Atomic Force Microscopy News and Research

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Atomic force microscopy is a type of scanning probe microscopy used to image the surface of a substance, but at an atomic level. It can map the surface structure of different substances to understand how different structures interact with each other. This is done using a cantilever, which is similar to a vinyl record needle.

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Christian Griesinger, director of the NMR-based Structural Biology department at the Max-Planck Institute for Biophysical Chemistry, talks about his research into neurodegenerative diseases using NMR to examine the dynamics of disordered proteins.

From Bruker BioSpin - NMR, EPR and Imaging 23 Feb 2015

Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Park Systems, a leading manufacturer of atomic force microscopy (AFM) and nanoscale metrology products, proudly introduces Park NX-Bio, a powerful 3-in-1 bio-research tool that uniquely combines scanning ion conductance microscopy (SICM) with AFM and an inverted optical microscope (IOM) on the same platform.

29 Jan 2015

Bruker Launches BioScope Resolve™ at the Sixth AFM BioMed Conference

Bruker unveiled the BioScope Resolve™, a biological atomic force microscope (bioAFM), at the sixth AFM BioMed Conference. The BioScope Resolve™ features excellent resolution imaging and comprehensive cell mechanics capabilities, and can be used with an inverted optical microscope (IOM).

From Bruker Nano Surfaces and Metrology 17 Dec 2014

Scientists reveal how bacterial nanodrills enter into our cells to kill them

A team of scientists has revealed how certain harmful bacteria drill into our cells to kill them. Their study shows how bacterial 'nanodrills' assemble themselves on the outer surfaces of our cells, and includes the first movie of how they then punch holes in the cells' outer membranes.

3 Dec 2014

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Cancer diagnostics and treatment options could be drastically improved with the creation of a 'designer' nanodevice being developed by researchers from the UK, Italy, the US and Argentina.

22 Oct 2014

Researchers discover new details of how autoantibodies destroy healthy cells in skin

University at Buffalo researchers and colleagues studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin.

11 Sep 2014

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of the NanoTracker™ Optical Tweezers system in the Laboratory of Molecular Genetics in the Leiden Institute of Chemistry at Leiden University.

9 Sep 2014

Scientists develop 3-D artificial enzyme cascade that mimics biochemical pathway using DNA molecules

Using molecules of DNA like an architectural scaffold, Arizona State University scientists, in collaboration with colleagues at the University of Michigan, have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.

26 May 2014

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Alzheimer's is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans.

22 May 2014

Positive results from pivotal clinical trial of Trophos’ olesoxime in SMA patients to be presented at AAN 2014

Trophos and AFM-Telethon today announce that data from the pivotal clinical trial of Trophos’ lead product candidate olesoxime in spinal muscular atrophy (SMA) will be presented during the 66th American Academy of Neurology annual meeting to be held in Philadelphia, PA, USA, from April 26 to May 3 2014.

29 Apr 2014

Research provides fresh insight into structure of sodium channels

Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much scientists do not know about the molecules.

18 Apr 2014

Trophos' olesoxime shows beneficial effect on maintaining motor function in SMA patients

Trophos today announces that top-line results from a pivotal clinical trial of its lead product candidate olesoxime in spinal muscular atrophy (SMA) show a beneficial effect on the maintenance of motor function in SMA patients. If approved, olesoxime could be the first treatment specifically developed for SMA patients.

10 Mar 2014

Innovation leads to faster drug therapies, increased understanding of proteins on microscopic level

Membrane proteins are the "gatekeepers" that allow information and molecules to pass into and out of a cell. Until recently, the microscopic study of these complex proteins has been restricted due to limitations of "force microscopes" that are available to researchers and the one-dimensional results these microscopes reveal.

17 Dec 2013

Generating an alternative to IVIG therapy: an interview with Professor Richard Pleass, LSTM

IVIG is a hugely successful biological with FDA approval for treating idiopathic thrombocytopenic purpura (ITP), Kawasaki disease, Guillain-Barré syndrome, Graves ophthalmopathy and numerous polyneuropathies.

11 Nov 2013

Trophos completes efficacy study of olesoxime in patients with Spinal Muscular Atrophy

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, has completed its efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy.

5 Nov 2013

Chemists discover mystery of how organic crystals form

New York University chemists have discovered crystal growth complexities, which at first glance appeared to confound 50 years of theory and deepened the mystery of how organic crystals form. But, appearances can be deceiving.

10 Oct 2013

Prairie Technologies acquired by Bruker

Bruker Corporation today announced that it has acquired Prairie Technologies, Inc. (Prairie), a provider of life science fluorescence microscopy products. The acquisition strengthens Bruker’s position in life science markets, adding to the Bruker Nano Surfaces Division’s existing life science atomic force microscopy (Bio-AFM) systems.

From Bruker Nano Surfaces and Metrology 13 Sep 2013

GW researcher to receive $1.3M NIDDK grant to study how type 2 diabetes develops

A George Washington University researcher will receive $1.3 million over the next five years from the National Institute of Diabetes and Digestive and Kidney Diseases for research that will help better understand how type 2 diabetes develops, possibly informing the development of novel treatments to reverse the disease.

30 Aug 2013

ASU expert receives $1.6 million grant to advance microscopy imaging research

At Arizona State University's Biodesign Institute, Nongjian (NJ) Tao has been designing advanced microscopy methods with the ambitious aim of capturing molecular-scale phenomena in living systems. The new techniques, which combine multiple imaging modalities, are poised to revolutionize the study of biology and the development of new drugs.

8 Aug 2013

Researchers fabricate nanotweezers that could be used to control and regulate enzymes

In new research, Hao Yan and his colleagues at Arizona State University's Biodesign Institute describe a pair of tweezers shrunk down to an astonishingly tiny scale. When the jaws of these tools are in the open position, the distance between the two arms is about 16 nanometers-over 30,000 times smaller than a single grain of sand.

5 Jul 2013