Hair follicles use unique sensor system to clean up dead cells

Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes-;mobile immune cells that migrate where needed to engulf problematic substances.

21 Aug 2024

Targeted therapy slows endometrial cancer growth in mice models

There may be a way to slow the growth of endometrial cancer through targeted cancer cell therapy, according to new research from the University of Missouri School of Medicine.

21 Aug 2024

Study identifies natural molecule that reduces pain sensitivity

Rutgers researchers have found a new way to manage the receptors that control the sense of touch, which could lead to treating chronic pain more effectively.

21 Aug 2024

Progress and future directions in esophageal cancer screening in China

Esophageal cancer, a highly aggressive malignancy originating in the esophageal epithelium, poses significant public health challenges in China, where it ranks sixth in incidence and fifth in mortality among cancers.

20 Aug 2024

First meeting of the International Health Regulations Emergency Committee reports on mpox surge

The Director-General of the World Health Organization (WHO), having concurred with the advice offered by the International Health Regulations (2005) (IHR or Regulations) Emergency Committee regarding the upsurge of mpox 2024 during its first meeting, held on 14 August 2024, has determined, on the same date, that the ongoing upsurge of mpox in the Democratic Republic of the Congo (DRC) and in a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the provisions of the Regulations.

20 Aug 2024

Global and Local Efforts to Take Action Against Hepatitis

In this interview, we explore global and local efforts to combat viral hepatitis with Lindsey Hiebert, Deputy Director of the Coalition for Global Hepatitis Elimination (CGHE), and James Amugsi, a Mandela Washington Fellow and Physician Assistant at Sandema Hospital in Ghana. Together, they provide valuable insights into the challenges, successes, and the importance of partnerships in the fight against hepatitis.

20 Aug 2024

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

More than half of women globally experience bacterial vaginosis (BV) -; an imbalance of naturally occurring microbes in the female genital tract -; at least once in their life.

19 Aug 2024

Study reveals time-of-day impact on cerebral malaria severity

A discovery by McGill-affiliated researchers could lead to more effective treatment of malaria and other parasitic diseases.

19 Aug 2024

Lecanemab effectively targets amyloid plaques in people with Down syndrome, study finds

People with Down syndrome are likely to develop Alzheimer's disease at a young age, with autopsy studies showing that by age 40 years, the brains of individuals with Down syndrome have amyloid plaques.

19 Aug 2024

Advancements in neoantigen vaccines offer hope for personalized cancer therapy

The saga of cancer treatment is marked by a relentless pursuit of effectiveness against a disease characterized by complexity and adaptability.

19 Aug 2024

Calls for humanitarian pause to safeguard polio vaccination efforts in Gaza

Two rounds of a polio vaccination campaign are expected to be launched at the end of August and September 2024 across the Gaza Strip to prevent the spread of circulating variant type 2 poliovirus (cVDPV2).

18 Aug 2024

ASTN2 gene knockout in mice reveals key autism-related behaviors

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, social communication, hyperactivity, and repetitive movements.

16 Aug 2024

New RNA molecules in extracellular vesicles could transform cancer diagnosis

Scientists at the Icahn School of Medicine at Mount Sinai have identified a new class of RNAs packed into tiny particles known as extracellular vesicles (EVs) that could revolutionize how cancer and other diseases are diagnosed.

16 Aug 2024

New exosome-based drug delivery system enhances ovarian cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

16 Aug 2024

Study reveals new insights into urea cycle's role in fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

16 Aug 2024

Tecovirimat shows no significant impact on mpox lesion duration in DRC study

The antiviral drug tecovirimat did not reduce the duration of mpox lesions among children and adults with clade I mpox in the Democratic Republic of the Congo (DRC), based on an initial analysis of data from a randomized, placebo-controlled trial.

16 Aug 2024