Serial Analysis of Gene Expression (SAGE) News and Research

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Special issue explores new research into collective memories of London bombings

Six years on from the devastating 7/7 London bombings and in the wake of the inquest into the attacks, a special issue of the journal Memory Studies, published by SAGE, explores new research into our collective memories of this tragic event.

7 Jul 2011

Hypertension variability during cardiac surgery may increase risk of death

For patients with hypertension undergoing heart surgery, large variations in blood pressure before, during, and after the operation are associated with an increased risk of death, reports the July issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Jun 2011

First audio data of naturally occurring spanking of children

In one recording, a mom spanks her 3-year-old 11 times for fighting with his sister. In another, a mom slaps her son for turning the page of a book while she reads to him. In still another, a mom spanks her 5-year-old when he refuses to clean up his room after repeated warnings to do so.

23 Jun 2011

Tips for healthy barbecue

Some people may be reconsidering plans to grill hot dogs and steak based on a new report supporting the link between red and processed meats, and increased colorectal cancer risk. But, experts at The University of Texas MD Anderson Cancer Center say that small changes to what — and how — you grill can keep cancer off the menu.

10 Jun 2011

Doctors place greater value on life-prolonging treatments rather than on quality-enhancing ones

Doctors are more apt to recommend a more costly therapy to patients if it were determined to prolong the patient's life rather than just improve quality, according to a recent study from Medical Decision Making (published by SAGE).

8 Jun 2011

Precision ophthalmic tint lenses reduce migraine, study shows

Precision tinted lenses have been used widely to reduce visual perceptual distortions in poor readers, and are increasingly used for migraine sufferers, but until now the science behind these effects has been unclear.

26 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

Most injured children are not being treated at trauma centers

Most injured children are not being treated at pediatric trauma centers, arguably the most appropriate location of care for young patients, according to a study to be presented Monday, May 2, at the Pediatric Academic Societies annual meeting in Denver.

2 May 2011

Seattle BioMed study to identify biomarkers for malaria vaccine design

In the first study of its type in the malaria field, Seattle BioMed has been awarded an $8.9 million grant from the Bill & Melinda Gates Foundation to identify biomarkers that will allow malaria vaccine design based on robust predictors of protective immunity.

28 Apr 2011

Catheter-related bloodstream infections in children

Hospitals can reduce the risk of life-threatening bloodstream infections in children with peripherally inserted central venous catheters by assessing daily the patient’s progress and removing the device as early as possible, according to a new Johns Hopkins Children’s Center study published online March 31 in the journal Clinical Infectious Diseases.

31 Mar 2011

Sage Bionetworks, AstraZeneca enter cancer research collaboration

Sage Bionetworks and AstraZeneca have initiated a collaboration to make new insights into certain cancers using advanced computational models of disease genetics. This deeper understanding of cancer will potentially help better match patients with appropriate treatments and might one day lead to new cancer therapeutics.

18 Mar 2011

$Guide to improving care of baby boomers' fragility fractures$

Guide to improving care of baby boomers' fragility fractures

Many Baby Boomers will experience a bone fracture as they age, and the current US healthcare system is not prepared to provide the necessary care required, according to a special monograph released in the January 2011 issue of Geriatric Orthopaedic Surgery and Rehabilitation (GOS), published by SAGE.

18 Mar 2011

UK doctors' and the public's attitudes differ over euthanasia, physician-assisted suicide

A review of research carried out over 20 years suggests that UK doctors appear to consistently oppose euthanasia and physician-assisted suicide (PAS). The findings - which appear in the latest issue of the journal Palliative Medicine, published by SAGE - highlight a gap between doctors' attitudes and those of the UK public.

10 Mar 2011

Plant distillation waste can increase yield, essential oil content in peppermint, spearmint

When essential oils are extracted from plants through the process of steam distillation, wastewater is produced and subsequently released into rivers and streams. Finding new uses for these unused by-products could benefit essential oil crop growers and processors as well as the environment.

7 Mar 2011

Physical therapy within 24 hours of knee arthroplasty can improve recovery, cut hospital stays

Starting rehabilitation sooner following knee arthroplasty surgery could pay dividends - for both patients and hospitals. Commencing physical therapy within 24 hours of surgery can improve pain, range of joint motion and muscle strength as well as cut hospital stays, according to new research in the journal Clinical Rehabilitation, published by SAGE.

6 Mar 2011

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Many people suffer from a devastating condition known as critical limb ischemia (CLI) that can lead to muscle wasting and even amputation. The disease is linked to the blockage of blood flow to the skeletal muscle and current treatment options include rehabilitative exercise and surgical bypass of blood vessels. New preclinical research suggests there may be a way to restore blood supply in skeletal muscle without traditional intervention.

2 Mar 2011

Tomato consumption can reduce cancer, osteoporosis and cardiovascular diseases

Eating more tomatoes and tomato products can make people healthier and decrease the risk of conditions such as cancer, osteoporosis and cardiovascular disease, according to a review article the American Journal of Lifestyle Medicine.

1 Mar 2011

3M's Infection Prevention Division, Sage Products enter second agreement

Sage Products and 3M's Infection Prevention Division have entered into an agreement which includes sales representation of Sage Products by 3M in select international locations. The new agreement is the second collaboration announced by the two companies in recent months.

15 Feb 2011

WIN Consortium proposes unique alliance to fight cancer

WIN Consortium proposes a unique alliance to fight cancer and invites you to join the 3rd annual symposium: Gateways to efficacy of cancer diagnostics and therapeutics to be held on 6th to 8th of July at the Palais des Congrès in Paris, France.

10 Feb 2011

SAGE Labs, Cofactor Genomics partner to sequence genomes for six widely used rat strains

Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich®, today announced that its SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat.

3 Feb 2011