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Roundup: Kan., Calif. budget cuts; Texas NICU costs; Katrina trial; Medco CalPERS contract 'dumped'

This list of programs cut in the California state budget includes a 10 percent reduction in what the state pays for Medi-Cal patients at all long-term care facilities $172.3 million and a 10 percent reduction in what the state pays to physicians who see people on Medi-Cal.

21 Mar 2011

Curemark reaches targeted enrollment in CM-AT Phase III clinical trials for autism

Curemark, LLC, a drug research and development company focused on the treatment of neurological diseases, announced that the company has completed its targeted enrollment of Phase III clinical trials for CM-AT, its autism treatment.

21 Mar 2011

Viewpoints: Celebrating health law anniversary (or not); Tricare's 'modest' fee increase; Funding Planned Parenthood

Since President Barack Obama signed the Affordable Care Act into law a year ago this month, we've heard endless partisan bickering about repeal efforts, legal challenges and fairness. But we've heard little about how the law is already helping secure the future of all Americans (Donna E. Shalala, 3/19).

21 Mar 2011

WaferGen, NuGEN collaborate to develop integrated workflows for gene expression profiling and target enrichment

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, and NuGEN Technologies, Inc., a leader in innovative genomic samples preparation, today announced they will co-develop and co-market simple, seamlessly integrated workflows for gene expression profiling and target enrichment to enable researchers to more easily achieve high-throughput, high-density real-time PCR with small, degraded, and hard-to-replace clinical specimens, such as formalin fixed paraffin embedded tissue (FFPE).

21 Mar 2011

Anacor enters $30 million loan agreement

Anacor Pharmaceuticals announced today that it has entered into a loan agreement led by Oxford Finance Corporation and partnered with Horizon Technology Finance Corporation to provide up to $30 million in capital. Anacor used $6.6 million to repay the remaining obligations under its loan agreement with Lighthouse Capital Partners and expects to use the remainder of the capital to fund development activities related to AN2690, AN2728 and AN2898.

21 Mar 2011

NeuroFocus unveils wireless headset to capture brainwave activity across the full brain

NeuroFocus unveiled the first dry, wireless headset designed to capture brainwave activity across the full brain today at the 75th Annual Advertising Research Foundation conference being held at the Marriott Marquis in New York. Developed over the last three years, Mynd™ combines medical-grade technology with mobility, leapfrogging current neurological testing methods.

21 Mar 2011

Prenatal alcohol exposure another risk for conduct disorder

Alcohol use during pregnancy is common and is associated with significant threats to the health and development of exposed offspring. Despite warnings from the Surgeon General to limit alcohol use if pregnant or contemplating pregnancy, a recent survey by the National Birth Defects Prevention Study(1) found that nearly one-third of women drank alcohol at some time during their pregnancy, with one-fourth of the women surveyed having drunk during the first trimester.

21 Mar 2011

Research outlines how cilia disease gene products regulate early cilium formation

An international collaboration jointly led by University College Dublin, University of Alabama and Simon Fraser University, British Columbia has outlined in the Journal of Cell Biology how cilia disease gene products regulate important aspects of early cilium formation and the integrity of the ciliary transport gate.

21 Mar 2011

Nektar initiates dosing in NKTR-181 Phase 1 clinical study for treatment of pain

Nektar Therapeutics today announced that the first subjects were dosed in a new Phase 1 clinical study to evaluate NKTR-181, the company's next-generation opioid analgesic candidate. NKTR-181 is being developed to effectively treat pain while addressing the abuse liability and serious CNS side effects associated with currently available opioid therapies.

21 Mar 2011

Investissement Québec provides financial support to Algorithme Pharma

Algorithme Pharma Inc., a Canadian clinical contract research organization, with facilities in Laval Québec, Montréal Québec, and through its sister company Simbec Research Limited in Merthyr Tydfil UK, today announced having secured the support of Investissement Québec in the form of a loan.

21 Mar 2011

Life Technologies enters clinical trials for DNA SBT platform for analysis of Human Leukocyte Antigen system

Life Technologies Corporation today announced that it is the first life science tools provider entering clinical trials to prove the safety and effectiveness of their DNA sequence-based typing (SBT) platform for analysis of the Human Leukocyte Antigen (HLA) system. Submission for 510(k) clearance of this SBT platform will follow completion of the clinical trials, which is anticipated this summer.

