Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

The risk of developing metabolic syndrome increases the more a person drinks

The risk of developing metabolic syndrome increases the more a person drinks – and beginning a heavy drinking pattern early in life seems to add extra risk, according to a first-of-its-kind study presented at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Metabolic syndrome associated with cognitive decline in elderly persons

Elderly individuals with the metabolic syndrome, a grouping of several common conditions including abdominal obesity, low level of high-density lipoprotein (HDL, the “good cholesterol”), hypertension, and high triglyceride and blood sugar levels, are more likely to experience cognitive impairment than those without this syndrome, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

Cranberry juice may help prevent gum disease

New research presented at a recent symposium suggests that cranberry juice may help prevent certain oral health problems, including diseases of the gums and teeth.

9 Nov 2004

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Lipid Sciences announced today that researchers have successfully used the Company's proprietary "selective delipidation" process to create a modified form of HDL ("good cholesterol") that is known to be more effective in reverse cholesterol transport, the body's natural process for removing lipids from arterial plaque.

8 Nov 2004

To avoid metabolic syndrome is relatively simple – 30 minutes of physical activity once a week

Metabolic syndrome is a condition that is affecting thousands of Canadians and is putting them at risk of heart disease and stroke, especially those aged 50 and over.

25 Oct 2004

Atypical antipsychotics commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance

Researchers from the Johns Hopkins Children's Center say a group of drugs known as "atypical antipsychotics" that are commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance, a condition that increases the risk of developing Type 2 diabetes and heart disease later in life.

21 Oct 2004

Diet high in soy could be good for the hearts and bones of premenopausal women

The results suggest that for cholesterol and bone density, the natural plant estrogens in soy may be most effective in conjunction with the body’s own estrogen – which would make it especially potent in women who haven’t reached menopause. They also point to the possibility the estrogen-soy synergy could have other benefits as well.

10 Oct 2004

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

When it comes to lipid profiles -- a key measure of heart disease risk-- it appears that African-Americans and women have it better than whites and men, according to a new study by Duke University Medical Center researchers.

7 Oct 2004

Short-term exercise significantly increases insulin action

Carefully controlling the amount of food and drink that formerly sedentary, overweight people ingest during and after short-term exercise has a significant impact on insulin action.

5 Oct 2004

Hibiscus flowers contain antioxidants that help control cholesterol levels

Hibiscus flower extract may have the same health benefits as red wine and tea according to new research by scientists in Taiwan. Hibiscus contains antioxidants that help control cholesterol levels and reduce heart disease, says the research in Journal of the Science of Food and Agriculture.

14 Sep 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

High blood pressure and high LDL-cholesterol add up to more than just double trouble for heart health, a Penn State College of Medicine study reports.

30 Aug 2004

Early cholesterol-lowering drug therapy reduces artery-clogging plaque

Early cholesterol-lowering drug therapy after hospitalization for acute coronary syndrome appears to reduce artery-clogging plaque, according to a study reported in Circulation: Journal of the American Heart Association.

25 Aug 2004

Effects of oxidative stress on atherosclerosis

Heart disease and stroke are the first and third leading causes of death among men and women in the United States and account for 40 percent of all mortalities, according to the Centers for Disease Control and Prevention.

9 Aug 2004

Updated guidelines for treatment of blood cholesterol

The National Cholesterol Education Program (NCEP) has updated its guidelines for treatment of blood cholesterol, suggesting that people at risk for heart attack and stroke would benefit from more intensive cholesterol-lowering therapies.

13 Jul 2004

Comparison of antiretroviral therapies shows that tenofovir DF and stavudine are equally effective

Results from a three year double-blinded trial which compared antiretroviral therapies show that the combination regimens of tenofovir DF and stavudine, are equally effective, though tenofovir DF has more favorable outcomes with respect to cholesterol levels and the nervous system.

11 Jul 2004

New guidelines for treating heart attacks

If your chest pain worsens and lasts more than five minutes, especially if you’re short of breath, feel weak, nauseated or lightheaded, call 9-1-1—you could be having a heart attack.

8 Jul 2004

Soy protein not effective in improving memory in post menopausal women

No beneficial effects were found on cognitive function, bone mineral density or plasma lipids when postmenopausal women age 60 years or older took soy protein supplements with isoflavones for one year

7 Jul 2004