Mitochondria News and Research

RSS

Metabolic switch required for cellular adaptation to hypoxia

Two new studies in the March Cell Metabolism reveal a survival mechanism by which cells adapt to oxygen starvation by ratcheting down their demand.

9 Mar 2006

Newly identified biomarkers may help reverse the ageing process

Lotions and potions that promise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work?

7 Mar 2006

Chocolate milk could be key to longer life

The popular saying goes that 70 is the new 60 and 60 is the new 50, unfortunately for much of New Zealand's ageing population declining muscle function means it simply isn't true.

7 Mar 2006

Ginkgo biloba reduces aggressive cancer risk in animal experiments

Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments.

27 Feb 2006

Study provides further insight into the molecular control of apoptosis

Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide.

23 Feb 2006

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered.

21 Feb 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

Getting old? Slowing down? Blame inefficient mitochondria

In mitochondria, the fuel is oxidised and builds up a pressure of hydrogen ions (protons). These force through molecular turbines and enable the cell to generate ATP, an energy unit that can be used throughout the cell.

6 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005

Link between diet and epileptic seizures studied

Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works.

13 Nov 2005

Anti-aging hormone called Klotho actions explained

Scientists recently discovered an anti-aging hormone called Klotho. Now, a new study shows that this protein acts by increasing the cell's ability to detoxify harmful reactive oxygen species.

7 Nov 2005

Blocking a signaling lipid can keep nerves from developing and may even cause neurons to die

Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found.

24 Oct 2005

Mitochondria and apoptosis research

The story of how mitochondria are recruited during times of stress to choreograph apoptosis--the cell's dance of death--is a story that fails to tell which particular set of steps the cells use most often, according to investigators at St. Jude Children's Research Hospital and the La Jolla Institute of Allergy and Immunology (San Diego, CA).

9 Oct 2005

PUMA protein offers critical insights for developing new anti-cancer drugs

The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital.

20 Sep 2005

It's pure science fiction! - human embryo to be created from two mothers

Scientists in Britain have been given permission to create a human embryo that will have genetic material from two mothers.

10 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

African-American women with mitochondrial DNA variant are at increased risk of breast cancer

African-American women who carry the 10398A mitochondrial DNA allele are 60 percent more likely to develop invasive breast cancer than African-American females without that genetic marker, according to research published in the September 1 issue of "Cancer Research."

1 Sep 2005

Study provides first steps toward individualized treatment of serious injuries

A multi-institutional research collaborative has begun to decipher the complex interplay of genes that underlies the body's response to major injuries.

1 Sep 2005

Immunity - another important function of the mitochondria

Researchers have discovered a surprise lurking inside mitochondria, the power plants that are present in every cell. It turns out that these powerhouses also contain a protein that triggers the immune system to attack viral invaders.

28 Aug 2005