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Discovery of a new kind of messenger RNA molecule

Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection.

20 Oct 2005

Spliceosome crucial for processing non-coding RNA

The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. The active segments of a gene were termed exons, separated from each other within the gene by inactive introns.

20 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Neurobiologists gain new insights into brain and memory

We often make unwise choices although we should know better. Thunderstorm clouds ominously darken the horizon. We nonetheless go out without an umbrella because we are distracted and forget. But do we?

19 Oct 2005

Identification of a single chromosome region linked to specific language impairment

Researchers at the University of Toronto (U of T), Capital Health's Stollery Children's Hospital in Edmonton, Toronto's Hospital for Sick Children and their international collaborators have discovered a genetic abnormality that causes a type of language impairment in children

19 Oct 2005

Controlling antibiotic-prescribing practices in hospitals

Plenty of promising strategies exist to control antibiotic-prescribing practices, but no single method emerges as the best for hospital patients, according to a new review of studies.

18 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Correcting the timing of heart contractions through cardiac resynchronization therapy can be a lifesaver for people with advanced heart failure. But the procedure, as it is done today, fails in about 15 percent of patients.

18 Oct 2005

Cutting-edge research to develop this range of next-generation biomedical devices

Revolutionary new self-diagnostic devices to provide early warning of deadly and debilitating illnesses like cancer, diabetes and heart disease are the aim of a Euro 22.5m Science Foundation Ireland research facility to be established at Dublin City University.

18 Oct 2005

Discovery increases the yield of stem cells from umbilical cord blood

A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.

18 Oct 2005

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

A way to detect fragments of broken brain cells that leak into the bloodstream may help doctors more quickly and precisely treat people with severe head injuries or brain diseases, say researchers at the University of Florida's McKnight Brain Institute.

17 Oct 2005

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

By using a chemical analysis method developed for air-pollution testing, UCI chemists and pediatricians have found that people with cystic fibrosis exhale higher concentrations of sulfur compounds from their lungs than do people who don't have the disease.

17 Oct 2005

Hormone responsible for types of high blood pressure could also cause preeclampsia

Researchers at the University of Cincinnati (UC) Academic Health Center have found evidence of a hormone they say is responsible for certain types of high blood pressure (hypertension), and could also cause preeclampsia, a potentially dangerous condition that occurs during pregnancy.

17 Oct 2005

Men who smoke cigarettes may experience a significant decline in their capacity to father a child

Sperm from nearly two-thirds of the chronic smokers in the study failed a special test that measures the ability of sperm to fertilize an egg. On average, those men showed a 75 percent decline in fertilizing capacity when compared to nonsmokers. Lead researcher Loni Burkman, Ph.D., presented the results today (Oct. 17, 2005) at the American Society of Reproductive Medicine annual meeting in Montreal, Quebec.

17 Oct 2005

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Scientists have developed a new tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation, therapies that are widely used for the treatment of cancer.

17 Oct 2005

New genetic discovery may help explain why some people develop high blood pressure and others don't

It also gives new insight into how the kidneys govern the balance of salt in the body, a crucial task for regulating blood pressure. And, it reveals how a gene already linked to behavior and mental health can play a role in the body, as well as the brain.

17 Oct 2005

Researchers shed light on a key molecular switch in T helper cells

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.

17 Oct 2005

WWOX gene finding could lead to a new strategy for treating lung cancer

The research focused on a gene known as WWOX, which is lost or silenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work was led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Oct 2005

New treatment for the pediatric eye cancer retinoblastoma

Investigators at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer retinoblastoma that appears to be more effective than the current standard therapy, and more likely to prevent the recurrence of this cancer. A report on their work appears in the October 15 issue of Clinical Cancer Research.

17 Oct 2005

New findings on brain tumors called ependymomas

Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases, the researchers said.

17 Oct 2005

Laboratory News and Research

Discovery of a new kind of messenger RNA molecule

Spliceosome crucial for processing non-coding RNA

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

Neurobiologists gain new insights into brain and memory

Identification of a single chromosome region linked to specific language impairment

Controlling antibiotic-prescribing practices in hospitals

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Study demonstrates feasibility of a revolutionary, minimally invasive approach to introducing an electrical lead to stimulate the heart

Cutting-edge research to develop this range of next-generation biomedical devices

Discovery increases the yield of stem cells from umbilical cord blood

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

Hormone responsible for types of high blood pressure could also cause preeclampsia

Men who smoke cigarettes may experience a significant decline in their capacity to father a child

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

New genetic discovery may help explain why some people develop high blood pressure and others don't

Researchers shed light on a key molecular switch in T helper cells

WWOX gene finding could lead to a new strategy for treating lung cancer

New treatment for the pediatric eye cancer retinoblastoma

New findings on brain tumors called ependymomas

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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