21 Mar 2011

Study on mandibular changes produced by skeletal anchorage assisted orthopedic traction

Today, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher T. Nguyen will hold an oral presentation on a study titled "Mandibular Changes Produced by Skeletal Anchorage Assisted Orthopedic Traction."

21 Mar 2011

Physical ill-health reduces life expectancy of people with severe mental illness

Physical ill-health is rife among the severely mentally ill in Britain, according to new research published today by the University of East Anglia (UEA).

21 Mar 2011

Elevations in 5 amino acids may signal future disease risk

Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear.

21 Mar 2011

More opportunities to develop therapies for protein misfolding

Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists at Brown University reports that cells can fix the problems themselves with only a little bit of help. The insight suggests that there are more opportunities to develop a therapy for protein misfolding than scientists had thought.

21 Mar 2011

Ethnicity, depression, lack of exercise are major risk factors for chronic fatigue syndrome

Chronic fatigue syndrome (CFS) is characterized by unexplained and debilitating tiredness and is associated with headaches, disrupted sleep, muscle pain and difficulty in concentrating. New research published by BioMed Central's open access journal BMC Medicine shows that ethnicity, depression, lack of exercise or social support, and social difficulties are major risk factors for CFS.

21 Mar 2011

Study on biodegradable tooth-binding micelles that inhibit Streptococcus mutans biofilm growth

Today, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher F. Cheni will hold an oral presentation on a research study titled "Biodegradable Tooth-binding Micelles Inhibit Streptococcus mutans (S. mutans) Biofilm Growth."

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

New synchrotron-based imaging technique offers more detailed chemical images

With intensity a million times brighter than sunlight, a new synchrotron-based imaging technique offers high-resolution pictures of the molecular composition of tissues with unprecedented speed and quality. Carol Hirschmugl, a physicist at the University of Wisconsin-Milwaukee (UWM), led a team of researchers from UWM, the University of Illinois at Urbana-Champaign and University of Illinois at Chicago (UIC) to demonstrate these new capabilities.

21 Mar 2011

Smoking during pregnancy increases risk of children becoming smokers too

New research has revealed that prenatal exposure to nicotine increases the vulnerability to nicotine self-administration in adolescent mice. The results support the hypothesis that adolescents with prenatal nicotine exposure are more likely to start smoking earlier than their peers and that they are also more susceptible to the addictive effects of nicotine, especially as a result of stress and peer pressure.

21 Mar 2011

Research News and Research

Roundup: Kan., Calif. budget cuts; Texas NICU costs; Katrina trial; Medco CalPERS contract 'dumped'

Curemark reaches targeted enrollment in CM-AT Phase III clinical trials for autism

Viewpoints: Celebrating health law anniversary (or not); Tricare's 'modest' fee increase; Funding Planned Parenthood

WaferGen, NuGEN collaborate to develop integrated workflows for gene expression profiling and target enrichment

Anacor enters $30 million loan agreement

NeuroFocus unveils wireless headset to capture brainwave activity across the full brain

Prenatal alcohol exposure another risk for conduct disorder

Research outlines how cilia disease gene products regulate early cilium formation

Nektar initiates dosing in NKTR-181 Phase 1 clinical study for treatment of pain

Investissement Québec provides financial support to Algorithme Pharma

Life Technologies enters clinical trials for DNA SBT platform for analysis of Human Leukocyte Antigen system

Study on mandibular changes produced by skeletal anchorage assisted orthopedic traction

Physical ill-health reduces life expectancy of people with severe mental illness

Elevations in 5 amino acids may signal future disease risk

More opportunities to develop therapies for protein misfolding

Ethnicity, depression, lack of exercise are major risk factors for chronic fatigue syndrome

Study on biodegradable tooth-binding micelles that inhibit Streptococcus mutans biofilm growth

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

New synchrotron-based imaging technique offers more detailed chemical images

Smoking during pregnancy increases risk of children becoming smokers too

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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